LOCUS       c00001_CAJKSH0..       17605 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CAJKSH010000001.1 TPA_asm: Lactobacillus gasseri isolate
            ERR1430442-bin.1 genome assembly, contig:
            NODE_5_length_334300_cov_11.418175, whole genome shotgun sequence.
ACCESSION   CAJKSH010000001
VERSION     CAJKSH010000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-20 02:13:32
            Original ID  :: CAJKSH010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 230012
            Orig. end    :: 247617
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17605
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[235012:242617]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..12605
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..17605
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17605
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1327..1605)
                     /locus_tag="ctg1_218"
                     /transl_table=11
                     /translation="MQAFYYAMPVLAVIVVGMYIFTSIKLHKFLWLSPVVYLALIGSVG
                     LWLTIGIDIFSVSKQGVLGLLVLEAILLEGIIEEYKYQKQNLSKNEE"
     CDS             complement(2055..2453)
                     /locus_tag="ctg1_219"
                     /transl_table=11
                     /translation="MSKKEKAIGIKILSWTITSVSLIGFLGDIYSYGFSMMRFNHVIAL
                     ILVVLLLISSIIFMSAKNLLEWNQKYGFFQWIGELITLPAFFLGSLYNSTHVWYSILFL
                     SLFGGGSILFIFVKYVRRRSRNKDKTKL"
     CDS             complement(2877..3158)
                     /locus_tag="ctg1_220"
                     /transl_table=11
                     /translation="MPVGYISIILLLLIILVDIVVSLKLHKLVKTSDVSNILILGIVTM
                     VIFALKDLSSFSWSSAIAIIFMSIVVLKDFYDEYQLQVKDGKNEKTSK"
     CDS             complement(3561..3794)
                     /locus_tag="ctg1_221"
                     /transl_table=11
                     /translation="MKVIEENEKEASRKEKWIILSISLVFGVLMNKLFLRLTSIDSFVL
                     SMLIGVGSMYVFECGYYYFRNDIQKMVRKVRG"
     CDS             complement(4063..4347)
                     /locus_tag="ctg1_222"
                     /transl_table=11
                     /translation="MNEAKLKEMLDKIKANSDIATDPEAQKLIETAIEKLDKKTNLQKV
                     VFNLKQDINLYSVAHGFKLPETLTKLQLLLDKDPDKWAVAGETMSLTNF"
     CDS             complement(4535..4990)
                     /locus_tag="ctg1_223"
                     /transl_table=11
                     /translation="MDAKEYESTEFYSYKFKNFSTMIIIPAAIFVLLLFIGSFFAIRQS
                     TVSSVGVVEPMVVIKKRNVNYDEGQVVTKHGQKWVAHVDQDSEVSLMPMMKAKGKVRIV
                     TYVPANKISSIKKGQKLNFSVPTADGLTSRITGKVTEIGVYPINVNK"
     CDS             complement(5001..7160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 336.1; E-value:
                     6.8e-102)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_224"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1066.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.3e-45, bitscore:
                     146.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEART
                     NLEGTTALGLVKTAQKFNFKTEAVKADMSLFDENSIQYPFIVHVLKQGELLHYYVVLKN
                     AKNYLVIADPDPSVGVIKMPKDRFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFPYMF
                     KQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSI
                     FSYGQNFLLNILGQRLSIDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALA
                     STVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPVYAVVILGFTKKFEKLNNEQMES
                     NAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFI
                     QLSLNVIVLWVGAKVVMQGQLSIGQLMTFNALLAYFIDPLQSIINLQPRLQSASVAQNR
                     LNEVYQVKSEFDKKTMVNNPALLEGTISYDKVDYRYGYGADVLKDINLKISQGEKLTIV
                     GMSGSGKSTMVKLLVDFFSPSKGQVTLNGHATSEINKHTLRSYVNYVPQTPYIFSGTVK
                     ENLLLGSRPDITEEDVIKACQIAGIDQEITNLPLQFETKLDEKAKILSGGQKQRLTIAR
                     ALLSPAKVFIFDEVTSGLDTITEKKVVDNLMKLKDKTIIFIAHRLAIAERADKVIVIDH
                     GQIVEEGSHSELMSKPGFYYDLVKG"
     CDS             complement(7173..7970)
                     /locus_tag="ctg1_225"
                     /transl_table=11
                     /translation="MKYSVIVCDDDEVLAKNLAKNIKYAVSNFTDDNPVYENIEINLEL
                     VATTFEQVVSYVVANDIQNAIYFLDIELSQNSEAKNGVDLAEFIKKQDPNAQIIFVTAY
                     DKYAPLTYRRRIGAIDYINKALDSREMMQRLEETLTGAVQSINNLMKSGRKELIYKIER
                     RVNKVEDTTIYYLENSTSQHKVNLITETGVAEFRSNISKINEENDFLVKVSQSCVVNPN
                     NINSIDFSKKTIKFPNGDEVVFARSCRKTVEDLLNKYPEINVK"
     CDS             complement(7967..9295)
                     /locus_tag="ctg1_226"
                     /transl_table=11
                     /translation="MTELYLLAILVSILLDIVLFYKVTKLKVSKAHFLFYLLLVIIGVI
                     CSFTGYKAILFYNVLAIVILNIIHKDNNNLTLISGTLIYIFSVDLIIELLRGVSLDVIE
                     KFNMSKNEIEWINLGCIFFFLITYLIVFFSANWIRKKLTGNNFRIFFWLILYLYLVTLV
                     IAVVYEGTKNIPPATIFFLSFLIVQFIFSLGLYYLMVKNQKVLLKKSEQDKIIQEQEQL
                     QEYTKYLEESEDELRAFRHDYRNMFNSLKISAQEGNTKEVIQKLDEYTKANLNAKAFEK
                     YRDVNHIKIKSLKSIIIAKLTEMYREHIPYNFECSSEITKLPKNINEIDLVRIVGISCD
                     NAIEESKVLIEQNQEAHIEIMAYSSERGEFEYEIQNKRSDSEISIKQIQQSGYSTKKSH
                     SGLGLANINSIKNKYENMTISYEVPEGYFDFYLVIEPEEESEE"
     CDS             complement(9296..9448)
                     /locus_tag="ctg1_227"
                     /transl_table=11
                     /translation="MMKDIRKENIVKATTLSEEEMIEVVGGKAVNGFIVPSSICKGIKW
                     WKFGR"
     CDS             complement(9589..10956)
                     /locus_tag="ctg1_228"
                     /transl_table=11
                     /translation="LTVQEKAAIRNWNPRYRRNVYLYLWIYGILGAVTGITNDAALSYF
                     DIVAPGLISGLNIFNAITALLMSLMIIWVHELGYRKILLILPPLTSIFLALTTITTNQI
                     VIMFAYIISWTAIGVYDLMYPLMWTSYVPKEIRTKMFTVVMVVNLVAQTILTFIGGKAV
                     VYFFSKMQGIPYDTASNLSAHTAQLSGSYLANYTNAFRIVLILTALVNVVAFILAIFIK
                     DEPKDYRTVGMKKPQTPEEKKKAFEALINKKTIMWILYIAGIQLGARLVVPYIPIYLND
                     YLHIPRGITSTINTFQTAAMFIGYFFAPFLAKKLGAIVSIAAGTLTCAPLMFLMANGRH
                     FGTGITLFVIVGVLLFLRSGLANATMPIQQEVQMIIVDKDMRPAFTAVVQIAYAVIEII
                     DGLFTAFYLLKTPAGYANAYYIATALYVVVSILLIVMFAKQYNWILDEKKSTSNEK"
     CDS             11118..11753
                     /locus_tag="ctg1_229"
                     /transl_table=11
                     /translation="VQSKRPIIIGIAGGSGSGKTTIAHEIYDQLQQDDHILIMTQDSYY
                     KNNDDLSMSERKKINYDHPDAFDMPLLVEQLRQLMNYKAVEMPVYDFTAHTRSEKTIHT
                     EPADIIILEGILVLGEENLRNLMSIKVFVDTDDDIRFIRRLERDTQERGRSVHSVIDQY
                     LKTVKPMYNQFIEPTKRYADIIVPEGGENDVAIDMLTTKIRSVLNTVK"
     CDS             complement(11791..12249)
                     /locus_tag="ctg1_230"
                     /transl_table=11
                     /translation="MKNNIFEKIYGTKLNLTLEEKEEVLEKSIQLGRILYIIEFLLLFG
                     VYFIFFFDAKLAFWLFLSINVVILYLIIPFEIALLRRKHKLVITYQTKGDKIKDIFLTT
                     VFFALISVAITIYFNWTKNHMVYIDLPTLIGIIIGSLLLGLTFTHPNK"
     CDS             complement(12246..12359)
                     /locus_tag="ctg1_231"
                     /transl_table=11
                     /translation="MKKLNKNELGMIKGGTNWGAVGSFATQNIKFPKRKKR"
     CDS             complement(12366..12605)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_232"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.1e-11,
                     bitscore: 36.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLSSLELKKIAGGGRRQIVGQCAKNIGFGAAIGAAAGSVKGVA
                     FGLEIGAVGGAVLGANMGAIKGAITCGGMVIGRR"
     CDS             complement(12752..13546)
                     /locus_tag="ctg1_233"
                     /transl_table=11
                     /translation="MIFEKLFSKENKKDEIVDVKLTDKEFNKLKIKLGVGDVIIEQGEN
                     FSVSFKGKKHYLPLLQLSDGKLQLKQKISLLETGEAELKIVIPQEVTLDSLDIQTNSGN
                     IEIVDTKAEKAYLKSTEGRVRVRRVAIAESLLESTDGNVTVRNSDLADGKLATYDGEIK
                     VSGSTLSRVVLNVTDGDMNLTDVTIDEGSANLKAGNFTLDHAVFKSDYEIKNIEGNNTV
                     WSANLKYARVRTANGQNNISFDPQSSGVVLSMTTVDGDNVVE"
     CDS             complement(13689..14207)
                     /locus_tag="ctg1_234"
                     /transl_table=11
                     /translation="LVIFGLHWGVVPLVAQQIAGTGESALNAIICSSMIAQGAAVLAVA
                     IKSKKEDLKELGFASTISAMCGVTEPAVYGISLRYKKVFISGCIGSAFGGLVTGLMHGT
                     MYGFTGGLIGFSSFFNPKHPTDLSSFYTFLIASAVTIVVSFIVTWVWGYNDSMVQGAKV
                     AKKKRPGSK"
     CDS             complement(14262..15653)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145:Glucose-specific phosphotransferase enzyme IIA
                     (Score: 47.7; E-value: 1.2e-14)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_235"
                     /transl_table=11
                     /translation="MKADTFKEENEIMVQDTTNLLAPATGAVIALAKTSDPIFSQGTMG
                     DGFGLTPTVGKVVAPVSGKISMVADTKHAVGIVTNEGLEVLVHMGVDTVGLKGAPFTIK
                     IENGQEVKAGDEIAEMDLDEIKAKGLDTTIMVLITNSADKISGLDVTEGEAKAGEVVAT
                     AYLKTSETEDTSSKKLSYPELAAFIIKNVGGKDNVNNVIHCITRLRFYLKDESKANDDV
                     LKNQRGILDVMHASGQYQVVIGNEVTNVFDEVVKQLGPLDSEAAPAPEDDGKNPVSKAF
                     GNLIGFITGSMSPIIGVIAAAGIIKGILALLTLPQLGSLLSIKSTAYITTSAIADSAFF
                     FLPVLVGYCAAKRLNSDPIIAAVIGGVLVYPQLVEWGKAFKTMFEVGGIKFEFLNYTYS
                     IFPMILAAWLAKKCEDWLKKWLPSYLQMIFIPLITVLVVSALTLMVTGPIIQGVANGIA
                     VFINW"
     CDS             15812..16537
                     /gene_functions="regulatory (smcogs) SMCOG1136:GntR family
                     transcriptional regulator (Score: 135.8; E-value: 3e-41)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_236"
                     /transl_table=11
                     /translation="MAQSKVSAIAQDLVDKIKHQQYKPGEYLPSEHQLMDLYGASRETI
                     RKALTNLTDLGLIQKIRGKGSIVLNLDRYAFPISGISSFAELNNQLGLKAETKVLLLQK
                     EDHLPTGFIKYFPEEKNSAGFHLERLRLIEGQADVLDCDYLLSPPINSLPKDAAKTSIY
                     NYLENKEKLEISYATKEISVCTVNQRIQDLLQLDNELAVLVASRNYLADTTKFELTLSY
                     HRPDKFKFVDFARRKKIKF"
ORIGIN
        1 taggtgcttc ttatctggtg cttgaatttt tgcattgtct gcaaaaaccc caccaagtaa
       61 tacttctttt aaagtatcat tatctttagc aaaaacatgc gttggtcctt ctttaatatg
      121 acctcgaact gcataacctt cgccagaaac atggtagctc ttttctaagg tccaaagttc
      181 tttaaccgtc atttcattct tagttaaagt tcccgtctta tccgagcaaa ttacagatgt
      241 cgatcctaac gtttctacgc tagataagcg cttaattaaa gcgtgtttct ttgccattct
      301 ttgaactgca ccagctaaag ataaagtaac tgttggttct aatccttctg gtataaaagc
      361 tacaatcatt cccaaagcaa agacaaagcc ttttactaaa ggatagtgaa caaagaaagt
      421 agcaattaag aagaaaataa tcccaattga aatggctaaa attgaaatct gcttagttaa
      481 agtatccagt tctttttcaa gcggactctt ttgctgagca acattttgtg ttaattcagc
      541 aatcttacca aaatcagtat tcatccctgt cttaacaaca actccagtaa cattaccctt
      601 catcatattg gtaccagaga aaatcatgtt attaagatca gcgtgatttt tcttcttcgc
      661 gtcttcaaca gcatgagcac ccttatgaac tgggttcact tcgcctgtca acgaagattg
      721 atcagcttga gccgttgttg cagcaattac acgaatgtca gctgggatat cgtctccttc
      781 ttcaagctta acgatatcgc cgggtactaa atcattagct aaaatctttt cttcttttcc
      841 gtctcttaca actcttgtat aagaaggaag catattcgct agcgcttcag ttgccttatc
      901 agcttgaaat tcttgccaaa aactaaaaat accgttaatg atatttactg cccaaatagc
      961 aattcctaat tgcactaaat cagcacaaaa agcaataata cctgctaccc aaagcagaat
     1021 agccattaaa ttagtaaaat tagctaaaaa tttttgccaa agcggctctt gttttgcttt
     1081 ggcaaaaata ttctttccat atttttgctg caatgtatga acttcatcaa ttgttaagcc
     1141 gctttgacta gtatttaatt ccttcagtgc atcttcaata gataattgag cgaccttaat
     1201 tatctcatca tttttatcat ttttagtcaa agttatcact tctattcctt tttacagatc
     1261 cattttagtt cacttttaaa aaatatgcac ataaagttaa tatactaaaa aagcgtagcc
     1321 cttcgactac tcttcattct tggatagatt ttgtttttga tatttatatt cttcgatgat
     1381 tccctctaaa agaattgctt ccaaaaccag taatcccaga actccttgtt ttgaaacaga
     1441 aaaaatatct atgccaatcg ttaaccataa accaacgctt ccaattaacg caagatatac
     1501 aactggtgaa agccaaagaa atttatgaag cttgattgaa gtgaaaatgt acattccaac
     1561 tacaattacc gctagcactg gcattgcata ataaaaagct tgcatagttc tacctacttt
     1621 ccaggccaag tattggtcgt attccagctg tttaaaccac caagccagcc attactcatt
     1681 gaaatttctt taatcttttc aagtaatgct tcttcatctt tttctaagtg aagatgatta
     1741 gcaaaacaaa tagtatttat atttttataa gttgcacgtg cttcatcaat ttcatcttga
     1801 acattatgtt ctaacttgtc taaggcaact tcaagctgtt ctaataagta ttcattgcct
     1861 tttctatcat aataagtctt agaagtgaga taaagtcatt caacacttgt tccaattcat
     1921 ttttcatgtt tttgtcctcc aaagagtagt tttgtttcca aatattatca tttattcatt
     1981 aattttacta tcattttttg taaaaattca aaagagactg attctgcgta ttcattgact
     2041 gatttagtat tttattataa ttttgtttta tctttatttc gcgatcttct tcgaacatat
     2101 ttaacaaata taaataaaat actgcctcct ccaaaaaggg ataaaaataa tattgaatac
     2161 cagacatgtg tagaattata taaactgcct aggaaaaaag ccggtaaagt aattagttca
     2221 ccgatccact ggaagaatcc atacttttga ttccactcta ataagttctt tgcagacata
     2281 aatataatag aagaaattag taataaaaca actaagatta aagctattac atgattaaaa
     2341 cgcatcatag aaaatccata actgtaaata tcacctagaa atccaattaa agaaactgat
     2401 gtaattgtcc aagataagat tttaatacca atagcttttt cttttttact catggatatt
     2461 tttcttactc tttaaacgtt gctgaatcct atctttgcca taataatacg tgatcgaaaa
     2521 cacactcata cttataattc cgacaaaaaa gcttagcatg atactgtcgc tattcgttac
     2581 atataaaaat agcttattca tgcaaaaggc aaagatcaca ctgagcgtaa ttatcgtcca
     2641 tgcttctgta tttgtatctt tactttgact aattttactc aatttcatgt agattcttct
     2701 ttctcatctg tcttagcttc acaagtttga acattaaata tcccaagatc acaccccaga
     2761 gaatgtttcc aagaattata caaatagtta atgtaccccc tactaacagg tctgttacag
     2821 tctcaagagt aaaaataatt gctccaacca gagtactaat aatgattaac tgtctattat
     2881 ttagacgttt tttcattttt accatctttt acttgtaatt gatattcatc ataaaagtct
     2941 ttcaaaacaa caatgctcat gaaaataatg gctattgctg agctccagga aaatgagctt
     3001 aaatctttca aagcaaaaat aaccatagtt actattccaa gtattaaaat atttgaaaca
     3061 tcagacgttt ttactagctt atgtaatttt agtgaaacaa cgatatcaac taaaattatt
     3121 agtaaaagta aaataattga gatatatcct acaggcattc tattttccct cctaaaattc
     3181 ttgctatgaa tttgatttta tcatttaaaa agtgctcaaa aataaaaaag acatatctgg
     3241 tcttattcat gacaaatttg atatttattt tcaaatttta tagcaaaatc atctaataaa
     3301 ataactccat attgcattat aaataattaa aaaacatcct actaagctca tttgcaaaac
     3361 taattttttc gaattttcat cctgcttaat agtaaattta attaaagcaa aaaatattaa
     3421 tccaacacta aaaacaatag tttttaccac tgattccata aactaccaat catacagatg
     3481 gctataccaa cataggttac taaaaatgca cctgcggaca gacctaatcc tgtccttaat
     3541 ctcctaagtt attgataaaa ttatcctcta acttttctaa ccattttttg aatatcgttt
     3601 ctgaagtaat agtatccgca ttcaaacaca tacatactcc ctactccaat tagcattgat
     3661 aaaacaaaac tatcaattga agttaaacgt aagaacaact tgttcattaa aacaccgaag
     3721 actagactta tgcttaaaat tatccatttt tcttttcttg aagcttcctt ttcattttct
     3781 tcaattactt tcatctctct caccttttaa ctcaatcctt ctactaattg tttaaatttt
     3841 agcattttaa agccagtaaa aataaaaaag aaccaaactg gccctgttta cgactaattc
     3901 ggttcctctt taatattgat ctgatttgtc tttcttgttg ggtaacattt tttcttatca
     3961 attaaatcac aatgctaaca gttcttaaaa cattattata tcttgtgatc ttccacatct
     4021 gcattaaatt tataaataaa aatattttta ttagattaac ttttagaaat tagtaagcga
     4081 catcgtttca ccagcaacag cccacttatc gggatcttta tctaataaaa gttgcaactt
     4141 agtcaaagtt tcaggcaatt taaatccatg tgctacagaa tacaaattaa tatcttgctt
     4201 tagattaaat actacctttt gcaaattagt tttcttatcc aatttttcaa tagcagtttc
     4261 aattaatttt tgagcttctg gatcagttgc aatgtcagag tttgccttaa ttttatctaa
     4321 catctctttt aatttggctt cgttcatctt tttatcctca cacaatataa tttaatatcg
     4381 ttttattcta tcaaatttat cttttattca ataccttatc taaaaaatag ttaaaatatg
     4441 tgctacgacc tgtcactatt gtggcattac cttgcattcc gtacttaaca tttatgtcgc
     4501 tagctttggt aatcgaaaca acttcataca tactctactt gttcacattt attggataaa
     4561 caccaatctc cgttaccttg ccagttattc tactagttaa gccgtctgct gtaggtacag
     4621 aaaagtttag cttctgcccc ttcttaatag acgagatttt attagcaggc acataggtaa
     4681 caatcctaac ttttcctttg gctttcatca taggcattaa actaacttcg ctgtcttgat
     4741 caacatgagc tacccatttt tgaccatgtt ttgtaacgac ttgtccctca tcatagttaa
     4801 catttctctt cttaattaca accattggtt caacaacgcc aaccgaagaa actgtactct
     4861 gtctaatagc aaaaaaagat ccaataaata aaagtagaac aaaaatagca gccggaataa
     4921 taatcattgt cgagaaattc ttgaacttat aggaatagaa ttctgtactt tcatactctt
     4981 ttgcatccat ctgtactcac ctatcccttc actaagtcat aataaaagcc aggcttactc
     5041 atcaattcgc tgtggctgcc ttcttcaact atttgaccat gatcaattac aattaccttg
     5101 tctgcacgtt ctgcaattgc tagacgatgg gcgataaaaa taattgtctt gtcctttagc
     5161 ttcatcaaat tatcaactac cttcttctcg gtaattgtat ctaagccact tgttacttca
     5221 tcaaaaataa atacctttgc aggagacaat aatgcccgag caattgttaa cctttgtttt
     5281 tgtccaccag atagaatttt tgctttttca tctaattttg tttcaaattg cagtggtaga
     5341 ttagttatct cttggtcaat cccagcaatc tgacaagcct ttattacatc ttcttcagtg
     5401 atatctggtc tagatcctaa caacaaattc tccttaactg ttccagaaaa gatatatgga
     5461 gtttgaggta cataattcac atatgaccgc aacgtatgct tattaatttc acttgttgca
     5521 tgtccattta atgtaacctg acctttactt ggcgaaaaga aatctactaa caacttaacc
     5581 atcgtagatt ttccagaacc actcattcca acaatcgtta atttttcgcc ctgactaatt
     5641 ttgagattaa tatcttttaa aacatctgcg ccatagccat atcgataatc aactttatca
     5701 tatgagattg ttccttctaa taacgctgga ttattaacca tagttttctt atcaaattca
     5761 ctttttactt gataaacttc atttaatctg ttctgcgcaa cactggctga ttgcagacgc
     5821 ggttgtaaat taataatact ttgcagtgga tcaatgaaat atgccagcaa cgcattaaaa
     5881 gtcattaact gaccaatgct caattgtcct tgcattacaa cttttgcacc aacccaaaga
     5941 acaattacat taagagataa ttgaataaat gtcttgagtg ctgtctgcaa actctcagtc
     6001 ttactatatt taaatgactt ctttaagtaa tctacaaatt gactatcaat tcttctatat
     6061 ctggtatctt cactatttaa agccttaata gtttcaattc cttgaatatc ttcaattaca
     6121 gaagaactaa gaaccgcatt actctccatt tgttcattat ttagtttttc gaacttttta
     6181 gtaaagccta aaattacaac tgcatatact ggtaaagcta ataatgtaat cccaaataat
     6241 gtcatatttt gcgctgctaa aactaatccc atcacaatca caattgagag gtctaagaag
     6301 agcgaaataa ctgtacttgc caaagcgtca ataattctac ttgcatcaga aaaacgtgaa
     6361 gtaatttcac ccgttcttct cgttacaaaa aattccattg gtaattcaaa aatatgcctg
     6421 atgtattgca gatttagatc aatacttaat ctttgaccta aaatatttag taaaaagttc
     6481 tgtccatagg agaagataga attgaagaca taagcaatta atagtccaac agctaagatc
     6541 gaaagagtct gataggttcc atctggaatg taagtatcaa ttattccttg aacaaaatat
     6601 gaactgcaaa tactaattat ggtcattaat aaagcggcta aaatgatatt aatcatcagc
     6661 cgcttttgtt taaacatata tggaaagaga gaccataaat tattcttctt ttctttgatt
     6721 ggttcaaagt cttcattagg aaccataaag agtgcaatcc ctgtccattc ttgagcaaac
     6781 ctatctttag gcatctttat tacaccaact gacggatcag gatctgcaat tactaaataa
     6841 ttcttagcat ttttaagaac tacataataa tgaagtagtt ctccttgttt taggacgtgg
     6901 acaataaaag gatattgaat actattctca tcaaataaag acatatctgc ttttacggct
     6961 tctgttttga aattaaattt ttgtgctgtc tttactagtc ctaaagcagt tgtgccttca
     7021 agattagtac gagcttcatg acgtaaatgt gctaaagata cgcgagaatg atattgcttt
     7081 aagatcattg ctaaacaagc aaccccacaa tccatctcat ccacttgtgg cacgtatacg
     7141 gatttatatt tgaataacat aagtcttacc ttttacttaa cattaatttc tggatattta
     7201 tttaatagat cctcaacagt ttttctgcaa ctacgagcga acactacttc atctccatta
     7261 ggaaacttta ttgtcttttt tgaaaagtcg atgctgttga tattatttgg atttactaca
     7321 caagattgag ataccttaac taaaaaatca ttttcttcgt taattttaga gatattgctt
     7381 ctgaattcag ctacaccagt ttcagttatc aaattaactt tgtgttgtga agtactattt
     7441 tcaagataat aaatagtcgt gtcttcaacc ttattaactc tccgttcaat tttatagata
     7501 agttcttttc ttcctgattt cataagatta ttgatacttt gaacggcgcc agtcaaggtt
     7561 tcttctaatc gctgcatcat ttctcttgaa tctaaggcct tattaatata atcaatagca
     7621 ccaattcttc tacgataagt taaaggagca tatttgtcat aagcagtaac aaaaattatt
     7681 tgtgcatttg gatcttgctt tttaataaat tctgctaagt ctactccgtt ttttgcttca
     7741 gaattttgac ttaattcaat atctaagaaa taaatcgcat tttgaatatc attagcgact
     7801 acataactta caacttgctc aaatgtagta gcaactagct ctaaattgat ttcaatattt
     7861 tcgtagactg gattatcatc ggtaaagtta ctaactgcat atttaatatt tttcgctaaa
     7921 ttttttgcta atacttcgtc atcatcacaa acgattacgg aatatttcat tcttcacttt
     7981 cctcctctgg ttcaatcacg agatagaaat caaagtatcc ttcaggcact tcataagaaa
     8041 tagtcatatt ttcatattta tttttaatac tattgatatt ggctaagccc aagccagagt
     8101 gacttttctt tgttgaataa ccgctttgtt gtatttgttt aattgaaatt tcagaatcac
     8161 ttcgtttatt ttgtatttca tattcaaatt caccacgttc gcttgaataa gccataattt
     8221 caatatgagc ttcttgattt tgctctatta atactttgct ttcttcaatc gcattgtcac
     8281 aacttatacc gacgattctg actaaatcta tttcattaat atttttaggc aatttcgtaa
     8341 tttcactgct acattcaaaa ttatatggaa tatgttctct atacatttct gttaacttag
     8401 caataatgat acttttgaga gattttattt ttatatgatt aacatctcta tatttttcaa
     8461 atgcttttgc atttaaattg gccttagtat attcatcaag cttttggatt acttctttgg
     8521 tatttccttc ttgtgcacta atttttaatg agttaaacat atttcgataa tcatgtcgaa
     8581 aagcacgtaa ctcatcttcg ctctcttcaa gatattttgt atattcttga agctgctctt
     8641 gctcttgaat tattttatct tgctccgatt tttttaataa tactttttga tttttcacca
     8701 ttagatagta gagacccaat gaaaaaataa actgcactat caaaaaagaa aggaaaaaaa
     8761 ttgtagctgg tggaatgttt tttgttcctt cgtatacaac agcaataact aaagttacta
     8821 gatataaata tagtattaac caaaagaaaa ttctaaaatt attacctgtt agcttttttc
     8881 taatccaatt tgcagaaaaa aagacaatta aatatgtaat tagaaaaaaa aaaatacagc
     8941 ctaaattaat ccattctatt tcgttctttg acatattaaa tttctcaatt acgtctaaag
     9001 aaacacctcg caataattct ataattaaat ccacactaaa aatatatatt aacgttccac
     9061 tgattagtgt aagattatta ttatccttat gaataatatt tagaattaca atggctaaga
     9121 cattatagaa taaaatagcc ttataaccag taaaactgca aataactcca ataattacta
     9181 gtaataaata aaataaaaaa tgagccttcg atacttttaa ttttgtaact ttataaaata
     9241 aaactatatc tagtagaata gacactaaaa tagctaatag atataactct gtcatctatc
     9301 taccaaattt ccaccacttt attcctttac aaatacttga tggtacaata aaaccattca
     9361 ctgcctttcc accaacaact tcaatcattt cttcttcact caaagtagta gctttaacaa
     9421 tattttcttt tctaatatct ttcatcattt cttctcctta aataatcaac attattttta
     9481 tgtcttaaat attaccatct ttcatccccc gaaaatacca aaaataccga atcagtcact
     9541 tttacgacta attcggtatt ttattattat tcttaagtta tcaattaact atttttcatt
     9601 agatgtgctc tttttctcat ctaagatcca gttatattgc ttagcaaaca ttacaattaa
     9661 taagatactt actactacat atagagcagt cgcaatgtag tatgcattcg catacccagc
     9721 tggcgtctta agtaagtaaa aggctgtaaa taatccatca attatttcaa ttaccgcata
     9781 tgcaatctga accacagcag taaaggctgg acgcatatcc ttatctacaa taatcatctg
     9841 tacttcttgc tgaatcggca ttgttgcatt tgctaaacca ctacgtaaaa atagcaaaac
     9901 tcctacaatt acaaaaagag taattccagt accaaaatgc cgaccattag ccattaagaa
     9961 cattaatggt gcacaagtta aggtcccagc agcaatagaa acaatggcac ctaacttctt
    10021 tgctaagaat ggagcgaaga aatatccaat aaacattgct gcagtttgaa aggtatttat
    10081 cgttgaagta attccccggg gaatatgcag ataatcattc aaataaattg gaatataagg
    10141 aacaaccaat cttgcaccta gttgaatacc tgcaatgtac agaatccaca taatcgtctt
    10201 tttattaatt aaggcttcaa aagctttctt cttctcttct ggcgtttgcg gtttcttcat
    10261 cccaacggtt cgatagtcct ttggctcatc tttaataaat attgccaata taaaagcaac
    10321 tacattaact aaagcagtca aaatcaatac tattctaaag gcattagtat aattagctag
    10381 ataacttcca cttagttgag cagtatgagc agataaatta gaagcagtat cataaggaat
    10441 accctgcatc ttgctgaaaa agtacactac tgccttccca ccaatgaaag ttaagatagt
    10501 ttgagcaact aagtttacaa ccattactac cgtaaacatc ttagttctaa tttctttagg
    10561 aacataagaa gtccacatta gaggatacat taagtcataa actccaattg cagtccatga
    10621 aataatgtaa gcaaacataa taactatttg gttagttgta atagtagtca aagccagaaa
    10681 aatagaagtt aaaggcggca aaatcagcaa aattttgcga taacctaatt catgtaccca
    10741 aataatcatc aacgacatta ataatgcagt aatcgcatta aagatattca aacctgaaat
    10801 taatcctggt gctactatat caaagtatga taaagctgcg tcattagtaa ttccagttac
    10861 cgcacctaaa attccgtaaa tccatagata taaatagaca tttctcctat atcggggatt
    10921 ccaattcctg attgcggctt tctcttgaac agtcaaagta aaaccttctt tttaaaacca
    10981 tacataacac tttcaatttt attttacttc acatgttcag aaaaaacaca tatttgtcaa
    11041 tattattgcc tgtaaatcta tcacagagcg taattttaag gtatcattgt aatagtttaa
    11101 aaaaggagat tttaattgtg caaagtaaac gccctattat cattggaatt gccggtggtt
    11161 caggtagtgg gaagacaacc attgcccatg aaatttatga ccaattacaa caagatgacc
    11221 atattttaat tatgacgcaa gattcttatt acaagaataa cgatgactta tcaatgtcag
    11281 aacgcaagaa gattaactac gatcatcctg atgcctttga catgccactg cttgttgaac
    11341 aacttcgtca attaatgaac tataaggcag ttgaaatgcc agtttacgac tttactgctc
    11401 atactagaag tgaaaagact attcacactg aaccagctga tattattatc ctagaaggta
    11461 ttctcgttct tggagaagaa aacttacgta atttaatgag catcaaggtc tttgtcgata
    11521 ctgatgatga cattcgtttc attagacgat tagagcgcga cacacaagaa cgtggtcgtt
    11581 cagttcattc agttattgat caatacttaa agaccgttaa gccaatgtac aaccaattta
    11641 ttgaaccaac taagcgttat gcagacatca tcgttccaga aggtggagaa aatgatgttg
    11701 ctattgatat gcttacaact aagattcgtt ctgtgttaaa tactgttaaa taaggcatta
    11761 taaaaccccg taggaaaatc ctacgaggtt ttatttattt ggatgagtaa atgtcaaacc
    11821 taacaaaagg ctaccgataa ttattccaat caaagtaggc aaatcaatat aaaccatatg
    11881 gttctttgtc caattgaaat aaatagttat ggcaacagaa attaaagcga aaaaaacagt
    11941 tgtcaaaaag atatccttta ttttatcgcc cttagtttga tacgtaatta ctaacttatg
    12001 ttttctgcgt aacaaagcaa tttcaaaggg aataattaaa tacaaaatta ctacattaat
    12061 actcaaaaaa agccaaaaag ctaatttagc atcaaagaaa aatataaagt acacgccaaa
    12121 cagcaataaa aattcaataa tatataaaat acgtcctaat tgtatacttt tttctaaaac
    12181 ttcttctttt tcttctaaag tcaaattaag cttagtgcca taaatctttt cgaaaatatt
    12241 atttttcatc tttttttacg cttaggaaat tttatatttt gtgttgcaaa tgatccaact
    12301 gctccccagt tagttccgcc cttaatcatt cctaactcat ttttatttaa ttttttcatc
    12361 tgtacctatc tccttccaat taccatacca ccacaagtaa tggctccctt aatcgcaccc
    12421 atatttgcac ctagtacagc accaccaact gctccaattt ctaatccaaa cgctacacct
    12481 ttaacgcttc cagctgctgc tcctatcgca gctccaaaac caatattttt ggcacactga
    12541 ccgacgatct gtcttcttcc tccacctgct attttcttta attctaaact agataatttt
    12601 tgcatttatc ctgtctcctt tatttattct gaattaaatc atacctggaa aatagacaaa
    12661 ttatagaaaa aagactaata aggctaacta ttgtattaaa attaatagtt ttgactgaat
    12721 caatacattt ctaacttcct gcattaattt tctactcaac aacattatct ccatcaactg
    12781 tagtcattga aagtacaacc cctgatgatt gcggatcaaa ggaaatatta ttctgaccat
    12841 ttgcagttct tacacgtgca tatttcaagt tggcactcca cacagtgtta tttccttcga
    12901 tattctttat ctcataatcg ctcttaaaga cagcatgatc taacgtaaaa ttaccagctt
    12961 ttaaatttgc actgccttca tcaatagtta catcagttaa attcatatcg ccatctgtaa
    13021 cattcaaaac tactcgtgac aaggttgagc cagagacttt aatttctcca tcataggttg
    13081 caagctttcc atcagctaaa tcgctatttc ttacagtcac gttaccatcg gtagattcaa
    13141 gtaacgattc tgcaattgca actcgtctca ctctgactct gccctcagta gacttaagat
    13201 atgccttttc agctttagta tcaactattt caatatttcc gctattagtt tgaatatcta
    13261 gactatctag cgtcacttct tgaggaatga caatttttaa ctcagcttct cctgtttcaa
    13321 gcaagctaat cttctgctta agctgcaact ttccatcaga taattgaaga agaggcaagt
    13381 aatgtttttt tcctttaaaa ctaacactga aattctctcc ctgctcaatg attacatccc
    13441 ccacacctaa ttttattttg agcttattaa attccttatc ggttaattta acatcaacta
    13501 tctcatcttt tttattttct ttagaaaaaa gcttttcaaa aatcatagcc tttcccccta
    13561 acttacgcct taattaaatt attattaatt atattaatat gatttaatat ttgcaactcc
    13621 tgagcgcaaa aaacaacgct gaaattttca acgttgtttt attgtttatc taaatcaaat
    13681 aaattttttt acttactacc aggtctcttt ttctttgcaa ccttggcgcc ttgaaccata
    13741 ctatcgttat agccccaaac ccaagttaca ataaatgaaa ctacaattgt tacagcacta
    13801 gcaattaaga aagtatagaa acttgataag tcagttggat gttttggatt aaagaatgaa
    13861 gaaaatccaa ttaatccacc agtaaagcca tacattgttc cgtgcattaa accagtaaca
    13921 agaccaccaa atgcagaacc aatacaacca gaaataaata ctttcttata tctcaaacta
    13981 ataccataaa cggctggctc agtaacacca cacattgcag aaatagttga agcaaatcct
    14041 aattctttta agtcttcttt cttagactta atagcaacag ctaatactgc agcaccttga
    14101 gcaatcattg atgaacaaat aattgcgttt aatgcacttt caccagttcc ggcaatttgt
    14161 tgtgcaacaa gtggaacaac accccagtgc aaaccaaaga taaccaatac ttggtaaaat
    14221 ccaccaataa tgaatccgcc gatccaacca gatgcgtgaa cttaccaatt aatgaagaca
    14281 gcaatcccgt tagcaacacc ttgaataatt ggaccagtta ccattaaagt caatgcagat
    14341 acaactaaaa cagtaattaa tgggataaaa atcatttgta agtatgatgg tagccacttt
    14401 ttaagccaat cttcacactt tttagcaagc catgcagcta aaatcattgg gaaaattgag
    14461 taagtatagt tcaagaactc aaacttaatc ccaccaactt caaacatggt cttaaaagct
    14521 ttaccccatt caactaattg agggtaaaca agcacaccac caattactgc tgcaatgatt
    14581 ggatcggaat tcaatctctt tgctgcacaa taaccaacta aaactggcaa gaagaagaag
    14641 gctgaatcag caattgcact agtagtgata taggctgtac tcttgatact aagtaaacta
    14701 cctaattgag gcagagtaag caatgccaaa atacctttaa taataccagc tgcagcaatc
    14761 acaccaataa ttggactcat tgaacctgta ataaatccaa ttaaattacc aaaagctttt
    14821 gaaactggat ttttaccgtc atcttctgga gcaggagctg cttcactatc taaaggtcct
    14881 aattgcttga ctacttcatc aaagacatta gttacctcat taccaattac aacttggtat
    14941 tggccagaag catgcatcac atctagaatt ccacgttgat tttttaaaac gtcatcgtta
    15001 gctttacttt catcttttaa atagaaacgt aaacgggtaa tacagtgaat tacattgtta
    15061 acattatctt taccgccgac atttttaata ataaaagcag ccaattctgg ataggataac
    15121 tttttacttg aagtgtcttc tgtttctgaa gtttttaagt aagctgttgc gacaacttca
    15181 ccagcttttg cctcgccttc agttacatca agtcctgaaa tcttatcagc tgaattagta
    15241 atcaaaacca tgattgttgt atctaatccc ttagccttga tttcatctaa atccatttca
    15301 gcaatttcat cgccagcttt aacttcttga ccattttcaa tcttaatcgt gaatggtgca
    15361 ccctttaaac caactgtatc aacgcccatg tgaactagca cctctagtcc ttcattagtg
    15421 acgattccga cagcatgctt agtatcggca accatactaa ttttccctga gacaggtgct
    15481 acaacctttc caacagttgg agttaatcca aatccatctc ccattgttcc ctgagaaaag
    15541 attggatcag aagtcttagc taaagcaata accgctccag tagctggagc taataaatta
    15601 gtagtatctt gtaccataat ttcattctcc tctttgaaag tatccgcttt catttatctt
    15661 gactcaaata ttatgcttgt ctgtacaagt tgtcaatact atttcatgaa aaagcttact
    15721 ttttctttta aataagcatt ttatagataa taaagttttt ctttacttgt ctaaacaagt
    15781 gtatataatt aaagacaaag gaggattttt tatggctcaa tccaaagtta gtgctattgc
    15841 tcaagactta gtagataaaa ttaagcatca acaatataaa cctggcgaat atctccctag
    15901 tgaacatcaa ttaatggact tatatggggc ttcaagagaa acaattcgaa aagcacttac
    15961 taacttaact gacttaggct taattcaaaa aattcgcgga aaaggctcaa tagttttaaa
    16021 tcttgatcgc tacgcttttc ctatttcagg aattagcagt ttcgctgaat tgaacaatca
    16081 attaggactt aaagctgaaa caaaagtttt acttttacaa aaagaagacc atttacctac
    16141 tggctttatc aaatattttc ctgaagaaaa aaacagtgct ggttttcatc ttgaacgctt
    16201 gcgattaata gaaggacaag ctgatgtctt agattgcgac tatttgcttt cacctcctat
    16261 taattcactt ccaaaagatg ctgcaaaaac ttctatttat aattatttag aaaataaaga
    16321 aaaattagaa atttcctatg caacgaaaga aatttctgtc tgcacagtta accaaagaat
    16381 tcaagattta cttcaactag ataacgaact cgcagtgctg gtcgcaagca gaaattattt
    16441 agctgatacg actaaatttg aactaactct gtcatatcat cgacctgata aattcaagtt
    16501 tgttgatttt gctcgcagaa aaaagattaa attttagaaa ggatcccagc gatgaataat
    16561 ttaggcaata aagtaattta tcaaatttac ccaaaatctt tttacgattc aaataatgat
    16621 ggtattggcg acttacgtgg tatcatcgaa aaaattgact atatcaagaa gctaaatgta
    16681 gatttcattt ggttcaatcc tttttttgtt tccccacaaa atgacaacgg ctatgacatt
    16741 gctgactata aaaaaattga tcctcgattc ggaaccatgg acgacttcga agaactggtc
    16801 gctaaattaa aagcaattaa tgttaatgtg atgctcgata tggttttaaa tcactgctca
    16861 acagaacatg aatggttcaa aaaagcccta gccggcgata aaaaatatca aaaatttttc
    16921 tatcttagaa aaggcaaaga tggacaacta cctaataact ggcaatcaaa atttggtggc
    16981 ccagcttggt ctaagtttgg tgacacagat tattattatc ttcatcttta tgaccctact
    17041 caagcagacc ttgattggca taatcctgaa gttcgagcag cattaattga tgtagttaat
    17101 ttttggcgtg gtaaaggtgt gcatggtttt cgctttgatg taattaatgt tactggaaaa
    17161 gataatgtat tagttgattc aaccgaccca gttcaagaaa agtcgcttta tactgataca
    17221 cctgtagttc aacaatatct aaaagaatta aatgcaaaat ccttcggtca agacccggaa
    17281 tcagttactg ttggagaaat gtcatcaact acgattgaaa attcaattgc ttatactcgt
    17341 cccgaagatc atgaactctc aatggtcttc actttccatc acctcaaggt tgactataaa
    17401 aatggtgaaa aatggtctaa gatgcctttt gattttaaga aattaaaaga tattatgctt
    17461 acctggaaca gtaagattga tcaaggtggc ggctggcagg ctctcttctg gaataatcat
    17521 gatcaacctt gggcattaaa tcggtttggt gatacaggaa aatatcataa taaatctgct
    17581 gaaatgttag ctcttactct tcatc
//
