LOCUS       c00009_CAJNQH0..       11226 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CAJNQH010000009.1 Bacillus subtilis isolate NRS6137 genome assembly,
            contig: NODE_9, whole genome shotgun sequence.
ACCESSION   CAJNQH010000009
VERSION     CAJNQH010000009
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 20:57:56
            Original ID  :: CAJNQH010000009.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 118031
            Orig. end    :: 129257
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11226
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[128031:128301](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10270)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11226
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11226
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             495..1070
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 62.5; E-value: 1.2e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg9_117"
                     /transl_table=11
                     /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYH
                     FFPNGKEELAIEAVTYTGKIVEHLIQKSMDESSDPVEAIQLFIKKTASQFDNTESIKGI
                     PVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMIEGG
                     IMLSLTNKDKTPLLLIAEQIPVLVRKKG"
     CDS             1162..2175
                     /locus_tag="ctg9_118"
                     /transl_table=11
                     /translation="MKTLWKHSLPKEKMPYLLRSGEGERYLFGRQVATVMANGRSTGDL
                     FEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPAGTPHS
                     YRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVSNERFAEAAAVADIVF
                     LDEGKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRIVAAQKNTDGQFIVVS
                     SEGPKGDRIVYHYHEHHTETFYCLEGQMTMWADGQEIQLNPGDFLHVPANTVHSYRLDS
                     YYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALRFDRVLQNIEALDLKVMKP"
     CDS             2283..3491
                     /locus_tag="ctg9_119"
                     /transl_table=11
                     /translation="MSSLQPTLTNERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSML
                     GKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVPLY
                     VRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLFSIP
                     FMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGMLTYNP
                     LNFFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYNVTDK
                     EICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYH
                     YGLGLYGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLSWQPIVKK
                     TKV"
     CDS             complement(3521..3976)
                     /locus_tag="ctg9_120"
                     /transl_table=11
                     /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFVINSVFVAGAVATNP
                     YMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGER
                     VSVGQAIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK"
     CDS             4233..4658
                     /locus_tag="ctg9_121"
                     /transl_table=11
                     /translation="MSKKNSVAIMTAISAFLFCAVIVAASLSPLAGTGAAANQFNSAGM
                     WSAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLS
                     EVIFVLGVSLAAAAVNVIWFVAAFRSGAEKTSVNTLT"
     CDS             4759..5991
                     /locus_tag="ctg9_122"
                     /transl_table=11
                     /translation="MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVLQPTAAYAAETV
                     FSQNNGASGFLPGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGAVI
                     DGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFI
                     DKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKLKTNG
                     VVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGNIYAGN
                     QDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGDMNWSFY
                     TDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWNYQTDSNVVSSPQLAEDGTLYI
                     GSYTKLMAFGK"
     CDS             complement(6055..7254)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 97.4; E-value: 1.1e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg9_123"
                     /transl_table=11
                     /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEI
                     AKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLI
                     SGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYL
                     LLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFTATAY
                     DTISRYWQPFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRFEKKIEKNPYLALTSLDS
                     MGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFSLNSGVG
                     AIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQIEKSQQV
                     "
     CDS             complement(7251..9494)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 407.3; E-value: 1.9e-123)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_124"
                     /sec_met_domain="Asn_synthase (E-value: 2.8e-95, bitscore:
                     312.9, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1e-44, bitscore: 144.4,
                     seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSK
                     VGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVI
                     VHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIK
                     SLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNER
                     KTASYWSLQDILLRQGYHENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSA
                     AVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPES
                     YKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAEN
                     PSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVL
                     TKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKS
                     LTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEH
                     IHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETPSVQLDITSHLESITIKDWHSQE
                     GDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFIQFIVSEEDVGAW
                     LHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR"
     CDS             complement(9515..9997)
                     /locus_tag="ctg9_125"
                     /transl_table=11
                     /translation="LEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDI
                     VSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHT
                     WYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ"
     CDS             complement(10001..10270)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_126"
                     /sec_met_domain="PF05402 (E-value: 1.8e-12, bitscore: 40.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.7e-09,
                     bitscore: 30.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.7e-09, bitscore:
                     30.4, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDGK
                     VSIHDICSKIVNEYDVDYQTCLEDCMELFELLIDHEAIKVKQGA"
     CDS             complement(10270..11004)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 103.3; E-value:
                     2.4e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_127"
                     /transl_table=11
                     /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMGT
                     GPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYADQY
                     ADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVILDTFNPQGSHLEIMRKQIKEPEYF
                     RFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQNDQS
                     ADHEIESVTWMLTIEKEKEGAL"
ORIGIN
        1 cgaaagtcga gacggccgca ttgttgaccc atgtgtcaaa gcggccgaat gtgctgatcg
       61 cggtttctgc gatgcggttg acgtcctctt cttttccgac atccgccttt acccatatgg
      121 cgtcgtgccc tttttcctta agttcatcag tgagctcctt cagcgcctct tcatttcgcg
      181 ctgctgccac gacctttgcg cctttttcag ctgccattct cgccgtgaca agtccgattc
      241 cgcttgaagc gccggtaatg acgatcacct gatccttgag ttttttcagt ttgatcttcg
      301 ttttcatgcc ggggttctgt tgttcaagct gctctgtatt cgtgactgaa tgatcgattg
      361 tcattgagag atccctccta gacgctgttt ttgtacatta ccccatccgg aagggtctta
      421 ccccttttga caatcacagg gttctttttt atattatata agtcgctcta ccatacctag
      481 gagggaatgt tttaatgact agcagaggag attcacgtga aaaaatcctt cacacggcgt
      541 cacgtctgtt ccagctgcaa ggatatcacg cgacaggttt gaaccagatt gtaaaagaaa
      601 gcggtgctcc aaaaggatcg ctttatcact tttttccgaa tggcaaagaa gaattagcaa
      661 ttgaagcggt tacatataca ggtaagatcg ttgaacatct gatacagaaa agcatggatg
      721 aatcctctga tcctgttgaa gcgattcagc tttttatcaa aaaaacagcc agccaatttg
      781 ataacacaga aagcattaaa ggtattccag tcggtttgct ggcgagtgag acagcgttaa
      841 tcagtgaacc gctgcggacg gtttgcatga aggtgtttaa aagctgggaa gcggtttttg
      901 ccagaaaatt aatggaaaac ggatttgcag aagaagaagc aaatcagctt ggaacgctga
      961 ttaattcgat gattgagggc ggcatcatgc tttcgttaac gaataaagac aaaacgcctc
     1021 ttcttctcat tgccgaacaa ataccagtgc tggtgagaaa aaaagggtag cattttgtta
     1081 tcctttctcc tacaattata tagaacggtc tagtcagaaa gttatagtat atagactggt
     1141 ctaaattgga ggaaatgatt tatgaaaaca ttatggaaac attcattgcc taaagaaaaa
     1201 atgccttatt tgctccggag cggagaaggc gagcgctatc tgttcggcag acaggttgcc
     1261 acggtgatgg cgaatgggag gagcacaggt gatttgtttg agatcgtgct tctttccggg
     1321 ggaaaaggag atgcctttcc gcttcacgtc cacaaggaca cacatgaagg aattctcgtt
     1381 ttggacggga aactggaact gacacttgat ggtgaacgct atttattaat atcaggtgat
     1441 tatgcgaaca ttccggcggg aacaccgcac agctaccgga tgcagagcca cagaacaaga
     1501 ctggtatctt acacgatgaa aggaaacgta gcgcacttgt attccgttat tgggaatccg
     1561 tatgatcacg ctgaacatcc gccgtacgca agcgaagaag tctcaaacga gcgatttgca
     1621 gaagcagccg ctgtagcgga cattgtattt ctagatgaag gaaagcctgc atgttcggcc
     1681 aaattagcgg aacttacaga gctgccagat ggagcggttc catacgttct tgaatctgga
     1741 gaaggagatc gcctgttgac tggagatcag cttcaccgca ttgtggctgc acaaaaaaat
     1801 acagatggcc agtttatcgt cgtatcctct gaaggcccta aaggtgaccg aatcgtttat
     1861 cactaccatg aacatcatac agaaacattt tattgccttg aaggtcagat gacgatgtgg
     1921 gcagatggcc aggaaattca gctgaatccg ggagatttcc tgcatgtccc tgcaaatacc
     1981 gttcactcct atcgccttga ttcttactat acaaagatgg tgggcgtatt ggttcctggt
     2041 ttatttgaac cgtttttccg gacgttaggc gacccgtatg aaggccacat cttcccatgt
     2101 gagcctcagg ctttgcgctt tgatcgcgtt ttgcagaata tcgaagcatt agatttaaag
     2161 gtgatgaaac cataaagatg acaagattgt aaggttttca tgccggcctg acacctaaat
     2221 cgatgtttcc gcgcttcatt ttttcatacc cttaaggtac agaaaaaagg agcgtgatgg
     2281 ctatgtcttc attacagccg actttaacaa atgagcggat cggtgtgctt gatgtgctga
     2341 gaggaatggc gattttcggc atcttatttg tcaatctggc acatttcagt tatccggata
     2401 tgtatttgtc tatgcttgga aaagagaatt ttttcatgga taagtggtct gaagctgatt
     2461 ttgccgccgc agatatactg aaattcttca ttcaaacaaa atgtatttta ttgttttcct
     2521 ttttatttgg atttggcatg gttgtcatga tggagagagc agaaaacaaa gggaaacggt
     2581 ttgttccgtt atatgtgaga aggttaatgg cgcttctctt gtttggaacg attcatgcct
     2641 ttttgatatg ggacggggat attttaacag aatatgccct gctcggtttt gtcctgctct
     2701 tgtttcgaaa agcaaagccg aaaacactgc tgatatgggc ggtctctttg tatcttctgt
     2761 tttccattcc gttcatgttg acaagttttg atcaatcaaa cggacaggaa tgggtacaag
     2821 cggtaacaca gcaggcaaaa caagcgattc atgtttatgg aagcggcagc ctgaaggata
     2881 ttgcagaaca gcggatccac gaccgtcttg tttacatgtc ttcgaatggc atgcttacgt
     2941 ataatccgct caacttcttc tttgcatcca ttccatattt cagcatgttt ttgctgggag
     3001 ctgcggcagc gaaatctcgg tacttgcatg aaccggaaaa gcatcgcaaa ggattaaaac
     3061 gattatggat ggctgggctt gtcatcggca tcggcgccca ggtgctgtac aatgtaacgg
     3121 ataaagaaat atgtttgctg attggcgcgc ctttcctcat gtttttctat gttacaacgg
     3181 ttgtctatct ttatcataaa acaagagtga gaacagtgct gcaatcattc tccgctgttg
     3241 ggaggatggc atttaccaat tatctgatgc agtctattgt atgtacttgg attttttatc
     3301 attacggctt gggcctgtat ggaaaagtgt accctgctgc cggtgtgctc attacaattg
     3361 ctgtttgtgc cgttcaaatg gtcttcagcc acctttggct tcgtgtcttt cggatggggc
     3421 cgtttgagtg gctgtggaga agcgctacgt atctgtcgtg gcagcctatt gtaaagaaaa
     3481 caaaagtcta gatgcctatt ggcgtctaga cttttttcta ttatttatac acgacacgtg
     3541 ttttgcaaat gatgtcatgc aggccttttt tctctccaaa ggcgatcatg ataaacccga
     3601 tataaaagat gattccagat aagatatagg caaagtaacg gccaattgcc tgtccgacag
     3661 aaacccgttc gccttgttca ttgaccactt tcaggccaag aatttttttg ccaagtgtgc
     3721 cttgcatttt agaagctgtg agcagcccgt aatataacac actgatgacg atcatgatca
     3781 gcatagtagg caaaaatgca agcgtcatgt attttactaa atactcttct tccgtcatgt
     3841 aagggtttgt tgccacagcc ccagctacaa aaacagaatt gatcacaaat agaataatat
     3901 aactaggaac agatacaata atgccatcaa taaaataagc taaaaaacga atccaaaatc
     3961 ctgctggttt ttccatgtat ttttctctct cctctgaatt aatctggaat agtatacttt
     4021 gaaaaacaag tacatgcaat atggtatggt gataaaatcc tgatattaca gaaaaatgag
     4081 tcttttatcc tttgtttttt actatataaa tatactagaa agaagcatag catttgtgta
     4141 tgtattctgg aattttttaa aaatataatg aatataacat tcaacttact tataataaaa
     4201 aaggttaata tttctattaa aggaggagtt tgatgtcaaa aaaaaatagc gtggcgatca
     4261 tgacagccat ttctgcgttt cttttttgcg ccgtgattgt ggcggcttca ctttcgccgc
     4321 tggccggaac gggagcggcg gccaatcagt ttaattcagc tggcatgtgg tcagctgtcg
     4381 gtatgatcct tgtcttgtat ttcattccat ttctcgttta tatgctcgga gtcgatgcaa
     4441 tgaggtatgt catggcggtg ctttgcggct tcgggctttt gattcatttg tcttcggccg
     4501 gttttatctt gatgtttagt ttctttagtg accatctgct ttctgaggtg atctttgttt
     4561 tgggagttag tctcgctgcg gctgctgtca acgtcatttg gtttgtggct gcatttcgat
     4621 cgggtgctga aaaaacgtcc gtgaatactc ttacatagtt ttctagtttg tgatgttttt
     4681 gtgaaataga tttataaaat ggatgaatat gttatgatgg tcgaaaatta gaagttacat
     4741 ataatggggg tctcaatgat ggtcaagtca tttcgtatga aagctttgat tgcgggagct
     4801 gcggtggcgg cggctgtttc ggccggtgct gtttctgatg tgcccgctgc caaagtgctt
     4861 cagccgacag ctgcttatgc ggcggaaacg gtgttttctc aaaataatgg agcatctggc
     4921 tttttgccag gaagatatga tgtacaagcg atggcgcctg ccatgtttaa ctggtcacgc
     4981 gaaagccggt tcgccggaaa tacagacggg acgctgaaat ggcaaaacga catcagaacg
     5041 actccgcaaa atggagcggg ggctgtgatt gacggagacg gcacagtata tcttcattcc
     5101 agagacgggg aaatgaaagc ctttaatcca gacggctcag tcaaatgggt gacgggcaat
     5161 cttggaaaaa catatacgca atctcctgta cttgggacca acggcgttat ctatttggca
     5221 tcctatgaca aaaagattta ttttattgac aaagaaacgg gagaaatttt aacaacggtt
     5281 ccgttaagcg gcgggccaag ctctgaaacg gtgatcggtt cagacgggac gttgtatttc
     5341 tcaacacttg ataattatgt tcacgcgatc aaaccgacgt caaaatcaac ctggacagag
     5401 cgctggaagt tgaaaacaaa tggtgtcgtc agctctgtgc cggtgcttgc caaaaacggc
     5461 accgtgtatg tcggcacata taattacgtg ttttatgcga tcaactccgg aaccggacag
     5521 gtgaaatggt ccagaacgac gtcaaatgcg tttaaaggat atccggtgat tgataaggac
     5581 ggaaacattt atgccggcaa ccaagatgga cagctgtatg cttatacatc aacaggcagt
     5641 ttgaaatgga cattcccgct aaacgggttc tccagctcat ctcctgcgat tgatcataat
     5701 ggcaatatct acatcggctc aggaagcggc gagctgtttt ccatcagcaa aaacggggat
     5761 atgaactggt cattctatac agacggccct gtcagaacgg cgccgctgat tgacgcgaag
     5821 ggaacggttt atttcgggtc agatgatatg aaggtttatg cggcagacgc aaacggcaat
     5881 gaattatgga actatcaaac cgacagcaac gtcgtgtctt ctcctcagct cgctgaggac
     5941 ggaacgcttt atattggaag ttatacgaag ctgatggctt ttgggaaata actgaataga
     6001 atagcagaag accttctttt aataagaagg tcttcttact gtgatacaaa acatttacac
     6061 ttgctgggat ttttcaatct gaactttcat atcattgtct ttaatcttag gcactatcgt
     6121 ataaaggata atagggatta atagaaatac agctacaaca acaaacatgg cagagagccc
     6181 aaaggctgcg gaaatgatgc cgaaaatgac accggaaaga atttctccaa ttgctcctac
     6241 ccctgagttt aacgagaaaa gtgtgttctt gtatgaatcg gggaaaaact tatttaagta
     6301 acttgttacg atcggatgat gaatatcttc aattgcaagc aaaaacgctg tacatggaat
     6361 gcccagcggc ctgaatgctc tagacaatag aaaagtcatg accatgccca tggaatccaa
     6421 tgaggttaaa gcgagatatg gatttttttc gatcttcttt tcgaacctga tggttaatgt
     6481 caaaagaacg agagcggtaa accctcctag ggcaaaaata tatcccagtg acttttctga
     6541 aaagcctaaa tcactcaaaa aaggctgcca gtaacgggaa attgtgtcat aggctgtggc
     6601 tgtaaagaaa ccggctatga cgattaaaag aacccttttt ttgttaaaga taatttttaa
     6661 actttctttg ataatcttta tcgaatcatg ttggttctga tccccatgat ttgtttcgga
     6721 aacagaaggg actttaataa atacagacat ccaaataaat agtaataagt agatcaccat
     6781 aacgagcagg aaaggaaaat agatatttaa tgaatacaaa tacccgctgg caatacttcc
     6841 aataattaaa aaagtgatta gcaattgtgt gtttttcatc atttctttgc cgaatcgatc
     6901 ttcccctgcg acacggctca tccaagtttc aaaagaaccg gaaattaagg aatctgataa
     6961 agcccatatg atcatagcca gtatgcaaat agcagctgaa tcgataaaag ggaagaaggc
     7021 ccatgtaagg atggagaaaa agaatgaact ggcaattgaa attttaattc cataacgatc
     7081 agcaaaaacg ccggaaggaa cttcaaatat aagcttagca atttcaagta ccgctcccat
     7141 taatccaatc tgaaggaaat cataatcttt agatatcaga taaagaatcc aaataggcga
     7201 aaaaatcccc attgctaatc ccctaagtgc ggaaaacgaa taaaagatgc tcatctatat
     7261 gctccttctg gcagattttt ttgtttgatc aaaatgatat tgtgttcgat ggcttcttga
     7321 atatatttgg ccacttcttc aaggctgaca ccatgtctgt ctaaaatcgt atgaagtgtg
     7381 tcttttccat taatatcgca gagaatatgc agccaagctc cgacgtcttc ctccgaaaca
     7441 ataaactgaa taaatccttc ttccgcaatg tagatgcaat gctcactatc gctttccggt
     7501 cttaacagag tgacgccagg gtttagcgcc aaaatatctt gtccttcaca cttattggct
     7561 gagatattta aacggctggc aatatcacct tcctgtgagt gccagtcttt tattgttatc
     7621 gattctaaat ggctggttat gtctaattga acagaagggg tttctttagt catttttgat
     7681 aaaagtccca tgttcaccag tcttaataaa aattcaaaat ttgtaaactc aggatcatcc
     7741 tccaaatatg tcatgatggc atgaatgtgt tcaacctgta ttatgctgga ggcatcgctg
     7801 tgagagaagg cctcctctat aagctgataa ttgtttttct tcagaagatg aaacatcatt
     7861 ttatgtgtat atctcacgtc cttaccatag aaaaaaggaa cctttggccg gtgggtatag
     7921 cttgtatgca gctcatttgt taatgatttt cgcaataccg acttatccca taacaagtct
     7981 ttacggagtc catcaggtat tccgcaaacc cattcaacaa gccgatggtc caagaacggt
     8041 acacggtttt cgatatgatt agccgcggcg atccgatctt catgccagca attatacatt
     8101 tgcagatcac ggtattttgt caggacatac gattgccaag gatctgcttg gctggaatca
     8161 ttgctcttta aataagaaag gtttatagga gaaagtccaa aatgctcctc ccacactcta
     8221 aagatatttc cctgcagccg atgcagccgg ttcatctcca tcgtattgac cgattcaata
     8281 aatccttccc aacttgggtt ctcggctggt gaaagtgtcg tgctgtaacc gccgttaaat
     8341 tcgtcgctgc cctggccggt cagcatgact ttcaggtttg gccttatcgc tttggcatac
     8401 ttatgtaaat gaaacttata taattgttcc ggtccgcaaa acggtgtttc acagatccat
     8461 aacaaatgtt tatatgactc tggttgtaat aactcatcgt tccctaattg atagagaacc
     8521 tgatgatttg gaaggtgtaa atctttagcc agccaatggg catattttgc atcttcattt
     8581 gtaaatgtac tttggcttaa tactgtaaac gtatggagat cctgtttttc tgcagcaaaa
     8641 tgtgcgactg cagctgaatc aatgccaccg ctaagaaaca acccgacttc aacgtcgctt
     8701 tgtaaacatc tatggactga atctgccagc agttctctat atccttcaat caggtcatcg
     8761 ggatggagat tctcatgata gccttgcctg agcaaaatat cctgtaaaga ccaatagctt
     8821 gctgtttttc gttcatttgt tgtcaaatta atttcgagat aatggccagc atcgagattt
     8881 tggatgttta caaaaaagga agtggtttct ttatgattac tggctgcttc cccgcttagc
     8941 caaatgtctg agagtgcttc tttccaatta aattggcggg gacagtgagg atgagaaaat
     9001 agggatttta tttcagaggc aaatataagc tcgtgtttta gctctgtgta aaaaagcggt
     9061 ttaatcccaa agcggtcacg aactaaaaat actttgtttt tatttttgtc ccaaatggct
     9121 attgaaaaca ttccgatgat gtcgtctaca aatccaatcc ctttttcttc atataaatga
     9181 acaattactt cacaatcaga tgtcgtttta aacatatgat tgtgtaaaga agccttcagt
     9241 tctttatagt tataaatttc tccatttacc ataacgacga ttgatccatc ctcatttaaa
     9301 aagggctgct gtccatttac aaggtcaaga atggacaatc gccgaaatgc aaagccgact
     9361 ttggaatcaa tatgatattg ttcatcatcc ggtcccctat agctgatggc atctgccatg
     9421 cctttcaata tatgaaaggt acattcctga gaacggggag cagccagatt tataataccc
     9481 gcgagcccgc acatatgtct ccctcccaat agcgttattg atgtttatag atataagctg
     9541 tctctacatc tgtttctttt acaatatcga ttttaattcc gagacgtttt gcgttttcga
     9601 ttgcgagaat ggaagcgtac gcagaaaatt cttcgggatc aatttcaaaa taaaaaaagg
     9661 cctcactagg ttctttttca taccaagtgt gggtatttac gacatattta tcttctgttt
     9721 caaacaattc aattttgtca taaagtaaac gtcttccttt tataaagagt tccacaaatg
     9781 atccaactgg ttgttggctg ttaatgtgtc tccactcatc ataatatcct ctttcctcat
     9841 attgctcgtg aatccagctt acaatatctt gatgagtcaa tccttgtttt ttggcaaagg
     9901 caagcagagt gatgatgtaa tttacgattg atttagaacg gtgtgtactc agctcatgta
     9961 catcgtctgg taaagcaagc actttttgtt tttccaattc tcatgccccc tgcttaactt
    10021 tgattgcttc atgatcaata agcaactcaa acagctccat acaatcttct aagcaggttt
    10081 gataatcaac atcatattca ttgacgattt ttgagcaaat atcatgtatg ctgaccttgc
    10141 cgtcgatatg gttataaata tctgatgcca tttcatttaa agtgatgccc ggctctataa
    10201 taatgctttt caaatatttt cttgatggca tttctggatt tttggataaa acagttgatt
    10261 cattgatcat tacaatgcac cttccttttc tttttctatc gttaacatcc atgtgacaga
    10321 ctcaatttca tgatcagcac tttgatcatt ttgttcccac aggggagcat cctccagctc
    10381 atctaagctt tctataaaat cctccggtaa aaagtgaaag gtttctaatg aataattggg
    10441 aatgccggca tcctgaacaa actggtgaat gtcttcaaag gaataacttt cttcaaatgc
    10501 ctctcttaca aacctgaagt attccggttc tttgatttgt tttcgcataa tctctaaatg
    10561 gcttccttgg ggattaaatg tatccaaaat gacaattttt ccgcccggag ccagaactct
    10621 atagcactct ttaagtcctt taacaacgtc ttcccaatga tgcaggcaag agtaggagac
    10681 gatgaagtca gcatattggt cagcgtaaga taaatggtgg acatcttcca aatcaaatga
    10741 aatcaggctg cttactccgc tttttttagc ttcttcttga gcgatttcat gcatggccgg
    10801 gttaatatcg acagcatgca cgtgcgcatt tgttctttta gccaactgaa tgcttaaata
    10861 acctggacct gtgcccatat cgataatgac tttgtttttg ggggaataca tccgggacag
    10921 tctggcgcca agcaaggggt aaagatagga ttggtaaaga tcaacaaatt ctttgtacgt
    10981 tctgcattct tcagccgtaa tcatcttcag catcctcctt atcaagttgg cgtgatagcc
    11041 tcaaacgtta atcgttttgg ataagattaa tgaccgccag ctgctacagc gcggcgcaat
    11101 tcaaaaaggc gaggtttctt ataagctttt ttcattgagc atccctccta aaatagagta
    11161 ctagatgtca aatgctatat gagattaatg gccgccagct gctacagcac ggcgcagttc
    11221 aaaaag
//
