LOCUS       c00038_CAJVVT0..       12602 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CAJVVT010000038.1 TPA_asm: Streptococcus salivarius isolate
            DRR077041_bin.2_metaWRAP_v1.1_MAG genome assembly, contig:
            ERZ1744232.60, whole genome shotgun sequence.
ACCESSION   CAJVVT010000038
VERSION     CAJVVT010000038
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.0.0
            Run date     :: 2022-06-19 22:26:17
            Original ID  :: CAJVVT010000038.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12602
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1287
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="ICLFLYLINKRVSIGHFLIILFCRIAYTKICNSLSWKFLFYFNEE
                     IFYLLLSFFISRKPYLQSKLKIFNALLPTTLNNISFRVIIFFIFPLFGISVETIKVNYL
                     IAVSSSFLTILLSFLLIKLFKESFGVIQKGRLAPLISKSIIIADIIMIAYTFTQQYLVY
                     LENTTHTSTLIIRKLIVVIYLVFFFIMLIFLDRNIRATIQSQLDFQKDIQLSHLTNYNK
                     QIENLYQSVRSFRHDYANILTTLKLGIDQNDMAIVKEVYDSVLKDSDKHLKSKTFDLTR
                     LINIEDNTIKSLLAAKFLEAEENNIDISLDIPETIKLEGMEMVDFITVISIFLDNAMEA
                     SIQSDIPKMHIGYFNHGNKQIFIVQNSTQEEFIPISSLFERGVSSKGDHRGIGLANVRN
                     ILDNYQNISLKTESMTFAFTQELNISKKA"
     protocluster    1..12602
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2776:11613]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2777..11613
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12602
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12602
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1374..1775)
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MKLKNISSRVLRFSRVVTAVLAVFLISTSISLYKSKTSPEIWLAV
                     GALALVVIFVNGLLYRLLKKRPDSVNPLTIRQSFIVFLVISFLVLCVEFYTLLTFSDIT
                     DRIVLAVLMLLLILCDFLAYLQVRNYFKQ"
     CDS             complement(2121..2288)
                     /locus_tag="ctg38_3"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIGMGLANLFRSLDAVHHTINLFGLTLLLYSL
                     LLKKWAQFKK"
     CDS             complement(2777..3007)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_4"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.6e-18,
                     bitscore: 56.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQTMNTFETLDLEALANVEGGGCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             complement(3166..3606)
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MYQELTDEEIKAAAEFVDANHFIDKLPEGYDAPVSERGSSFSTGQ
                     RQLLAFARTVASQPKILILDEATANIDSETEAIVQNSLAKMRQGRTTIAIAHRLSTIQD
                     ANCIYVLDKGRIIEHGSHEELLALGGTYHKMYSLQAGAMEGE"
     CDS             complement(3591..4910)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 125.1; E-value:
                     5.5e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALAFLLSTTVIKSIIPLVA
                     SYFIDHYLHDMNQAASLILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGILSSFISAIFIFVTTLYTMMMLDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVVIIEKTRALLSDINAKLSESIEGIRIIQAFNQEKRL
                     KKEFDAINEEHLIYASRSMSLDSLFLRPAMSLLKLLGYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTDAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVSKGEPSPLSVLQVPENPLLSTCLCVSMSSNQAEFFL
                     TVWIFAIIVRQSCVRTLVLSFRNPFSIMVQSNPILPCIRS"
     CDS             complement(4903..5469)
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="LNGHDIRDYRLSDLRGLMGYVPQDQFLFASSILDNVRFGNPDISF
                     DKVEEATKLAQVYDDIKDMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILDPDILILDD
                     SLSAVDAKTEHAIIDNLKHTRKDKTTIITAHRLSAVVHADLILVMQDGRIIERGRHEDL
                     LAQGGWYAKTYESQQLEMEGGEADA"
     CDS             complement(5466..6659)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 174.9; E-value:
                     4.7e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="LSFKESIIAKLWWFFKLEKRRYIVGILALSLVSVLNLIPPMVMGR
                     VIDAITSGKLTNQILLLNLVYLLLAALGMYYLRYVWRMYILATSYRLGQIMRSRLFEHF
                     TKMSPSFYQKYRTGDLMAHATNDINSLTRLAGGGVMSAVDASITALVTLITMFFSISWQ
                     MTLVAVLPLPFMAFATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQEA
                     ELQSFQETNKMTFKKNMHTMKYDSLFDPLVLLFVGSSYVLTLLVGAFMIQAGQITVGNL
                     VTFITYLDMLVWPLMAIGFLFNITQRGNVSYQRIENLLEQESDVQDPAHPLPSIENGCL
                     EYAIDRFAFEDEDTLRDIHFTLDKGKLLAWLGRLVQERPPLSSCSCGSTMLIKEPSI"
     CDS             complement(6723..7169)
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MKHLMMTVVTVLTLGVTMTMVKADTYQSGRDADIMRERGQVWNYS
                     EDKREPQLANYNTDGRYLSEATNFELYNFVREYKTSDEIRRIWSPKKDESVIHDKDSYS
                     MDGGNKVYNFDSFAYQLPESTDFGKLSYIGHFQLEDGTIYRYWK"
     CDS             complement(7271..7798)
                     /locus_tag="ctg38_10"
                     /transl_table=11
                     /translation="MFQLKTWVDKDGELTSKGRKLSRVLVCAYLLCLVLLCWTPQYGLV
                     EGVETPGIQHFGRVVVLLTPFNSLTNFYQLDSLKEIVFVLGQNVTNIFLLSPLILGLLA
                     LYPRFRSWTKVLLATFVMSLTIEVGQVILDLLIDANRVFELDDLWTNTLGGLVALGVYR
                     LLVKLIQTHFKE"
     CDS             complement(7800..8969)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_11"
                     /sec_met_domain="PF04055 (E-value: 2.6e-21, bitscore: 66.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVTTQAKPERRKRQKLEDMEGYKPSIYGLTRDELIDWAMEHGE
                     KKFRATQIWDWLYKKRVQSFEEMTNISKDFIAKLNENFCVNPLKQRIVQESKDGTVKYL
                     FELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLTAGEIVAQIML
                     VQKYFDDRGDGERVSHVVVMGIGEPFDNYDNVLRFLRTINNDNGLAIGARHITVSTSGL
                     APKIKEFANEGVQVNLAVSLHAPNNDLRSSIMRINRSFPLEKLFEAIEYYIQTTNRRVT
                     FEYIMLNEVNDHPENAQELADLTKKIRKLSYINLIPYNPVSEHDQYSRSTKERVAAFYD
                     VLKKNGVNCVVRQEHGTDIDAACGQLRSNTMKRDRQKAVAEASGKSEGK"
     CDS             complement(8973..9701)
                     /locus_tag="ctg38_12"
                     /transl_table=11
                     /translation="MRKEILPEMFNYNKYPGPDFVYVADLLKSDACQFTVLENHKDALD
                     ATRFGQRFSEIMLKYDYIVGDWSNDQLRLKGFYEDERPNTRKTDRISRLSEYLREYCAF
                     GCAYFILKNEEPQLIVFEEETEPRRKRRRSNNRRHSSQESRDRERNASQKNKGQKASAK
                     QKPDKSKRRDRDQEGPSFEKIKRRPKFKSRSEDGGRERKPNFKKSQKQAPKSKGQNTPS
                     KKQSQTKSDGQHFTIRKKGN"
     CDS             complement(9731..11155)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283:2`,3`-cyclic-nucleotide 2`-phosphodiesterase
                     (Score: 207.1; E-value: 8.4e-63)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_13"
                     /transl_table=11
                     /translation="MIVKFFYSKSATIGVMKDTIRILHINDLHSHFEQYPQLKRAVDDL
                     SQTDRELIKVDLGDNVDKSHPLSDATAGRFNVALMNELGIDYATIGNNEGIGLAKDELD
                     CLYEKAKFQPIIGNLKDEGRQPEWGKPYLIHKTKAGTKIAFLAYTFPYYITYAPNGWQV
                     LEPMARLEEDLARPEVRDADIIIVLSHLGVRYDEQIAETYPQVNLVIGSHTHHLFEEGK
                     LVNETYLAAADRYGYYLGCIDLTVENGQLIGCQIEAIPTKSYILDLDKEDEAFIKAMRE
                     EGHRRLAQKKVANLGRELDFDETCQLVLQAVCQETHSQLTLLNTGLIMKTLGPQVTMAD
                     LQEALPHQMRMARLVVTGQELKEICQEVFTKAELLKNQAIKGMGFRGKTFGEVITGNFA
                     YKNGNLLYNRRVVDSNEKFSLVLVDQYYFASYFPTIKEKEVTLLFPDLLRELVAKYLGK
                     MVPIGIRYRDIITASG"
     CDS             complement(11383..11613)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_14"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2e-10, bitscore:
                     31.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQIINNFNSLNSEDLSTVKGGACSFWGATAAVGVGAVGGAIKG
                     GIQTGTWQGAALKGIGYGIKDGITYGLICRY"
     CDS             complement(12166..12600)
                     /locus_tag="ctg38_15"
                     /transl_table=11
                     /translation="KHFKIDNLFELNKIEYGILSLPPFLSIILLLYKMPLPLSRVLIFD
                     SYLLLINIVIIVLYNYLSEKNYNIIKGKIAFDENSMTSEIIQQEEELAILRHDLKNIVS
                     SIDFYADSNDFGNIKAITREILGQEVFNRKIQDVYQLTLY"
ORIGIN
        1 atttgcctgt ttctttactt aataaacaaa agagtttcaa ttgggcattt tcttattatc
       61 ttattttgtc gcatagcata taccaaaata tgtaacagtc tatcctggaa attcttattc
      121 tactttaacg aagaaatatt ctatctttta ttatcttttt ttatatcacg aaagccctac
      181 ttacaatcaa agcttaaaat attcaatgct cttctcccca caactcttaa taatatcagt
      241 tttagagtaa tcattttctt tatatttcct ttgtttggaa tcagtgttga aacaataaaa
      301 gttaattatc ttatagctgt ctcatcatct ttcctaacta ttttactatc ctttctttta
      361 ataaaattat tcaaggaaag ctttggagtt atacaaaaag gacgattagc ccctctcata
      421 tcaaagagta ttattattgc tgatatcatt atgattgctt atacatttac ccagcaatat
      481 ctcgtctacc tcgaaaacac tactcataca tccactctga taatcaggaa gttaattgtg
      541 gttatttatc tagtcttttt ctttatcatg cttatcttct tagatagaaa tatccgagca
      601 acaatacaaa gtcagttgga ctttcaaaaa gatattcaac tatcgcatct tacgaattat
      661 aacaaacaga ttgaaaacct ctatcagtcg gttcgaagtt ttcgtcatga ttatgccaat
      721 attttaacaa cactcaaact tggtatcgat caaaatgata tggctattgt aaaagaagtc
      781 tacgactcag ttctaaaaga ttccgataag catttaaaat cgaaaacatt tgatttaact
      841 cgcttaataa acatagaaga taacactatc aaaagcctac ttgcagctaa gttcctagag
      901 gcagaagaaa ataacattga tatctcctta gatattcctg aaactatcaa actcgagggt
      961 atggagatgg tcgattttat tactgtaata tctatctttc tagacaatgc gatggaagca
     1021 tcgattcagt ctgacatacc aaaaatgcat attggctact tcaatcatgg taataagcaa
     1081 atctttattg tccaaaactc aacccaggaa gaatttattc ctatctcatc actttttgag
     1141 agaggtgtct ccagtaaagg ggatcatcgc ggtataggtt tggccaacgt taggaatata
     1201 ttagacaact atcaaaatat ttctttaaaa actgaaagta tgacttttgc atttacacag
     1261 gaacttaata tatcgaaaaa agcttgacta gtttcaagct ttttctgttg ctccatctta
     1321 ctacttatga aagtatcttc tagattacct acagaataat caagtgaaat catttattgt
     1381 ttaaaatagt ttctgacttg caagtaagct agaaaatcac agaggattaa caaaagcatt
     1441 aatacggcta gtactatacg gtctgtgata tcactgaatg taagtaatgt gtaaaactct
     1501 acacaaagca caagaaatga gatgacaaga aagacaatga aggactgccg tattgttaac
     1561 ggatttactg aatctggacg tttcttaagc aaacggtaga gcagtccatt aacaaaaatg
     1621 actactaaag ctagtgctcc gactgctaac caaatctctg gagaggtctt gcttttgtag
     1681 agagaaatac tggtacttat aaggaaaact gccagtacag cagtgacgac cctagaaaat
     1741 cgcaatactc ttgaactaat attctttaac ttcatgataa aacaattaag ctatgaataa
     1801 cctcagtcag tcttgtaaac tgaataagct attacattta actatattcc tttctgtatt
     1861 tcatatttcg tttatacatt gctatcttta gtaggcttga gaataagccc ttagcgatta
     1921 aattctactg gagatgtaat acaatagcgt cattagtact gatactttaa ataagcgaat
     1981 atacatatct ttgtttttct attacaaaga tatgcaatca aatataatat aatctccgct
     2041 atcattagca agaataattt tacttcggga acatcaaaaa taagcatttg caagcacctc
     2101 acgttcaaag gggccacaag ttacttttta aactgtgccc atttttttaa aagcagacta
     2161 taaagaagca aggttagccc aaacaagtta atggtatggt gaacagcatc caaacttcta
     2221 aatagattag caaggcccat tcctatgaga atggtagcca gtaaatacgg ttttgagttt
     2281 ttaaacatac ttttctcctt aaagtgtttt tagctatctg tgcacaagct atgaatttta
     2341 ttatagattg gaagccgata aaaaagtagt gacataaatg tcactacttg tctgatttta
     2401 tatccttgat aatcgtacac ataagaaaga gaaaaagaca taacccaata agatttaggc
     2461 attgaagtcc aaaactcagt ttttctccca agttatgtaa ggcaacaagg atgaagccca
     2521 tagacatcat tagagacact agacgttttt tagtcataag tacaaatacc tcttctttta
     2581 tatcgaagtt ttcaaccact attcacaagc tattcacaga ctagcaattg acaaggtatc
     2641 tcaattaaga tttcttttta atggaattgg tagatttgtg tttttcaagc aatgacataa
     2701 taggcttatc caaaaaagtc atcaaggcca tgcaaaccat ccctaaaata taacttttca
     2761 aatcaaacat aatccatcac caccagcatg ttgctccata accaacaccc cctacaatag
     2821 cacctccagc tgctcctgcg acagcacctt gccaagtacg tgttttgata cctaatcgta
     2881 aaccattacc aactcctgta gctactcctt gtttagcaaa acctccccag ctacatccac
     2941 caccttcaac gtttgcaagt gcctcgagat cgagtgtttc aaaagtgttc attgtttgtg
     3001 ttgtcattct aacaacctcc taaaatatta ttttttagct ttttctctca agctatggtt
     3061 ttattatagg gtgcaagcca acaaaaagta gtgacataaa tgtcaccact cgattttgat
     3121 ttttaagaaa tcttttcgaa tatagaatct atggtctaga ctagcttact ctccttccat
     3181 tgcacctgct tgtaggctgt acatcttatg ataggtacca ccgagggcta ggagttcctc
     3241 atggctaccg tgttcgatga tgcggccctt gtctaagaca tagatgcagt tggcatcttg
     3301 gattgtcgat aggcggtggg caatggcaat ggttgtgcgt ccttgacgca tttttgctag
     3361 agaattttgg acaatagcct ctgtctctga atcaatattg gctgtcgctt catctagaat
     3421 caaaatctta ggctggctag caacggtcct agcaaaggct agaagttggc gctgtccggt
     3481 tgaaaaactt gaacctcgtt cagaaactgg agcatcatat ccttctggaa gtttgtcgat
     3541 aaagtgattg gcatccacaa actcagcggc cgctttaatc tcttcatcag ttaactcctg
     3601 atacatggca atattggatt tgattgtacc atgatagaga aagggttcct gaaggacaag
     3661 accaatgttc ttacgcaact ctgtctgact ataatcgcga atatccacac cgtcaagaag
     3721 aactcggcct gattggaact catagaaacg cataaacacg ttgataatag aggattttcc
     3781 ggaacctgta gaaccgacaa aggcgatggt tcacctttac tgacagagaa ggaaatatta
     3841 tccaaaatct ggtgcttgcc atcataggag aaggagacat tttcaaagcg aatattcccc
     3901 tcagtaacct tggcatctgt atctctctgt tctggctcat aggtgcgctc gtcaatcaag
     3961 gcaaagaccc gaccggctga gaccatagaa gtttgcaagg ttgagaagtt ttgtgtcact
     4021 tcaatcaagg gatcaaaaag acggttaatg tactggataa aggcatacat ggtccccgct
     4081 gtgataccta gatagatacc acgatagcca aaataggcca tgagaacagc atagcccagg
     4141 agcttcagta agctcatggc tgggcgtaga aagagagagt ccagtgacat ggaacggcta
     4201 gcataaatca ggtgttcctc attaatagca tcaaactctt ttttgaggcg tttctcttgg
     4261 ttgaaggcct gaatgatgcg aatcccttcg atactctctg acagtttggc atttatatct
     4321 gaaagcaagg ctctggtctt ttcaatgata accactgatt tttttcggta aaggttaacc
     4381 aaaagaacaa tcaaaggaag aaagagtaca ataagcccgg tcagacgaat gtccaacatc
     4441 atcatagtgt aaagggtagt gacaaagata aatatagccg aaataaagct agacagaatc
     4501 cctgagaaca tctcactaat agtctctgta tcattggtca agcgagaaac gatagagcct
     4561 gcgggagtct tgtcaaagta agacataccc agtttttcca tattggcaaa ggcatctcgg
     4621 cgaatatccc tgacaatact gtaggacaca cgcgcaaaaa agagatttcc caaatactga
     4681 actagtgtct gcaaaagata aagaccatag taaccaatca gaattaagct tgctgcctga
     4741 ttcatatcat gaagatagtg gtcgataaaa taagaggcca caaggggaat aatactcttg
     4801 ataaccgttg tggacaagag gaaggctaaa gctagaaagg tcaagaattt gtaaggcttg
     4861 agataggtca agagacgctt aaacacagac cattggtttt gattaggcat cggcttctcc
     4921 tccttccatt tctaactgtt gagactcata ggtcttggca taccaaccac cctgagctag
     4981 caaatcctca tgacggccac gttcaatgat acgaccatcc tgcatgacta agataaggtc
     5041 agcgtgcacc accgcactca gacgatgggc ggtaatgata gtcgtcttgt ccttgcgggt
     5101 atgtttgaga ttgtcaataa tagcatgttc tgtcttggca tcaaccgcag atagggagtc
     5161 gtccaaaatc aaaatgtctg gatccaaaat catggcccga ctcatggcca gacgttgttt
     5221 ttgaccgcct gataggctga cacccttttc accaatgatt gtttcaaagc cttcaggcat
     5281 gtccttgatg tcatcataaa cttgagccaa cttagtcgct tcttctacct tgtcaaagga
     5341 gatgtccgga ttaccaaagc ggacattgtc taaaatggaa ctggcaaaga gaaactggtc
     5401 ttgaggaaca tagcccatca agccacgcaa gtctgatagg cgatagtctc ggatgtcatg
     5461 cccattcaaa tagatggctc cttgattaac atcgtgctcc cgcaagagca acttgacaag
     5521 ggcggtcttt cctgaaccag tctgcccaac caagccaaga gtttgccctt gtccaaggtg
     5581 aaatgaatat ctctcaaagt atcctcatcc tcaaaagcaa agcggtcaat cgcatattct
     5641 aagcaaccat tttcaatact tgggagaggg tgcgcaggat cttgaacatc tgattcctgc
     5701 tccagaagat tttcaatacg ttggtaggac acatttcctc tctgtgtgat attaaagagg
     5761 aagccaatgg ccattagggg ccaaaccagc atgtccaaat aggtaatgaa ggttaccaaa
     5821 tttccgaccg ttatctgacc agcctgaatc ataaaggcac cgacaagaag ggtcaaaaca
     5881 taagatgagc caacaaagag taagaccaaa ggatcaaaaa ggctgtcata cttcatggta
     5941 tgcatattct ttttaaaggt catcttattg gtctcttgga aggactgaag ctcagcctcc
     6001 tgatagccaa aagacttggt taccttgata cctgataccg actcttgaac cttattatta
     6061 agttctgaaa aggctgcctg ggattctcca aaagctttat gggtcttgcg gcccaaacga
     6121 ctagtcgcaa aagccatgaa aggtaggggt aagacagcca ctagtgtcat ctgccaggaa
     6181 atgctgaaaa acatagtgat tagggttacc aaggctgtaa tagaggcatc cacggctgac
     6241 atgacacccc caccagccaa gcgggttaaa gagttgatat cattggttgc atgggccatg
     6301 agatccccag ttcggtactt ttgataaaaa gaaggcgaca tcttggtaaa atgctcaaat
     6361 aggcgtgaac gcataatctg gcctaagcgg taagaagtcg ccaagatata catgcgccaa
     6421 acatagcgca aatagtacat ccccagagct gccaaaagca aataaacgag attcagaagc
     6481 aagatctgat tggtcaattt tcccgatgtg atagcatcaa tgacccgccc cataaccata
     6541 ggaggaatca gattgagaac cgaaaccaga ctcagtgcca aaatcccaac aatataccgg
     6601 cgtttttcta acttgaaaaa ccaccaaagt tttgcaatga ttgattcttt aaaagacaag
     6661 ttactcctcc tatccttaca aatggttaat aatagacctc gtataagtct cgtatgataa
     6721 ggttacttcc aatagcgata gattgtgcca tcttctaact gaaagtgacc aatataagat
     6781 aacttcccaa aatcagtaga ctctggtaat tgataagcaa aggaatcaaa attatatacc
     6841 ttgttcccac catccataga gtaactatcc ttatcatgga taactgattc atctttctta
     6901 gggctccaaa tgcgtctgat ttcatcagat gtcttatact ctctgacaaa attgtacaat
     6961 tcaaagttag ttgcctcact gagatagcga ccatcggtgt tgtagttggc taattgaggc
     7021 tctctcttat cctcagaata attccaaacc tgtcctcttt ctcgcatgat atcggcatca
     7081 cgaccacttt gataagtatc tgccttaacc atcgtcattg ttactcctaa cgttaatacg
     7141 gtgactactg tcatcattaa gtgtttcatt atttctccaa acgtgtttat tcatttttcc
     7201 ctcttttgaa tgtgttgtat ttgtatgata gaaaataagt gaaacctggg acacatagct
     7261 cccaggtttt ttactcttta aaatgcgttt gaatcagttt tacaagaagg cggtaaacac
     7321 ctagtgccac caaaccaccc aaagtattgg tccataaatc atctaactca aagacacgat
     7381 tagcatcaat gagaaggtct agaataactt gtccaacctc aatcgtcaaa gacatgacaa
     7441 aggtcgctaa aaggaccttt gtccaagacc tgaatcttgg gtacaaggct aaaagcccta
     7501 aaatcagcgg actcagcaag aaaatgttgg tcacattttg cccaagcaca aagacaatct
     7561 ctttaagact atccagctga taaaagttgg tcaaactatt gaatggggtt aataggacca
     7621 cgacacgacc aaaatgttga ataccagggg tttcaacacc ttcaactagc ccgtactggg
     7681 gtgtccaaca taggagcact aaacaaagga gataagcaca gaccaaaact cggcttagct
     7741 ttcttccttt tgatgttagt tctccatcct tatctaccca agtcttaagc tgaaacatct
     7801 tacttacctt ctgatttacc agaagcttct gctactgcct tttgacggtc acgtttcata
     7861 gtgtttgaac gcaattgtcc acaagctgcg tcgatatctg taccgtgctc ttgacgaacc
     7921 acgcagttga ctccattttt cttgagcaca tcgtagaagg ccgccacacg ttctttcgtt
     7981 gaacggctat attggtcgtg ctctgatact ggattatatg gaatcaagtt gatgtatgac
     8041 aacttacgga ttttcttagt caaatcagcc aactcttgag cattttcagg atggtcattg
     8101 acctcattaa gcatgatata ctcaaaagtt acacgacggt tggttgtctg gatgtaatac
     8161 tcgatagctt caaagagttt ttcaagtggg aacgagcggt tgatacgcat gatgcttgaa
     8221 cgaaggtcat tgttaggcgc gtgaagtgat acggcaaggt taacttgaac accttcgtta
     8281 gcaaattcct taatttttgg tgccaaacca gatgttgaca cggtgatgtg acgcgctcca
     8341 atggcaagac cattgtcatt gttaatggta cgcaagaagc gaagcacatt gtcatagtta
     8401 tcaaatggct caccgatacc cataacaacc acgtggctga cacgttcacc gtcgccacga
     8461 tcgtcaaagt atttttgtac caacatgatt tgcgccacaa tctcaccagc agtcaagtca
     8521 cgttgtttct taatcaaacc actggcacag aaagtacaac cgatgttaca tccaacctgg
     8581 gttgtcacac agacagacaa accatagtgt tgacgcatca aaaccgtctc aatcaacata
     8641 ccatctggca attcaaaaag atatttaacg gtaccatctt tagattcttg aacgatacgt
     8701 tgtttcaatg ggttcacaca gaaattctca ttcaatttag caatgaaatc cttagaaatg
     8761 ttggtcattt cttcgaaaga ttgcacacgc ttcttgtaga gccaatccca aatttgagta
     8821 gcacggaatt tcttttcacc gtgttccata gcccaatcaa tcaactcgtc acgagtaaga
     8881 ccataaatag aaggtttgta gccttccata tcctctaact tctgacgttt acggcgttct
     8941 ggttttgctt gtgttgttac ttctgacata gtttaatttc ctttttttct gattgtgaaa
     9001 tgctgaccat ctgacttggt ctggctttgt ttcttcgatg gggtgttttg acctttagat
     9061 tttggagctt gcttctgact cttcttgaag ttaggcttac gctcacgacc accatcctcg
     9121 gatctagatt tgaacttagg acgacgcttg attttctcaa agcttgggcc ctcttgatcc
     9181 ctatctcttc gtttggactt gtctggcttt tgcttagcag aagctttttg ccccttattc
     9241 ttttgagaag cattgcgctc tctatctcta gattcctgag aagaatgacg acgattatta
     9301 gaacgacggc gcttgcgacg aggctccgtc tcctcttcaa agacgattaa ctgcggctct
     9361 tcatttttca aaataaagta ggcacagcca aaggcacagt attcacgcaa atactccgat
     9421 aatcggctaa tgcggtctgt cttacgcgta ttagggcgct cgtcctcgta aaatccctta
     9481 agacgaagct gatcattaga ccagtcccca acgatataat catacttgag catgatttca
     9541 gaaaaacgtt gcccaaagcg ggtagcgtct aaagcatcct tgtgattttc aagaactgta
     9601 aactgacagg catctgattt cagaagatca gccacataca caaagtctgg ccctggatat
     9661 ttattataat taaacatttc tggcaagatt tctttacgca tgtgccatcc tttctgctct
     9721 ctcttatttt ctatcctgat gctgtaataa tgtctctata tcttatccca attggcacca
     9781 tttttcctaa atacttggcc acaagttccc ttaacaaatc tggaaaaaga agagtaactt
     9841 ccttttcctt aattgtaggg aagtaagaag caaagtagta ctggtccaca aggaccaaac
     9901 taaacttctc attggaatct acaacccttc tattatacaa caaattaccg tttttgtaag
     9961 caaaattccc cgtgattact tcaccaaatg tcttccctct aaatcccata cctttaatag
    10021 cttgattttt aaggagttca gccttagtaa aaacttcctg acagatttct ttgagttctt
    10081 gtcctgtcac gactagacgt gccatccgca tctggtgagg aagggcttct tgcaggtctg
    10141 ccatggtcac ttgaggacct agtgttttca tgataagtcc agtatttaaa agcgttaact
    10201 gactatgagt ctcctgacaa acagcctgta aaaccaattg acaggtctca tcaaaatcta
    10261 gttctcgacc tagattagct acttttttct gagctaaacg acgatggcct tcctcacgca
    10321 tagccttgat aaaggcttcg tcctccttgt ctaaatccaa gatgtaggac ttggtgggga
    10381 tagcctcaat ctgacatcct atcaattgcc cattttccac agtaaggtca atacagccaa
    10441 gataataacc atatctgtca gcagctgcca aataggtttc attgactaat ttgccctctt
    10501 caaaaaggtg atgcgtgtgg ctcccaatga caaggtttac ctgtggataa gtctctgcaa
    10561 tctgctcatc ataacgtaca cctagatggc taagaacgat gattatatct gcatccctta
    10621 cctcaggacg agccaaatcc tcttccaacc tagccatagg ctctaacacc tgccaaccgt
    10681 tgggagcata ggtaatgtaa tatgggaagg tgtaggccaa aaaagcaatt tttgtacctg
    10741 ccttagtttt gtggataaga tagggcttgc cccattcagg ttgtctcccc tcatccttga
    10801 gatttcctat gatcggctga aacttagcct tctcataaag acagtctagc tcatccttgg
    10861 ccagaccaat cccctcatta tttccaatag tcgcatagtc tatccccaac tcattcatca
    10921 gggccacatt aaaacgccca gcggtcgcat cagacaaggg atgggactta tccacattgt
    10981 ccccaagatc taccttgatc aactctctat ctgtctgact caaatcatcc acagctcgct
    11041 tgagttgtgg atactgttca aaatgagagt gtaaatcatt gatatgaaga attcgaatcg
    11101 tgtctttcat gactcctatt gtagcacttt tgctataaaa aaacttgaca atcattctgc
    11161 caagttttta catgctattt ttcaaacagg aacgtattcc tagttaactt tctttttaac
    11221 atattcttct gcgagatgat agacgtcatc tgctagggat atactgacat agatgcacac
    11281 aattgagaaa atttctcctc taaagtgttg ccaagcaaag aatataagcc cataaattag
    11341 gagagcaagt actattggcc aaaaaattga ctcagtaatc gcctaataac gacaaataag
    11401 tccataagta atcccatctt taataccata accaataccc tttaaggctg caccttgcca
    11461 agtacctgtt tgaataccac ctttaatggc tcctccaaca gccccgacgc ctacggcagc
    11521 tgtagctccc caaaaactac atgctccacc cttaacagta gaaagatctt cggaattaag
    11581 tgagttaaaa ttgttaatga tttgtgttgt cattaaaaca acctccttta aaatattttt
    11641 tagccttttc tcaaaagcta tgattgtatt atagatagaa agccaacaaa aaagtagtga
    11701 cataaatgtc actacttgat tttgagagtt gattcaactt agaccttagg acttccaaat
    11761 tattttattt ttaaaggaat aacaactagt accacaaatt gatttgactg tatattaata
    11821 ttcaaatgtc ctttcagttt catgattcta tcataactac tttttattcc tagaccacgt
    11881 ctattaggta attttataga tttcattccg ttgtaattga tatctatttc agaagtaagt
    11941 ataggattcg ccactttaaa gactagttta ttattcttaa aacgtaatac tatttcgatt
    12001 ggattcgtta atccattacg ttcaatctcc tctattgcat tgtcgataat atttccgaga
    12061 atagcgcaga atctatagca atcgaactta tatctaagtt ataggggatt tgtaaatcta
    12121 gatgaaactg gactccatct tttttcattt tagatatttt ttgatttaat atagcgtcaa
    12181 ttggtataca tcctgtatct tgcgattaaa aacctcctgt cccagtatct ctcgagttat
    12241 tgctttgatg tttccaaaat cattactatc tgcataaaaa tctattgagg aaacaatatt
    12301 ttttaaatca tgtctgagaa ttgctagttc ttcttcttgt tgaataattt cactagtcat
    12361 gctattttca tcaaaagcaa ttttgccttt gataatatta taattttttt cactcaaata
    12421 attgtaaagc acaattataa caatgtttat caataataaa taactatcaa atatcaaaac
    12481 tcgacttaaa ggtagtggca tcttatataa cagtaaaata atagacaaaa atggaggcaa
    12541 cgataagata ccgtattcta ttttgttcag ctcaaataga ttatctattt taaagtgttt
    12601 ta
//
