Probiotic potential risk score
| ARGs (CARD) | VFs (VFDB) | PGs (PHI-base) | PPRS |
|---|---|---|---|
| 1 | 29 | 27 | 39.64 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| ARO accession | ARO name | Identity | Coverage | CARD name | Accession no. |
|---|---|---|---|---|---|
| ARO:3000192 | tet(S) | 99.84 | 100.78 | tet(S) | L09756.1 |
RGI v6.0.0 (Database: CARD Variants v4.0.0, Jul. 2022 release)
ResFinder
| Resistance gene | Identity | Coverage | Phenotype | Accession no. |
|---|---|---|---|---|
| tet(S) | 100.00 | 100.00 | Tetracycline resistance | L09756 |
ResFinder v4.0 (Database: resfinder_db, May 2022 release)
AMRFinderPlus
| Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|
| tet(S) | tetracycline resistance ribosomal protection protein Tet(S) | EXACTX | 100.00 | 100.00 | WP_000691722.1 |
AMRFinderPlus v3.10.42 (Database: Oct. 2022 release)
Virulence factors
Virulence Factor Database (VFDB)
BLASTN v2.8.1+ (Database: VFDB, Jun. 2022 release)
VirulenceFinder
| Database | Virulence factor | Identity | Coverage | Protein function | Accession no. |
|---|---|---|---|---|---|
| No hit found | |||||
VirulenceFinder v2.0.3 (Database: virulencefinder_db, Dec. 2022 release)
Pathogenic genes
PHI-base
| Protein ID | Gene name | Identity | Coverage | e-value | Function | Gene ID |
|---|---|---|---|---|---|---|
| Q1JLQ2 | MntE | 94.69 | 99.44 | 0.0 | Manganese Homeostasis | ABF32167 |
| P67331 | spr0084 | 92.88 | 98.18 | 0.0 | pathogenitcity related | AAK98888 |
| Q97S31 | metE | 91.99 | 99.87 | 0.0 | Methionine biosynthesis enzymes | AAK74738 |
| Q1J943 | prsA2 | 90.62 | 98.46 | 0.0 | Ribose-phosphate pyrophosphokinase | ABF36968 |
| Q8DPC2 | potA | 89.58 | 99.48 | 0.0 | ABC transporter ATP-binding protein - spermidine/putrescine transport | AAL00050 |
| Q8DYL6 | uvrB | 89.14 | 99.85 | 0.0 | Excinuclease ABC, B subunit | AE014259_2 |
| P0C0B9 | bglB | 88.89 | 99.33 | 0.0 | Putative phospho--glucosidase | AAK33487 |
| Q99Z66 | ptsI | 87.87 | 99.83 | 0.0 | Phosphoenolpyruvate-protein phosphotransferase | AAK34199 |
| D5AF41 | IMPDH | 87.63 | 99.80 | 0.0 | Inosine-5'-monophosphate dehydrogenase | ADE32434 |
| Q97S30 | metF | 86.71 | 98.96 | 0.0 | Methionine biosynthesis enzymes | AAK74739 |
| A4VYE0 | gidA | 85.74 | 98.75 | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | ABP91129 |
| P0A452 | recA | 84.67 | 98.46 | 0.0 | DNA recombination and repair | AAL00560 |
| B5TQV9 | PGM | 83.89 | 99.48 | 0.0 | phosphoglucomutase | ACH87041 |
| Q97RW0 | SP_0676 | 82.45 | 93.50 | 0.0 | Transcription facot | AAK74821 |
| A4VY17 | pdh | 82.20 | 99.41 | 0.0 | Pyruvate dehydrogenase | ABP91006 |
| A4VWD1 | mnmE | 81.80 | 99.34 | 0.0 | Central tRNA-modifying GTPase | ABP90420 |
| Q1JJJ3 | PepO | 80.19 | 99.84 | 0.0 | Endopeptidase | ABF32980 |
| Q93MY4 | covR | 85.53 | 99.58 | 3.10e-151 | Responder protein | AAK71319 |
| Q9S1K2 | rr01 | 83.93 | 99.12 | 3.24e-143 | Response regulator | CAB54566 |
| P0A4H7 | CiaR | 87.44 | 99.11 | 3.42e-143 | Two-component response regulator | AAK74935 |
| B3VA60 | CovR | 81.22 | 99.56 | 1.18e-136 | serves to repress GAS virulence factor-encoding genes | ACE75886 |
| U2W9V3 | SpxA2 | 90.91 | 99.25 | 3.52e-88 | Transcriptional regulator | ERL21461 |
| Q8DQV4 | spr0479 | 84.38 | 97.96 | 5.33e-58 | essential gene | AAK99283 |
| Q8DP67 | spr1327 | 95.29 | 98.84 | 4.34e-55 | essential gene | AAL00131 |
| Q8DRE1 | spr0177 | 84.27 | 87.25 | 2.43e-51 | essential gene | AAK98981 |
| Q8CZ89 | spr0175 | 84.09 | 98.88 | 4.47e-51 | pathogenitcity related | AAK98979 |
| Q04M32 | ilvC (SPD_0406) | 96.47 | 99.71 | 0.0 | Ketol-acid reductoisomerase (NADP(+)) | ABJ55451 |
BLASTP v2.8.1+ (Database: PHI-base v4.14, Nov. 2022 release)
Plasmid
PlasmidFinder
| Plasmid | Identity | Query / Template | Accession no. |
|---|---|---|---|
| No hit found | |||
PlasmidFinder 2.0.1 (Database: plasmidfinder_db, Jan. 2023 release)
Prophage
Phigaro
| Scaffold | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| CM002372.1 | 622294 | 662880 | False | Siphoviridae | VOG7656, VOG4602, VOG6127, VOG3622, VOG1564, VOG9469, VOG3478, VOG8482, VOG0651, VOG0321, VOG0322, VOG4548, VOG0226, VOG4632, VOG4606, VOG3302, VOG0327, VOG6414, VOG0656, VOG4571, VOG4571, VOG0152, VOG11003, VOG0152, VOG6495, VOG0657, VOG0044, VOG0658, VOG0198, VOG0796, VOG4544, VOG0720, VOG4564, VOG4555, VOG3434, VOG1887, VOG3435, VOG4713, VOG0723, VOG5660, VOG0724, VOG0799, VOG0725, VOG0800, VOG3636, VOG4605, VOG4599, VOG0647, VOG4782, VOG3298, VOG3424, VOG0054, VOG4649 |
Phigaro v2.3.0 (Database: Aug. 2017 release)