Probiotic potential risk score
| ARGs (CARD) | VFs (VFDB) | PGs (PHI-base) | PPRS |
|---|---|---|---|
| 0 | 21 | 27 | 34.21 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| ARO accession | ARO name | Identity | Coverage | CARD name | Accession no. |
|---|---|---|---|---|---|
| No hit found | |||||
RGI v6.0.0 (Database: CARD Variants v4.0.0, Jul. 2022 release)
ResFinder
| Resistance gene | Identity | Coverage | Phenotype | Accession no. |
|---|---|---|---|---|
| No hit found | ||||
ResFinder v4.0 (Database: resfinder_db, May 2022 release)
AMRFinderPlus
| Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|
| No hit found | |||||
AMRFinderPlus v3.10.42 (Database: Oct. 2022 release)
Virulence factors
Virulence Factor Database (VFDB)
BLASTN v2.8.1+ (Database: VFDB, Jun. 2022 release)
VirulenceFinder
| Database | Virulence factor | Identity | Coverage | Protein function | Accession no. |
|---|---|---|---|---|---|
| No hit found | |||||
VirulenceFinder v2.0.3 (Database: virulencefinder_db, Dec. 2022 release)
Pathogenic genes
PHI-base
| Protein ID | Gene name | Identity | Coverage | e-value | Function | Gene ID |
|---|---|---|---|---|---|---|
| Q1JLQ2 | MntE | 94.41 | 99.44 | 0.0 | Manganese Homeostasis | ABF32167 |
| P67331 | spr0084 | 91.95 | 98.18 | 0.0 | pathogenitcity related | AAK98888 |
| Q97S31 | metE | 91.86 | 99.87 | 0.0 | Methionine biosynthesis enzymes | AAK74738 |
| Q1J943 | prsA2 | 90.62 | 98.46 | 0.0 | Ribose-phosphate pyrophosphokinase | ABF36968 |
| Q8DPC2 | potA | 89.32 | 99.48 | 0.0 | ABC transporter ATP-binding protein - spermidine/putrescine transport | AAL00050 |
| Q8DYL6 | uvrB | 89.14 | 99.85 | 0.0 | Excinuclease ABC, B subunit | AE014259_2 |
| P0C0B9 | bglB | 88.89 | 99.33 | 0.0 | Putative phospho--glucosidase | AAK33487 |
| Q99Z66 | ptsI | 87.87 | 99.83 | 0.0 | Phosphoenolpyruvate-protein phosphotransferase | AAK34199 |
| D5AF41 | IMPDH | 87.22 | 99.80 | 0.0 | Inosine-5'-monophosphate dehydrogenase | ADE32434 |
| A4VWH9 | Eno | 85.75 | 99.54 | 0.0 | Enolase | ABP90468 |
| Q97S30 | metF | 85.66 | 98.96 | 0.0 | Methionine biosynthesis enzymes | AAK74739 |
| A4VYE0 | gidA | 85.26 | 98.75 | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | ABP91129 |
| P0A452 | recA | 85.19 | 98.46 | 0.0 | DNA recombination and repair | AAL00560 |
| B5TQV9 | PGM | 83.89 | 99.48 | 0.0 | phosphoglucomutase | ACH87041 |
| Q97RW0 | SP_0676 | 82.45 | 93.50 | 0.0 | Transcription facot | AAK74821 |
| A4VY17 | pdh | 82.20 | 99.41 | 0.0 | Pyruvate dehydrogenase | ABP91006 |
| A4VWD1 | mnmE | 81.36 | 99.34 | 0.0 | Central tRNA-modifying GTPase | ABP90420 |
| Q93MY4 | covR | 84.25 | 99.58 | 1.49e-148 | Responder protein | AAK71319 |
| Q9S1K2 | rr01 | 84.82 | 99.12 | 1.68e-145 | Response regulator | CAB54566 |
| P0A4H7 | CiaR | 87.00 | 99.11 | 1.53e-143 | Two-component response regulator | AAK74935 |
| B3VA60 | CovR | 81.22 | 99.56 | 3.51e-129 | serves to repress GAS virulence factor-encoding genes | ACE75886 |
| U2W9V3 | SpxA2 | 89.39 | 99.25 | 2.83e-86 | Transcriptional regulator | ERL21461 |
| Q8DQV4 | spr0479 | 85.42 | 97.96 | 2.10e-57 | essential gene | AAK99283 |
| Q8DP67 | spr1327 | 95.29 | 98.84 | 3.98e-55 | essential gene | AAL00131 |
| Q8CZ89 | spr0175 | 84.09 | 98.88 | 4.09e-51 | pathogenitcity related | AAK98979 |
| Q8DRE1 | spr0177 | 82.02 | 87.25 | 8.22e-50 | essential gene | AAK98981 |
| Q04M32 | ilvC (SPD_0406) | 96.47 | 99.71 | 0.0 | Ketol-acid reductoisomerase (NADP(+)) | ABJ55451 |
BLASTP v2.8.1+ (Database: PHI-base v4.14, Nov. 2022 release)
Plasmid
PlasmidFinder
| Plasmid | Identity | Query / Template | Accession no. |
|---|---|---|---|
| rep37 | 90.93 | 948 / 945 | HM050421 |
PlasmidFinder 2.0.1 (Database: plasmidfinder_db, Jan. 2023 release)
Prophage
Phigaro
| Scaffold | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.3.0 (Database: Aug. 2017 release)