ORF_ID e_value Gene_name EC_number CAZy COGs Description
NIOIMGPL_00002 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NIOIMGPL_00003 8.1e-123 gntR K FCD
NIOIMGPL_00004 2.4e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIOIMGPL_00005 0.0 3.2.1.55 GH51 G arabinose metabolic process
NIOIMGPL_00008 0.0 G Glycosyl hydrolase family 20, domain 2
NIOIMGPL_00009 2.2e-188 K helix_turn _helix lactose operon repressor
NIOIMGPL_00010 7.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIOIMGPL_00011 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
NIOIMGPL_00012 1.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
NIOIMGPL_00013 3.5e-137 S Protein of unknown function DUF45
NIOIMGPL_00014 1.9e-83 dps P Belongs to the Dps family
NIOIMGPL_00015 5.8e-189 yddG EG EamA-like transporter family
NIOIMGPL_00016 1.2e-241 ytfL P Transporter associated domain
NIOIMGPL_00017 7.2e-95 K helix_turn _helix lactose operon repressor
NIOIMGPL_00018 2.2e-117 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NIOIMGPL_00019 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
NIOIMGPL_00020 0.0 trxB1 1.8.1.9 C Thioredoxin domain
NIOIMGPL_00021 4.2e-147 yhjX EGP Major facilitator Superfamily
NIOIMGPL_00022 1e-81 yhjX EGP Major facilitator Superfamily
NIOIMGPL_00023 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NIOIMGPL_00024 0.0 yjjP S Threonine/Serine exporter, ThrE
NIOIMGPL_00025 6.5e-180 S Amidohydrolase family
NIOIMGPL_00026 1.1e-194 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NIOIMGPL_00027 9.4e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIOIMGPL_00028 6.2e-45 S Protein of unknown function (DUF3073)
NIOIMGPL_00029 1.5e-79 T protein histidine kinase activity
NIOIMGPL_00030 1e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIOIMGPL_00031 3.5e-29 I transferase activity, transferring acyl groups other than amino-acyl groups
NIOIMGPL_00032 0.0 vpr M PA domain
NIOIMGPL_00033 4.7e-123 yplQ S Haemolysin-III related
NIOIMGPL_00034 2.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
NIOIMGPL_00035 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
NIOIMGPL_00036 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIOIMGPL_00037 5.1e-278 S Calcineurin-like phosphoesterase
NIOIMGPL_00038 4.5e-285 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
NIOIMGPL_00039 1.7e-116
NIOIMGPL_00040 1.7e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIOIMGPL_00042 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
NIOIMGPL_00043 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NIOIMGPL_00044 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIOIMGPL_00045 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
NIOIMGPL_00046 6.4e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
NIOIMGPL_00047 6.9e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
NIOIMGPL_00048 1.9e-41 S Protein of unknown function (DUF4244)
NIOIMGPL_00049 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
NIOIMGPL_00050 9.2e-14 gspF NU Type II secretion system (T2SS), protein F
NIOIMGPL_00051 5.1e-122 U Type ii secretion system
NIOIMGPL_00052 2.8e-190 cpaF U Type II IV secretion system protein
NIOIMGPL_00053 2.6e-152 cpaE D bacterial-type flagellum organization
NIOIMGPL_00055 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NIOIMGPL_00056 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
NIOIMGPL_00057 8.6e-91
NIOIMGPL_00058 5.7e-29 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NIOIMGPL_00059 5.9e-131 S Glycosyltransferase, group 2 family protein
NIOIMGPL_00060 0.0 S LPXTG-motif cell wall anchor domain protein
NIOIMGPL_00061 6.7e-152 S Protein of unknown function (DUF3801)
NIOIMGPL_00062 1.4e-166
NIOIMGPL_00063 0.0 S Glycosyl transferase, family 2
NIOIMGPL_00064 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NIOIMGPL_00065 6.6e-268 K Cell envelope-related transcriptional attenuator domain
NIOIMGPL_00066 0.0 D FtsK/SpoIIIE family
NIOIMGPL_00067 5.4e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NIOIMGPL_00068 9.5e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIOIMGPL_00069 9.8e-142 yplQ S Haemolysin-III related
NIOIMGPL_00070 2.3e-107
NIOIMGPL_00073 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIOIMGPL_00074 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
NIOIMGPL_00075 8.8e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
NIOIMGPL_00076 1.6e-97
NIOIMGPL_00078 1e-184 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
NIOIMGPL_00079 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
NIOIMGPL_00080 3.2e-101 divIC D Septum formation initiator
NIOIMGPL_00081 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIOIMGPL_00082 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
NIOIMGPL_00083 9e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
NIOIMGPL_00084 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIOIMGPL_00085 4.9e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIOIMGPL_00086 1.1e-95 2.3.1.183 M Acetyltransferase (GNAT) domain
NIOIMGPL_00087 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
NIOIMGPL_00088 2.3e-150 GM ABC-2 type transporter
NIOIMGPL_00089 1.9e-197 GM GDP-mannose 4,6 dehydratase
NIOIMGPL_00090 1.8e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NIOIMGPL_00092 1.2e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
NIOIMGPL_00093 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIOIMGPL_00094 2.9e-177 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIOIMGPL_00095 0.0 S Uncharacterised protein family (UPF0182)
NIOIMGPL_00096 7.4e-231 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
NIOIMGPL_00097 4.5e-197
NIOIMGPL_00098 4.3e-152 ytrE V ATPases associated with a variety of cellular activities
NIOIMGPL_00099 2.4e-190 V N-Acetylmuramoyl-L-alanine amidase
NIOIMGPL_00100 1.1e-95 argE E Peptidase dimerisation domain
NIOIMGPL_00101 8.8e-68 argE E Peptidase dimerisation domain
NIOIMGPL_00102 2.7e-103 S Protein of unknown function (DUF3043)
NIOIMGPL_00103 3.5e-194 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIOIMGPL_00104 1.4e-101 S Domain of unknown function (DUF4191)
NIOIMGPL_00105 3.1e-286 glnA 6.3.1.2 E glutamine synthetase
NIOIMGPL_00106 4.7e-10
NIOIMGPL_00108 5.5e-33 traSA D DNA segregation ATPase FtsK SpoIIIE
NIOIMGPL_00112 5.2e-79 S GIY-YIG catalytic domain
NIOIMGPL_00113 7.7e-29 3.1.21.4 L Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
NIOIMGPL_00114 6.3e-115 L DNA restriction-modification system
NIOIMGPL_00115 2e-86 int L Phage integrase, N-terminal SAM-like domain
NIOIMGPL_00116 4.4e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NIOIMGPL_00117 1.2e-209 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NIOIMGPL_00118 5.5e-30 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIOIMGPL_00119 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIOIMGPL_00120 0.0 S Tetratricopeptide repeat
NIOIMGPL_00121 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIOIMGPL_00122 4.9e-75 2.8.2.22 S Arylsulfotransferase Ig-like domain
NIOIMGPL_00123 4.9e-137 bioM P ATPases associated with a variety of cellular activities
NIOIMGPL_00124 7.8e-213 E Aminotransferase class I and II
NIOIMGPL_00125 1.7e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
NIOIMGPL_00127 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIOIMGPL_00128 1.7e-14 ecfA GP ABC transporter, ATP-binding protein
NIOIMGPL_00129 1.8e-40 ecfA GP ABC transporter, ATP-binding protein
NIOIMGPL_00130 0.0 ecfA GP ABC transporter, ATP-binding protein
NIOIMGPL_00131 5.2e-257 EGP Major facilitator Superfamily
NIOIMGPL_00133 2.2e-174 rarA L Recombination factor protein RarA
NIOIMGPL_00134 4.1e-27 rarA L Recombination factor protein RarA
NIOIMGPL_00135 0.0 L DEAD DEAH box helicase
NIOIMGPL_00136 1.9e-192 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
NIOIMGPL_00137 2.3e-78 gluD E Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00138 6.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00139 9.5e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
NIOIMGPL_00140 1.5e-144 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
NIOIMGPL_00141 4.9e-84 S Aminoacyl-tRNA editing domain
NIOIMGPL_00142 5.3e-84 K helix_turn_helix, Lux Regulon
NIOIMGPL_00143 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NIOIMGPL_00144 2.7e-263 hisS 6.1.1.21 J Histidyl-tRNA synthetase
NIOIMGPL_00145 6.6e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
NIOIMGPL_00149 0.0 clpC O ATPase family associated with various cellular activities (AAA)
NIOIMGPL_00150 3e-184 uspA T Belongs to the universal stress protein A family
NIOIMGPL_00151 1.1e-192 S Protein of unknown function (DUF3027)
NIOIMGPL_00152 1e-66 cspB K 'Cold-shock' DNA-binding domain
NIOIMGPL_00153 2.9e-238 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NIOIMGPL_00154 1.4e-133 KT Response regulator receiver domain protein
NIOIMGPL_00155 2.8e-173
NIOIMGPL_00156 1.7e-10 S Proteins of 100 residues with WXG
NIOIMGPL_00157 2.3e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIOIMGPL_00158 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
NIOIMGPL_00159 3.4e-71 S LytR cell envelope-related transcriptional attenuator
NIOIMGPL_00160 8e-145 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIOIMGPL_00161 1e-196 moxR S ATPase family associated with various cellular activities (AAA)
NIOIMGPL_00162 8.6e-138 S Protein of unknown function DUF58
NIOIMGPL_00163 1.3e-140 S von Willebrand factor (vWF) type A domain
NIOIMGPL_00164 3.6e-148 S von Willebrand factor (vWF) type A domain
NIOIMGPL_00165 4.2e-75
NIOIMGPL_00167 6.4e-290 S PGAP1-like protein
NIOIMGPL_00168 1.1e-280 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
NIOIMGPL_00169 0.0 S Lysylphosphatidylglycerol synthase TM region
NIOIMGPL_00170 8.1e-42 hup L Belongs to the bacterial histone-like protein family
NIOIMGPL_00171 1.9e-275 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NIOIMGPL_00172 1.6e-10 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NIOIMGPL_00173 2e-157 hisN 3.1.3.25 G Inositol monophosphatase family
NIOIMGPL_00174 2.4e-231 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
NIOIMGPL_00175 4.3e-62 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
NIOIMGPL_00176 0.0 arc O AAA ATPase forming ring-shaped complexes
NIOIMGPL_00177 6.6e-139 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
NIOIMGPL_00178 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIOIMGPL_00179 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIOIMGPL_00180 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIOIMGPL_00181 5.9e-74 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIOIMGPL_00182 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIOIMGPL_00183 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
NIOIMGPL_00184 6.7e-164 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NIOIMGPL_00185 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIOIMGPL_00186 0.0 ctpE P E1-E2 ATPase
NIOIMGPL_00187 4e-110
NIOIMGPL_00188 1.4e-247 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIOIMGPL_00189 7.5e-130 S Protein of unknown function (DUF3159)
NIOIMGPL_00190 3e-137 S Protein of unknown function (DUF3710)
NIOIMGPL_00191 3.7e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
NIOIMGPL_00192 8.7e-270 pepC 3.4.22.40 E Peptidase C1-like family
NIOIMGPL_00193 3.1e-309 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
NIOIMGPL_00194 0.0 oppD P Belongs to the ABC transporter superfamily
NIOIMGPL_00195 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
NIOIMGPL_00196 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00197 4.7e-185 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NIOIMGPL_00198 7.3e-42
NIOIMGPL_00199 3.2e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
NIOIMGPL_00200 6.5e-198 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
NIOIMGPL_00201 8.4e-80
NIOIMGPL_00202 0.0 typA T Elongation factor G C-terminus
NIOIMGPL_00203 4.4e-236 iscS1 2.8.1.7 E Aminotransferase class-V
NIOIMGPL_00204 2.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
NIOIMGPL_00205 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NIOIMGPL_00206 3.1e-250 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NIOIMGPL_00207 8.6e-150 nrtR 3.6.1.55 F NUDIX hydrolase
NIOIMGPL_00208 6e-112 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIOIMGPL_00209 1.2e-149 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIOIMGPL_00210 1.9e-46 soj D CobQ CobB MinD ParA nucleotide binding domain protein
NIOIMGPL_00211 4.9e-50 soj D CobQ CobB MinD ParA nucleotide binding domain protein
NIOIMGPL_00212 2.9e-179 xerD D recombinase XerD
NIOIMGPL_00213 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIOIMGPL_00214 2.1e-25 rpmI J Ribosomal protein L35
NIOIMGPL_00215 7e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIOIMGPL_00217 8e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
NIOIMGPL_00218 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIOIMGPL_00219 8.4e-93 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIOIMGPL_00221 2.2e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NIOIMGPL_00222 9.1e-194 galM 5.1.3.3 G Aldose 1-epimerase
NIOIMGPL_00223 2e-64
NIOIMGPL_00224 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
NIOIMGPL_00225 6.3e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIOIMGPL_00226 9.8e-191 V Acetyltransferase (GNAT) domain
NIOIMGPL_00227 2.2e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
NIOIMGPL_00228 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
NIOIMGPL_00229 1.6e-128 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
NIOIMGPL_00230 0.0 smc D Required for chromosome condensation and partitioning
NIOIMGPL_00231 1.4e-282 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
NIOIMGPL_00233 9.6e-97 3.6.1.55 F NUDIX domain
NIOIMGPL_00234 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
NIOIMGPL_00235 0.0 P Belongs to the ABC transporter superfamily
NIOIMGPL_00236 8.7e-191 dppC EP Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00237 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00238 9.4e-62 S AAA domain (dynein-related subfamily)
NIOIMGPL_00239 8.4e-69 S AAA domain (dynein-related subfamily)
NIOIMGPL_00240 5.2e-112 S Putative metallopeptidase domain
NIOIMGPL_00242 6.7e-09 K helix_turn _helix lactose operon repressor
NIOIMGPL_00243 6.1e-229 I Serine aminopeptidase, S33
NIOIMGPL_00244 2.2e-189 K Periplasmic binding protein domain
NIOIMGPL_00245 3.5e-187 G Glycosyl hydrolases family 43
NIOIMGPL_00247 9.1e-20 abfA1 3.2.1.55 GH51 G arabinose metabolic process
NIOIMGPL_00248 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
NIOIMGPL_00249 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIOIMGPL_00250 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIOIMGPL_00251 3.2e-93 S Protein of unknown function (DUF721)
NIOIMGPL_00252 4e-240 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIOIMGPL_00253 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIOIMGPL_00254 7e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIOIMGPL_00255 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NIOIMGPL_00256 6.7e-171 yidC U Membrane protein insertase, YidC Oxa1 family
NIOIMGPL_00257 6.5e-93 jag S Putative single-stranded nucleic acids-binding domain
NIOIMGPL_00258 2.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NIOIMGPL_00259 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
NIOIMGPL_00260 1.8e-243 parB K Belongs to the ParB family
NIOIMGPL_00261 3.8e-202 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIOIMGPL_00262 0.0 murJ KLT MviN-like protein
NIOIMGPL_00263 0.0 M Conserved repeat domain
NIOIMGPL_00264 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
NIOIMGPL_00265 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
NIOIMGPL_00266 6.7e-113 S LytR cell envelope-related transcriptional attenuator
NIOIMGPL_00267 1.2e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIOIMGPL_00268 6.3e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIOIMGPL_00269 6.6e-212 S G5
NIOIMGPL_00271 8.4e-151 O Thioredoxin
NIOIMGPL_00272 0.0 KLT Protein tyrosine kinase
NIOIMGPL_00273 3.4e-174 K Psort location Cytoplasmic, score
NIOIMGPL_00274 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
NIOIMGPL_00275 3.4e-100 L Helix-turn-helix domain
NIOIMGPL_00276 1.3e-38 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
NIOIMGPL_00277 7.6e-37 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
NIOIMGPL_00278 3e-184 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
NIOIMGPL_00279 3.2e-93
NIOIMGPL_00280 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIOIMGPL_00281 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIOIMGPL_00282 2.9e-96 T Forkhead associated domain
NIOIMGPL_00283 1.4e-67 B Belongs to the OprB family
NIOIMGPL_00284 1.3e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
NIOIMGPL_00285 1.3e-61 E Transglutaminase-like superfamily
NIOIMGPL_00286 1.5e-238 E Transglutaminase-like superfamily
NIOIMGPL_00287 1.8e-224 S Protein of unknown function DUF58
NIOIMGPL_00288 8.2e-230 S ATPase family associated with various cellular activities (AAA)
NIOIMGPL_00289 0.0 S Fibronectin type 3 domain
NIOIMGPL_00290 2.6e-269 KLT Protein tyrosine kinase
NIOIMGPL_00291 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
NIOIMGPL_00292 1.2e-188 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
NIOIMGPL_00293 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
NIOIMGPL_00294 3.4e-155 K -acetyltransferase
NIOIMGPL_00295 1.1e-248 G Major Facilitator Superfamily
NIOIMGPL_00296 2.3e-18 appF P Belongs to the ABC transporter superfamily
NIOIMGPL_00297 6.4e-24 relB L RelB antitoxin
NIOIMGPL_00298 2.8e-57 L Transposase
NIOIMGPL_00299 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIOIMGPL_00300 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIOIMGPL_00301 4.4e-113 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIOIMGPL_00302 3.6e-210 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIOIMGPL_00303 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
NIOIMGPL_00304 5.5e-285 O Subtilase family
NIOIMGPL_00305 1.4e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIOIMGPL_00306 2.6e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIOIMGPL_00307 1.4e-270 S zinc finger
NIOIMGPL_00308 1.5e-112 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NIOIMGPL_00309 2.9e-229 aspB E Aminotransferase class-V
NIOIMGPL_00310 5.6e-95 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
NIOIMGPL_00311 2.3e-37 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
NIOIMGPL_00312 1.8e-128 tmp1 S Domain of unknown function (DUF4391)
NIOIMGPL_00313 9.3e-115 moeB 2.7.7.80 H ThiF family
NIOIMGPL_00314 1.7e-254 cdr OP Sulfurtransferase TusA
NIOIMGPL_00315 2.8e-182 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NIOIMGPL_00317 1.9e-172 S Endonuclease/Exonuclease/phosphatase family
NIOIMGPL_00318 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIOIMGPL_00319 1.1e-272 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIOIMGPL_00320 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
NIOIMGPL_00321 4.3e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIOIMGPL_00323 3.1e-32 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
NIOIMGPL_00324 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
NIOIMGPL_00325 1.3e-108
NIOIMGPL_00326 5.9e-257 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
NIOIMGPL_00327 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
NIOIMGPL_00328 6.4e-55 plyA3 M Parallel beta-helix repeats
NIOIMGPL_00329 5.8e-89 K MarR family
NIOIMGPL_00330 0.0 V ABC transporter, ATP-binding protein
NIOIMGPL_00331 0.0 V ABC transporter transmembrane region
NIOIMGPL_00332 3.4e-167 S Patatin-like phospholipase
NIOIMGPL_00333 1.5e-152 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NIOIMGPL_00334 1.8e-167 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NIOIMGPL_00335 3.4e-115 S Vitamin K epoxide reductase
NIOIMGPL_00336 2.5e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
NIOIMGPL_00337 6.1e-32 S Protein of unknown function (DUF3107)
NIOIMGPL_00338 4.6e-245 mphA S Aminoglycoside phosphotransferase
NIOIMGPL_00339 1.5e-280 uvrD2 3.6.4.12 L DNA helicase
NIOIMGPL_00340 8.2e-285 S Zincin-like metallopeptidase
NIOIMGPL_00341 2.5e-59 lon T Belongs to the peptidase S16 family
NIOIMGPL_00342 7.1e-65 lon T Belongs to the peptidase S16 family
NIOIMGPL_00343 5.7e-47 S Protein of unknown function (DUF3052)
NIOIMGPL_00344 8.1e-196 K helix_turn _helix lactose operon repressor
NIOIMGPL_00345 1.2e-61 S Thiamine-binding protein
NIOIMGPL_00346 6.6e-43 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NIOIMGPL_00347 1.7e-25 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NIOIMGPL_00348 6.9e-231 O AAA domain (Cdc48 subfamily)
NIOIMGPL_00349 1.3e-84
NIOIMGPL_00350 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NIOIMGPL_00351 6.8e-159 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIOIMGPL_00352 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
NIOIMGPL_00353 1.4e-123 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
NIOIMGPL_00354 3.1e-289 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
NIOIMGPL_00355 4.7e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIOIMGPL_00356 2.8e-230 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIOIMGPL_00357 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIOIMGPL_00358 3.7e-42 yggT S YGGT family
NIOIMGPL_00359 9.7e-90 3.1.21.3 V DivIVA protein
NIOIMGPL_00360 1.4e-100 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIOIMGPL_00361 3.4e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NIOIMGPL_00363 6e-63
NIOIMGPL_00364 2.3e-23 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NIOIMGPL_00365 5.9e-12 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NIOIMGPL_00366 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIOIMGPL_00367 8.7e-201 ftsE D Cell division ATP-binding protein FtsE
NIOIMGPL_00368 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
NIOIMGPL_00369 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
NIOIMGPL_00370 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIOIMGPL_00371 1.9e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
NIOIMGPL_00372 1e-81
NIOIMGPL_00374 1e-189 2.7.11.1 NU Tfp pilus assembly protein FimV
NIOIMGPL_00375 1.5e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NIOIMGPL_00376 1e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NIOIMGPL_00377 1.4e-262 I acetylesterase activity
NIOIMGPL_00378 2.7e-143 recO L Involved in DNA repair and RecF pathway recombination
NIOIMGPL_00379 1.8e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIOIMGPL_00380 4.3e-191 ywqG S Domain of unknown function (DUF1963)
NIOIMGPL_00381 3.1e-19 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
NIOIMGPL_00382 3e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
NIOIMGPL_00383 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
NIOIMGPL_00384 3.1e-96 S zinc-ribbon domain
NIOIMGPL_00385 2e-46 yhbY J CRS1_YhbY
NIOIMGPL_00386 0.0 4.2.1.53 S MCRA family
NIOIMGPL_00389 3.4e-202 K WYL domain
NIOIMGPL_00390 1.3e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
NIOIMGPL_00391 1.6e-168 dkgA 1.1.1.346 C Aldo/keto reductase family
NIOIMGPL_00392 3.4e-76 yneG S Domain of unknown function (DUF4186)
NIOIMGPL_00394 8.9e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NIOIMGPL_00395 3.2e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIOIMGPL_00396 3.7e-218 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NIOIMGPL_00397 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
NIOIMGPL_00398 1.7e-112
NIOIMGPL_00399 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIOIMGPL_00400 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
NIOIMGPL_00401 1.4e-283 S Uncharacterized protein conserved in bacteria (DUF2252)
NIOIMGPL_00402 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
NIOIMGPL_00403 6e-139 S Domain of unknown function (DUF5067)
NIOIMGPL_00404 5.5e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NIOIMGPL_00405 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
NIOIMGPL_00406 2.7e-120 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
NIOIMGPL_00407 1.2e-171
NIOIMGPL_00408 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIOIMGPL_00409 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
NIOIMGPL_00410 2.3e-165 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIOIMGPL_00411 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIOIMGPL_00412 6.1e-45 M Lysin motif
NIOIMGPL_00413 8.8e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIOIMGPL_00414 1.7e-210 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NIOIMGPL_00415 0.0 L DNA helicase
NIOIMGPL_00416 1.3e-90 mraZ K Belongs to the MraZ family
NIOIMGPL_00417 7.8e-189 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIOIMGPL_00418 4.1e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NIOIMGPL_00419 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
NIOIMGPL_00420 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIOIMGPL_00421 3.2e-281 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIOIMGPL_00422 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIOIMGPL_00423 5.5e-245 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIOIMGPL_00424 9e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
NIOIMGPL_00425 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIOIMGPL_00426 2.9e-293 murC 6.3.2.8 M Belongs to the MurCDEF family
NIOIMGPL_00427 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
NIOIMGPL_00428 4.9e-37
NIOIMGPL_00430 2.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIOIMGPL_00431 1.3e-235 G Major Facilitator Superfamily
NIOIMGPL_00432 5.6e-169 2.7.1.4 G pfkB family carbohydrate kinase
NIOIMGPL_00433 1.3e-224 GK ROK family
NIOIMGPL_00434 2.2e-131 cutC P Participates in the control of copper homeostasis
NIOIMGPL_00435 4.1e-173 GK ROK family
NIOIMGPL_00436 4e-150 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIOIMGPL_00437 6.2e-243 nagA 3.5.1.25 G Amidohydrolase family
NIOIMGPL_00438 0.0 yegQ O Peptidase family U32 C-terminal domain
NIOIMGPL_00439 8.7e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
NIOIMGPL_00440 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NIOIMGPL_00441 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NIOIMGPL_00442 3.3e-41 D nuclear chromosome segregation
NIOIMGPL_00443 7.1e-269 pepC 3.4.22.40 E Peptidase C1-like family
NIOIMGPL_00444 7.8e-167 L Excalibur calcium-binding domain
NIOIMGPL_00445 1.5e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIOIMGPL_00446 1.8e-243 EGP Major facilitator Superfamily
NIOIMGPL_00447 9.7e-109 K helix_turn_helix, Arsenical Resistance Operon Repressor
NIOIMGPL_00448 8.3e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIOIMGPL_00449 4.3e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIOIMGPL_00450 1.7e-241 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NIOIMGPL_00451 1.3e-128 KT Transcriptional regulatory protein, C terminal
NIOIMGPL_00452 2.3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
NIOIMGPL_00453 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
NIOIMGPL_00454 6.2e-180 pstA P Phosphate transport system permease
NIOIMGPL_00455 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIOIMGPL_00456 1.7e-168 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NIOIMGPL_00457 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
NIOIMGPL_00458 8.8e-222 pbuO S Permease family
NIOIMGPL_00460 1e-207 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
NIOIMGPL_00461 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
NIOIMGPL_00462 2.2e-130 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
NIOIMGPL_00463 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIOIMGPL_00464 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIOIMGPL_00466 5.2e-245 T Forkhead associated domain
NIOIMGPL_00467 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
NIOIMGPL_00468 9.6e-42
NIOIMGPL_00469 3.6e-109 flgA NO SAF
NIOIMGPL_00470 3.2e-38 fmdB S Putative regulatory protein
NIOIMGPL_00471 1.8e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
NIOIMGPL_00472 3.2e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
NIOIMGPL_00473 1.5e-111 V Type II restriction enzyme, methylase
NIOIMGPL_00474 5.1e-44 V Type II restriction enzyme, methylase
NIOIMGPL_00475 4.2e-95 V Type II restriction enzyme, methylase
NIOIMGPL_00476 6.1e-25 hepA L SNF2 family N-terminal domain
NIOIMGPL_00477 1.1e-95 hepA L SNF2 family N-terminal domain
NIOIMGPL_00478 1.7e-68
NIOIMGPL_00479 9.7e-115 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIOIMGPL_00480 1.2e-165 S Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_00481 2.1e-94 P ABC-type metal ion transport system permease component
NIOIMGPL_00482 1.7e-223 S Peptidase dimerisation domain
NIOIMGPL_00483 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIOIMGPL_00484 6.4e-40
NIOIMGPL_00485 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NIOIMGPL_00486 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIOIMGPL_00487 4.4e-114 S Protein of unknown function (DUF3000)
NIOIMGPL_00488 7e-250 rnd 3.1.13.5 J 3'-5' exonuclease
NIOIMGPL_00489 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIOIMGPL_00490 1.9e-54 clcA_2 P Voltage gated chloride channel
NIOIMGPL_00491 6.9e-176 clcA_2 P Voltage gated chloride channel
NIOIMGPL_00493 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIOIMGPL_00494 1.5e-23 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIOIMGPL_00495 3.3e-77 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIOIMGPL_00496 1e-243 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIOIMGPL_00499 1.9e-233 patB 4.4.1.8 E Aminotransferase, class I II
NIOIMGPL_00500 1.6e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NIOIMGPL_00501 1.8e-165 fmt2 3.2.2.10 S Belongs to the LOG family
NIOIMGPL_00502 5.7e-118 safC S O-methyltransferase
NIOIMGPL_00503 6.6e-184 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
NIOIMGPL_00504 3e-71 yraN L Belongs to the UPF0102 family
NIOIMGPL_00505 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
NIOIMGPL_00506 6.7e-284 dprA 5.99.1.2 LU DNA recombination-mediator protein A
NIOIMGPL_00507 1.3e-57 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NIOIMGPL_00508 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
NIOIMGPL_00509 1.3e-90 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NIOIMGPL_00510 3.9e-142 S Putative ABC-transporter type IV
NIOIMGPL_00511 5e-251 metY 2.5.1.49 E Aminotransferase class-V
NIOIMGPL_00512 8.9e-163 V ABC transporter, ATP-binding protein
NIOIMGPL_00513 4e-216 MV MacB-like periplasmic core domain
NIOIMGPL_00514 6.4e-217 MV MacB-like periplasmic core domain
NIOIMGPL_00515 0.0 phoN I PAP2 superfamily
NIOIMGPL_00516 2.5e-49 K helix_turn_helix, Lux Regulon
NIOIMGPL_00517 5.5e-31 K helix_turn_helix, Lux Regulon
NIOIMGPL_00518 0.0 tcsS2 T Histidine kinase
NIOIMGPL_00519 3.6e-263 pip 3.4.11.5 S alpha/beta hydrolase fold
NIOIMGPL_00520 7.2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIOIMGPL_00521 1.9e-167 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
NIOIMGPL_00522 1.6e-146 P NLPA lipoprotein
NIOIMGPL_00523 1.9e-186 acoA 1.2.4.1 C Dehydrogenase E1 component
NIOIMGPL_00524 3.9e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
NIOIMGPL_00525 3e-204 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIOIMGPL_00526 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00527 4.9e-229 mtnE 2.6.1.83 E Aminotransferase class I and II
NIOIMGPL_00528 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIOIMGPL_00529 9.5e-22 XK27_00240 K Fic/DOC family
NIOIMGPL_00530 1.4e-207 XK27_00240 K Fic/DOC family
NIOIMGPL_00531 2.5e-119 E Psort location Cytoplasmic, score 8.87
NIOIMGPL_00532 5.6e-59 yccF S Inner membrane component domain
NIOIMGPL_00533 1.5e-155 ksgA 2.1.1.182 J Methyltransferase domain
NIOIMGPL_00534 3.9e-59 S Cupin 2, conserved barrel domain protein
NIOIMGPL_00535 4.1e-250 KLT Protein tyrosine kinase
NIOIMGPL_00536 4.5e-79 K Psort location Cytoplasmic, score
NIOIMGPL_00537 1.2e-148
NIOIMGPL_00538 4e-09
NIOIMGPL_00539 2.7e-22
NIOIMGPL_00540 1.3e-197 S Short C-terminal domain
NIOIMGPL_00541 1.2e-89 S Helix-turn-helix
NIOIMGPL_00542 2.8e-66 S Zincin-like metallopeptidase
NIOIMGPL_00543 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NIOIMGPL_00544 1.5e-24
NIOIMGPL_00545 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NIOIMGPL_00546 1e-124 ypfH S Phospholipase/Carboxylesterase
NIOIMGPL_00547 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
NIOIMGPL_00549 1.7e-290 2.4.1.166 GT2 M Glycosyltransferase like family 2
NIOIMGPL_00550 4.2e-118 3.1.3.27 E haloacid dehalogenase-like hydrolase
NIOIMGPL_00551 1.9e-144 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
NIOIMGPL_00552 2.7e-186 MA20_14895 S Conserved hypothetical protein 698
NIOIMGPL_00553 8.7e-56 estB S Phospholipase/Carboxylesterase
NIOIMGPL_00554 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
NIOIMGPL_00555 2.4e-237 rutG F Permease family
NIOIMGPL_00556 2e-57 K AraC-like ligand binding domain
NIOIMGPL_00558 3.7e-51 IQ oxidoreductase activity
NIOIMGPL_00559 4.2e-136 ybbM V Uncharacterised protein family (UPF0014)
NIOIMGPL_00560 7.5e-135 ybbL V ATPases associated with a variety of cellular activities
NIOIMGPL_00561 3.2e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIOIMGPL_00562 2.5e-91 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIOIMGPL_00563 2.7e-125 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
NIOIMGPL_00564 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
NIOIMGPL_00565 1.4e-89
NIOIMGPL_00566 1e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NIOIMGPL_00567 1.3e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIOIMGPL_00568 9.2e-164 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NIOIMGPL_00569 9.5e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
NIOIMGPL_00570 9.5e-183 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIOIMGPL_00571 1.4e-84 argR K Regulates arginine biosynthesis genes
NIOIMGPL_00572 5e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIOIMGPL_00573 1.6e-53 3.1.21.3 V type I restriction modification DNA specificity domain
NIOIMGPL_00574 8.2e-176 L Phage integrase family
NIOIMGPL_00575 2.4e-139 S LPXTG-motif cell wall anchor domain protein
NIOIMGPL_00576 4.1e-284 S LPXTG-motif cell wall anchor domain protein
NIOIMGPL_00577 1.7e-114 S LPXTG-motif cell wall anchor domain protein
NIOIMGPL_00578 1e-187 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIOIMGPL_00579 2.8e-154 sapF E ATPases associated with a variety of cellular activities
NIOIMGPL_00580 3.3e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
NIOIMGPL_00581 1.4e-162 EP Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00582 5.5e-170 P Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00583 4.6e-310 E ABC transporter, substrate-binding protein, family 5
NIOIMGPL_00584 1.1e-142 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NIOIMGPL_00585 1.7e-273 G Bacterial extracellular solute-binding protein
NIOIMGPL_00586 5.7e-58 G carbohydrate transport
NIOIMGPL_00587 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NIOIMGPL_00588 1.6e-64 G ABC transporter permease
NIOIMGPL_00589 7.7e-43 G ABC transporter permease
NIOIMGPL_00590 9.4e-186 K Periplasmic binding protein domain
NIOIMGPL_00591 2.9e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NIOIMGPL_00592 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
NIOIMGPL_00594 5.4e-125 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIOIMGPL_00595 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIOIMGPL_00596 8.5e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NIOIMGPL_00597 4.9e-276 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
NIOIMGPL_00598 2.3e-60 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
NIOIMGPL_00599 1.9e-251 V Type I restriction-modification system methyltransferase subunit()
NIOIMGPL_00600 1.1e-23 relB L RelB antitoxin
NIOIMGPL_00601 7.3e-81 L Transposase
NIOIMGPL_00602 9.2e-127 XK27_08050 O prohibitin homologues
NIOIMGPL_00603 4.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
NIOIMGPL_00604 2e-233 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NIOIMGPL_00605 1.4e-259 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
NIOIMGPL_00606 2.9e-224 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NIOIMGPL_00607 0.0 macB_2 V ATPases associated with a variety of cellular activities
NIOIMGPL_00608 1.8e-32 ctpE P E1-E2 ATPase
NIOIMGPL_00609 2.4e-184 ctpE P E1-E2 ATPase
NIOIMGPL_00610 2.9e-54 racA K MerR, DNA binding
NIOIMGPL_00611 8.4e-198 yghZ C Aldo/keto reductase family
NIOIMGPL_00612 1.9e-100 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
NIOIMGPL_00613 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
NIOIMGPL_00614 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
NIOIMGPL_00615 3.8e-125 S Short repeat of unknown function (DUF308)
NIOIMGPL_00616 0.0 pepO 3.4.24.71 O Peptidase family M13
NIOIMGPL_00617 1.6e-40 pepO 3.4.24.71 O Peptidase family M13
NIOIMGPL_00618 8.2e-117 L Single-strand binding protein family
NIOIMGPL_00619 2.6e-43
NIOIMGPL_00620 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIOIMGPL_00622 1e-270 recD2 3.6.4.12 L PIF1-like helicase
NIOIMGPL_00623 7.6e-160 supH S Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_00624 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NIOIMGPL_00625 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
NIOIMGPL_00626 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NIOIMGPL_00627 1e-191 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
NIOIMGPL_00628 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
NIOIMGPL_00629 4.1e-20 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
NIOIMGPL_00630 6.3e-179 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIOIMGPL_00631 1.3e-188 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIOIMGPL_00632 3.9e-36 rpmE J Binds the 23S rRNA
NIOIMGPL_00634 2.9e-193 K helix_turn_helix, arabinose operon control protein
NIOIMGPL_00635 2.6e-163 glcU G Sugar transport protein
NIOIMGPL_00636 5.7e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
NIOIMGPL_00637 6e-257 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
NIOIMGPL_00638 1.4e-106
NIOIMGPL_00639 1.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
NIOIMGPL_00640 1.4e-140 3.5.2.6 V Beta-lactamase enzyme family
NIOIMGPL_00641 4.1e-244 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
NIOIMGPL_00642 1.1e-45
NIOIMGPL_00643 4.7e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
NIOIMGPL_00644 7.1e-64 S Protein of unknown function (DUF4235)
NIOIMGPL_00645 1.2e-131 G Phosphoglycerate mutase family
NIOIMGPL_00648 2.9e-190 K Psort location Cytoplasmic, score
NIOIMGPL_00649 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
NIOIMGPL_00650 0.0 dnaK O Heat shock 70 kDa protein
NIOIMGPL_00651 1.4e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIOIMGPL_00652 1.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
NIOIMGPL_00653 1.2e-86 hspR K transcriptional regulator, MerR family
NIOIMGPL_00654 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
NIOIMGPL_00655 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
NIOIMGPL_00656 1.8e-133 S HAD hydrolase, family IA, variant 3
NIOIMGPL_00658 2.7e-126 dedA S SNARE associated Golgi protein
NIOIMGPL_00659 2.3e-168 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIOIMGPL_00660 1.5e-58
NIOIMGPL_00661 3.6e-130
NIOIMGPL_00662 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIOIMGPL_00663 1.2e-80 K Transcriptional regulator
NIOIMGPL_00664 5.3e-42 xylR 5.3.1.12 G MFS/sugar transport protein
NIOIMGPL_00665 9.9e-62 xylR 5.3.1.12 G MFS/sugar transport protein
NIOIMGPL_00666 1.1e-130 xylR 5.3.1.12 G MFS/sugar transport protein
NIOIMGPL_00667 5.9e-185 tatD L TatD related DNase
NIOIMGPL_00668 0.0 kup P Transport of potassium into the cell
NIOIMGPL_00670 1.3e-162 S Glutamine amidotransferase domain
NIOIMGPL_00671 4.6e-137 T HD domain
NIOIMGPL_00672 4.2e-181 V ABC transporter
NIOIMGPL_00673 1.4e-246 V ABC transporter permease
NIOIMGPL_00674 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
NIOIMGPL_00675 0.0 S Psort location Cytoplasmic, score 8.87
NIOIMGPL_00676 9.2e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NIOIMGPL_00677 8.7e-27 thiS 2.8.1.10 H ThiS family
NIOIMGPL_00678 5e-276
NIOIMGPL_00679 2.4e-64 S Glycosyltransferase, group 2 family protein
NIOIMGPL_00680 1.5e-79 L Phage integrase family
NIOIMGPL_00681 5.7e-94 L Phage integrase family
NIOIMGPL_00682 3.1e-206 E Belongs to the peptidase S1B family
NIOIMGPL_00683 1.1e-12
NIOIMGPL_00684 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIOIMGPL_00685 1.7e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NIOIMGPL_00686 1.4e-47 S Domain of unknown function (DUF4193)
NIOIMGPL_00687 8.9e-174 S Protein of unknown function (DUF3071)
NIOIMGPL_00688 1.9e-236 S Type I phosphodiesterase / nucleotide pyrophosphatase
NIOIMGPL_00689 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
NIOIMGPL_00690 0.0 lhr L DEAD DEAH box helicase
NIOIMGPL_00691 6e-124 lhr L DEAD DEAH box helicase
NIOIMGPL_00692 1.1e-15 K Transcriptional regulator
NIOIMGPL_00693 4.9e-276 aspA 4.3.1.1 E Fumarase C C-terminus
NIOIMGPL_00694 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
NIOIMGPL_00695 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIOIMGPL_00696 1.7e-122
NIOIMGPL_00697 1.5e-200 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
NIOIMGPL_00698 0.0 pknL 2.7.11.1 KLT PASTA
NIOIMGPL_00699 5.1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
NIOIMGPL_00700 1.5e-109
NIOIMGPL_00701 1.1e-192 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIOIMGPL_00702 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIOIMGPL_00703 2.8e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIOIMGPL_00705 1.1e-86 recX S Modulates RecA activity
NIOIMGPL_00706 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIOIMGPL_00707 3.7e-40 S Protein of unknown function (DUF3046)
NIOIMGPL_00708 1.4e-79 K Helix-turn-helix XRE-family like proteins
NIOIMGPL_00709 1.4e-37 cinA 3.5.1.42 S Belongs to the CinA family
NIOIMGPL_00710 4.5e-123 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIOIMGPL_00711 6.8e-144 cobB2 K Sir2 family
NIOIMGPL_00712 2.2e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
NIOIMGPL_00713 3.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIOIMGPL_00714 4.4e-143 ypfH S Phospholipase/Carboxylesterase
NIOIMGPL_00715 0.0 yjcE P Sodium/hydrogen exchanger family
NIOIMGPL_00716 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
NIOIMGPL_00717 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
NIOIMGPL_00718 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
NIOIMGPL_00720 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIOIMGPL_00721 7.5e-269 KLT Domain of unknown function (DUF4032)
NIOIMGPL_00722 8.8e-43
NIOIMGPL_00723 6.4e-87 3.4.22.70 M Sortase family
NIOIMGPL_00724 5e-57 3.4.22.70 M Sortase family
NIOIMGPL_00725 1.5e-74 I ASCH
NIOIMGPL_00727 1.2e-68
NIOIMGPL_00729 2.4e-43 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
NIOIMGPL_00730 1.1e-15 K Transcriptional regulator
NIOIMGPL_00731 7.5e-91 MA20_25245 K FR47-like protein
NIOIMGPL_00732 4.4e-120 ydaF_1 J Acetyltransferase (GNAT) domain
NIOIMGPL_00733 1.5e-64 yeaO K Protein of unknown function, DUF488
NIOIMGPL_00734 2.5e-163 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NIOIMGPL_00735 1.4e-284 S Psort location Cytoplasmic, score 8.87
NIOIMGPL_00736 1.2e-61 S Domain of unknown function (DUF4194)
NIOIMGPL_00737 0.0 S Psort location Cytoplasmic, score 8.87
NIOIMGPL_00738 3.9e-290 E Serine carboxypeptidase
NIOIMGPL_00739 4.6e-144 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NIOIMGPL_00740 3.7e-171 corA P CorA-like Mg2+ transporter protein
NIOIMGPL_00741 9.5e-164 ET Bacterial periplasmic substrate-binding proteins
NIOIMGPL_00742 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIOIMGPL_00743 2.4e-94 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
NIOIMGPL_00744 0.0 comE S Competence protein
NIOIMGPL_00745 1.1e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
NIOIMGPL_00746 1.2e-111 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
NIOIMGPL_00747 5.4e-161 yeaZ 2.3.1.234 O Glycoprotease family
NIOIMGPL_00748 2.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
NIOIMGPL_00749 1.4e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIOIMGPL_00751 3.1e-131 M Peptidase family M23
NIOIMGPL_00752 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
NIOIMGPL_00753 2.3e-274 G ABC transporter substrate-binding protein
NIOIMGPL_00754 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
NIOIMGPL_00755 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
NIOIMGPL_00756 5.7e-91
NIOIMGPL_00757 4.7e-26 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
NIOIMGPL_00758 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
NIOIMGPL_00759 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIOIMGPL_00760 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
NIOIMGPL_00761 2.4e-30
NIOIMGPL_00762 5.5e-118 S Domain of unknown function (DUF4357)
NIOIMGPL_00763 7.1e-186 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
NIOIMGPL_00764 4.4e-92 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
NIOIMGPL_00765 1.3e-171 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
NIOIMGPL_00766 8.2e-74 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
NIOIMGPL_00767 1e-94 3.6.4.12 K Putative DNA-binding domain
NIOIMGPL_00768 1.6e-139 3.6.4.12 K Putative DNA-binding domain
NIOIMGPL_00769 8.7e-236 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NIOIMGPL_00770 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NIOIMGPL_00771 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
NIOIMGPL_00772 1e-107 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIOIMGPL_00773 4.6e-143 S Putative ABC-transporter type IV
NIOIMGPL_00774 5.4e-253 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIOIMGPL_00777 2.5e-153 L Tetratricopeptide repeat
NIOIMGPL_00778 8.6e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NIOIMGPL_00780 2.4e-136 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NIOIMGPL_00781 3.1e-103
NIOIMGPL_00782 6.8e-116 trkA P TrkA-N domain
NIOIMGPL_00783 3.5e-237 trkB P Cation transport protein
NIOIMGPL_00784 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIOIMGPL_00785 3.5e-292 recN L May be involved in recombinational repair of damaged DNA
NIOIMGPL_00786 5.8e-123 S Haloacid dehalogenase-like hydrolase
NIOIMGPL_00787 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
NIOIMGPL_00788 3.8e-176 V ATPases associated with a variety of cellular activities
NIOIMGPL_00789 1e-123 S ABC-2 family transporter protein
NIOIMGPL_00790 4e-122 S ABC-2 family transporter protein
NIOIMGPL_00791 6.6e-284 thrC 4.2.3.1 E Threonine synthase N terminus
NIOIMGPL_00792 4.3e-91 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIOIMGPL_00793 7.7e-143 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIOIMGPL_00794 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
NIOIMGPL_00795 1e-131 yebC K transcriptional regulatory protein
NIOIMGPL_00796 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NIOIMGPL_00798 3.3e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIOIMGPL_00799 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIOIMGPL_00800 2.6e-44 yajC U Preprotein translocase subunit
NIOIMGPL_00801 7.2e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIOIMGPL_00802 9.6e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NIOIMGPL_00803 1.9e-120 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NIOIMGPL_00804 5.8e-83
NIOIMGPL_00805 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NIOIMGPL_00806 5.7e-30
NIOIMGPL_00807 4.1e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NIOIMGPL_00808 6.3e-145 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NIOIMGPL_00809 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
NIOIMGPL_00810 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NIOIMGPL_00811 1.3e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NIOIMGPL_00812 1.3e-179 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIOIMGPL_00813 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
NIOIMGPL_00814 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
NIOIMGPL_00815 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
NIOIMGPL_00816 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIOIMGPL_00817 9e-173 S Bacterial protein of unknown function (DUF881)
NIOIMGPL_00818 2.6e-31 sbp S Protein of unknown function (DUF1290)
NIOIMGPL_00819 2.5e-84 S Bacterial protein of unknown function (DUF881)
NIOIMGPL_00820 6.7e-41 S Bacterial protein of unknown function (DUF881)
NIOIMGPL_00821 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
NIOIMGPL_00822 1.2e-118 K helix_turn_helix, mercury resistance
NIOIMGPL_00823 1.9e-62
NIOIMGPL_00825 7.3e-143 pgp 3.1.3.18 S HAD-hyrolase-like
NIOIMGPL_00826 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NIOIMGPL_00827 0.0 helY L DEAD DEAH box helicase
NIOIMGPL_00828 4.9e-20
NIOIMGPL_00829 4.8e-267 pafB K WYL domain
NIOIMGPL_00830 2.4e-24 pafB K WYL domain
NIOIMGPL_00831 6.9e-116 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
NIOIMGPL_00833 5.5e-275 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
NIOIMGPL_00834 1.2e-248 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIOIMGPL_00837 5.8e-09
NIOIMGPL_00838 1.8e-69
NIOIMGPL_00839 1.2e-111
NIOIMGPL_00843 2.8e-156 S PAC2 family
NIOIMGPL_00844 6.6e-29 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIOIMGPL_00845 1.1e-124 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIOIMGPL_00846 6e-159 G Fructosamine kinase
NIOIMGPL_00847 1.9e-209 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIOIMGPL_00848 8.7e-94 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIOIMGPL_00849 2.5e-52 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIOIMGPL_00850 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
NIOIMGPL_00851 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIOIMGPL_00852 3.1e-142 yoaK S Protein of unknown function (DUF1275)
NIOIMGPL_00853 3.4e-253 brnQ U Component of the transport system for branched-chain amino acids
NIOIMGPL_00855 2e-242 mepA_6 V MatE
NIOIMGPL_00856 8e-162 S Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_00857 9.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NIOIMGPL_00858 8e-33 secG U Preprotein translocase SecG subunit
NIOIMGPL_00859 3.7e-134 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIOIMGPL_00860 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
NIOIMGPL_00861 5.6e-124 whiA K May be required for sporulation
NIOIMGPL_00862 1.5e-177 rapZ S Displays ATPase and GTPase activities
NIOIMGPL_00863 3e-181 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
NIOIMGPL_00864 1.2e-70 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIOIMGPL_00865 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIOIMGPL_00866 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIOIMGPL_00867 1.2e-77
NIOIMGPL_00869 3.3e-118 K Transcriptional regulatory protein, C terminal
NIOIMGPL_00870 2.5e-240 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NIOIMGPL_00871 1.7e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NIOIMGPL_00872 3.7e-301 ybiT S ABC transporter
NIOIMGPL_00873 7.2e-197 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NIOIMGPL_00874 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NIOIMGPL_00875 1.4e-206 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
NIOIMGPL_00876 1.4e-217 GK ROK family
NIOIMGPL_00877 4.3e-52 2.7.1.2 GK ROK family
NIOIMGPL_00878 6.1e-72 2.7.1.2 GK ROK family
NIOIMGPL_00879 1.4e-158 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_00880 8.3e-148 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_00881 5e-168 G ABC transporter permease
NIOIMGPL_00882 1.1e-173 G Binding-protein-dependent transport system inner membrane component
NIOIMGPL_00883 2.2e-243 G Bacterial extracellular solute-binding protein
NIOIMGPL_00884 1.3e-309 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIOIMGPL_00885 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIOIMGPL_00886 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIOIMGPL_00887 9.8e-230 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NIOIMGPL_00888 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
NIOIMGPL_00889 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIOIMGPL_00890 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NIOIMGPL_00891 3.7e-37 3.2.1.8 S alpha beta
NIOIMGPL_00892 1.9e-69 3.2.1.8 S alpha beta
NIOIMGPL_00893 8.4e-31 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIOIMGPL_00894 2.8e-16 kdgR K transcriptional regulator
NIOIMGPL_00895 3.6e-33 ebgC G YhcH YjgK YiaL family
NIOIMGPL_00896 7.1e-07
NIOIMGPL_00897 3e-46 G Exopolysaccharide biosynthesis protein
NIOIMGPL_00898 3.8e-145 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIOIMGPL_00899 2.6e-92
NIOIMGPL_00900 8.1e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIOIMGPL_00901 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIOIMGPL_00902 1.2e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIOIMGPL_00903 9.3e-69 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIOIMGPL_00904 1.9e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NIOIMGPL_00905 1.3e-78 S Bacterial PH domain
NIOIMGPL_00906 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
NIOIMGPL_00908 1.2e-108
NIOIMGPL_00909 2.5e-132 C Putative TM nitroreductase
NIOIMGPL_00910 1e-141 yijF S Domain of unknown function (DUF1287)
NIOIMGPL_00911 2.7e-70 pdxH S Pfam:Pyridox_oxidase
NIOIMGPL_00912 4.6e-146 KT RESPONSE REGULATOR receiver
NIOIMGPL_00913 4.1e-192 V VanZ like family
NIOIMGPL_00914 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
NIOIMGPL_00915 1.2e-97 ypjC S Putative ABC-transporter type IV
NIOIMGPL_00916 5.7e-158
NIOIMGPL_00918 1.6e-96 EGP Major facilitator Superfamily
NIOIMGPL_00919 1.8e-151 rpoC M heme binding
NIOIMGPL_00920 2.5e-80 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIOIMGPL_00921 1.3e-125
NIOIMGPL_00922 4.7e-131 S SOS response associated peptidase (SRAP)
NIOIMGPL_00923 1.9e-75 qseC 2.7.13.3 T Histidine kinase
NIOIMGPL_00924 1.4e-81 S Acetyltransferase (GNAT) domain
NIOIMGPL_00925 6.8e-98
NIOIMGPL_00926 0.0 XK27_00515 D Cell surface antigen C-terminus
NIOIMGPL_00927 5.2e-26
NIOIMGPL_00928 5.1e-95
NIOIMGPL_00929 1.6e-63 S PrgI family protein
NIOIMGPL_00930 0.0 trsE U type IV secretory pathway VirB4
NIOIMGPL_00931 2.9e-206 isp2 3.2.1.96 M CHAP domain
NIOIMGPL_00932 3.6e-14 U Type IV secretory system Conjugative DNA transfer
NIOIMGPL_00933 3.3e-110
NIOIMGPL_00935 1.1e-100 K Helix-turn-helix domain protein
NIOIMGPL_00937 1.8e-270 U Type IV secretory system Conjugative DNA transfer
NIOIMGPL_00938 4.2e-33 dapE 3.5.1.18 E Peptidase dimerisation domain
NIOIMGPL_00939 0.0 rne 3.1.26.12 J Ribonuclease E/G family
NIOIMGPL_00940 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
NIOIMGPL_00941 3.1e-40 rpmA J Ribosomal L27 protein
NIOIMGPL_00942 2.2e-215 K Psort location Cytoplasmic, score
NIOIMGPL_00943 4.8e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIOIMGPL_00944 1.5e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIOIMGPL_00945 4e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
NIOIMGPL_00947 2.1e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIOIMGPL_00948 3.6e-109 nusG K Participates in transcription elongation, termination and antitermination
NIOIMGPL_00949 1.5e-163 plsC2 2.3.1.51 I Phosphate acyltransferases
NIOIMGPL_00950 9.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NIOIMGPL_00951 1.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NIOIMGPL_00952 3.7e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NIOIMGPL_00953 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
NIOIMGPL_00954 3.4e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIOIMGPL_00955 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIOIMGPL_00956 3.1e-117
NIOIMGPL_00957 1.5e-163 T Pfam Adenylate and Guanylate cyclase catalytic domain
NIOIMGPL_00958 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NIOIMGPL_00959 1.1e-79 ssb1 L Single-stranded DNA-binding protein
NIOIMGPL_00960 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIOIMGPL_00961 6.6e-70 rplI J Binds to the 23S rRNA
NIOIMGPL_00962 5.2e-23 S Parallel beta-helix repeats
NIOIMGPL_00963 1e-66 E Domain of unknown function (DUF5011)
NIOIMGPL_00965 1.1e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NIOIMGPL_00966 3.9e-129 M Protein of unknown function (DUF3152)
NIOIMGPL_00967 3.1e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIOIMGPL_00968 2.7e-146 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NIOIMGPL_00969 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
NIOIMGPL_00970 0.0 inlJ M domain protein
NIOIMGPL_00971 1.1e-276 M LPXTG cell wall anchor motif
NIOIMGPL_00972 6.3e-213 3.4.22.70 M Sortase family
NIOIMGPL_00973 3.3e-72 S Domain of unknown function (DUF4854)
NIOIMGPL_00974 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
NIOIMGPL_00975 1.9e-30 2.1.1.72 S Protein conserved in bacteria
NIOIMGPL_00976 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIOIMGPL_00977 1.8e-131 M Mechanosensitive ion channel
NIOIMGPL_00978 3.8e-119 K Bacterial regulatory proteins, tetR family
NIOIMGPL_00979 2e-208 MA20_36090 S Psort location Cytoplasmic, score 8.87
NIOIMGPL_00980 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
NIOIMGPL_00981 8.5e-66
NIOIMGPL_00983 7.2e-43 K Transcriptional regulator
NIOIMGPL_00984 0.0 fadD 6.2.1.3 I AMP-binding enzyme
NIOIMGPL_00986 1.6e-32
NIOIMGPL_00991 2.6e-132 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
NIOIMGPL_00992 8.8e-226 K Helix-turn-helix XRE-family like proteins
NIOIMGPL_00993 3.2e-33 3.4.11.5 I carboxylic ester hydrolase activity
NIOIMGPL_00994 3.9e-190 L Transposase
NIOIMGPL_00995 8.6e-21 relB L RelB antitoxin
NIOIMGPL_00996 5.6e-119 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NIOIMGPL_00997 3e-74
NIOIMGPL_00998 1.8e-53 relB L RelB antitoxin
NIOIMGPL_00999 5e-60 T Toxic component of a toxin-antitoxin (TA) module
NIOIMGPL_01000 2e-132 K helix_turn_helix, mercury resistance
NIOIMGPL_01001 4.3e-242 yxiO S Vacuole effluxer Atg22 like
NIOIMGPL_01003 6.5e-201 yegV G pfkB family carbohydrate kinase
NIOIMGPL_01004 1.4e-29 rpmB J Ribosomal L28 family
NIOIMGPL_01005 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
NIOIMGPL_01006 7.2e-218 steT E amino acid
NIOIMGPL_01008 0.0
NIOIMGPL_01009 5.1e-245 U Sodium:dicarboxylate symporter family
NIOIMGPL_01010 6.8e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
NIOIMGPL_01012 4.1e-107 XK27_02070 S Nitroreductase family
NIOIMGPL_01013 8.3e-81 hsp20 O Hsp20/alpha crystallin family
NIOIMGPL_01014 1.4e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NIOIMGPL_01015 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIOIMGPL_01016 1.8e-34 CP_0960 S Belongs to the UPF0109 family
NIOIMGPL_01017 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NIOIMGPL_01018 2.1e-280 ydfD EK Alanine-glyoxylate amino-transferase
NIOIMGPL_01019 9.3e-82 argO S LysE type translocator
NIOIMGPL_01020 2.8e-221 S Endonuclease/Exonuclease/phosphatase family
NIOIMGPL_01021 6.2e-215 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIOIMGPL_01022 4.2e-164 P Cation efflux family
NIOIMGPL_01023 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIOIMGPL_01024 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
NIOIMGPL_01025 0.0 yjjK S ABC transporter
NIOIMGPL_01026 2e-58 S Protein of unknown function (DUF3039)
NIOIMGPL_01027 1.7e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIOIMGPL_01028 3.6e-107
NIOIMGPL_01029 1e-113 yceD S Uncharacterized ACR, COG1399
NIOIMGPL_01030 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NIOIMGPL_01031 1.8e-139 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIOIMGPL_01032 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
NIOIMGPL_01033 7.6e-92 ilvN 2.2.1.6 E ACT domain
NIOIMGPL_01036 5.7e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIOIMGPL_01037 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NIOIMGPL_01038 8.2e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIOIMGPL_01039 5.4e-173 S Auxin Efflux Carrier
NIOIMGPL_01042 2.2e-141 pgi 5.3.1.9 G Belongs to the GPI family
NIOIMGPL_01043 4.2e-91 L Transposase and inactivated derivatives IS30 family
NIOIMGPL_01044 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
NIOIMGPL_01045 2.2e-41 nrdH O Glutaredoxin
NIOIMGPL_01046 1.5e-98 nrdI F Probably involved in ribonucleotide reductase function
NIOIMGPL_01047 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIOIMGPL_01048 1.2e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIOIMGPL_01049 1.3e-73 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NIOIMGPL_01050 0.0 S Predicted membrane protein (DUF2207)
NIOIMGPL_01051 1e-91 lemA S LemA family
NIOIMGPL_01052 7.2e-116 xylR K purine nucleotide biosynthetic process
NIOIMGPL_01053 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NIOIMGPL_01054 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIOIMGPL_01055 8.9e-119
NIOIMGPL_01056 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
NIOIMGPL_01058 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
NIOIMGPL_01059 3.2e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIOIMGPL_01060 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
NIOIMGPL_01061 7.2e-308 pccB I Carboxyl transferase domain
NIOIMGPL_01062 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NIOIMGPL_01063 2.1e-92 bioY S BioY family
NIOIMGPL_01064 1.3e-151 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
NIOIMGPL_01065 0.0
NIOIMGPL_01066 5.9e-146 QT PucR C-terminal helix-turn-helix domain
NIOIMGPL_01067 1.5e-129 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NIOIMGPL_01068 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NIOIMGPL_01069 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIOIMGPL_01070 6e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIOIMGPL_01071 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIOIMGPL_01072 1.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIOIMGPL_01073 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIOIMGPL_01074 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIOIMGPL_01076 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
NIOIMGPL_01077 3.5e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIOIMGPL_01079 3e-34
NIOIMGPL_01080 0.0 K RNA polymerase II activating transcription factor binding
NIOIMGPL_01081 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NIOIMGPL_01082 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NIOIMGPL_01084 2.7e-100 mntP P Probably functions as a manganese efflux pump
NIOIMGPL_01085 1.4e-125
NIOIMGPL_01086 1.5e-132 KT Transcriptional regulatory protein, C terminal
NIOIMGPL_01087 3e-127 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIOIMGPL_01088 9.6e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
NIOIMGPL_01089 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIOIMGPL_01090 0.0 S domain protein
NIOIMGPL_01091 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
NIOIMGPL_01092 2.4e-90 lrp_3 K helix_turn_helix ASNC type
NIOIMGPL_01093 1.5e-233 E Aminotransferase class I and II
NIOIMGPL_01094 4.3e-305 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NIOIMGPL_01095 8.2e-136 5.4.99.9 H Flavin containing amine oxidoreductase
NIOIMGPL_01096 5e-152 5.4.99.9 H Flavin containing amine oxidoreductase
NIOIMGPL_01097 3.3e-52 S Protein of unknown function (DUF2469)
NIOIMGPL_01098 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
NIOIMGPL_01099 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIOIMGPL_01100 2.4e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIOIMGPL_01101 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIOIMGPL_01102 5.3e-14 V ABC transporter
NIOIMGPL_01103 2.4e-60 V ABC transporter
NIOIMGPL_01104 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
NIOIMGPL_01105 7.7e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIOIMGPL_01106 2.9e-214 rmuC S RmuC family
NIOIMGPL_01107 1.4e-42 csoR S Metal-sensitive transcriptional repressor
NIOIMGPL_01108 0.0 pacS 3.6.3.54 P E1-E2 ATPase
NIOIMGPL_01109 0.0 ubiB S ABC1 family
NIOIMGPL_01110 3.5e-19 S granule-associated protein
NIOIMGPL_01111 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NIOIMGPL_01112 1.3e-274 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
NIOIMGPL_01113 2.2e-257 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NIOIMGPL_01114 1.2e-250 dinF V MatE
NIOIMGPL_01115 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
NIOIMGPL_01116 1e-54 glnB K Nitrogen regulatory protein P-II
NIOIMGPL_01117 3.4e-220 amt U Ammonium Transporter Family
NIOIMGPL_01118 4e-202 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIOIMGPL_01120 7.9e-116 icaR K Bacterial regulatory proteins, tetR family
NIOIMGPL_01121 6.6e-198 XK27_01805 M Glycosyltransferase like family 2
NIOIMGPL_01122 0.0 S Glycosyl hydrolases related to GH101 family, GH129
NIOIMGPL_01123 5.4e-305 pepD E Peptidase family C69
NIOIMGPL_01125 1.1e-91 XK26_04485 P Cobalt transport protein
NIOIMGPL_01126 1.6e-84
NIOIMGPL_01127 0.0 V ABC transporter transmembrane region
NIOIMGPL_01128 2.4e-301 V ABC transporter, ATP-binding protein
NIOIMGPL_01129 2.7e-91 K Winged helix DNA-binding domain
NIOIMGPL_01130 1.2e-302 M LPXTG cell wall anchor motif
NIOIMGPL_01131 3e-196 M chlorophyll binding
NIOIMGPL_01132 4.9e-213 M chlorophyll binding
NIOIMGPL_01133 3.6e-67 3.4.22.70 M Sortase family
NIOIMGPL_01134 1.5e-97 3.4.22.70 M Sortase family
NIOIMGPL_01136 5.1e-09 S Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_01137 2.1e-162 S Sucrose-6F-phosphate phosphohydrolase
NIOIMGPL_01138 2.7e-241 S Putative ABC-transporter type IV
NIOIMGPL_01139 7e-81
NIOIMGPL_01140 4.5e-25 Q phosphatase activity
NIOIMGPL_01141 1e-09 5.2.1.8 S haloacid dehalogenase-like hydrolase
NIOIMGPL_01142 3.4e-293 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
NIOIMGPL_01143 2e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
NIOIMGPL_01144 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NIOIMGPL_01145 2.1e-249 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIOIMGPL_01146 9.3e-68 S haloacid dehalogenase-like hydrolase
NIOIMGPL_01147 3.6e-131 yydK K UTRA
NIOIMGPL_01148 3.8e-70 S FMN_bind
NIOIMGPL_01149 5.7e-149 macB V ABC transporter, ATP-binding protein
NIOIMGPL_01150 3.1e-202 Z012_06715 V FtsX-like permease family
NIOIMGPL_01151 1.1e-221 macB_2 V ABC transporter permease
NIOIMGPL_01152 3.1e-77 S Predicted membrane protein (DUF2318)
NIOIMGPL_01153 3.1e-121 S Predicted membrane protein (DUF2318)
NIOIMGPL_01154 5.4e-108 tpd P Fe2+ transport protein
NIOIMGPL_01155 1.9e-306 efeU_1 P Iron permease FTR1 family
NIOIMGPL_01156 4.5e-22 G MFS/sugar transport protein
NIOIMGPL_01157 2.9e-201 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIOIMGPL_01158 1.8e-37 S Fic/DOC family
NIOIMGPL_01159 6.3e-76 S Fic/DOC family
NIOIMGPL_01160 2.9e-163 L Transposase, Mutator family
NIOIMGPL_01161 1.1e-290 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIOIMGPL_01162 1.9e-37 ptsH G PTS HPr component phosphorylation site
NIOIMGPL_01163 1.7e-199 K helix_turn _helix lactose operon repressor
NIOIMGPL_01164 1.4e-212 holB 2.7.7.7 L DNA polymerase III
NIOIMGPL_01165 1.8e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIOIMGPL_01166 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIOIMGPL_01167 2.5e-159 3.6.1.27 I PAP2 superfamily
NIOIMGPL_01168 3.8e-254 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIOIMGPL_01169 2.6e-100 sixA T Phosphoglycerate mutase family
NIOIMGPL_01170 8.2e-207 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NIOIMGPL_01171 8.8e-178 I alpha/beta hydrolase fold
NIOIMGPL_01172 1.4e-23 rarD S EamA-like transporter family
NIOIMGPL_01173 7.9e-75 rarD 3.4.17.13 E Rard protein
NIOIMGPL_01174 8e-28
NIOIMGPL_01175 3.6e-185 mcrB L Restriction endonuclease
NIOIMGPL_01176 5.6e-10
NIOIMGPL_01177 1.1e-143 O ATPase family associated with various cellular activities (AAA)
NIOIMGPL_01178 1.6e-308 O Subtilase family
NIOIMGPL_01179 7.3e-112 L helicase
NIOIMGPL_01180 4.8e-69 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIOIMGPL_01181 9.6e-163 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
NIOIMGPL_01183 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NIOIMGPL_01184 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NIOIMGPL_01185 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NIOIMGPL_01186 9.8e-277 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIOIMGPL_01187 4.1e-141 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
NIOIMGPL_01188 1.7e-156 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NIOIMGPL_01189 9.6e-180 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIOIMGPL_01190 2.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIOIMGPL_01191 3.3e-57 K MerR family regulatory protein
NIOIMGPL_01192 6.9e-195 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NIOIMGPL_01193 2.6e-136
NIOIMGPL_01194 1.5e-17 K Psort location Cytoplasmic, score
NIOIMGPL_01195 9.1e-16 KLT Protein tyrosine kinase
NIOIMGPL_01196 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIOIMGPL_01197 2.3e-75 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIOIMGPL_01198 2.6e-227 vbsD V MatE
NIOIMGPL_01199 1.6e-131 S Enoyl-(Acyl carrier protein) reductase
NIOIMGPL_01200 2.3e-133 magIII L endonuclease III
NIOIMGPL_01201 1.7e-93 laaE K Transcriptional regulator PadR-like family
NIOIMGPL_01202 1.8e-176 S Membrane transport protein
NIOIMGPL_01203 8.1e-66 4.1.1.44 S Cupin domain
NIOIMGPL_01204 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
NIOIMGPL_01205 3.7e-41 K Helix-turn-helix
NIOIMGPL_01206 1.7e-47 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
NIOIMGPL_01207 3.5e-18
NIOIMGPL_01208 4.2e-101 K Bacterial regulatory proteins, tetR family
NIOIMGPL_01209 4.7e-85 T Domain of unknown function (DUF4234)
NIOIMGPL_01210 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
NIOIMGPL_01211 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIOIMGPL_01212 2.5e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIOIMGPL_01213 2.9e-73 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIOIMGPL_01214 1.2e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
NIOIMGPL_01216 3.7e-287 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
NIOIMGPL_01217 1.1e-22 pafB K WYL domain
NIOIMGPL_01218 4.5e-12
NIOIMGPL_01219 5e-13 S Putative phage holin Dp-1
NIOIMGPL_01220 1.7e-42 M Glycosyl hydrolases family 25
NIOIMGPL_01221 2.3e-29 M Glycosyl hydrolases family 25
NIOIMGPL_01223 1e-17 S Protein of unknown function (DUF2806)
NIOIMGPL_01225 3.5e-119 L Transposase and inactivated derivatives IS30 family
NIOIMGPL_01226 3.6e-67 L Transposase and inactivated derivatives IS30 family
NIOIMGPL_01227 3e-73 comF S competence protein
NIOIMGPL_01228 3.7e-108 dprA LU DNA recombination-mediator protein A
NIOIMGPL_01229 3e-173 int L Phage integrase, N-terminal SAM-like domain
NIOIMGPL_01230 9.3e-31
NIOIMGPL_01231 3.2e-39
NIOIMGPL_01232 5.9e-84
NIOIMGPL_01233 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NIOIMGPL_01235 2.8e-68
NIOIMGPL_01236 7.4e-199 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIOIMGPL_01237 1.4e-144 sufC O FeS assembly ATPase SufC
NIOIMGPL_01238 2.6e-233 sufD O FeS assembly protein SufD
NIOIMGPL_01239 2.5e-211 sufB O FeS assembly protein SufB
NIOIMGPL_01240 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIOIMGPL_01241 6.8e-08 3.4.22.70 M Sortase family
NIOIMGPL_01242 2e-108 K helix_turn_helix, Lux Regulon
NIOIMGPL_01243 1.4e-16
NIOIMGPL_01244 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NIOIMGPL_01245 2.7e-140 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NIOIMGPL_01246 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NIOIMGPL_01247 2.2e-47 3.4.23.43 S Type IV leader peptidase family
NIOIMGPL_01248 4.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIOIMGPL_01249 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIOIMGPL_01250 1.2e-250 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIOIMGPL_01251 8.4e-70 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIOIMGPL_01252 3.3e-97 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIOIMGPL_01253 1.1e-36
NIOIMGPL_01254 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
NIOIMGPL_01255 1.9e-135 pgm3 G Phosphoglycerate mutase family
NIOIMGPL_01256 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
NIOIMGPL_01257 1.4e-96 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIOIMGPL_01258 1.3e-127 lolD V ABC transporter
NIOIMGPL_01259 1.9e-212 V FtsX-like permease family
NIOIMGPL_01260 8.2e-64 S Domain of unknown function (DUF4418)
NIOIMGPL_01261 0.0 pcrA 3.6.4.12 L DNA helicase
NIOIMGPL_01262 7.8e-199 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
NIOIMGPL_01263 1.3e-111 yrhL I Psort location CytoplasmicMembrane, score 9.99
NIOIMGPL_01264 8.7e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIOIMGPL_01265 3.1e-41 pbuX F Permease family
NIOIMGPL_01266 6.8e-176 pbuX F Permease family
NIOIMGPL_01268 1.4e-11 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIOIMGPL_01269 2e-17 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIOIMGPL_01270 6.7e-90 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIOIMGPL_01272 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
NIOIMGPL_01273 9e-40
NIOIMGPL_01274 1.7e-27 2.1.1.72 S Adenine-specific methyltransferase EcoRI
NIOIMGPL_01275 4.7e-119 tnp7109-21 L Integrase core domain
NIOIMGPL_01276 1.9e-47 L Transposase
NIOIMGPL_01277 1.3e-63 D MobA/MobL family
NIOIMGPL_01278 1.9e-65
NIOIMGPL_01280 1.4e-79 L Transposase and inactivated derivatives IS30 family
NIOIMGPL_01281 4.6e-94 L Transposase and inactivated derivatives IS30 family
NIOIMGPL_01282 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NIOIMGPL_01283 2.7e-45 V ABC-2 family transporter protein
NIOIMGPL_01284 6.7e-194 V ABC-2 family transporter protein
NIOIMGPL_01285 3.8e-224 V ABC-2 family transporter protein
NIOIMGPL_01286 4.1e-127 V ATPases associated with a variety of cellular activities
NIOIMGPL_01287 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NIOIMGPL_01288 3.2e-234 T Histidine kinase
NIOIMGPL_01289 6.3e-120 K helix_turn_helix, Lux Regulon
NIOIMGPL_01290 1.1e-115 MA20_27875 P Protein of unknown function DUF47
NIOIMGPL_01291 3.4e-189 pit P Phosphate transporter family
NIOIMGPL_01292 1.3e-81 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NIOIMGPL_01293 4.1e-169 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NIOIMGPL_01294 1e-109 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NIOIMGPL_01295 2.3e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NIOIMGPL_01296 1e-24
NIOIMGPL_01297 8.2e-185
NIOIMGPL_01298 1.1e-30 L Transposase
NIOIMGPL_01299 3e-69 L Integrase core domain
NIOIMGPL_01301 8.7e-21 S Psort location Cytoplasmic, score 8.96
NIOIMGPL_01302 1.1e-150 S Protein of unknown function (DUF1524)
NIOIMGPL_01303 3.7e-117 S Protein of unknown function (DUF3800)
NIOIMGPL_01304 1.1e-42 tnp7109-21 L Integrase core domain
NIOIMGPL_01305 2.4e-43 L IstB-like ATP binding protein
NIOIMGPL_01306 1.7e-36 L Transposase
NIOIMGPL_01307 2e-73 I Sterol carrier protein
NIOIMGPL_01308 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NIOIMGPL_01309 3.4e-35
NIOIMGPL_01310 7.1e-144 gluP 3.4.21.105 S Rhomboid family
NIOIMGPL_01311 6.9e-93 L HTH-like domain
NIOIMGPL_01312 6.1e-257 L ribosomal rna small subunit methyltransferase
NIOIMGPL_01313 6.9e-67 crgA D Involved in cell division
NIOIMGPL_01314 3.5e-143 S Bacterial protein of unknown function (DUF881)
NIOIMGPL_01315 1.7e-232 srtA 3.4.22.70 M Sortase family
NIOIMGPL_01316 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
NIOIMGPL_01317 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
NIOIMGPL_01318 2e-183 T Protein tyrosine kinase
NIOIMGPL_01319 4.8e-263 pbpA M penicillin-binding protein
NIOIMGPL_01320 2.8e-266 rodA D Belongs to the SEDS family
NIOIMGPL_01321 3.7e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
NIOIMGPL_01322 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
NIOIMGPL_01323 1e-130 fhaA T Protein of unknown function (DUF2662)
NIOIMGPL_01324 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
NIOIMGPL_01325 0.0 pip S YhgE Pip domain protein
NIOIMGPL_01326 0.0 pip S YhgE Pip domain protein
NIOIMGPL_01327 3.9e-206 pldB 3.1.1.5 I Serine aminopeptidase, S33
NIOIMGPL_01328 2e-164 yicL EG EamA-like transporter family
NIOIMGPL_01329 2.6e-103
NIOIMGPL_01331 2.1e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIOIMGPL_01333 0.0 KL Domain of unknown function (DUF3427)
NIOIMGPL_01334 2.5e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NIOIMGPL_01335 1.3e-40 D DivIVA domain protein
NIOIMGPL_01336 9.3e-53 ybjQ S Putative heavy-metal-binding
NIOIMGPL_01337 6e-154 I Serine aminopeptidase, S33
NIOIMGPL_01338 6.3e-87 yjcF Q Acetyltransferase (GNAT) domain
NIOIMGPL_01340 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NIOIMGPL_01341 1.7e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
NIOIMGPL_01342 0.0 cadA P E1-E2 ATPase
NIOIMGPL_01343 1.9e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
NIOIMGPL_01344 6.9e-170 htpX O Belongs to the peptidase M48B family
NIOIMGPL_01349 4e-126 3.5.1.28 M NLP P60 protein
NIOIMGPL_01350 6.5e-67 S SPP1 phage holin
NIOIMGPL_01352 3e-69
NIOIMGPL_01353 8.4e-26 L DNA integration
NIOIMGPL_01354 2.5e-86
NIOIMGPL_01355 2.5e-117
NIOIMGPL_01356 1.6e-28
NIOIMGPL_01357 9.4e-16
NIOIMGPL_01358 1.9e-185 S Helix-turn-helix domain
NIOIMGPL_01359 9.6e-42
NIOIMGPL_01360 2.6e-91 S Transcription factor WhiB
NIOIMGPL_01361 8.2e-117 parA D AAA domain
NIOIMGPL_01362 0.0 topB 5.99.1.2 L DNA topoisomerase
NIOIMGPL_01363 1.1e-81
NIOIMGPL_01364 4.4e-60
NIOIMGPL_01365 4.6e-45
NIOIMGPL_01366 3.8e-167 S HipA-like C-terminal domain
NIOIMGPL_01367 3.5e-171 dapE 3.5.1.18 E Peptidase dimerisation domain
NIOIMGPL_01368 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
NIOIMGPL_01369 3.3e-256 V Efflux ABC transporter, permease protein
NIOIMGPL_01370 1.7e-162 V ATPases associated with a variety of cellular activities
NIOIMGPL_01371 2.6e-56
NIOIMGPL_01372 2.7e-64
NIOIMGPL_01373 1.2e-277 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
NIOIMGPL_01374 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIOIMGPL_01375 5.7e-239 hom 1.1.1.3 E Homoserine dehydrogenase
NIOIMGPL_01376 8.4e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
NIOIMGPL_01377 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIOIMGPL_01378 5.7e-305 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIOIMGPL_01379 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NIOIMGPL_01380 6.8e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NIOIMGPL_01381 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
NIOIMGPL_01382 2.2e-156 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_01383 7.2e-28 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_01384 1.1e-89 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
NIOIMGPL_01386 5.6e-152 IQ KR domain
NIOIMGPL_01387 1.4e-37 4.2.1.68 M Enolase C-terminal domain-like
NIOIMGPL_01388 1.6e-17 4.2.1.68 M carboxylic acid catabolic process
NIOIMGPL_01389 1.4e-184 K Bacterial regulatory proteins, lacI family
NIOIMGPL_01391 2.4e-118 cyaA 4.6.1.1 S CYTH
NIOIMGPL_01392 5.5e-162 trxA2 O Tetratricopeptide repeat
NIOIMGPL_01393 7.9e-180
NIOIMGPL_01394 2.2e-188
NIOIMGPL_01395 9.8e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
NIOIMGPL_01396 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIOIMGPL_01397 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIOIMGPL_01398 2.5e-132
NIOIMGPL_01399 2.1e-131 K Bacterial regulatory proteins, tetR family
NIOIMGPL_01400 1.6e-223 G Transmembrane secretion effector
NIOIMGPL_01401 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIOIMGPL_01402 1.4e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
NIOIMGPL_01403 5.1e-180 S CAAX protease self-immunity
NIOIMGPL_01405 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
NIOIMGPL_01406 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIOIMGPL_01407 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIOIMGPL_01408 2.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
NIOIMGPL_01409 5.8e-252 S Calcineurin-like phosphoesterase
NIOIMGPL_01412 1.6e-64 S Domain of unknown function (DUF4143)
NIOIMGPL_01413 8.4e-88 S Domain of unknown function (DUF4143)
NIOIMGPL_01414 2.9e-276 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIOIMGPL_01416 1.2e-120 S HAD hydrolase, family IA, variant 3
NIOIMGPL_01417 8.6e-201 P NMT1/THI5 like
NIOIMGPL_01418 5.8e-138 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
NIOIMGPL_01419 1.2e-142
NIOIMGPL_01420 1.1e-124 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
NIOIMGPL_01421 1.1e-262 EGP Major facilitator Superfamily
NIOIMGPL_01422 2.6e-97 S GtrA-like protein
NIOIMGPL_01423 1.1e-61 S Macrophage migration inhibitory factor (MIF)
NIOIMGPL_01424 5.5e-286 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
NIOIMGPL_01425 0.0 pepD E Peptidase family C69
NIOIMGPL_01426 1.3e-107 S Phosphatidylethanolamine-binding protein
NIOIMGPL_01427 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
NIOIMGPL_01428 1.9e-196 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
NIOIMGPL_01429 0.0 lmrA2 V ABC transporter transmembrane region
NIOIMGPL_01430 0.0 lmrA1 V ABC transporter, ATP-binding protein
NIOIMGPL_01431 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
NIOIMGPL_01432 6.4e-42 S Protein of unknown function (DUF1778)
NIOIMGPL_01433 3.7e-190 1.1.1.65 C Aldo/keto reductase family
NIOIMGPL_01434 9.1e-36 M F5/8 type C domain
NIOIMGPL_01435 8.9e-53
NIOIMGPL_01437 1.3e-111 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
NIOIMGPL_01438 3e-113 K WHG domain
NIOIMGPL_01439 2e-32 1.3.3.6, 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
NIOIMGPL_01440 8.5e-266 EGP Major Facilitator Superfamily
NIOIMGPL_01441 3.5e-302 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NIOIMGPL_01442 6.7e-150 L HNH endonuclease
NIOIMGPL_01443 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NIOIMGPL_01444 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIOIMGPL_01445 1.5e-23 L Transposase
NIOIMGPL_01446 4.9e-86 L Transposase
NIOIMGPL_01447 2.8e-72 S AIPR protein
NIOIMGPL_01448 2.1e-41 XAC3035 O Glutaredoxin
NIOIMGPL_01449 8.9e-149 S Virulence factor BrkB
NIOIMGPL_01450 1.9e-98 bcp 1.11.1.15 O Redoxin
NIOIMGPL_01451 2.9e-38 E ABC transporter
NIOIMGPL_01452 5.1e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIOIMGPL_01453 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIOIMGPL_01454 0.0 V FtsX-like permease family
NIOIMGPL_01455 7.5e-129 V ABC transporter
NIOIMGPL_01456 7e-101 K Transcriptional regulator C-terminal region
NIOIMGPL_01457 1.3e-274 aroP E aromatic amino acid transport protein AroP K03293
NIOIMGPL_01458 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NIOIMGPL_01459 2.6e-183 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
NIOIMGPL_01460 4e-83 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)