ORF_ID e_value Gene_name EC_number CAZy COGs Description
AHPHCOMF_00001 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AHPHCOMF_00002 1.6e-10
AHPHCOMF_00003 9e-98 K Transcriptional regulator, TetR family
AHPHCOMF_00004 1.8e-159 czcD P cation diffusion facilitator family transporter
AHPHCOMF_00005 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AHPHCOMF_00006 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
AHPHCOMF_00007 6e-08 S Hydrolases of the alpha beta superfamily
AHPHCOMF_00008 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
AHPHCOMF_00009 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
AHPHCOMF_00012 2.6e-143 2.4.2.3 F Phosphorylase superfamily
AHPHCOMF_00013 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
AHPHCOMF_00014 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
AHPHCOMF_00015 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
AHPHCOMF_00016 3.9e-15 dinF V Mate efflux family protein
AHPHCOMF_00018 2.1e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
AHPHCOMF_00019 3.7e-190
AHPHCOMF_00020 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
AHPHCOMF_00021 3.5e-28 3.4.13.21 I Protein conserved in bacteria
AHPHCOMF_00023 3.7e-117 S TraX protein
AHPHCOMF_00024 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
AHPHCOMF_00025 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
AHPHCOMF_00026 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AHPHCOMF_00027 1.2e-180 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_00028 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_00029 6.8e-133 cas6 S Pfam:DUF2276
AHPHCOMF_00030 0.0 csm1 S CRISPR-associated protein Csm1 family
AHPHCOMF_00031 5.6e-62 csm2 L Pfam:DUF310
AHPHCOMF_00032 1.1e-116 csm3 L RAMP superfamily
AHPHCOMF_00033 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
AHPHCOMF_00034 2.2e-204 csm5 L CRISPR-associated RAMP protein, Csm5 family
AHPHCOMF_00035 2.1e-14 csm6 S Psort location Cytoplasmic, score
AHPHCOMF_00036 5.2e-74 csm6 S Psort location Cytoplasmic, score
AHPHCOMF_00037 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AHPHCOMF_00038 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AHPHCOMF_00039 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
AHPHCOMF_00041 1.1e-267 dtpT E transporter
AHPHCOMF_00042 8.5e-103 nylA 3.5.1.4 J Belongs to the amidase family
AHPHCOMF_00043 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
AHPHCOMF_00044 1.8e-67 yecS P ABC transporter (Permease
AHPHCOMF_00046 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
AHPHCOMF_00047 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
AHPHCOMF_00048 1.4e-104 yfiF3 K sequence-specific DNA binding
AHPHCOMF_00049 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AHPHCOMF_00050 1.8e-240 agcS E (Alanine) symporter
AHPHCOMF_00051 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AHPHCOMF_00052 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
AHPHCOMF_00053 1.8e-59 Q phosphatase activity
AHPHCOMF_00054 9.3e-62 S haloacid dehalogenase-like hydrolase
AHPHCOMF_00055 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AHPHCOMF_00056 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
AHPHCOMF_00057 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
AHPHCOMF_00058 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
AHPHCOMF_00059 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AHPHCOMF_00060 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AHPHCOMF_00061 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AHPHCOMF_00062 1.9e-43 yktA S Belongs to the UPF0223 family
AHPHCOMF_00063 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AHPHCOMF_00064 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
AHPHCOMF_00065 3.3e-158 pstS P phosphate
AHPHCOMF_00066 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
AHPHCOMF_00067 1.2e-155 pstA P phosphate transport system permease
AHPHCOMF_00068 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AHPHCOMF_00069 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AHPHCOMF_00070 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
AHPHCOMF_00071 0.0 pepN 3.4.11.2 E aminopeptidase
AHPHCOMF_00072 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
AHPHCOMF_00073 1.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
AHPHCOMF_00076 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AHPHCOMF_00077 1.2e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
AHPHCOMF_00078 2.3e-23 L Transposase
AHPHCOMF_00079 4.6e-25 tatA U protein secretion
AHPHCOMF_00080 2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AHPHCOMF_00081 3.5e-297 ywbL P COG0672 High-affinity Fe2 Pb2 permease
AHPHCOMF_00082 1.6e-232 ycdB P peroxidase
AHPHCOMF_00083 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
AHPHCOMF_00084 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
AHPHCOMF_00085 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
AHPHCOMF_00086 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHPHCOMF_00087 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHPHCOMF_00088 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00089 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00090 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00091 6.1e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00092 4.4e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00093 1.9e-37 3.5.1.28 NU amidase activity
AHPHCOMF_00094 8.5e-266 3.5.1.28 NU amidase activity
AHPHCOMF_00095 1.6e-83 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
AHPHCOMF_00096 0.0 lpdA 1.8.1.4 C Dehydrogenase
AHPHCOMF_00097 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AHPHCOMF_00098 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AHPHCOMF_00099 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
AHPHCOMF_00100 5e-38 P membrane protein (DUF2207)
AHPHCOMF_00101 1.8e-64 S the current gene model (or a revised gene model) may contain a frame shift
AHPHCOMF_00102 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AHPHCOMF_00103 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AHPHCOMF_00104 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AHPHCOMF_00105 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
AHPHCOMF_00106 3.4e-22 3.4.16.4 M Belongs to the peptidase S11 family
AHPHCOMF_00107 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
AHPHCOMF_00108 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
AHPHCOMF_00109 1.2e-157 rssA S Phospholipase, patatin family
AHPHCOMF_00110 3.9e-78 estA E GDSL-like protein
AHPHCOMF_00111 2.6e-15 estA E Lysophospholipase L1 and related esterases
AHPHCOMF_00112 5.3e-292 S unusual protein kinase
AHPHCOMF_00113 4.9e-39 S granule-associated protein
AHPHCOMF_00114 4.6e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AHPHCOMF_00115 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AHPHCOMF_00116 1.3e-199 S hmm pf01594
AHPHCOMF_00117 1.1e-87 G Belongs to the phosphoglycerate mutase family
AHPHCOMF_00118 8.4e-69 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
AHPHCOMF_00119 9.2e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
AHPHCOMF_00120 5.8e-95 V VanZ like family
AHPHCOMF_00121 5.5e-178 L Transposase
AHPHCOMF_00122 5.6e-20 rmlC 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
AHPHCOMF_00123 2.7e-160 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AHPHCOMF_00124 7.3e-248 cps1C S Polysaccharide biosynthesis protein
AHPHCOMF_00125 1.2e-141 cps1B GT2,GT4 M Glycosyl transferases group 1
AHPHCOMF_00126 1.7e-36 S Psort location CytoplasmicMembrane, score 9.99
AHPHCOMF_00127 2.9e-80 sacB GT2,GT4 M transferase activity, transferring glycosyl groups
AHPHCOMF_00128 4.9e-68 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
AHPHCOMF_00129 1.1e-149 M Glycosyltransferase, group 2 family protein
AHPHCOMF_00130 8.5e-87 Z012_10770 M Domain of unknown function (DUF1919)
AHPHCOMF_00131 1.1e-209 wcoF M Glycosyltransferase, group 1 family protein
AHPHCOMF_00132 4.5e-219 rgpAc GT4 M group 1 family protein
AHPHCOMF_00133 2.7e-255 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
AHPHCOMF_00134 1.1e-117 cpsD D COG0489 ATPases involved in chromosome partitioning
AHPHCOMF_00135 4.7e-107 cps4C M biosynthesis protein
AHPHCOMF_00136 1.1e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
AHPHCOMF_00137 1.5e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
AHPHCOMF_00138 5.8e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
AHPHCOMF_00139 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
AHPHCOMF_00140 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
AHPHCOMF_00141 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AHPHCOMF_00142 9.3e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
AHPHCOMF_00143 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AHPHCOMF_00145 6.1e-22 V Glucan-binding protein C
AHPHCOMF_00146 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
AHPHCOMF_00147 9e-275 pepV 3.5.1.18 E Dipeptidase
AHPHCOMF_00148 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AHPHCOMF_00149 2e-85 XK27_03610 K Gnat family
AHPHCOMF_00150 9.1e-10 L COG1943 Transposase and inactivated derivatives
AHPHCOMF_00151 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AHPHCOMF_00152 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AHPHCOMF_00153 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AHPHCOMF_00154 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AHPHCOMF_00155 2.8e-18 M LysM domain
AHPHCOMF_00156 2.9e-90 ebsA S Family of unknown function (DUF5322)
AHPHCOMF_00157 1.1e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AHPHCOMF_00158 1.8e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AHPHCOMF_00159 2.4e-223 G COG0457 FOG TPR repeat
AHPHCOMF_00160 6.2e-176 yubA S permease
AHPHCOMF_00161 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
AHPHCOMF_00162 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
AHPHCOMF_00163 2.5e-124 ftsE D cell division ATP-binding protein FtsE
AHPHCOMF_00164 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AHPHCOMF_00165 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AHPHCOMF_00166 1.3e-181 yjjH S Calcineurin-like phosphoesterase
AHPHCOMF_00167 1.5e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AHPHCOMF_00168 0.0 pacL 3.6.3.8 P cation transport ATPase
AHPHCOMF_00169 2.6e-67 ywiB S Domain of unknown function (DUF1934)
AHPHCOMF_00170 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
AHPHCOMF_00171 9.2e-147 yidA S hydrolases of the HAD superfamily
AHPHCOMF_00172 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
AHPHCOMF_00173 5e-35 F Protein of unknown function (DUF454)
AHPHCOMF_00174 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
AHPHCOMF_00175 1.4e-245 vicK 2.7.13.3 T Histidine kinase
AHPHCOMF_00176 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_00177 3.3e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
AHPHCOMF_00178 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AHPHCOMF_00179 8e-115 gltJ P ABC transporter (Permease
AHPHCOMF_00180 2.5e-110 tcyB_2 P ABC transporter (permease)
AHPHCOMF_00181 3.5e-123 endA F DNA RNA non-specific endonuclease
AHPHCOMF_00182 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
AHPHCOMF_00183 9.4e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AHPHCOMF_00185 1.9e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AHPHCOMF_00186 3.5e-26 G Domain of unknown function (DUF4832)
AHPHCOMF_00187 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AHPHCOMF_00188 1.2e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AHPHCOMF_00189 4.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AHPHCOMF_00190 6.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
AHPHCOMF_00191 1.3e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AHPHCOMF_00192 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
AHPHCOMF_00195 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AHPHCOMF_00196 3.2e-220 XK27_05110 P chloride
AHPHCOMF_00197 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
AHPHCOMF_00198 3.7e-282 clcA P Chloride transporter, ClC family
AHPHCOMF_00199 2.3e-75 fld C Flavodoxin
AHPHCOMF_00200 3.3e-14 XK27_08880
AHPHCOMF_00201 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
AHPHCOMF_00202 3.5e-151 estA CE1 S Putative esterase
AHPHCOMF_00203 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AHPHCOMF_00204 1.2e-135 XK27_08845 S abc transporter atp-binding protein
AHPHCOMF_00205 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_00206 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
AHPHCOMF_00207 1.6e-16 S Domain of unknown function (DUF4649)
AHPHCOMF_00209 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
AHPHCOMF_00210 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
AHPHCOMF_00213 3.9e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AHPHCOMF_00214 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AHPHCOMF_00215 0.0 dnaE 2.7.7.7 L DNA polymerase
AHPHCOMF_00216 4.1e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
AHPHCOMF_00217 1.2e-111 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AHPHCOMF_00218 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AHPHCOMF_00219 3.3e-43 ysdA L Membrane
AHPHCOMF_00220 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AHPHCOMF_00221 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHPHCOMF_00222 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AHPHCOMF_00223 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
AHPHCOMF_00225 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AHPHCOMF_00226 2.1e-84 ypmS S Protein conserved in bacteria
AHPHCOMF_00227 6e-144 ypmR E lipolytic protein G-D-S-L family
AHPHCOMF_00228 1e-148 DegV S DegV family
AHPHCOMF_00229 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
AHPHCOMF_00230 1.8e-72 argR K Regulates arginine biosynthesis genes
AHPHCOMF_00231 4.3e-158 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AHPHCOMF_00232 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AHPHCOMF_00233 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
AHPHCOMF_00234 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AHPHCOMF_00237 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AHPHCOMF_00238 2.9e-125 dnaD
AHPHCOMF_00239 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AHPHCOMF_00240 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AHPHCOMF_00241 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
AHPHCOMF_00242 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AHPHCOMF_00243 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AHPHCOMF_00244 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
AHPHCOMF_00245 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AHPHCOMF_00246 5.6e-240 rodA D Belongs to the SEDS family
AHPHCOMF_00247 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
AHPHCOMF_00248 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AHPHCOMF_00249 5.8e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AHPHCOMF_00250 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AHPHCOMF_00251 6.3e-108 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AHPHCOMF_00252 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
AHPHCOMF_00253 1.2e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AHPHCOMF_00254 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AHPHCOMF_00255 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AHPHCOMF_00256 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AHPHCOMF_00258 6.6e-31 L Integrase core domain protein
AHPHCOMF_00259 1.6e-55 L transposition
AHPHCOMF_00260 8.2e-22 L Transposase
AHPHCOMF_00261 5.2e-36 L transposase activity
AHPHCOMF_00262 1.3e-22 XK27_08085
AHPHCOMF_00263 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
AHPHCOMF_00264 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
AHPHCOMF_00265 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
AHPHCOMF_00266 1.1e-121 ylfI S tigr01906
AHPHCOMF_00267 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AHPHCOMF_00268 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
AHPHCOMF_00269 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
AHPHCOMF_00272 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AHPHCOMF_00273 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AHPHCOMF_00274 4.1e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AHPHCOMF_00275 1.1e-206 yurR 1.4.5.1 E oxidoreductase
AHPHCOMF_00276 6.3e-101 zupT P Mediates zinc uptake. May also transport other divalent cations
AHPHCOMF_00277 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AHPHCOMF_00278 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
AHPHCOMF_00279 1.7e-70 gtrA S GtrA-like protein
AHPHCOMF_00280 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AHPHCOMF_00281 6e-169 ybbR S Protein conserved in bacteria
AHPHCOMF_00282 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AHPHCOMF_00283 1.8e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
AHPHCOMF_00284 8.7e-150 cobQ S glutamine amidotransferase
AHPHCOMF_00285 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AHPHCOMF_00286 1.4e-130 pip 1.11.1.10 S Alpha beta hydrolase
AHPHCOMF_00288 0.0 uup S abc transporter atp-binding protein
AHPHCOMF_00289 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
AHPHCOMF_00290 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
AHPHCOMF_00291 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AHPHCOMF_00292 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
AHPHCOMF_00293 1.6e-249 L Transposase
AHPHCOMF_00294 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AHPHCOMF_00295 7.9e-39 ptsH G phosphocarrier protein Hpr
AHPHCOMF_00296 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
AHPHCOMF_00297 4.3e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
AHPHCOMF_00298 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AHPHCOMF_00299 8.5e-34 nrdH O Glutaredoxin
AHPHCOMF_00300 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHPHCOMF_00301 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHPHCOMF_00303 1.9e-71 L Transposase (IS116 IS110 IS902 family)
AHPHCOMF_00304 3.6e-61 L Transposase (IS116 IS110 IS902 family)
AHPHCOMF_00305 6.9e-165 ypuA S secreted protein
AHPHCOMF_00306 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
AHPHCOMF_00307 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
AHPHCOMF_00308 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AHPHCOMF_00309 7e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AHPHCOMF_00310 2.6e-258 noxE P NADH oxidase
AHPHCOMF_00311 9.5e-294 yfmM S abc transporter atp-binding protein
AHPHCOMF_00312 6.7e-83 XK27_01265 S ECF-type riboflavin transporter, S component
AHPHCOMF_00313 3.5e-86 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
AHPHCOMF_00314 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
AHPHCOMF_00315 2e-86 S ECF-type riboflavin transporter, S component
AHPHCOMF_00317 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AHPHCOMF_00318 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
AHPHCOMF_00321 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AHPHCOMF_00322 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AHPHCOMF_00323 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AHPHCOMF_00324 0.0 smc D Required for chromosome condensation and partitioning
AHPHCOMF_00325 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AHPHCOMF_00326 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHPHCOMF_00327 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AHPHCOMF_00328 2.4e-92 pat 2.3.1.183 M acetyltransferase
AHPHCOMF_00329 1.1e-12
AHPHCOMF_00330 3.4e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AHPHCOMF_00331 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AHPHCOMF_00332 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
AHPHCOMF_00333 1.2e-62 bioY S biotin transmembrane transporter activity
AHPHCOMF_00334 2e-88 proW P Binding-protein-dependent transport system inner membrane component
AHPHCOMF_00335 1.6e-137 proV E abc transporter atp-binding protein
AHPHCOMF_00336 3.8e-165 proX M ABC transporter, substrate-binding protein, QAT family
AHPHCOMF_00337 2.3e-103 proWZ P ABC transporter (Permease
AHPHCOMF_00338 2.5e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
AHPHCOMF_00339 1.6e-205 S Protein of unknown function (DUF917)
AHPHCOMF_00340 2.5e-308 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AHPHCOMF_00341 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
AHPHCOMF_00342 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AHPHCOMF_00343 1.5e-184 desK 2.7.13.3 T Histidine kinase
AHPHCOMF_00344 1.2e-132 yvfS V ABC-2 type transporter
AHPHCOMF_00345 5.3e-156 XK27_09825 V abc transporter atp-binding protein
AHPHCOMF_00349 6.6e-213 EGP Major facilitator Superfamily
AHPHCOMF_00350 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
AHPHCOMF_00351 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_00352 4.6e-42 3.6.1.55 F NUDIX domain
AHPHCOMF_00354 3.7e-122 S An automated process has identified a potential problem with this gene model
AHPHCOMF_00355 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
AHPHCOMF_00356 1.4e-15 liaI KT membrane
AHPHCOMF_00357 2.6e-30 liaI KT membrane
AHPHCOMF_00358 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
AHPHCOMF_00359 0.0 V ABC transporter (permease)
AHPHCOMF_00360 1.9e-133 macB2 V ABC transporter, ATP-binding protein
AHPHCOMF_00361 9e-165 T Histidine kinase
AHPHCOMF_00362 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_00363 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AHPHCOMF_00364 3.3e-69 pbuX F xanthine permease
AHPHCOMF_00365 9.2e-119 pbuX F xanthine permease
AHPHCOMF_00366 4.5e-247 norM V Multidrug efflux pump
AHPHCOMF_00367 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHPHCOMF_00368 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
AHPHCOMF_00369 1.9e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
AHPHCOMF_00370 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
AHPHCOMF_00371 4.8e-25 csbD K CsbD-like
AHPHCOMF_00372 6.2e-228 yfnA E amino acid
AHPHCOMF_00373 5.7e-109 XK27_02070 S nitroreductase
AHPHCOMF_00374 1.2e-138 1.13.11.2 S glyoxalase
AHPHCOMF_00375 5.6e-77 ywnA K Transcriptional regulator
AHPHCOMF_00376 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
AHPHCOMF_00377 1.1e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AHPHCOMF_00378 2.2e-111 drgA C Nitroreductase
AHPHCOMF_00379 4.2e-96 yoaK S Protein of unknown function (DUF1275)
AHPHCOMF_00380 1.5e-160 yvgN C reductase
AHPHCOMF_00381 1e-181 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AHPHCOMF_00382 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
AHPHCOMF_00384 1.1e-37 BP1961 P nitric oxide dioxygenase activity
AHPHCOMF_00385 1.8e-54 K response regulator
AHPHCOMF_00386 7.4e-31 S Signal peptide protein, YSIRK family
AHPHCOMF_00388 1.6e-58
AHPHCOMF_00389 1.3e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHPHCOMF_00390 1.9e-35
AHPHCOMF_00391 4e-20
AHPHCOMF_00392 3.3e-24 IQ PFAM AMP-dependent synthetase and ligase
AHPHCOMF_00393 2.7e-26 IQ PFAM AMP-dependent synthetase and ligase
AHPHCOMF_00394 5.8e-109 MA20_06410 E LysE type translocator
AHPHCOMF_00395 5.6e-08
AHPHCOMF_00396 2.7e-09
AHPHCOMF_00397 0.0 M family 8
AHPHCOMF_00400 1.5e-162 hrtB V MacB-like periplasmic core domain
AHPHCOMF_00401 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
AHPHCOMF_00402 1.1e-151 V MatE
AHPHCOMF_00404 1.5e-109 C Fe-S oxidoreductases
AHPHCOMF_00405 1.2e-176 EGP Major Facilitator Superfamily
AHPHCOMF_00406 5.5e-258 I radical SAM domain protein
AHPHCOMF_00408 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_00409 1.4e-150 L Integrase core domain protein
AHPHCOMF_00410 1.8e-87 L transposase activity
AHPHCOMF_00412 2.8e-85
AHPHCOMF_00413 0.0 sbcC L ATPase involved in DNA repair
AHPHCOMF_00414 2e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AHPHCOMF_00415 0.0 lacL 3.2.1.23 G -beta-galactosidase
AHPHCOMF_00416 0.0 lacS G transporter
AHPHCOMF_00417 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AHPHCOMF_00418 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AHPHCOMF_00419 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
AHPHCOMF_00420 1.8e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AHPHCOMF_00421 2.3e-184 galR K Transcriptional regulator
AHPHCOMF_00422 2.7e-08 L Integrase core domain protein
AHPHCOMF_00423 1.2e-25 L transposition
AHPHCOMF_00424 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
AHPHCOMF_00425 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
AHPHCOMF_00426 2.5e-101 V abc transporter atp-binding protein
AHPHCOMF_00427 4.3e-40 V abc transporter atp-binding protein
AHPHCOMF_00428 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
AHPHCOMF_00429 6.4e-62 L Transposase
AHPHCOMF_00430 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00431 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00432 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00433 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AHPHCOMF_00434 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AHPHCOMF_00435 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AHPHCOMF_00436 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AHPHCOMF_00439 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AHPHCOMF_00440 5.8e-175 vraS 2.7.13.3 T Histidine kinase
AHPHCOMF_00441 3.7e-120 yvqF KT membrane
AHPHCOMF_00442 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
AHPHCOMF_00443 2e-132 stp 3.1.3.16 T phosphatase
AHPHCOMF_00444 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AHPHCOMF_00445 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AHPHCOMF_00446 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AHPHCOMF_00447 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
AHPHCOMF_00448 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AHPHCOMF_00449 6.7e-214 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AHPHCOMF_00450 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
AHPHCOMF_00451 8.2e-148 supH S overlaps another CDS with the same product name
AHPHCOMF_00452 8.6e-63 yvoA_1 K Transcriptional
AHPHCOMF_00453 4.9e-120 skfE V abc transporter atp-binding protein
AHPHCOMF_00454 5.6e-133 V ATPase activity
AHPHCOMF_00455 3.6e-171 oppF P Belongs to the ABC transporter superfamily
AHPHCOMF_00456 6.4e-204 oppD P Belongs to the ABC transporter superfamily
AHPHCOMF_00457 2.4e-167 amiD P ABC transporter (Permease
AHPHCOMF_00458 1.1e-270 amiC P ABC transporter (Permease
AHPHCOMF_00459 0.0 amiA E ABC transporter, substrate-binding protein, family 5
AHPHCOMF_00460 1.2e-24 oppF P Belongs to the ABC transporter superfamily
AHPHCOMF_00461 3.5e-24 oppF P Belongs to the ABC transporter superfamily
AHPHCOMF_00462 8.9e-40 tatD L Hydrolase, tatd
AHPHCOMF_00463 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
AHPHCOMF_00464 2.1e-85 L Integrase core domain protein
AHPHCOMF_00465 1.9e-78 L Transposase
AHPHCOMF_00466 3.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AHPHCOMF_00467 8.3e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AHPHCOMF_00468 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AHPHCOMF_00469 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
AHPHCOMF_00470 1.5e-103 yjbK S Adenylate cyclase
AHPHCOMF_00471 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AHPHCOMF_00472 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
AHPHCOMF_00473 3.1e-59 XK27_04120 S Putative amino acid metabolism
AHPHCOMF_00474 1.1e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AHPHCOMF_00475 4.8e-128 puuD T peptidase C26
AHPHCOMF_00476 1.2e-115 radC E Belongs to the UPF0758 family
AHPHCOMF_00477 1.7e-268 M Psort location CytoplasmicMembrane, score
AHPHCOMF_00478 0.0 rgpF M Rhamnan synthesis protein F
AHPHCOMF_00479 4.5e-305 GT4 M transferase activity, transferring glycosyl groups
AHPHCOMF_00480 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AHPHCOMF_00481 1.8e-142 rgpC GM Transport permease protein
AHPHCOMF_00482 6.4e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
AHPHCOMF_00483 2.3e-228 rgpA GT4 M Domain of unknown function (DUF1972)
AHPHCOMF_00484 2.4e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
AHPHCOMF_00485 4.6e-42 S Uncharacterized conserved protein (DUF2304)
AHPHCOMF_00486 6.9e-130 arnC M group 2 family protein
AHPHCOMF_00487 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
AHPHCOMF_00488 1e-184 S Glycosyltransferase like family 2
AHPHCOMF_00489 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
AHPHCOMF_00490 2.6e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AHPHCOMF_00491 2e-236 S Predicted membrane protein (DUF2142)
AHPHCOMF_00492 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
AHPHCOMF_00493 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
AHPHCOMF_00494 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AHPHCOMF_00495 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AHPHCOMF_00496 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AHPHCOMF_00497 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
AHPHCOMF_00498 2.1e-202 arcT 2.6.1.1 E Aminotransferase
AHPHCOMF_00499 9.4e-136 ET ABC transporter
AHPHCOMF_00500 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
AHPHCOMF_00501 2.9e-84 mutT 3.6.1.55 F Nudix family
AHPHCOMF_00502 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AHPHCOMF_00504 2e-78 S CAAX amino terminal protease family protein
AHPHCOMF_00505 7.6e-32 S CAAX amino terminal protease family protein
AHPHCOMF_00506 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
AHPHCOMF_00507 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
AHPHCOMF_00508 1.1e-16 XK27_00735
AHPHCOMF_00509 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AHPHCOMF_00511 6.2e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AHPHCOMF_00514 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
AHPHCOMF_00515 6.6e-30 ycaO O OsmC-like protein
AHPHCOMF_00517 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
AHPHCOMF_00519 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
AHPHCOMF_00520 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_00521 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_00522 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AHPHCOMF_00523 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
AHPHCOMF_00524 1.6e-297 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AHPHCOMF_00525 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AHPHCOMF_00526 2.6e-109 3.1.3.18 S IA, variant 1
AHPHCOMF_00527 2.2e-117 lrgB M effector of murein hydrolase
AHPHCOMF_00528 7.7e-56 lrgA S Effector of murein hydrolase LrgA
AHPHCOMF_00530 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
AHPHCOMF_00531 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
AHPHCOMF_00532 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AHPHCOMF_00533 1.3e-104 wecD M Acetyltransferase (GNAT) domain
AHPHCOMF_00534 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AHPHCOMF_00535 5.1e-96 GK ROK family
AHPHCOMF_00536 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
AHPHCOMF_00537 6.6e-62 XK27_08050 O stress-induced mitochondrial fusion
AHPHCOMF_00538 9.6e-26 XK27_08050 O HflC and HflK could regulate a protease
AHPHCOMF_00539 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
AHPHCOMF_00540 2.3e-206 potD P spermidine putrescine ABC transporter
AHPHCOMF_00541 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
AHPHCOMF_00542 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
AHPHCOMF_00543 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AHPHCOMF_00544 2.3e-170 murB 1.3.1.98 M cell wall formation
AHPHCOMF_00545 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AHPHCOMF_00546 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AHPHCOMF_00547 6e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
AHPHCOMF_00548 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AHPHCOMF_00549 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
AHPHCOMF_00550 0.0 ydaO E amino acid
AHPHCOMF_00551 2.1e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AHPHCOMF_00552 4.1e-37 ylqC L Belongs to the UPF0109 family
AHPHCOMF_00553 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AHPHCOMF_00554 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
AHPHCOMF_00555 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
AHPHCOMF_00556 2.1e-74 S QueT transporter
AHPHCOMF_00557 4.9e-120 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
AHPHCOMF_00558 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AHPHCOMF_00559 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AHPHCOMF_00560 3.7e-85 ccl S cog cog4708
AHPHCOMF_00561 2.8e-163 rbn E Belongs to the UPF0761 family
AHPHCOMF_00562 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
AHPHCOMF_00563 3.3e-231 ytoI K transcriptional regulator containing CBS domains
AHPHCOMF_00564 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
AHPHCOMF_00565 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AHPHCOMF_00566 0.0 comEC S Competence protein ComEC
AHPHCOMF_00567 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
AHPHCOMF_00568 1.3e-142 plsC 2.3.1.51 I Acyltransferase
AHPHCOMF_00569 4.4e-73 nodB3 G polysaccharide deacetylase
AHPHCOMF_00570 1.5e-61 nodB3 G deacetylase
AHPHCOMF_00571 7.1e-141 yabB 2.1.1.223 L Methyltransferase
AHPHCOMF_00572 1e-41 yazA L endonuclease containing a URI domain
AHPHCOMF_00573 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AHPHCOMF_00574 3.9e-154 corA P CorA-like protein
AHPHCOMF_00575 1.9e-62 yjqA S Bacterial PH domain
AHPHCOMF_00576 7.8e-100 thiT S Thiamine transporter
AHPHCOMF_00577 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_00578 6e-175 yjbB G Permeases of the major facilitator superfamily
AHPHCOMF_00579 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AHPHCOMF_00580 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
AHPHCOMF_00581 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AHPHCOMF_00585 1.1e-155 cjaA ET ABC transporter substrate-binding protein
AHPHCOMF_00586 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
AHPHCOMF_00587 1.3e-114 P ABC transporter (Permease
AHPHCOMF_00588 1e-114 papP P ABC transporter (Permease
AHPHCOMF_00589 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AHPHCOMF_00590 2e-29 copZ 2.7.7.77 P Heavy metal-associated domain protein
AHPHCOMF_00591 0.0 copA 3.6.3.54 P P-type ATPase
AHPHCOMF_00592 2.7e-73 copY K Copper transport repressor, CopY TcrY family
AHPHCOMF_00593 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AHPHCOMF_00594 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AHPHCOMF_00595 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
AHPHCOMF_00596 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
AHPHCOMF_00597 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AHPHCOMF_00598 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
AHPHCOMF_00599 2.4e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AHPHCOMF_00600 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
AHPHCOMF_00601 3.2e-56
AHPHCOMF_00602 0.0 ctpE P E1-E2 ATPase
AHPHCOMF_00603 3.9e-26
AHPHCOMF_00604 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AHPHCOMF_00605 9.7e-28 L transposase activity
AHPHCOMF_00606 2.7e-129 K transcriptional regulator, MerR family
AHPHCOMF_00607 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
AHPHCOMF_00608 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
AHPHCOMF_00609 4.8e-63 XK27_02560 S cog cog2151
AHPHCOMF_00610 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AHPHCOMF_00611 7.7e-227 ytfP S Flavoprotein
AHPHCOMF_00613 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AHPHCOMF_00614 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
AHPHCOMF_00615 3e-182 ecsB U ABC transporter
AHPHCOMF_00616 2.3e-133 ecsA V abc transporter atp-binding protein
AHPHCOMF_00617 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AHPHCOMF_00618 5.6e-12
AHPHCOMF_00619 8.1e-106
AHPHCOMF_00620 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
AHPHCOMF_00621 6.9e-206 ylbM S Belongs to the UPF0348 family
AHPHCOMF_00622 2e-140 yqeM Q Methyltransferase domain protein
AHPHCOMF_00623 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AHPHCOMF_00624 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
AHPHCOMF_00625 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AHPHCOMF_00626 3.5e-49 yhbY J RNA-binding protein
AHPHCOMF_00627 8.4e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
AHPHCOMF_00628 1.8e-98 yqeG S hydrolase of the HAD superfamily
AHPHCOMF_00629 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AHPHCOMF_00630 1.3e-57
AHPHCOMF_00631 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHPHCOMF_00632 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AHPHCOMF_00633 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHPHCOMF_00634 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
AHPHCOMF_00635 2.9e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AHPHCOMF_00636 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AHPHCOMF_00637 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHPHCOMF_00638 1.1e-153 hlpA M Belongs to the NlpA lipoprotein family
AHPHCOMF_00639 6.8e-101 pncA Q isochorismatase
AHPHCOMF_00640 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AHPHCOMF_00641 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
AHPHCOMF_00642 2.4e-75 XK27_03180 T universal stress protein
AHPHCOMF_00645 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AHPHCOMF_00646 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
AHPHCOMF_00647 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
AHPHCOMF_00648 0.0 yjcE P NhaP-type Na H and K H antiporters
AHPHCOMF_00650 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
AHPHCOMF_00651 1.3e-184 yhcC S radical SAM protein
AHPHCOMF_00652 2.2e-196 ylbL T Belongs to the peptidase S16 family
AHPHCOMF_00653 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AHPHCOMF_00654 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
AHPHCOMF_00655 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AHPHCOMF_00656 1.9e-09 S Protein of unknown function (DUF4059)
AHPHCOMF_00657 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
AHPHCOMF_00658 1e-162 yxeN P ABC transporter (Permease
AHPHCOMF_00659 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AHPHCOMF_00661 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHPHCOMF_00662 0.0 pflB 2.3.1.54 C formate acetyltransferase'
AHPHCOMF_00663 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
AHPHCOMF_00664 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AHPHCOMF_00665 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
AHPHCOMF_00666 2.9e-87 D nuclear chromosome segregation
AHPHCOMF_00667 1.5e-127 ybbM S transport system, permease component
AHPHCOMF_00668 3.6e-117 ybbL S abc transporter atp-binding protein
AHPHCOMF_00669 6.5e-184 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
AHPHCOMF_00670 1.7e-139 cppA E CppA N-terminal
AHPHCOMF_00671 5e-44 V CAAX protease self-immunity
AHPHCOMF_00672 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
AHPHCOMF_00673 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AHPHCOMF_00676 6.8e-47 spiA K sequence-specific DNA binding
AHPHCOMF_00677 2.9e-28 blpT
AHPHCOMF_00678 1.2e-91 blpT
AHPHCOMF_00679 3.9e-122 L Transposase
AHPHCOMF_00680 3.6e-165 L integrase core domain
AHPHCOMF_00685 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
AHPHCOMF_00688 4e-133 agrA KT phosphorelay signal transduction system
AHPHCOMF_00689 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
AHPHCOMF_00691 1.6e-236 mesE M Transport protein ComB
AHPHCOMF_00692 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AHPHCOMF_00693 0.0 mdlB V abc transporter atp-binding protein
AHPHCOMF_00694 0.0 mdlA V abc transporter atp-binding protein
AHPHCOMF_00696 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
AHPHCOMF_00697 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AHPHCOMF_00698 2.3e-72 yutD J protein conserved in bacteria
AHPHCOMF_00699 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AHPHCOMF_00701 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AHPHCOMF_00702 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AHPHCOMF_00703 0.0 ftsI 3.4.16.4 M penicillin-binding protein
AHPHCOMF_00704 8.1e-46 ftsL D cell division protein FtsL
AHPHCOMF_00705 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AHPHCOMF_00706 4.7e-65
AHPHCOMF_00707 2.7e-52
AHPHCOMF_00709 8.7e-33 yhaI J Protein of unknown function (DUF805)
AHPHCOMF_00710 4.5e-18 D nuclear chromosome segregation
AHPHCOMF_00711 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AHPHCOMF_00712 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AHPHCOMF_00713 2.2e-285 XK27_00765
AHPHCOMF_00714 8.1e-134 ecsA_2 V abc transporter atp-binding protein
AHPHCOMF_00715 5.2e-125 S Protein of unknown function (DUF554)
AHPHCOMF_00716 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AHPHCOMF_00717 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AHPHCOMF_00718 2.6e-121 liaI S membrane
AHPHCOMF_00719 5.2e-75 XK27_02470 K LytTr DNA-binding domain
AHPHCOMF_00720 3.6e-66 KT response to antibiotic
AHPHCOMF_00721 1.5e-80 yebC M Membrane
AHPHCOMF_00722 2.9e-18 yebC M Membrane
AHPHCOMF_00723 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
AHPHCOMF_00724 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
AHPHCOMF_00726 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AHPHCOMF_00727 1.7e-183 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AHPHCOMF_00728 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AHPHCOMF_00729 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHPHCOMF_00730 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHPHCOMF_00731 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AHPHCOMF_00733 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
AHPHCOMF_00734 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
AHPHCOMF_00735 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
AHPHCOMF_00736 5.4e-291 scrB 3.2.1.26 GH32 G invertase
AHPHCOMF_00737 7.5e-180 scrR K Transcriptional
AHPHCOMF_00738 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AHPHCOMF_00739 3.4e-62 yqhY S protein conserved in bacteria
AHPHCOMF_00740 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AHPHCOMF_00741 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
AHPHCOMF_00742 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
AHPHCOMF_00744 1.3e-08 V 'abc transporter, ATP-binding protein
AHPHCOMF_00745 1.6e-19 V 'abc transporter, ATP-binding protein
AHPHCOMF_00746 2.4e-60 V 'abc transporter, ATP-binding protein
AHPHCOMF_00749 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AHPHCOMF_00750 2e-169 corA P COG0598 Mg2 and Co2 transporters
AHPHCOMF_00751 2.6e-123 XK27_01040 S Pfam PF06570
AHPHCOMF_00753 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AHPHCOMF_00754 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AHPHCOMF_00755 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
AHPHCOMF_00756 3.6e-41 XK27_05745
AHPHCOMF_00757 2.5e-230 mutY L A G-specific adenine glycosylase
AHPHCOMF_00762 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHPHCOMF_00763 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AHPHCOMF_00764 1e-93 cvpA S toxin biosynthetic process
AHPHCOMF_00765 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AHPHCOMF_00766 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AHPHCOMF_00767 2.6e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AHPHCOMF_00768 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AHPHCOMF_00769 2e-47 azlD E branched-chain amino acid
AHPHCOMF_00770 1.8e-114 azlC E AzlC protein
AHPHCOMF_00771 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AHPHCOMF_00772 3.7e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AHPHCOMF_00773 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
AHPHCOMF_00774 2.5e-33 ykzG S Belongs to the UPF0356 family
AHPHCOMF_00775 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AHPHCOMF_00776 2.7e-40 pscB M CHAP domain protein
AHPHCOMF_00777 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
AHPHCOMF_00778 8.5e-63 glnR K Transcriptional regulator
AHPHCOMF_00779 1.3e-87 S Fusaric acid resistance protein-like
AHPHCOMF_00780 1.1e-12
AHPHCOMF_00781 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AHPHCOMF_00782 3.2e-42 L Transposase
AHPHCOMF_00783 1.9e-46 L transposase activity
AHPHCOMF_00784 7.4e-23 L Transposase
AHPHCOMF_00785 1.8e-56 L transposition
AHPHCOMF_00786 9.1e-83 L Integrase core domain protein
AHPHCOMF_00787 7e-107 L Transposase
AHPHCOMF_00788 1.5e-42 L Transposase
AHPHCOMF_00789 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AHPHCOMF_00790 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AHPHCOMF_00791 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AHPHCOMF_00792 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AHPHCOMF_00793 1.1e-142 purR 2.4.2.7 F operon repressor
AHPHCOMF_00794 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
AHPHCOMF_00795 6.9e-173 rmuC S RmuC domain protein
AHPHCOMF_00796 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
AHPHCOMF_00797 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AHPHCOMF_00798 7.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AHPHCOMF_00800 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AHPHCOMF_00801 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AHPHCOMF_00802 4.1e-144 tatD L Hydrolase, tatd
AHPHCOMF_00803 6.1e-73 yccU S CoA-binding protein
AHPHCOMF_00804 4.8e-51 trxA O Belongs to the thioredoxin family
AHPHCOMF_00805 7.8e-143 S Macro domain protein
AHPHCOMF_00806 3.1e-10 L thioesterase
AHPHCOMF_00807 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
AHPHCOMF_00811 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AHPHCOMF_00812 5e-84 L Transposase
AHPHCOMF_00813 4.7e-249 L Transposase
AHPHCOMF_00814 1e-13 rpmH J Ribosomal protein L34
AHPHCOMF_00815 2e-186 jag S RNA-binding protein
AHPHCOMF_00816 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AHPHCOMF_00817 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AHPHCOMF_00818 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
AHPHCOMF_00819 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AHPHCOMF_00820 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHPHCOMF_00821 7.4e-80 amiA E transmembrane transport
AHPHCOMF_00822 7.3e-69 amiA E transmembrane transport
AHPHCOMF_00823 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AHPHCOMF_00824 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AHPHCOMF_00825 9.2e-51 S Protein of unknown function (DUF3397)
AHPHCOMF_00826 2.3e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
AHPHCOMF_00827 1.1e-57 WQ51_05710 S Mitochondrial biogenesis AIM24
AHPHCOMF_00828 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
AHPHCOMF_00829 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AHPHCOMF_00830 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
AHPHCOMF_00831 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
AHPHCOMF_00832 4.3e-77 XK27_09620 S reductase
AHPHCOMF_00833 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
AHPHCOMF_00834 3.1e-115 XK27_09615 C reductase
AHPHCOMF_00835 1.6e-61 fnt P Formate nitrite transporter
AHPHCOMF_00836 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
AHPHCOMF_00837 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AHPHCOMF_00838 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AHPHCOMF_00839 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
AHPHCOMF_00840 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AHPHCOMF_00841 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AHPHCOMF_00842 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AHPHCOMF_00843 2.7e-48 S glycolate biosynthetic process
AHPHCOMF_00844 3.4e-64 S phosphatase activity
AHPHCOMF_00845 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
AHPHCOMF_00848 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AHPHCOMF_00849 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AHPHCOMF_00850 4.1e-36 yeeD O sulfur carrier activity
AHPHCOMF_00851 1.3e-190 yeeE S Sulphur transport
AHPHCOMF_00852 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AHPHCOMF_00853 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AHPHCOMF_00854 4.1e-09 S Domain of unknown function (DUF4651)
AHPHCOMF_00855 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
AHPHCOMF_00856 1.5e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AHPHCOMF_00857 1.8e-111 S CAAX amino terminal protease family protein
AHPHCOMF_00859 5e-67 V CAAX protease self-immunity
AHPHCOMF_00860 1.4e-33 V CAAX protease self-immunity
AHPHCOMF_00862 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AHPHCOMF_00863 5.9e-177 ytxK 2.1.1.72 L DNA methylase
AHPHCOMF_00864 2e-12 comGF U Putative Competence protein ComGF
AHPHCOMF_00865 1.5e-71 comGF U Competence protein ComGF
AHPHCOMF_00866 1.4e-15 NU Type II secretory pathway pseudopilin
AHPHCOMF_00867 1.8e-57 cglD NU Competence protein
AHPHCOMF_00868 8.5e-43 comGC U Required for transformation and DNA binding
AHPHCOMF_00869 3e-145 cglB NU type II secretion system
AHPHCOMF_00870 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AHPHCOMF_00871 2.9e-68 S cog cog4699
AHPHCOMF_00872 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHPHCOMF_00873 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHPHCOMF_00874 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AHPHCOMF_00875 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AHPHCOMF_00876 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AHPHCOMF_00877 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
AHPHCOMF_00878 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
AHPHCOMF_00879 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AHPHCOMF_00880 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AHPHCOMF_00881 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
AHPHCOMF_00882 1.4e-57 asp S cog cog1302
AHPHCOMF_00883 9.3e-226 norN V Mate efflux family protein
AHPHCOMF_00884 2.4e-278 thrC 4.2.3.1 E Threonine synthase
AHPHCOMF_00885 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AHPHCOMF_00886 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
AHPHCOMF_00887 3.3e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AHPHCOMF_00888 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AHPHCOMF_00889 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
AHPHCOMF_00890 0.0 pepO 3.4.24.71 O Peptidase family M13
AHPHCOMF_00891 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AHPHCOMF_00892 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AHPHCOMF_00893 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AHPHCOMF_00894 1.4e-54 treB 2.7.1.201 G PTS System
AHPHCOMF_00895 5.8e-21 treR K DNA-binding transcription factor activity
AHPHCOMF_00896 1.2e-85 treR K trehalose operon
AHPHCOMF_00897 3.3e-95 ywlG S Belongs to the UPF0340 family
AHPHCOMF_00900 2e-35 L PFAM Integrase, catalytic core
AHPHCOMF_00901 8e-96 L PFAM Integrase, catalytic core
AHPHCOMF_00902 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
AHPHCOMF_00904 8.8e-110 6.3.2.2 H ergothioneine biosynthetic process
AHPHCOMF_00905 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
AHPHCOMF_00906 2.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
AHPHCOMF_00907 3.3e-09 L PFAM Integrase, catalytic core
AHPHCOMF_00908 1.8e-111 L PFAM Integrase, catalytic core
AHPHCOMF_00909 7.4e-62 rplQ J ribosomal protein l17
AHPHCOMF_00910 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AHPHCOMF_00911 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AHPHCOMF_00912 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AHPHCOMF_00913 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AHPHCOMF_00914 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AHPHCOMF_00915 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AHPHCOMF_00916 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AHPHCOMF_00917 4.4e-58 rplO J binds to the 23S rRNA
AHPHCOMF_00918 2.5e-23 rpmD J ribosomal protein l30
AHPHCOMF_00919 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AHPHCOMF_00920 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AHPHCOMF_00921 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AHPHCOMF_00922 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AHPHCOMF_00923 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AHPHCOMF_00924 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AHPHCOMF_00925 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AHPHCOMF_00926 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AHPHCOMF_00927 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AHPHCOMF_00928 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
AHPHCOMF_00929 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AHPHCOMF_00930 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AHPHCOMF_00931 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AHPHCOMF_00932 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AHPHCOMF_00933 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AHPHCOMF_00934 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AHPHCOMF_00935 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
AHPHCOMF_00936 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AHPHCOMF_00937 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
AHPHCOMF_00938 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AHPHCOMF_00939 0.0 XK27_09800 I Acyltransferase
AHPHCOMF_00940 1.7e-35 XK27_09805 S MORN repeat protein
AHPHCOMF_00941 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AHPHCOMF_00942 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AHPHCOMF_00943 1.5e-89 adk 2.7.4.3 F topology modulation protein
AHPHCOMF_00944 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_00945 1.4e-127 Z012_04635 K sequence-specific DNA binding
AHPHCOMF_00947 6.3e-16 C Radical SAM
AHPHCOMF_00948 3.4e-191 C Radical SAM
AHPHCOMF_00949 3.9e-287 V ABC transporter transmembrane region
AHPHCOMF_00950 2.5e-89 K sequence-specific DNA binding
AHPHCOMF_00951 1.3e-36 L Replication initiation factor
AHPHCOMF_00952 1.6e-106 L Replication initiation factor
AHPHCOMF_00953 1.9e-18 S Domain of unknown function (DUF3173)
AHPHCOMF_00954 1.3e-215 int L Belongs to the 'phage' integrase family
AHPHCOMF_00956 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
AHPHCOMF_00957 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AHPHCOMF_00958 2.8e-44 yrzL S Belongs to the UPF0297 family
AHPHCOMF_00959 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AHPHCOMF_00960 4.2e-44 yrzB S Belongs to the UPF0473 family
AHPHCOMF_00961 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
AHPHCOMF_00962 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AHPHCOMF_00963 7.5e-14
AHPHCOMF_00964 2.6e-91 XK27_10930 K acetyltransferase
AHPHCOMF_00965 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AHPHCOMF_00966 7e-147 yaaA S Belongs to the UPF0246 family
AHPHCOMF_00967 9.9e-169 XK27_01785 S cog cog1284
AHPHCOMF_00968 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AHPHCOMF_00970 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
AHPHCOMF_00971 5.7e-52 metE 2.1.1.14 E Methionine synthase
AHPHCOMF_00972 7.6e-64 metE 2.1.1.14 E Methionine synthase
AHPHCOMF_00973 9.2e-36 metE 2.1.1.14 E Methionine synthase
AHPHCOMF_00974 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AHPHCOMF_00975 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AHPHCOMF_00977 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
AHPHCOMF_00978 2.7e-95 S Hydrophobic domain protein
AHPHCOMF_00980 3.7e-27 S Membrane
AHPHCOMF_00981 3.1e-101
AHPHCOMF_00982 1.8e-23 S Small integral membrane protein
AHPHCOMF_00983 1.2e-71 M Protein conserved in bacteria
AHPHCOMF_00984 4.9e-12 K CsbD-like
AHPHCOMF_00985 1e-33 L Transposase
AHPHCOMF_00986 7.6e-22
AHPHCOMF_00987 1.3e-84 K Peptidase S24-like
AHPHCOMF_00988 2.1e-08 K Peptidase S24-like protein
AHPHCOMF_00989 2.3e-55 E IrrE N-terminal-like domain
AHPHCOMF_00990 8e-49 E IrrE N-terminal-like domain
AHPHCOMF_00991 2e-103 L Transposase
AHPHCOMF_00992 6.6e-37 L Transposase
AHPHCOMF_00993 2.4e-53 L Transposase
AHPHCOMF_00994 2.3e-38 L transposase activity
AHPHCOMF_00995 8.1e-154 L COG2801 Transposase and inactivated derivatives
AHPHCOMF_00996 1e-45 M Glycosyltransferase family 92
AHPHCOMF_00997 4.3e-61 L COG2801 Transposase and inactivated derivatives
AHPHCOMF_00998 4.8e-106 S Putative adhesin
AHPHCOMF_00999 3.9e-161 XK27_06930 V domain protein
AHPHCOMF_01000 1.6e-94 XK27_06935 K transcriptional regulator
AHPHCOMF_01001 4.8e-55 ypaA M Membrane
AHPHCOMF_01002 2.7e-08
AHPHCOMF_01003 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AHPHCOMF_01004 8.2e-48 veg S Biofilm formation stimulator VEG
AHPHCOMF_01005 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AHPHCOMF_01006 3.9e-70 rplI J binds to the 23S rRNA
AHPHCOMF_01007 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AHPHCOMF_01008 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AHPHCOMF_01009 1.5e-77 F NUDIX domain
AHPHCOMF_01010 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AHPHCOMF_01011 0.0 S Bacterial membrane protein, YfhO
AHPHCOMF_01012 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
AHPHCOMF_01013 5.3e-85 lytE M LysM domain protein
AHPHCOMF_01014 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AHPHCOMF_01015 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AHPHCOMF_01016 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AHPHCOMF_01017 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AHPHCOMF_01018 6.3e-138 ymfM S sequence-specific DNA binding
AHPHCOMF_01019 3.1e-242 ymfH S Peptidase M16
AHPHCOMF_01020 1.1e-234 ymfF S Peptidase M16
AHPHCOMF_01021 2.3e-44 yaaA S S4 domain protein YaaA
AHPHCOMF_01022 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AHPHCOMF_01023 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AHPHCOMF_01024 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
AHPHCOMF_01025 5.4e-153 yvjA S membrane
AHPHCOMF_01026 6.7e-306 ybiT S abc transporter atp-binding protein
AHPHCOMF_01027 0.0 XK27_10405 S Bacterial membrane protein YfhO
AHPHCOMF_01031 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
AHPHCOMF_01032 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AHPHCOMF_01033 5.3e-194 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
AHPHCOMF_01034 8.5e-134 parB K Belongs to the ParB family
AHPHCOMF_01035 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AHPHCOMF_01036 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AHPHCOMF_01037 1.1e-29 yyzM S Protein conserved in bacteria
AHPHCOMF_01038 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AHPHCOMF_01039 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AHPHCOMF_01040 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AHPHCOMF_01041 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
AHPHCOMF_01042 3.5e-61 divIC D Septum formation initiator
AHPHCOMF_01044 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
AHPHCOMF_01045 7.2e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AHPHCOMF_01046 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AHPHCOMF_01047 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHPHCOMF_01048 1.7e-162 L Transposase
AHPHCOMF_01049 3.2e-46 L Transposase
AHPHCOMF_01050 2.5e-23 L Transposase
AHPHCOMF_01051 4.2e-29 L transposition
AHPHCOMF_01064 5.3e-11
AHPHCOMF_01070 5.5e-139 mreC M Involved in formation and maintenance of cell shape
AHPHCOMF_01071 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AHPHCOMF_01072 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
AHPHCOMF_01073 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AHPHCOMF_01074 2.9e-218 araT 2.6.1.1 E Aminotransferase
AHPHCOMF_01075 7e-144 recO L Involved in DNA repair and RecF pathway recombination
AHPHCOMF_01076 1.1e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AHPHCOMF_01077 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AHPHCOMF_01078 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AHPHCOMF_01079 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AHPHCOMF_01080 3.8e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AHPHCOMF_01081 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AHPHCOMF_01082 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AHPHCOMF_01083 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AHPHCOMF_01084 1e-90 L transposase activity
AHPHCOMF_01085 3.5e-50 L transposition
AHPHCOMF_01086 2e-32 L Integrase core domain protein
AHPHCOMF_01087 2.3e-161 S CHAP domain
AHPHCOMF_01088 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
AHPHCOMF_01089 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AHPHCOMF_01090 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AHPHCOMF_01091 9.2e-141 1.1.1.169 H Ketopantoate reductase
AHPHCOMF_01092 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AHPHCOMF_01093 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AHPHCOMF_01094 8.2e-70 argR K Regulates arginine biosynthesis genes
AHPHCOMF_01095 1.5e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
AHPHCOMF_01096 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AHPHCOMF_01097 7e-34 S Protein of unknown function (DUF3021)
AHPHCOMF_01098 1.2e-61 KT phosphorelay signal transduction system
AHPHCOMF_01100 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AHPHCOMF_01102 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AHPHCOMF_01103 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
AHPHCOMF_01104 3.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
AHPHCOMF_01105 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AHPHCOMF_01106 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
AHPHCOMF_01112 2.6e-10
AHPHCOMF_01115 1.9e-07
AHPHCOMF_01120 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AHPHCOMF_01121 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
AHPHCOMF_01122 5.5e-36 XK27_02060 S Transglycosylase associated protein
AHPHCOMF_01123 2.6e-55 badR K DNA-binding transcription factor activity
AHPHCOMF_01124 3.5e-97 S reductase
AHPHCOMF_01125 1e-87 L Integrase core domain protein
AHPHCOMF_01126 2.3e-38 L transposition
AHPHCOMF_01127 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
AHPHCOMF_01128 1.9e-86 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
AHPHCOMF_01131 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
AHPHCOMF_01132 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AHPHCOMF_01133 1.1e-83 S Putative small multi-drug export protein
AHPHCOMF_01134 6.2e-76 ctsR K Belongs to the CtsR family
AHPHCOMF_01135 0.0 clpC O Belongs to the ClpA ClpB family
AHPHCOMF_01136 3.5e-150 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AHPHCOMF_01137 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AHPHCOMF_01138 1.2e-165 L integrase core domain
AHPHCOMF_01139 4.3e-121 L Helix-turn-helix domain
AHPHCOMF_01140 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AHPHCOMF_01141 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AHPHCOMF_01142 1.3e-105 S SseB protein N-terminal domain
AHPHCOMF_01143 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
AHPHCOMF_01144 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AHPHCOMF_01145 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AHPHCOMF_01148 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHPHCOMF_01149 3.5e-91 yacP S RNA-binding protein containing a PIN domain
AHPHCOMF_01150 1.7e-154 degV S DegV family
AHPHCOMF_01152 4.7e-32 K helix-turn-helix
AHPHCOMF_01153 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AHPHCOMF_01154 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AHPHCOMF_01155 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
AHPHCOMF_01156 9.3e-184 L Phage integrase family
AHPHCOMF_01157 1.7e-22
AHPHCOMF_01158 1.3e-154
AHPHCOMF_01160 1.3e-134 D ftsk spoiiie
AHPHCOMF_01161 5.3e-18 D FtsK/SpoIIIE family
AHPHCOMF_01164 3.7e-226 sthIM 2.1.1.72 L DNA methylase
AHPHCOMF_01165 0.0 res_1 3.1.21.5 S Type III restriction
AHPHCOMF_01167 8.5e-112 int L Belongs to the 'phage' integrase family
AHPHCOMF_01168 3.4e-83 int L Belongs to the 'phage' integrase family
AHPHCOMF_01169 2.2e-35 S Helix-turn-helix domain
AHPHCOMF_01171 2.4e-117
AHPHCOMF_01173 6.9e-53 isp2 S pathogenesis
AHPHCOMF_01174 2.9e-125 tnp L Transposase IS66 family
AHPHCOMF_01175 3.7e-224 capA M Bacterial capsule synthesis protein
AHPHCOMF_01176 3.6e-39 gcvR T UPF0237 protein
AHPHCOMF_01177 1.9e-242 XK27_08635 S UPF0210 protein
AHPHCOMF_01178 2.2e-38 ais G alpha-ribazole phosphatase activity
AHPHCOMF_01179 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
AHPHCOMF_01180 1.3e-102 acmA 3.2.1.17 NU amidase activity
AHPHCOMF_01181 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AHPHCOMF_01182 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AHPHCOMF_01183 9.8e-298 dnaK O Heat shock 70 kDa protein
AHPHCOMF_01184 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AHPHCOMF_01185 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AHPHCOMF_01186 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
AHPHCOMF_01187 1.7e-60 hmpT S membrane
AHPHCOMF_01200 2.5e-169 L Transposase
AHPHCOMF_01201 9.9e-19 S Domain of unknown function (DUF4649)
AHPHCOMF_01202 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AHPHCOMF_01203 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AHPHCOMF_01204 6.5e-87
AHPHCOMF_01205 1.6e-77 sigH K DNA-templated transcription, initiation
AHPHCOMF_01206 6.6e-148 ykuT M mechanosensitive ion channel
AHPHCOMF_01207 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AHPHCOMF_01208 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AHPHCOMF_01209 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AHPHCOMF_01210 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
AHPHCOMF_01211 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
AHPHCOMF_01212 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
AHPHCOMF_01213 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AHPHCOMF_01214 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AHPHCOMF_01215 2.4e-83 nrdI F Belongs to the NrdI family
AHPHCOMF_01216 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AHPHCOMF_01217 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AHPHCOMF_01218 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AHPHCOMF_01219 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AHPHCOMF_01220 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AHPHCOMF_01221 1.9e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AHPHCOMF_01222 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AHPHCOMF_01223 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AHPHCOMF_01224 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AHPHCOMF_01225 6.5e-202 yhjX P Major Facilitator
AHPHCOMF_01226 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AHPHCOMF_01227 5e-94 V VanZ like family
AHPHCOMF_01229 1e-123 glnQ E abc transporter atp-binding protein
AHPHCOMF_01230 1.8e-276 glnP P ABC transporter
AHPHCOMF_01231 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AHPHCOMF_01232 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AHPHCOMF_01233 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
AHPHCOMF_01234 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
AHPHCOMF_01235 6.3e-235 sufD O assembly protein SufD
AHPHCOMF_01236 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AHPHCOMF_01237 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
AHPHCOMF_01238 3.5e-274 sufB O assembly protein SufB
AHPHCOMF_01239 7e-10 oppA E ABC transporter substrate-binding protein
AHPHCOMF_01240 2e-138 oppA E ABC transporter substrate-binding protein
AHPHCOMF_01241 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHPHCOMF_01242 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHPHCOMF_01243 7.3e-74 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHPHCOMF_01244 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AHPHCOMF_01245 3e-27 oppD P Belongs to the ABC transporter superfamily
AHPHCOMF_01246 2.5e-32 oppD P Belongs to the ABC transporter superfamily
AHPHCOMF_01247 1.7e-61 oppD P Belongs to the ABC transporter superfamily
AHPHCOMF_01248 3.1e-43 oppD P Belongs to the ABC transporter superfamily
AHPHCOMF_01249 9e-170 oppF P Belongs to the ABC transporter superfamily
AHPHCOMF_01252 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AHPHCOMF_01253 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AHPHCOMF_01254 1.9e-223 EGP Major facilitator Superfamily
AHPHCOMF_01255 3.1e-72 adcR K transcriptional
AHPHCOMF_01256 6.4e-136 adcC P ABC transporter, ATP-binding protein
AHPHCOMF_01257 2.5e-128 adcB P ABC transporter (Permease
AHPHCOMF_01258 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
AHPHCOMF_01259 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
AHPHCOMF_01260 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
AHPHCOMF_01261 1.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AHPHCOMF_01262 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
AHPHCOMF_01263 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
AHPHCOMF_01264 1.9e-127 yeeN K transcriptional regulatory protein
AHPHCOMF_01265 9.8e-50 yajC U protein transport
AHPHCOMF_01266 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AHPHCOMF_01267 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
AHPHCOMF_01268 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AHPHCOMF_01269 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AHPHCOMF_01270 0.0 WQ51_06230 S ABC transporter substrate binding protein
AHPHCOMF_01271 5.2e-142 cmpC S abc transporter atp-binding protein
AHPHCOMF_01272 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AHPHCOMF_01273 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AHPHCOMF_01274 4.4e-37 L Transposase
AHPHCOMF_01275 1.9e-17 L transposase activity
AHPHCOMF_01278 4.7e-43
AHPHCOMF_01279 9.9e-55 S TM2 domain
AHPHCOMF_01280 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AHPHCOMF_01281 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AHPHCOMF_01282 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AHPHCOMF_01283 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
AHPHCOMF_01284 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
AHPHCOMF_01285 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
AHPHCOMF_01286 6e-55 cof Q phosphatase activity
AHPHCOMF_01287 1.1e-34 cof Q phosphatase activity
AHPHCOMF_01288 3.1e-136 glcR K transcriptional regulator (DeoR family)
AHPHCOMF_01289 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AHPHCOMF_01290 3.8e-40 K transcriptional
AHPHCOMF_01292 2.6e-76 S thiolester hydrolase activity
AHPHCOMF_01293 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
AHPHCOMF_01294 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AHPHCOMF_01295 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AHPHCOMF_01296 1.9e-77 yhaI L Membrane
AHPHCOMF_01297 4.6e-260 pepC 3.4.22.40 E aminopeptidase
AHPHCOMF_01298 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AHPHCOMF_01299 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AHPHCOMF_01300 3.1e-95 ypsA S Belongs to the UPF0398 family
AHPHCOMF_01301 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AHPHCOMF_01302 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AHPHCOMF_01303 1.1e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
AHPHCOMF_01304 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
AHPHCOMF_01305 2.5e-23
AHPHCOMF_01306 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AHPHCOMF_01307 7.3e-80 XK27_09675 K -acetyltransferase
AHPHCOMF_01308 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AHPHCOMF_01309 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AHPHCOMF_01310 5.2e-59 L Integrase core domain protein
AHPHCOMF_01311 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AHPHCOMF_01312 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AHPHCOMF_01313 2.5e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHPHCOMF_01314 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
AHPHCOMF_01315 8.8e-98 ybhL S Belongs to the BI1 family
AHPHCOMF_01318 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AHPHCOMF_01319 3.7e-91 K transcriptional regulator
AHPHCOMF_01320 7.6e-36 yneF S UPF0154 protein
AHPHCOMF_01321 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AHPHCOMF_01322 1.3e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AHPHCOMF_01323 3.5e-99 XK27_09740 S Phosphoesterase
AHPHCOMF_01324 7.8e-85 ykuL S CBS domain
AHPHCOMF_01325 1.1e-136 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
AHPHCOMF_01326 9e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AHPHCOMF_01327 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AHPHCOMF_01328 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AHPHCOMF_01329 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AHPHCOMF_01330 1.2e-258 trkH P Cation transport protein
AHPHCOMF_01331 1.3e-246 trkA P Potassium transporter peripheral membrane component
AHPHCOMF_01332 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AHPHCOMF_01333 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AHPHCOMF_01334 7e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
AHPHCOMF_01335 1.6e-160 K sequence-specific DNA binding
AHPHCOMF_01336 1.9e-33 V protein secretion by the type I secretion system
AHPHCOMF_01337 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AHPHCOMF_01338 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AHPHCOMF_01339 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AHPHCOMF_01340 3.7e-51 yhaI L Membrane
AHPHCOMF_01341 6.7e-36 S Domain of unknown function (DUF4173)
AHPHCOMF_01342 9.2e-132 S Domain of unknown function (DUF4173)
AHPHCOMF_01343 6.8e-95 ureI S AmiS/UreI family transporter
AHPHCOMF_01344 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
AHPHCOMF_01345 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
AHPHCOMF_01346 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AHPHCOMF_01347 6.6e-78 ureE O enzyme active site formation
AHPHCOMF_01348 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AHPHCOMF_01349 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AHPHCOMF_01350 4.9e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AHPHCOMF_01351 2.7e-177 cbiM P PDGLE domain
AHPHCOMF_01352 1.1e-136 P cobalt transport protein
AHPHCOMF_01353 1.6e-131 cbiO P ABC transporter
AHPHCOMF_01354 4.5e-152 ET amino acid transport
AHPHCOMF_01355 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
AHPHCOMF_01356 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
AHPHCOMF_01357 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
AHPHCOMF_01358 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
AHPHCOMF_01359 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AHPHCOMF_01360 5.2e-98 metI P ABC transporter (Permease
AHPHCOMF_01361 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AHPHCOMF_01362 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
AHPHCOMF_01363 8e-94 S UPF0397 protein
AHPHCOMF_01364 0.0 ykoD P abc transporter atp-binding protein
AHPHCOMF_01365 1.2e-149 cbiQ P cobalt transport
AHPHCOMF_01366 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AHPHCOMF_01367 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
AHPHCOMF_01368 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
AHPHCOMF_01369 3.4e-242 P COG0168 Trk-type K transport systems, membrane components
AHPHCOMF_01370 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
AHPHCOMF_01371 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
AHPHCOMF_01372 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_01373 2.8e-282 T PhoQ Sensor
AHPHCOMF_01374 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AHPHCOMF_01375 6.5e-218 dnaB L Replication initiation and membrane attachment
AHPHCOMF_01376 5.2e-167 dnaI L Primosomal protein DnaI
AHPHCOMF_01377 4.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AHPHCOMF_01378 1.2e-34
AHPHCOMF_01379 3e-27 L Integrase core domain protein
AHPHCOMF_01380 3.4e-50 L transposition
AHPHCOMF_01381 5.7e-23 L Transposase
AHPHCOMF_01382 7.8e-28 L transposase activity
AHPHCOMF_01383 1.1e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AHPHCOMF_01384 6.5e-63 manO S protein conserved in bacteria
AHPHCOMF_01385 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
AHPHCOMF_01386 1.7e-116 manM G pts system
AHPHCOMF_01387 1.1e-181 manL 2.7.1.191 G pts system
AHPHCOMF_01388 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
AHPHCOMF_01389 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
AHPHCOMF_01390 1.9e-248 pbuO S permease
AHPHCOMF_01391 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
AHPHCOMF_01392 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
AHPHCOMF_01393 2.5e-220 brpA K Transcriptional
AHPHCOMF_01394 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
AHPHCOMF_01395 3.1e-212 nusA K Participates in both transcription termination and antitermination
AHPHCOMF_01396 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
AHPHCOMF_01397 1.4e-41 ylxQ J ribosomal protein
AHPHCOMF_01398 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AHPHCOMF_01399 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AHPHCOMF_01400 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
AHPHCOMF_01401 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
AHPHCOMF_01403 2.1e-213 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
AHPHCOMF_01404 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AHPHCOMF_01405 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
AHPHCOMF_01406 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
AHPHCOMF_01407 1e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
AHPHCOMF_01408 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AHPHCOMF_01410 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AHPHCOMF_01411 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AHPHCOMF_01412 3.4e-74 ylbF S Belongs to the UPF0342 family
AHPHCOMF_01413 7.1e-46 ylbG S UPF0298 protein
AHPHCOMF_01414 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
AHPHCOMF_01415 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_01416 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_01417 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
AHPHCOMF_01418 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
AHPHCOMF_01419 2.8e-70 acuB S IMP dehydrogenase activity
AHPHCOMF_01420 3.3e-43 acuB S IMP dehydrogenase activity
AHPHCOMF_01421 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AHPHCOMF_01422 6.3e-111 yvyE 3.4.13.9 S YigZ family
AHPHCOMF_01423 1.8e-253 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AHPHCOMF_01424 4.4e-123 comFC S Competence protein
AHPHCOMF_01425 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AHPHCOMF_01433 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
AHPHCOMF_01434 6.4e-108 S Domain of unknown function (DUF1803)
AHPHCOMF_01435 7.8e-102 ygaC J Belongs to the UPF0374 family
AHPHCOMF_01436 2.8e-132 recX 2.4.1.337 GT4 S Regulatory protein RecX
AHPHCOMF_01437 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHPHCOMF_01438 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
AHPHCOMF_01439 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
AHPHCOMF_01440 1.9e-115 S Haloacid dehalogenase-like hydrolase
AHPHCOMF_01441 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
AHPHCOMF_01442 5.8e-71 marR K Transcriptional regulator, MarR family
AHPHCOMF_01443 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AHPHCOMF_01444 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AHPHCOMF_01445 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
AHPHCOMF_01446 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AHPHCOMF_01447 1.6e-126 IQ reductase
AHPHCOMF_01448 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AHPHCOMF_01449 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AHPHCOMF_01450 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AHPHCOMF_01451 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
AHPHCOMF_01452 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AHPHCOMF_01453 2e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AHPHCOMF_01454 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AHPHCOMF_01455 5.2e-65 tnp L Transposase
AHPHCOMF_01456 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
AHPHCOMF_01457 6.8e-84 L Transposase
AHPHCOMF_01458 5.6e-114 fruR K transcriptional
AHPHCOMF_01459 2.1e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AHPHCOMF_01460 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
AHPHCOMF_01461 2.2e-49 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
AHPHCOMF_01462 2.7e-126 fruA 2.7.1.202 G phosphotransferase system
AHPHCOMF_01463 1.2e-34 fruA 2.7.1.202 G phosphotransferase system
AHPHCOMF_01464 2.1e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHPHCOMF_01465 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AHPHCOMF_01467 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
AHPHCOMF_01468 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHPHCOMF_01469 3.2e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AHPHCOMF_01470 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AHPHCOMF_01471 6.4e-29 2.3.1.128 K acetyltransferase
AHPHCOMF_01472 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
AHPHCOMF_01473 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AHPHCOMF_01474 2e-126 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AHPHCOMF_01475 2.6e-64 WQ51_03320 S cog cog4835
AHPHCOMF_01476 6.4e-61 XK27_08360 S EDD domain protein, DegV family
AHPHCOMF_01477 2.1e-74 XK27_08360 S EDD domain protein, DegV family
AHPHCOMF_01478 4.3e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AHPHCOMF_01479 9e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AHPHCOMF_01480 0.0 yfmR S abc transporter atp-binding protein
AHPHCOMF_01481 3.3e-25 U response to pH
AHPHCOMF_01482 1e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
AHPHCOMF_01483 3.8e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
AHPHCOMF_01484 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
AHPHCOMF_01485 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AHPHCOMF_01486 1.9e-77 K DNA-binding transcription factor activity
AHPHCOMF_01487 0.0 lmrA1 V abc transporter atp-binding protein
AHPHCOMF_01488 0.0 lmrA2 V abc transporter atp-binding protein
AHPHCOMF_01489 5.4e-45 K Acetyltransferase (GNAT) family
AHPHCOMF_01490 3.2e-78 sptS 2.7.13.3 T Histidine kinase
AHPHCOMF_01491 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AHPHCOMF_01492 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AHPHCOMF_01493 5.3e-161 cvfB S Protein conserved in bacteria
AHPHCOMF_01494 7.4e-35 yozE S Belongs to the UPF0346 family
AHPHCOMF_01495 2.2e-130 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
AHPHCOMF_01496 2.3e-61 rlpA M LysM domain protein
AHPHCOMF_01497 8e-191 phoH T phosphate starvation-inducible protein PhoH
AHPHCOMF_01501 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHPHCOMF_01502 9.2e-164 K transcriptional regulator (lysR family)
AHPHCOMF_01503 1.4e-186 coiA 3.6.4.12 S Competence protein
AHPHCOMF_01504 0.0 pepF E oligoendopeptidase F
AHPHCOMF_01505 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
AHPHCOMF_01506 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
AHPHCOMF_01507 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AHPHCOMF_01508 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
AHPHCOMF_01509 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
AHPHCOMF_01510 5.6e-119 3.4.17.14, 3.5.1.28 NU amidase activity
AHPHCOMF_01511 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AHPHCOMF_01512 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
AHPHCOMF_01513 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AHPHCOMF_01514 8.6e-210 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AHPHCOMF_01515 2.1e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
AHPHCOMF_01516 9e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
AHPHCOMF_01517 3.7e-140 yxkH G deacetylase
AHPHCOMF_01518 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AHPHCOMF_01519 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AHPHCOMF_01520 5.5e-153 rarD S Transporter
AHPHCOMF_01521 2.2e-15 T peptidase
AHPHCOMF_01522 8.9e-14 coiA 3.6.4.12 S Competence protein
AHPHCOMF_01523 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AHPHCOMF_01524 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AHPHCOMF_01525 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AHPHCOMF_01526 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AHPHCOMF_01527 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
AHPHCOMF_01528 3.3e-78 atpF C ATP synthase F(0) sector subunit b
AHPHCOMF_01529 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AHPHCOMF_01530 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AHPHCOMF_01531 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AHPHCOMF_01532 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AHPHCOMF_01533 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AHPHCOMF_01534 2.8e-230 ftsW D Belongs to the SEDS family
AHPHCOMF_01535 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AHPHCOMF_01536 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AHPHCOMF_01537 1.1e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AHPHCOMF_01538 6.4e-162 holB 2.7.7.7 L dna polymerase iii
AHPHCOMF_01539 1.2e-135 yaaT S stage 0 sporulation protein
AHPHCOMF_01540 9.5e-55 yabA L Involved in initiation control of chromosome replication
AHPHCOMF_01541 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AHPHCOMF_01542 5.2e-226 amt P Ammonium Transporter
AHPHCOMF_01543 1.1e-53 glnB K Belongs to the P(II) protein family
AHPHCOMF_01544 4.9e-106 mur1 NU mannosyl-glycoprotein
AHPHCOMF_01545 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
AHPHCOMF_01546 2.1e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
AHPHCOMF_01547 3.6e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AHPHCOMF_01548 1.8e-53
AHPHCOMF_01549 7.5e-26
AHPHCOMF_01550 1.5e-59
AHPHCOMF_01551 6.1e-63 S membrane
AHPHCOMF_01552 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AHPHCOMF_01553 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AHPHCOMF_01554 4.5e-39 ynzC S UPF0291 protein
AHPHCOMF_01555 1.8e-254 cycA E permease
AHPHCOMF_01556 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
AHPHCOMF_01557 1.5e-25 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AHPHCOMF_01558 1.4e-47 pts33BCA G pts system
AHPHCOMF_01559 4.2e-119 pts33BCA G pts system
AHPHCOMF_01560 3.3e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
AHPHCOMF_01561 1.6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHPHCOMF_01566 1.8e-167 fhuR K transcriptional regulator (lysR family)
AHPHCOMF_01567 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AHPHCOMF_01568 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AHPHCOMF_01569 4e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AHPHCOMF_01570 4.9e-227 pyrP F uracil Permease
AHPHCOMF_01571 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AHPHCOMF_01572 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
AHPHCOMF_01573 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
AHPHCOMF_01574 6.4e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
AHPHCOMF_01575 4.4e-30 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHPHCOMF_01576 3.6e-35 V efflux transmembrane transporter activity
AHPHCOMF_01577 3.1e-31 V efflux transmembrane transporter activity
AHPHCOMF_01578 1.2e-26 ytrF V efflux transmembrane transporter activity
AHPHCOMF_01579 1.6e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AHPHCOMF_01580 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AHPHCOMF_01581 8e-216 L Transposase
AHPHCOMF_01582 1.6e-18 L Integrase core domain
AHPHCOMF_01583 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
AHPHCOMF_01584 2.8e-164 hrtB V MacB-like periplasmic core domain
AHPHCOMF_01587 3e-92 S MucBP domain
AHPHCOMF_01588 1.9e-49 M YSIRK type signal peptide
AHPHCOMF_01589 0.0 M the current gene model (or a revised gene model) may contain a
AHPHCOMF_01591 0.0 mdlB V abc transporter atp-binding protein
AHPHCOMF_01592 0.0 lmrA V abc transporter atp-binding protein
AHPHCOMF_01593 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AHPHCOMF_01594 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AHPHCOMF_01595 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
AHPHCOMF_01596 2.1e-131 rr02 KT response regulator
AHPHCOMF_01597 1.1e-217 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AHPHCOMF_01598 4.8e-168 V ABC transporter
AHPHCOMF_01599 5.4e-122 sagI S ABC-2 type transporter
AHPHCOMF_01600 1e-195 yceA S Belongs to the UPF0176 family
AHPHCOMF_01601 3.3e-22
AHPHCOMF_01602 1.5e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
AHPHCOMF_01603 5.6e-113 S VIT family
AHPHCOMF_01604 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AHPHCOMF_01605 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AHPHCOMF_01606 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
AHPHCOMF_01607 2.2e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
AHPHCOMF_01608 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHPHCOMF_01609 1.4e-104 GBS0088 J protein conserved in bacteria
AHPHCOMF_01610 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AHPHCOMF_01611 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AHPHCOMF_01612 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
AHPHCOMF_01613 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AHPHCOMF_01614 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AHPHCOMF_01615 8.5e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
AHPHCOMF_01616 2.5e-21
AHPHCOMF_01617 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AHPHCOMF_01619 3.5e-07 U protein secretion
AHPHCOMF_01620 2.7e-50 U protein secretion
AHPHCOMF_01621 1.1e-11 U protein secretion
AHPHCOMF_01622 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
AHPHCOMF_01623 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
AHPHCOMF_01624 4.9e-21 XK27_13030
AHPHCOMF_01625 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AHPHCOMF_01626 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AHPHCOMF_01627 9.8e-163 S Protein of unknown function (DUF3114)
AHPHCOMF_01628 1.2e-22 S Protein of unknown function (DUF3114)
AHPHCOMF_01629 1.1e-116 yqfA K protein, Hemolysin III
AHPHCOMF_01630 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AHPHCOMF_01631 1.7e-218 mvaS 2.3.3.10 I synthase
AHPHCOMF_01632 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AHPHCOMF_01633 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AHPHCOMF_01634 9.7e-22
AHPHCOMF_01635 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AHPHCOMF_01636 4.3e-109 engB D Necessary for normal cell division and for the maintenance of normal septation
AHPHCOMF_01637 4.1e-248 mmuP E amino acid
AHPHCOMF_01638 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
AHPHCOMF_01639 1.4e-29 S Domain of unknown function (DUF1912)
AHPHCOMF_01640 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
AHPHCOMF_01641 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AHPHCOMF_01642 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AHPHCOMF_01643 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AHPHCOMF_01644 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
AHPHCOMF_01645 4.8e-16 S Protein of unknown function (DUF2969)
AHPHCOMF_01648 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
AHPHCOMF_01651 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
AHPHCOMF_01652 6.1e-70 M Pfam SNARE associated Golgi protein
AHPHCOMF_01653 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
AHPHCOMF_01654 9.3e-59 S oxidoreductase
AHPHCOMF_01655 9.7e-66 S oxidoreductase
AHPHCOMF_01656 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
AHPHCOMF_01657 6.7e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
AHPHCOMF_01658 0.0 clpE O Belongs to the ClpA ClpB family
AHPHCOMF_01659 2.6e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AHPHCOMF_01660 1.3e-34 ykuJ S protein conserved in bacteria
AHPHCOMF_01661 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
AHPHCOMF_01662 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
AHPHCOMF_01663 3.1e-78 feoA P FeoA domain protein
AHPHCOMF_01664 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
AHPHCOMF_01665 1.5e-07
AHPHCOMF_01666 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AHPHCOMF_01667 2.2e-45 K sequence-specific DNA binding
AHPHCOMF_01668 1.5e-35 yugF I carboxylic ester hydrolase activity
AHPHCOMF_01669 7.5e-23 I Alpha/beta hydrolase family
AHPHCOMF_01670 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AHPHCOMF_01671 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AHPHCOMF_01672 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
AHPHCOMF_01673 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AHPHCOMF_01675 9.2e-43 licT K transcriptional antiterminator
AHPHCOMF_01676 6.8e-53 licT K transcriptional antiterminator
AHPHCOMF_01677 1.1e-86 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AHPHCOMF_01678 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AHPHCOMF_01679 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AHPHCOMF_01680 1.2e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AHPHCOMF_01681 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AHPHCOMF_01682 6e-133 mdtG EGP Major facilitator Superfamily
AHPHCOMF_01683 9.5e-74 mdtG EGP Major facilitator Superfamily
AHPHCOMF_01684 2e-33 secG U Preprotein translocase subunit SecG
AHPHCOMF_01685 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AHPHCOMF_01686 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AHPHCOMF_01687 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHPHCOMF_01688 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
AHPHCOMF_01689 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
AHPHCOMF_01690 4.4e-183 ccpA K Catabolite control protein A
AHPHCOMF_01691 2.8e-28 yyaQ S YjbR
AHPHCOMF_01692 6.6e-101 yyaQ V Protein conserved in bacteria
AHPHCOMF_01693 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AHPHCOMF_01694 1e-78 yueI S Protein of unknown function (DUF1694)
AHPHCOMF_01695 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AHPHCOMF_01696 2e-25 WQ51_00785
AHPHCOMF_01697 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AHPHCOMF_01698 9.9e-219 ywbD 2.1.1.191 J Methyltransferase
AHPHCOMF_01699 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AHPHCOMF_01700 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AHPHCOMF_01701 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AHPHCOMF_01702 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AHPHCOMF_01703 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
AHPHCOMF_01704 3.2e-53 yheA S Belongs to the UPF0342 family
AHPHCOMF_01705 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AHPHCOMF_01706 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AHPHCOMF_01707 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AHPHCOMF_01708 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
AHPHCOMF_01709 2.6e-253 msrR K Transcriptional regulator
AHPHCOMF_01710 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
AHPHCOMF_01711 2.4e-203 I acyl-CoA dehydrogenase
AHPHCOMF_01712 4.5e-97 mip S hydroperoxide reductase activity
AHPHCOMF_01713 1.3e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHPHCOMF_01714 4.7e-106
AHPHCOMF_01715 1e-31 K Cro/C1-type HTH DNA-binding domain
AHPHCOMF_01716 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
AHPHCOMF_01717 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
AHPHCOMF_01718 1.1e-94
AHPHCOMF_01719 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AHPHCOMF_01720 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_01721 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AHPHCOMF_01722 1.7e-193 S CRISPR-associated protein Csn2 subfamily St
AHPHCOMF_01723 2.7e-146 ycgQ S TIGR03943 family
AHPHCOMF_01724 2.1e-155 XK27_03015 S permease
AHPHCOMF_01726 0.0 yhgF K Transcriptional accessory protein
AHPHCOMF_01727 9.9e-42 pspC KT PspC domain
AHPHCOMF_01728 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AHPHCOMF_01729 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AHPHCOMF_01731 2.1e-68 ytxH S General stress protein
AHPHCOMF_01733 2e-177 yegQ O Peptidase U32
AHPHCOMF_01734 3.4e-252 yegQ O Peptidase U32
AHPHCOMF_01735 8.1e-46 S CHY zinc finger
AHPHCOMF_01736 8.4e-88 bioY S biotin synthase
AHPHCOMF_01738 1.1e-33 XK27_12190 S protein conserved in bacteria
AHPHCOMF_01739 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
AHPHCOMF_01740 9.6e-12
AHPHCOMF_01741 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
AHPHCOMF_01742 0.0 L helicase
AHPHCOMF_01743 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AHPHCOMF_01744 1e-163 M LysM domain
AHPHCOMF_01745 7.6e-16
AHPHCOMF_01746 7.5e-174 S hydrolase
AHPHCOMF_01747 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
AHPHCOMF_01748 1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AHPHCOMF_01749 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
AHPHCOMF_01750 2.1e-27 P Hemerythrin HHE cation binding domain protein
AHPHCOMF_01751 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AHPHCOMF_01752 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
AHPHCOMF_01753 1.6e-21 MA20_36090 S Protein of unknown function (DUF2974)
AHPHCOMF_01754 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
AHPHCOMF_01755 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
AHPHCOMF_01756 5.9e-134 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
AHPHCOMF_01758 3e-38
AHPHCOMF_01759 1.7e-174 spd F DNA RNA non-specific endonuclease
AHPHCOMF_01760 1.7e-91 lemA S LemA family
AHPHCOMF_01761 9.3e-132 htpX O Belongs to the peptidase M48B family
AHPHCOMF_01762 4.2e-75 S Psort location CytoplasmicMembrane, score
AHPHCOMF_01763 6.2e-56 S Domain of unknown function (DUF4430)
AHPHCOMF_01764 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AHPHCOMF_01765 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
AHPHCOMF_01766 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
AHPHCOMF_01767 2e-186 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
AHPHCOMF_01768 2.2e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
AHPHCOMF_01769 3.5e-91 dps P Belongs to the Dps family
AHPHCOMF_01770 1.1e-80 perR P Belongs to the Fur family
AHPHCOMF_01771 8.4e-28 yqgQ S protein conserved in bacteria
AHPHCOMF_01772 2.2e-179 glk 2.7.1.2 G Glucokinase
AHPHCOMF_01773 0.0 typA T GTP-binding protein TypA
AHPHCOMF_01775 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AHPHCOMF_01776 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AHPHCOMF_01777 1.1e-171 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AHPHCOMF_01778 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AHPHCOMF_01779 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AHPHCOMF_01780 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AHPHCOMF_01781 1.4e-96 sepF D cell septum assembly
AHPHCOMF_01782 2.6e-34 yggT D integral membrane protein
AHPHCOMF_01783 1.2e-143 ylmH T S4 RNA-binding domain
AHPHCOMF_01784 1.8e-135 divIVA D Cell division protein DivIVA
AHPHCOMF_01785 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AHPHCOMF_01786 1.4e-212 mntH P Mn2 and Fe2 transporters of the NRAMP family
AHPHCOMF_01787 2e-45 rpmE2 J 50S ribosomal protein L31
AHPHCOMF_01788 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AHPHCOMF_01789 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
AHPHCOMF_01790 3.1e-155 gst O Glutathione S-transferase
AHPHCOMF_01791 2.1e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AHPHCOMF_01792 2.4e-112 tdk 2.7.1.21 F thymidine kinase
AHPHCOMF_01793 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AHPHCOMF_01794 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AHPHCOMF_01795 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AHPHCOMF_01796 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AHPHCOMF_01797 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
AHPHCOMF_01798 6.6e-105 pvaA M lytic transglycosylase activity
AHPHCOMF_01799 0.0 yfiB1 V abc transporter atp-binding protein
AHPHCOMF_01800 0.0 XK27_10035 V abc transporter atp-binding protein
AHPHCOMF_01801 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
AHPHCOMF_01802 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AHPHCOMF_01803 3.9e-237 dltB M Membrane protein involved in D-alanine export
AHPHCOMF_01804 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AHPHCOMF_01805 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AHPHCOMF_01806 1.2e-32 L Integrase core domain protein
AHPHCOMF_01807 8.7e-67 L Transposase and inactivated derivatives
AHPHCOMF_01808 8.3e-18 L transposase activity
AHPHCOMF_01809 5.2e-38 L Transposase
AHPHCOMF_01810 0.0 3.6.3.8 P cation transport ATPase
AHPHCOMF_01811 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
AHPHCOMF_01813 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AHPHCOMF_01814 7.3e-166 metF 1.5.1.20 E reductase
AHPHCOMF_01815 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
AHPHCOMF_01816 1.7e-94 panT S ECF transporter, substrate-specific component
AHPHCOMF_01817 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AHPHCOMF_01818 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
AHPHCOMF_01819 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AHPHCOMF_01820 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_01821 2.8e-40 T PhoQ Sensor
AHPHCOMF_01822 2.2e-43 T PhoQ Sensor
AHPHCOMF_01823 3.6e-88 T PhoQ Sensor
AHPHCOMF_01824 6.7e-122 L Helix-turn-helix domain
AHPHCOMF_01825 1.2e-165 L integrase core domain
AHPHCOMF_01826 1.1e-220 L Transposase
AHPHCOMF_01827 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
AHPHCOMF_01828 8.9e-206 potD P spermidine putrescine ABC transporter
AHPHCOMF_01829 3.1e-268 clcA P Chloride transporter, ClC family
AHPHCOMF_01830 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
AHPHCOMF_01831 2.3e-106 L Helix-turn-helix domain
AHPHCOMF_01832 9.8e-163 L Integrase core domain protein
AHPHCOMF_01833 6.2e-249 L Transposase
AHPHCOMF_01834 2.1e-30 rpsT J rRNA binding
AHPHCOMF_01835 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
AHPHCOMF_01836 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
AHPHCOMF_01837 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
AHPHCOMF_01838 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
AHPHCOMF_01839 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AHPHCOMF_01840 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AHPHCOMF_01841 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AHPHCOMF_01842 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
AHPHCOMF_01843 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
AHPHCOMF_01844 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_01845 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
AHPHCOMF_01846 1.2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
AHPHCOMF_01847 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AHPHCOMF_01848 6.8e-81 ypmB S Protein conserved in bacteria
AHPHCOMF_01849 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AHPHCOMF_01850 2.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AHPHCOMF_01851 1.5e-07
AHPHCOMF_01852 2.4e-30
AHPHCOMF_01853 3e-13
AHPHCOMF_01854 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
AHPHCOMF_01855 1.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AHPHCOMF_01856 3.7e-81 queD 4.1.2.50, 4.2.3.12 H synthase
AHPHCOMF_01857 4.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AHPHCOMF_01858 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
AHPHCOMF_01859 2.2e-19 D nuclear chromosome segregation
AHPHCOMF_01860 2e-135 yejC S cyclic nucleotide-binding protein
AHPHCOMF_01861 1.2e-163 rapZ S Displays ATPase and GTPase activities
AHPHCOMF_01862 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AHPHCOMF_01863 8.7e-162 whiA K May be required for sporulation
AHPHCOMF_01864 2.1e-185 pepD E Dipeptidase
AHPHCOMF_01865 5.4e-32 cspD K Cold shock protein domain
AHPHCOMF_01866 8e-42 K Cold-Shock Protein
AHPHCOMF_01867 3.6e-224 L Transposase, Mutator family
AHPHCOMF_01868 0.0 copB 3.6.3.4 P P-type ATPase
AHPHCOMF_01869 3.3e-222 L Transposase, Mutator family
AHPHCOMF_01870 4.4e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
AHPHCOMF_01871 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AHPHCOMF_01872 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AHPHCOMF_01873 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
AHPHCOMF_01874 6.6e-94 L Transposase
AHPHCOMF_01875 7.1e-89 L Transposase
AHPHCOMF_01876 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
AHPHCOMF_01877 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
AHPHCOMF_01878 1.2e-155 glcU U Glucose uptake
AHPHCOMF_01879 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
AHPHCOMF_01880 1.2e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
AHPHCOMF_01881 1.3e-88 XK27_10720 D peptidase activity
AHPHCOMF_01882 4e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
AHPHCOMF_01883 1.7e-08
AHPHCOMF_01885 1.1e-170 yeiH S Membrane
AHPHCOMF_01886 3e-117 mur1 NU muramidase
AHPHCOMF_01887 1.6e-19 L transposase activity
AHPHCOMF_01888 4.3e-70 L transposition
AHPHCOMF_01889 4.5e-166 cpsY K Transcriptional regulator
AHPHCOMF_01890 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AHPHCOMF_01891 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
AHPHCOMF_01892 4e-105 artQ P ABC transporter (Permease
AHPHCOMF_01893 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
AHPHCOMF_01894 1.2e-157 aatB ET ABC transporter substrate-binding protein
AHPHCOMF_01895 7.4e-144 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHPHCOMF_01896 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
AHPHCOMF_01897 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
AHPHCOMF_01898 8.8e-21
AHPHCOMF_01899 0.0 res_1 3.1.21.5 S Type III restriction
AHPHCOMF_01900 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
AHPHCOMF_01901 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AHPHCOMF_01902 2e-126 gntR1 K transcriptional
AHPHCOMF_01903 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AHPHCOMF_01904 1.4e-273 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AHPHCOMF_01905 3.1e-87 niaX
AHPHCOMF_01906 1e-17 niaR S small molecule binding protein (contains 3H domain)
AHPHCOMF_01907 2e-45 niaR S small molecule binding protein (contains 3H domain)
AHPHCOMF_01908 1.6e-128 K DNA-binding helix-turn-helix protein
AHPHCOMF_01909 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AHPHCOMF_01910 2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AHPHCOMF_01911 4.1e-167 GK ROK family
AHPHCOMF_01912 3.2e-158 dprA LU DNA protecting protein DprA
AHPHCOMF_01913 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AHPHCOMF_01914 1.4e-150 S TraX protein
AHPHCOMF_01915 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AHPHCOMF_01916 1.3e-252 T PhoQ Sensor
AHPHCOMF_01917 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AHPHCOMF_01918 4.2e-152 XK27_05470 E Methionine synthase
AHPHCOMF_01919 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AHPHCOMF_01920 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AHPHCOMF_01921 6e-43 IQ Acetoin reductase
AHPHCOMF_01922 3.9e-19 IQ Acetoin reductase
AHPHCOMF_01923 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AHPHCOMF_01924 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AHPHCOMF_01927 1.1e-212 pqqE C radical SAM domain protein
AHPHCOMF_01928 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
AHPHCOMF_01929 6.6e-61 EGP Major facilitator Superfamily
AHPHCOMF_01930 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AHPHCOMF_01931 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
AHPHCOMF_01932 4.3e-13
AHPHCOMF_01933 8e-160 L Transposase
AHPHCOMF_01934 2.8e-57 V ABC transporter (Permease

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)