ORF_ID e_value Gene_name EC_number CAZy COGs Description
NHHNPPIF_00001 8.2e-118 V ABC transporter (Permease
NHHNPPIF_00002 3.4e-113 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHHNPPIF_00003 1.6e-10
NHHNPPIF_00004 1.2e-97 K Transcriptional regulator, TetR family
NHHNPPIF_00005 1.3e-157 czcD P cation diffusion facilitator family transporter
NHHNPPIF_00006 2.3e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NHHNPPIF_00007 3.1e-195 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NHHNPPIF_00008 2.3e-07 S Hydrolases of the alpha beta superfamily
NHHNPPIF_00009 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
NHHNPPIF_00010 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
NHHNPPIF_00013 2.6e-143 2.4.2.3 F Phosphorylase superfamily
NHHNPPIF_00014 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NHHNPPIF_00015 6.1e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
NHHNPPIF_00016 2.3e-19 V drug transmembrane transporter activity
NHHNPPIF_00017 3.9e-15 dinF V Mate efflux family protein
NHHNPPIF_00019 3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NHHNPPIF_00021 6.1e-81 S TraX protein
NHHNPPIF_00022 6.5e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NHHNPPIF_00023 4.8e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NHHNPPIF_00024 1.9e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHHNPPIF_00025 9.1e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHHNPPIF_00026 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHHNPPIF_00027 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
NHHNPPIF_00028 9.7e-264 dtpT E transporter
NHHNPPIF_00029 5.6e-104 nylA 3.5.1.4 J Belongs to the amidase family
NHHNPPIF_00030 2.4e-61 yckB ET Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_00031 2.9e-58 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_00032 5.5e-53 yecS P ABC transporter (Permease
NHHNPPIF_00034 2.6e-23 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NHHNPPIF_00035 2.5e-63 yfiF3 K sequence-specific DNA binding
NHHNPPIF_00036 5.5e-24 bglC K Transcriptional regulator
NHHNPPIF_00037 8.6e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHHNPPIF_00038 4e-240 agcS E (Alanine) symporter
NHHNPPIF_00039 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NHHNPPIF_00040 2.3e-240 metY 2.5.1.49 E o-acetylhomoserine
NHHNPPIF_00041 3.2e-133 S haloacid dehalogenase-like hydrolase
NHHNPPIF_00042 3.8e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHHNPPIF_00043 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NHHNPPIF_00044 5.7e-33 M1-755 P Hemerythrin HHE cation binding domain protein
NHHNPPIF_00045 2.4e-77 XK27_04775 S hemerythrin HHE cation binding domain
NHHNPPIF_00046 3.1e-69 XK27_04775 S hemerythrin HHE cation binding domain
NHHNPPIF_00047 4.4e-49 XK27_04775 S hemerythrin HHE cation binding domain
NHHNPPIF_00048 8.4e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHHNPPIF_00049 5.5e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NHHNPPIF_00050 5.7e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHHNPPIF_00051 6.7e-44 yktA S Belongs to the UPF0223 family
NHHNPPIF_00052 4.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NHHNPPIF_00053 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NHHNPPIF_00054 1.4e-156 pstS P phosphate
NHHNPPIF_00055 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
NHHNPPIF_00056 1.5e-155 pstA P phosphate transport system permease
NHHNPPIF_00057 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHHNPPIF_00058 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHHNPPIF_00059 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
NHHNPPIF_00060 0.0 pepN 3.4.11.2 E aminopeptidase
NHHNPPIF_00061 1e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NHHNPPIF_00062 4.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
NHHNPPIF_00065 3.7e-09
NHHNPPIF_00066 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHHNPPIF_00067 1.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NHHNPPIF_00068 1.2e-62 malR K Transcriptional regulator
NHHNPPIF_00069 3.7e-46 malR K Transcriptional regulator
NHHNPPIF_00070 4.2e-17 malX G ABC transporter
NHHNPPIF_00071 9.1e-168 malX G ABC transporter
NHHNPPIF_00072 1.1e-202 malF P ABC transporter (Permease
NHHNPPIF_00073 4.2e-10 L transposase activity
NHHNPPIF_00074 3.6e-39 L Transposase
NHHNPPIF_00075 0.0 3.6.3.8 P cation transport ATPase
NHHNPPIF_00076 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NHHNPPIF_00078 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHHNPPIF_00079 1.1e-164 metF 1.5.1.20 C reductase
NHHNPPIF_00080 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NHHNPPIF_00081 1.1e-93 panT S ECF transporter, substrate-specific component
NHHNPPIF_00082 1.4e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHHNPPIF_00083 2.8e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NHHNPPIF_00084 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NHHNPPIF_00085 1.2e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_00086 1e-29 T PhoQ Sensor
NHHNPPIF_00087 4.1e-43 T PhoQ Sensor
NHHNPPIF_00088 1.7e-120 T PhoQ Sensor
NHHNPPIF_00089 5.1e-122 L Transposase
NHHNPPIF_00090 1.2e-165 L integrase core domain
NHHNPPIF_00091 1.3e-29 rpsT J rRNA binding
NHHNPPIF_00092 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
NHHNPPIF_00093 3.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
NHHNPPIF_00094 2.3e-26 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NHHNPPIF_00095 3e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
NHHNPPIF_00096 6.1e-94 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NHHNPPIF_00097 1.1e-10 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
NHHNPPIF_00098 2.9e-30 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHHNPPIF_00099 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHHNPPIF_00100 4.7e-57 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NHHNPPIF_00101 1.6e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NHHNPPIF_00102 6.4e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NHHNPPIF_00103 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00104 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00105 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NHHNPPIF_00106 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NHHNPPIF_00107 3.1e-81 ypmB S Protein conserved in bacteria
NHHNPPIF_00108 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NHHNPPIF_00109 4.2e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHHNPPIF_00110 2.5e-15
NHHNPPIF_00111 6.8e-54 L Transposase
NHHNPPIF_00112 5.4e-22
NHHNPPIF_00113 1.5e-12
NHHNPPIF_00116 6.3e-28 Q the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_00117 3.7e-31 Q the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_00118 3.2e-17 S Domain of unknown function (DUF4649)
NHHNPPIF_00119 5.4e-173 XK27_08835 S ABC transporter substrate binding protein
NHHNPPIF_00120 2e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00121 4.4e-135 XK27_08845 S abc transporter atp-binding protein
NHHNPPIF_00122 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHHNPPIF_00123 1.1e-149 estA CE1 S Putative esterase
NHHNPPIF_00124 3e-125 XK27_08875 O Zinc-dependent metalloprotease
NHHNPPIF_00125 3.3e-14 XK27_08880
NHHNPPIF_00126 1e-75 fld C Flavodoxin
NHHNPPIF_00127 1.7e-282 clcA P Chloride transporter, ClC family
NHHNPPIF_00128 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NHHNPPIF_00129 2.1e-219 XK27_05110 P chloride
NHHNPPIF_00130 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHHNPPIF_00132 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
NHHNPPIF_00133 3e-162 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHHNPPIF_00134 2.7e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NHHNPPIF_00135 7.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHHNPPIF_00136 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHHNPPIF_00137 6e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHHNPPIF_00138 1.3e-36 5.1.3.2 GM Psort location CytoplasmicMembrane, score
NHHNPPIF_00139 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHHNPPIF_00141 1.1e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHHNPPIF_00142 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
NHHNPPIF_00143 7e-124 endA F DNA RNA non-specific endonuclease
NHHNPPIF_00144 3.8e-111 tcyB_2 P ABC transporter (permease)
NHHNPPIF_00145 8e-115 gltJ P ABC transporter (Permease
NHHNPPIF_00146 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHHNPPIF_00147 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
NHHNPPIF_00148 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_00149 5.8e-247 vicK 2.7.13.3 T Histidine kinase
NHHNPPIF_00150 3.9e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NHHNPPIF_00151 4.2e-34 F Protein of unknown function (DUF454)
NHHNPPIF_00152 2.6e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NHHNPPIF_00153 9.2e-147 yidA S hydrolases of the HAD superfamily
NHHNPPIF_00154 2.4e-44 XK27_00115 2.3.1.128 K acetyltransferase
NHHNPPIF_00155 3.4e-67 ywiB S Domain of unknown function (DUF1934)
NHHNPPIF_00156 0.0 pacL 3.6.3.8 P cation transport ATPase
NHHNPPIF_00157 2e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NHHNPPIF_00158 9.2e-183 yjjH S Calcineurin-like phosphoesterase
NHHNPPIF_00159 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHHNPPIF_00160 1.8e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHHNPPIF_00161 5.5e-124 ftsE D cell division ATP-binding protein FtsE
NHHNPPIF_00162 5.2e-162 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NHHNPPIF_00163 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHHNPPIF_00164 8.1e-176 yubA S permease
NHHNPPIF_00165 2.4e-223 G COG0457 FOG TPR repeat
NHHNPPIF_00166 6e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NHHNPPIF_00167 6.5e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHHNPPIF_00168 1.2e-88 ebsA S Family of unknown function (DUF5322)
NHHNPPIF_00169 2.8e-18 M LysM domain
NHHNPPIF_00170 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NHHNPPIF_00171 5.9e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHHNPPIF_00172 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NHHNPPIF_00173 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHHNPPIF_00174 1.3e-84 L Transposase
NHHNPPIF_00175 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
NHHNPPIF_00176 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHHNPPIF_00177 1e-229 cinA 3.5.1.42 S Belongs to the CinA family
NHHNPPIF_00178 7.8e-105 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NHHNPPIF_00179 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHHNPPIF_00181 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHHNPPIF_00183 7.9e-68 K LytTr DNA-binding domain
NHHNPPIF_00184 2.3e-78 S Protein of unknown function (DUF3021)
NHHNPPIF_00185 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHHNPPIF_00186 1.5e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NHHNPPIF_00187 8.2e-70 argR K Regulates arginine biosynthesis genes
NHHNPPIF_00188 1.1e-52
NHHNPPIF_00190 2.8e-08
NHHNPPIF_00193 3.8e-295 S DNA primase
NHHNPPIF_00194 1.7e-154 KL Phage plasmid primase P4 family
NHHNPPIF_00195 9e-22
NHHNPPIF_00200 5.5e-17 K TRANSCRIPTIONal
NHHNPPIF_00201 6e-39 K Helix-turn-helix
NHHNPPIF_00202 6.7e-215 sip L Belongs to the 'phage' integrase family
NHHNPPIF_00203 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHHNPPIF_00204 3.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHHNPPIF_00205 1.2e-32
NHHNPPIF_00206 2e-140 1.1.1.169 H Ketopantoate reductase
NHHNPPIF_00207 8.5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHHNPPIF_00208 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHHNPPIF_00209 2e-241 purD 6.3.4.13 F Belongs to the GARS family
NHHNPPIF_00210 7.5e-160 S CHAP domain
NHHNPPIF_00211 3.8e-31 L Integrase core domain protein
NHHNPPIF_00212 3.4e-24 L Transposase
NHHNPPIF_00213 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHHNPPIF_00214 9.5e-55 yabA L Involved in initiation control of chromosome replication
NHHNPPIF_00215 8e-135 yaaT S stage 0 sporulation protein
NHHNPPIF_00216 1.1e-156 holB 2.7.7.7 L dna polymerase iii
NHHNPPIF_00217 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHHNPPIF_00218 3.4e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHHNPPIF_00219 3.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHHNPPIF_00220 7.5e-228 ftsW D Belongs to the SEDS family
NHHNPPIF_00221 2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NHHNPPIF_00222 6.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHHNPPIF_00223 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHHNPPIF_00224 2.5e-278 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHHNPPIF_00225 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHHNPPIF_00226 2.3e-76 atpF C ATP synthase F(0) sector subunit b
NHHNPPIF_00227 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
NHHNPPIF_00228 1.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHHNPPIF_00229 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHHNPPIF_00230 8.1e-69 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHHNPPIF_00231 8.3e-105 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHHNPPIF_00232 8.9e-14 coiA 3.6.4.12 S Competence protein
NHHNPPIF_00233 2.6e-16 T peptidase
NHHNPPIF_00234 1e-151 rarD S Transporter
NHHNPPIF_00235 4.2e-150 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHHNPPIF_00236 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NHHNPPIF_00237 2.5e-129 yxkH G deacetylase
NHHNPPIF_00238 5.3e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NHHNPPIF_00239 1.2e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NHHNPPIF_00240 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHHNPPIF_00241 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHHNPPIF_00242 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NHHNPPIF_00243 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHHNPPIF_00244 1.3e-30 3.4.17.14, 3.5.1.28 NU amidase activity
NHHNPPIF_00245 3.4e-41 3.4.17.14, 3.5.1.28 NU amidase activity
NHHNPPIF_00246 2.5e-146 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NHHNPPIF_00247 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHHNPPIF_00248 8.9e-163 S Uncharacterised protein family (UPF0236)
NHHNPPIF_00249 9.5e-126 S Fic/DOC family
NHHNPPIF_00251 4.5e-114 D CobQ CobB MinD ParA nucleotide binding domain protein
NHHNPPIF_00253 1.3e-73 tnpR L Resolvase, N terminal domain
NHHNPPIF_00256 1.4e-183 U Relaxase/Mobilisation nuclease domain
NHHNPPIF_00257 4.6e-25 tatA U protein secretion
NHHNPPIF_00258 4.4e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHHNPPIF_00259 3e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NHHNPPIF_00260 5.6e-233 ycdB P peroxidase
NHHNPPIF_00261 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
NHHNPPIF_00262 1.2e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00263 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00264 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00265 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00266 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00267 1.6e-185 3.5.1.28 M GBS Bsp-like repeat
NHHNPPIF_00268 1.9e-65 3.2.1.17 M lysozyme activity
NHHNPPIF_00269 9.9e-12 3.5.1.28 NU amidase activity
NHHNPPIF_00270 0.0 lpdA 1.8.1.4 C Dehydrogenase
NHHNPPIF_00271 1.3e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHHNPPIF_00272 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHHNPPIF_00273 1.7e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NHHNPPIF_00274 0.0 S the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_00275 1.8e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHHNPPIF_00276 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHHNPPIF_00277 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHHNPPIF_00278 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NHHNPPIF_00279 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
NHHNPPIF_00280 4.1e-127 3.4.16.4 M Belongs to the peptidase S11 family
NHHNPPIF_00281 1.2e-157 rssA S Phospholipase, patatin family
NHHNPPIF_00282 1.8e-69 estA E GDSL-like protein
NHHNPPIF_00283 3.4e-29 estA E Lysophospholipase L1 and related esterases
NHHNPPIF_00284 7e-292 S unusual protein kinase
NHHNPPIF_00285 4.9e-39 S granule-associated protein
NHHNPPIF_00286 4.6e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHHNPPIF_00287 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHHNPPIF_00288 1.3e-199 S hmm pf01594
NHHNPPIF_00289 2.5e-101 G Belongs to the phosphoglycerate mutase family
NHHNPPIF_00290 3.7e-60 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
NHHNPPIF_00291 1.1e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NHHNPPIF_00292 2.2e-94 V VanZ like family
NHHNPPIF_00293 5.1e-21 L overlaps another CDS with the same product name
NHHNPPIF_00294 1.7e-44 K helix_turn_helix, Arsenical Resistance Operon Repressor
NHHNPPIF_00295 6.3e-160 yrdR EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHHNPPIF_00296 1.2e-71 2.7.7.12 C Domain of unknown function (DUF4931)
NHHNPPIF_00297 6.8e-153 S metal-dependent hydrolase with the TIM-barrel fold
NHHNPPIF_00298 7.7e-123 dlpA H Methyltransferase
NHHNPPIF_00299 4e-209 dlpA 1.1.1.85 CE Tartrate dehydrogenase
NHHNPPIF_00301 1.3e-160 4.1.3.39 E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds
NHHNPPIF_00302 2.3e-48 L transposition
NHHNPPIF_00303 1e-16 L Transposase
NHHNPPIF_00304 1.2e-61 L Transposase
NHHNPPIF_00305 1.1e-284 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHHNPPIF_00306 3.2e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHHNPPIF_00307 7.5e-141 cmpC S abc transporter atp-binding protein
NHHNPPIF_00308 0.0 WQ51_06230 S ABC transporter substrate binding protein
NHHNPPIF_00309 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHHNPPIF_00310 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NHHNPPIF_00311 5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
NHHNPPIF_00312 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHHNPPIF_00313 2.4e-48 yajC U protein transport
NHHNPPIF_00314 1.9e-127 yeeN K transcriptional regulatory protein
NHHNPPIF_00315 6.9e-256 pgi 5.3.1.9 G Belongs to the GPI family
NHHNPPIF_00316 9.8e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
NHHNPPIF_00317 4.2e-257 ptsG 2.7.1.199, 2.7.1.208 G pts system
NHHNPPIF_00318 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
NHHNPPIF_00319 1.3e-64 ptsG 2.7.1.199, 2.7.1.208 G pts system
NHHNPPIF_00320 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NHHNPPIF_00321 1.9e-128 adcB P ABC transporter (Permease
NHHNPPIF_00322 2.2e-136 adcC P ABC transporter, ATP-binding protein
NHHNPPIF_00323 3.1e-72 adcR K transcriptional
NHHNPPIF_00324 1.9e-223 EGP Major facilitator Superfamily
NHHNPPIF_00325 0.0 KLT serine threonine protein kinase
NHHNPPIF_00326 3e-127 K sequence-specific DNA binding
NHHNPPIF_00327 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHHNPPIF_00328 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHHNPPIF_00329 7.4e-10
NHHNPPIF_00331 1.4e-87 oppF P Belongs to the ABC transporter superfamily
NHHNPPIF_00332 2.2e-61 oppF P Belongs to the ABC transporter superfamily
NHHNPPIF_00333 1.1e-43 oppD P Belongs to the ABC transporter superfamily
NHHNPPIF_00334 1.1e-68 oppD P Belongs to the ABC transporter superfamily
NHHNPPIF_00335 2.5e-32 oppD P Belongs to the ABC transporter superfamily
NHHNPPIF_00336 3e-27 oppD P Belongs to the ABC transporter superfamily
NHHNPPIF_00337 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHHNPPIF_00338 2.5e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHHNPPIF_00340 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHHNPPIF_00341 1.1e-125 oppA E ABC transporter substrate-binding protein
NHHNPPIF_00342 9.7e-19 oppA E ABC transporter substrate-binding protein
NHHNPPIF_00343 2.2e-273 sufB O assembly protein SufB
NHHNPPIF_00344 2.1e-73 nifU C SUF system FeS assembly protein, NifU family
NHHNPPIF_00345 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHHNPPIF_00346 6.3e-235 sufD O assembly protein SufD
NHHNPPIF_00347 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NHHNPPIF_00348 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
NHHNPPIF_00349 8.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHHNPPIF_00350 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHHNPPIF_00351 1.8e-276 glnP P ABC transporter
NHHNPPIF_00352 1e-123 glnQ E abc transporter atp-binding protein
NHHNPPIF_00355 5e-94 V VanZ like family
NHHNPPIF_00356 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHHNPPIF_00357 7.9e-200 yhjX P Major Facilitator
NHHNPPIF_00358 4.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NHHNPPIF_00359 1.2e-111 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHHNPPIF_00360 7.3e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHHNPPIF_00361 7.7e-40 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NHHNPPIF_00362 2.3e-18 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NHHNPPIF_00363 3e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NHHNPPIF_00364 2e-08 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NHHNPPIF_00365 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHHNPPIF_00366 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHHNPPIF_00367 5.3e-83 nrdI F Belongs to the NrdI family
NHHNPPIF_00368 1e-241 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NHHNPPIF_00369 1.5e-97 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NHHNPPIF_00370 1.5e-35 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NHHNPPIF_00371 3.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHHNPPIF_00372 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
NHHNPPIF_00373 7.3e-39 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NHHNPPIF_00374 1.7e-167 L Recombinase
NHHNPPIF_00375 1.8e-189 L Resolvase, N-terminal domain protein
NHHNPPIF_00376 9.2e-236 L Psort location Cytoplasmic, score
NHHNPPIF_00378 6.1e-19 K Psort location Cytoplasmic, score
NHHNPPIF_00380 5.1e-77 S CAAX protease self-immunity
NHHNPPIF_00381 1.2e-47 blpT
NHHNPPIF_00382 9.3e-75 L Transposase and inactivated derivatives
NHHNPPIF_00383 4.1e-33 L Integrase core domain
NHHNPPIF_00384 1.4e-75 L transposase activity
NHHNPPIF_00386 1.6e-12 S Bacteriocin class II with double-glycine leader peptide
NHHNPPIF_00387 4.3e-18 comA V Papain-like cysteine protease AvrRpt2
NHHNPPIF_00388 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_00389 1.3e-145 mesE M HlyD family secretion protein
NHHNPPIF_00391 4.5e-122 blpH 2.7.13.3 T GHKL domain
NHHNPPIF_00392 2.6e-103 blpR KT LytTr DNA-binding domain
NHHNPPIF_00393 3.3e-21 blpS KT phosphorelay signal transduction system
NHHNPPIF_00394 1.2e-19
NHHNPPIF_00395 4.1e-299 U relaxase
NHHNPPIF_00396 2.1e-50 S Bacterial mobilisation protein (MobC)
NHHNPPIF_00397 1.7e-52
NHHNPPIF_00398 8.9e-49 V Restriction endonuclease
NHHNPPIF_00399 2.3e-190 vrlS L DEAD DEAH box helicase
NHHNPPIF_00400 5.8e-40 vrlR S Domain of unknown function (DUF1837)
NHHNPPIF_00401 2.6e-130 2.7.1.176 O Zeta toxin
NHHNPPIF_00402 1.1e-281 L Transposase DDE domain
NHHNPPIF_00403 2.3e-39
NHHNPPIF_00404 2.9e-58 XK27_10880
NHHNPPIF_00405 1.1e-17 XK27_10875
NHHNPPIF_00406 1.3e-149 L Toprim-like
NHHNPPIF_00407 2.7e-11 L Protein of unknown function (DUF3991)
NHHNPPIF_00408 9.9e-104 XK27_10865
NHHNPPIF_00409 3.5e-18 V endonuclease activity
NHHNPPIF_00410 5.3e-45 L DNA synthesis involved in DNA repair
NHHNPPIF_00411 2.3e-31
NHHNPPIF_00412 2.4e-44
NHHNPPIF_00413 8.1e-241 XK27_00500 L SNF2 family N-terminal domain
NHHNPPIF_00414 0.0 L reverse transcriptase
NHHNPPIF_00415 0.0 XK27_00500 L SNF2 family N-terminal domain
NHHNPPIF_00416 7.8e-89 XK27_00505
NHHNPPIF_00417 5.1e-11 XK27_00510
NHHNPPIF_00418 0.0 XK27_00515 D Glucan-binding protein C
NHHNPPIF_00419 6.8e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
NHHNPPIF_00420 6e-149 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NHHNPPIF_00421 0.0 XK27_00530 S CHAP domain
NHHNPPIF_00422 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
NHHNPPIF_00423 1.5e-61 XK27_00550 S PrgI family protein
NHHNPPIF_00424 2.6e-139
NHHNPPIF_00425 9.2e-34 XK27_00560
NHHNPPIF_00426 0.0 traG U Type IV secretory system Conjugative DNA transfer
NHHNPPIF_00427 1.3e-79 XK27_00570
NHHNPPIF_00428 1e-91 ypbD S CAAX protease self-immunity
NHHNPPIF_00429 1.5e-36 XK27_00580
NHHNPPIF_00430 1e-63 XK27_00585 P arsenate reductase (glutaredoxin) activity
NHHNPPIF_00431 1.4e-74 XK27_00590
NHHNPPIF_00432 3.3e-258 hpaIIM 2.1.1.37 H cytosine-specific methyltransferase
NHHNPPIF_00433 5.8e-141 repA S Replication initiator protein A (RepA) N-terminus
NHHNPPIF_00434 5.2e-20
NHHNPPIF_00435 3.4e-19 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NHHNPPIF_00436 4.2e-83 XK27_03960 S Protein of unknown function (DUF3013)
NHHNPPIF_00437 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHHNPPIF_00438 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHHNPPIF_00439 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHHNPPIF_00440 1.6e-146 ykuT M mechanosensitive ion channel
NHHNPPIF_00441 1.6e-77 sigH K DNA-templated transcription, initiation
NHHNPPIF_00442 2e-31 XK27_08085
NHHNPPIF_00443 8.4e-88 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NHHNPPIF_00444 7.9e-10 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NHHNPPIF_00445 5.8e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NHHNPPIF_00446 5.8e-120 ylfI S tigr01906
NHHNPPIF_00447 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHHNPPIF_00448 5.7e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
NHHNPPIF_00449 6.9e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NHHNPPIF_00450 4.6e-18 L COG2801 Transposase and inactivated derivatives
NHHNPPIF_00451 1.6e-112 K sequence-specific DNA binding
NHHNPPIF_00452 2e-11 C Arylsulfatase regulator (Fe-S oxidoreductase)
NHHNPPIF_00455 3.5e-106 MA20_06410 E LysE type translocator
NHHNPPIF_00456 8.6e-70 IQ PFAM AMP-dependent synthetase and ligase
NHHNPPIF_00457 1.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHHNPPIF_00458 0.0 comEC S Competence protein ComEC
NHHNPPIF_00459 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NHHNPPIF_00460 1.7e-142 plsC 2.3.1.51 I Acyltransferase
NHHNPPIF_00461 1.8e-140 nodB3 G deacetylase
NHHNPPIF_00462 7.1e-141 yabB 2.1.1.223 L Methyltransferase
NHHNPPIF_00463 1e-41 yazA L endonuclease containing a URI domain
NHHNPPIF_00464 6.9e-223 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHHNPPIF_00465 1.5e-153 corA P CorA-like protein
NHHNPPIF_00466 2.5e-62 yjqA S Bacterial PH domain
NHHNPPIF_00467 2.3e-99 thiT S Thiamine transporter
NHHNPPIF_00468 1.4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NHHNPPIF_00469 5.2e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHHNPPIF_00470 3.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NHHNPPIF_00471 8.6e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHHNPPIF_00472 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHHNPPIF_00473 4.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NHHNPPIF_00474 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHHNPPIF_00475 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHHNPPIF_00476 1e-142 recO L Involved in DNA repair and RecF pathway recombination
NHHNPPIF_00477 5.5e-217 araT 2.6.1.1 E Aminotransferase
NHHNPPIF_00478 7.3e-26
NHHNPPIF_00479 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHHNPPIF_00480 4.1e-59 usp 3.5.1.28 CBM50 S CHAP domain
NHHNPPIF_00481 2.4e-90 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHHNPPIF_00482 4.9e-122 comFC S Competence protein
NHHNPPIF_00483 2e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NHHNPPIF_00484 6.3e-111 yvyE 3.4.13.9 S YigZ family
NHHNPPIF_00485 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHHNPPIF_00486 9.3e-42 acuB S IMP dehydrogenase activity
NHHNPPIF_00487 1e-39 acuB S CBS domain
NHHNPPIF_00488 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NHHNPPIF_00489 6.2e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NHHNPPIF_00490 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00491 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
NHHNPPIF_00492 9.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NHHNPPIF_00493 7.1e-46 ylbG S UPF0298 protein
NHHNPPIF_00494 1.3e-73 ylbF S Belongs to the UPF0342 family
NHHNPPIF_00495 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHHNPPIF_00496 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHHNPPIF_00497 8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
NHHNPPIF_00498 2.8e-221 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NHHNPPIF_00499 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
NHHNPPIF_00500 2.3e-91 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NHHNPPIF_00501 1e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NHHNPPIF_00502 7.9e-274 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHHNPPIF_00503 3.6e-219 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NHHNPPIF_00505 1.8e-45 yvdD 3.2.2.10 S Belongs to the LOG family
NHHNPPIF_00506 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHHNPPIF_00507 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHHNPPIF_00508 1.4e-41 ylxQ J ribosomal protein
NHHNPPIF_00509 3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NHHNPPIF_00510 3.1e-212 nusA K Participates in both transcription termination and antitermination
NHHNPPIF_00511 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
NHHNPPIF_00512 1.5e-217 brpA K Transcriptional
NHHNPPIF_00513 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
NHHNPPIF_00514 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NHHNPPIF_00515 3e-241 pbuO S permease
NHHNPPIF_00516 5.6e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NHHNPPIF_00517 4.9e-139 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NHHNPPIF_00518 2.4e-173 manL 2.7.1.191 G pts system
NHHNPPIF_00519 3.9e-116 manM G pts system
NHHNPPIF_00520 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
NHHNPPIF_00521 4.2e-62 manO S protein conserved in bacteria
NHHNPPIF_00522 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHHNPPIF_00525 3.9e-17 L Psort location Cytoplasmic, score
NHHNPPIF_00527 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHHNPPIF_00528 1e-33 L Transposase
NHHNPPIF_00529 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHHNPPIF_00530 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
NHHNPPIF_00531 3.8e-205 EGP Transmembrane secretion effector
NHHNPPIF_00532 2.3e-31 L Integrase core domain protein
NHHNPPIF_00533 8.2e-27 S Membrane
NHHNPPIF_00534 1.7e-99
NHHNPPIF_00535 1.8e-23 S Small integral membrane protein
NHHNPPIF_00536 6.5e-83 M Protein conserved in bacteria
NHHNPPIF_00537 9.2e-11 K CsbD-like
NHHNPPIF_00538 3.7e-27 S Membrane
NHHNPPIF_00539 1.7e-99
NHHNPPIF_00540 1.8e-23 S Small integral membrane protein
NHHNPPIF_00541 6.5e-83 M Protein conserved in bacteria
NHHNPPIF_00542 9.2e-11 K CsbD-like
NHHNPPIF_00543 1.1e-32 L Transposase
NHHNPPIF_00544 8.3e-89 yrdC 3.5.1.19 Q isochorismatase
NHHNPPIF_00545 1.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NHHNPPIF_00546 8.9e-167 dnaI L Primosomal protein DnaI
NHHNPPIF_00547 2.7e-216 dnaB L Replication initiation and membrane attachment
NHHNPPIF_00548 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHHNPPIF_00549 1.2e-275 T PhoQ Sensor
NHHNPPIF_00550 3.9e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_00551 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
NHHNPPIF_00552 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NHHNPPIF_00553 2.2e-241 P COG0168 Trk-type K transport systems, membrane components
NHHNPPIF_00554 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NHHNPPIF_00555 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
NHHNPPIF_00556 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHHNPPIF_00557 1.2e-149 cbiQ P cobalt transport
NHHNPPIF_00558 0.0 ykoD P abc transporter atp-binding protein
NHHNPPIF_00559 8e-94 S UPF0397 protein
NHHNPPIF_00560 4.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NHHNPPIF_00561 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NHHNPPIF_00562 8.8e-98 metI P ABC transporter (Permease
NHHNPPIF_00563 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHHNPPIF_00564 2.1e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NHHNPPIF_00565 4.8e-76 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NHHNPPIF_00566 2.5e-77 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NHHNPPIF_00567 2.3e-162 metQ M Belongs to the NlpA lipoprotein family
NHHNPPIF_00568 5.9e-25 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHHNPPIF_00569 2.1e-82 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00570 6.6e-84 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00571 3.6e-117 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NHHNPPIF_00572 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NHHNPPIF_00573 5e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NHHNPPIF_00574 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NHHNPPIF_00575 1.3e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHHNPPIF_00578 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHHNPPIF_00579 3.8e-174 vraS 2.7.13.3 T Histidine kinase
NHHNPPIF_00580 9.1e-119 yvqF KT membrane
NHHNPPIF_00581 5.3e-307 prkC 2.7.11.1 KLT serine threonine protein kinase
NHHNPPIF_00582 2.9e-131 stp 3.1.3.16 T phosphatase
NHHNPPIF_00583 2.2e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHHNPPIF_00584 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHHNPPIF_00585 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHHNPPIF_00586 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NHHNPPIF_00587 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NHHNPPIF_00588 6.7e-214 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHHNPPIF_00589 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
NHHNPPIF_00590 2.1e-148 supH S overlaps another CDS with the same product name
NHHNPPIF_00591 8.6e-63 yvoA_1 K Transcriptional
NHHNPPIF_00592 9.8e-121 skfE V abc transporter atp-binding protein
NHHNPPIF_00593 5.6e-133 V ATPase activity
NHHNPPIF_00594 6.6e-40 oppF P Belongs to the ABC transporter superfamily
NHHNPPIF_00595 3.5e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NHHNPPIF_00596 1.9e-15 M LysM domain
NHHNPPIF_00597 2.4e-58 M LysM domain
NHHNPPIF_00598 3.1e-20
NHHNPPIF_00599 6.4e-173 S hydrolase
NHHNPPIF_00600 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
NHHNPPIF_00601 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHHNPPIF_00602 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
NHHNPPIF_00603 2.7e-27 P Hemerythrin HHE cation binding domain protein
NHHNPPIF_00604 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHHNPPIF_00605 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
NHHNPPIF_00606 7.9e-37 MA20_36090 S Protein of unknown function (DUF2974)
NHHNPPIF_00607 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
NHHNPPIF_00608 3.7e-48 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHHNPPIF_00609 1.7e-70 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHHNPPIF_00610 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NHHNPPIF_00611 8.7e-216 prrC S AAA domain
NHHNPPIF_00612 5e-125 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
NHHNPPIF_00613 4.8e-105
NHHNPPIF_00614 7.5e-135 S Protein conserved in bacteria
NHHNPPIF_00615 2.4e-303 hsdM 2.1.1.72 V type I restriction-modification system
NHHNPPIF_00616 1.2e-49 S PD-(D/E)XK nuclease family transposase
NHHNPPIF_00617 1.1e-90 S double-stranded DNA endodeoxyribonuclease activity
NHHNPPIF_00618 5.1e-163 spd F DNA RNA non-specific endonuclease
NHHNPPIF_00619 9e-93 lemA S LemA family
NHHNPPIF_00620 6.4e-133 htpX O Belongs to the peptidase M48B family
NHHNPPIF_00621 4.2e-75 S Psort location CytoplasmicMembrane, score
NHHNPPIF_00622 6.2e-56 S Domain of unknown function (DUF4430)
NHHNPPIF_00623 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NHHNPPIF_00624 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
NHHNPPIF_00625 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NHHNPPIF_00626 5.3e-21 L Transposase
NHHNPPIF_00627 4.2e-192 wbbI M transferase activity, transferring glycosyl groups
NHHNPPIF_00628 1e-212 glf 5.4.99.9 M UDP-galactopyranose mutase
NHHNPPIF_00629 5.4e-243 epsU S Polysaccharide biosynthesis protein
NHHNPPIF_00630 6.3e-173
NHHNPPIF_00631 7.1e-149 M Glycosyltransferase like family 2
NHHNPPIF_00632 8.6e-123 M Glycosyltransferase, group 2 family protein
NHHNPPIF_00634 4.6e-73 Z012_10770 M Domain of unknown function (DUF1919)
NHHNPPIF_00635 4.3e-206 wcoF M Glycosyltransferase, group 1 family protein
NHHNPPIF_00636 5e-218 rgpAc GT4 M group 1 family protein
NHHNPPIF_00637 1e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NHHNPPIF_00638 2.5e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
NHHNPPIF_00639 1.7e-109 cps4C M biosynthesis protein
NHHNPPIF_00640 1.9e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NHHNPPIF_00641 2.1e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NHHNPPIF_00642 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NHHNPPIF_00643 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
NHHNPPIF_00644 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
NHHNPPIF_00645 9e-88 clcA_2 P chloride
NHHNPPIF_00646 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NHHNPPIF_00647 8.1e-41 S Protein of unknown function (DUF1697)
NHHNPPIF_00648 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHHNPPIF_00649 5e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHHNPPIF_00651 5.7e-08 V Glucan-binding protein C
NHHNPPIF_00652 2.7e-22 V Glucan-binding protein C
NHHNPPIF_00653 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
NHHNPPIF_00654 9e-275 pepV 3.5.1.18 E Dipeptidase
NHHNPPIF_00655 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NHHNPPIF_00656 2e-41 XK27_03610 K Gnat family
NHHNPPIF_00657 1e-33 L Transposase
NHHNPPIF_00658 3.3e-68 L transposition
NHHNPPIF_00659 8.5e-275 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHHNPPIF_00660 0.0 L Toprim-like
NHHNPPIF_00662 3.3e-35 S Bacterial mobilisation protein (MobC)
NHHNPPIF_00663 1.3e-24 WQ51_00785
NHHNPPIF_00664 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHHNPPIF_00665 2.6e-219 ywbD 2.1.1.191 J Methyltransferase
NHHNPPIF_00666 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHHNPPIF_00667 1.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHHNPPIF_00668 1.9e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHHNPPIF_00669 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHHNPPIF_00670 1.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NHHNPPIF_00671 3.2e-53 yheA S Belongs to the UPF0342 family
NHHNPPIF_00672 8.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NHHNPPIF_00673 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHHNPPIF_00674 2.5e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHHNPPIF_00675 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
NHHNPPIF_00676 9e-238 msrR K Transcriptional regulator
NHHNPPIF_00677 1.6e-155 ydiA P C4-dicarboxylate transporter malic acid transport protein
NHHNPPIF_00678 1.3e-201 I acyl-CoA dehydrogenase
NHHNPPIF_00679 4.5e-97 mip S hydroperoxide reductase activity
NHHNPPIF_00680 1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHHNPPIF_00681 1.7e-54 J Acetyltransferase (GNAT) domain
NHHNPPIF_00682 5.7e-95
NHHNPPIF_00683 1.9e-59 S Uncharacterised lipoprotein family
NHHNPPIF_00684 1.5e-75 tspO T TspO/MBR family
NHHNPPIF_00685 2.6e-44 pepD E Dipeptidase
NHHNPPIF_00686 1.2e-103 pepD E Dipeptidase
NHHNPPIF_00687 1.9e-161 whiA K May be required for sporulation
NHHNPPIF_00688 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NHHNPPIF_00689 4.5e-163 rapZ S Displays ATPase and GTPase activities
NHHNPPIF_00690 1.5e-135 yejC S cyclic nucleotide-binding protein
NHHNPPIF_00691 4.2e-18 D nuclear chromosome segregation
NHHNPPIF_00692 1.2e-157 C Arylsulfatase regulator (Fe-S oxidoreductase)
NHHNPPIF_00693 1.1e-196 V (ABC) transporter
NHHNPPIF_00694 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
NHHNPPIF_00695 1.4e-273 S Protein of unknown function (DUF3114)
NHHNPPIF_00697 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NHHNPPIF_00698 2.1e-39 V (ABC) transporter
NHHNPPIF_00699 3.6e-100 V abc transporter atp-binding protein
NHHNPPIF_00700 3.6e-258 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NHHNPPIF_00701 6.7e-24 L transposition
NHHNPPIF_00702 1.2e-08 L Integrase core domain protein
NHHNPPIF_00703 2.3e-150 galR K Transcriptional regulator
NHHNPPIF_00704 1.7e-21 galR K Transcriptional regulator
NHHNPPIF_00705 2e-219 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHHNPPIF_00706 2.8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NHHNPPIF_00707 4.3e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHHNPPIF_00708 8.7e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NHHNPPIF_00709 0.0 lacS G transporter
NHHNPPIF_00710 0.0 lacL 3.2.1.23 G -beta-galactosidase
NHHNPPIF_00711 7.6e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHHNPPIF_00712 0.0 sbcC L ATPase involved in DNA repair
NHHNPPIF_00713 1e-31
NHHNPPIF_00714 3.1e-44 L COG2963 Transposase and inactivated derivatives
NHHNPPIF_00715 5.9e-62 L Transposase and inactivated derivatives
NHHNPPIF_00716 1.5e-39 L transposition
NHHNPPIF_00725 7.4e-115 M Bacteriophage peptidoglycan hydrolase
NHHNPPIF_00726 2.8e-22 S COG5546 Small integral membrane protein
NHHNPPIF_00730 4e-308 S N-acetylmuramoyl-L-alanine amidase activity
NHHNPPIF_00731 0.0 S peptidoglycan catabolic process
NHHNPPIF_00732 1.6e-171 S Phage tail protein
NHHNPPIF_00733 2.6e-193 S peptidoglycan catabolic process
NHHNPPIF_00735 5e-57 S Pfam:Phage_TAC_12
NHHNPPIF_00736 3.4e-75 S Phage major tail protein 2
NHHNPPIF_00737 8.2e-61
NHHNPPIF_00738 4e-43 S exonuclease activity
NHHNPPIF_00740 2.1e-36 S Phage gp6-like head-tail connector protein
NHHNPPIF_00742 7.6e-178 S Phage major capsid protein E
NHHNPPIF_00743 2.4e-14
NHHNPPIF_00744 3.5e-10 S Domain of unknown function (DUF4355)
NHHNPPIF_00745 1.8e-111 S Phage Mu protein F like protein
NHHNPPIF_00746 5.3e-249 S Phage portal protein, SPP1 Gp6-like
NHHNPPIF_00747 4.9e-240 S Terminase-like family
NHHNPPIF_00748 5.5e-24 L DNA packaging
NHHNPPIF_00749 1.1e-31
NHHNPPIF_00752 3.1e-24 S YopX protein
NHHNPPIF_00754 2.2e-30 S sequence-specific DNA binding
NHHNPPIF_00755 2e-30 S Protein of unknown function (DUF1642)
NHHNPPIF_00757 2.7e-31 S Protein of unknown function (DUF1642)
NHHNPPIF_00760 3.9e-10
NHHNPPIF_00762 3.9e-78 S magnesium ion binding
NHHNPPIF_00763 6.6e-65 S Single-strand binding protein family
NHHNPPIF_00764 8e-49 S Protein of unknown function (DUF1351)
NHHNPPIF_00765 1.1e-33 S ERF superfamily
NHHNPPIF_00767 7.3e-133 S IstB-like ATP binding protein
NHHNPPIF_00768 2.1e-85 L N-terminal phage replisome organiser (Phage_rep_org_N)
NHHNPPIF_00772 2.3e-25
NHHNPPIF_00773 1.8e-08 S ORF6C domain
NHHNPPIF_00774 1.1e-137
NHHNPPIF_00775 2.4e-28 S sequence-specific DNA binding
NHHNPPIF_00776 7.5e-53 S sequence-specific DNA binding
NHHNPPIF_00777 2.3e-20 E Zn peptidase
NHHNPPIF_00778 1.7e-22 S Host cell surface-exposed lipoprotein
NHHNPPIF_00779 2.5e-206 S Phage integrase family
NHHNPPIF_00780 8.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHHNPPIF_00781 5.7e-77 yueI S Protein of unknown function (DUF1694)
NHHNPPIF_00782 2.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NHHNPPIF_00783 5.9e-45 yyaQ V Protein conserved in bacteria
NHHNPPIF_00784 5.2e-27 yyaQ S YjbR
NHHNPPIF_00785 9.9e-183 ccpA K Catabolite control protein A
NHHNPPIF_00786 3.5e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NHHNPPIF_00787 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NHHNPPIF_00788 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHHNPPIF_00789 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHHNPPIF_00790 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHHNPPIF_00791 2.6e-33 secG U Preprotein translocase subunit SecG
NHHNPPIF_00792 9.4e-220 mdtG EGP Major facilitator Superfamily
NHHNPPIF_00793 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHHNPPIF_00794 1.2e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHHNPPIF_00795 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHHNPPIF_00796 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NHHNPPIF_00797 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHHNPPIF_00798 1.8e-64 licT K antiterminator
NHHNPPIF_00799 1.1e-43 licT K transcriptional antiterminator
NHHNPPIF_00800 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHHNPPIF_00801 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NHHNPPIF_00802 3.9e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHHNPPIF_00803 4.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHHNPPIF_00804 1.5e-23 I Alpha/beta hydrolase family
NHHNPPIF_00805 1.9e-33 yugF I carboxylic ester hydrolase activity
NHHNPPIF_00806 1.5e-07
NHHNPPIF_00807 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NHHNPPIF_00808 1.2e-77 feoA P FeoA domain protein
NHHNPPIF_00809 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
NHHNPPIF_00810 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NHHNPPIF_00811 1.3e-34 ykuJ S protein conserved in bacteria
NHHNPPIF_00812 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHHNPPIF_00813 0.0 clpE O Belongs to the ClpA ClpB family
NHHNPPIF_00814 5.7e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NHHNPPIF_00815 2.4e-47 XK27_09445 S Domain of unknown function (DUF1827)
NHHNPPIF_00816 1.7e-07 yvaA 1.1.1.371 S inositol 2-dehydrogenase activity
NHHNPPIF_00817 1.4e-41 S oxidoreductase
NHHNPPIF_00818 3e-51 S oxidoreductase
NHHNPPIF_00819 9.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
NHHNPPIF_00820 2.9e-63 M Pfam SNARE associated Golgi protein
NHHNPPIF_00821 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
NHHNPPIF_00824 1.3e-202 rpsA 1.17.7.4 J ribosomal protein S1
NHHNPPIF_00827 1.1e-15 S Protein of unknown function (DUF2969)
NHHNPPIF_00828 3.4e-199 ilvE 2.6.1.42 E Aminotransferase
NHHNPPIF_00829 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHHNPPIF_00830 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHHNPPIF_00831 1.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHHNPPIF_00832 8.3e-15 L Helix-hairpin-helix DNA-binding motif class 1
NHHNPPIF_00833 1.4e-29 S Domain of unknown function (DUF1912)
NHHNPPIF_00834 3.4e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NHHNPPIF_00835 9.2e-248 mmuP E amino acid
NHHNPPIF_00836 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NHHNPPIF_00837 3.7e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHHNPPIF_00838 9.7e-22
NHHNPPIF_00839 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHHNPPIF_00840 1.9e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHHNPPIF_00841 5e-218 mvaS 2.3.3.10 I synthase
NHHNPPIF_00842 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NHHNPPIF_00843 1e-25 K hmm pf08876
NHHNPPIF_00844 1.5e-118 yqfA K protein, Hemolysin III
NHHNPPIF_00845 4.6e-22 S Protein of unknown function (DUF3114)
NHHNPPIF_00846 4e-164 S Protein of unknown function (DUF3114)
NHHNPPIF_00847 3.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHHNPPIF_00848 7.1e-48 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHHNPPIF_00849 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHHNPPIF_00850 3.5e-49 XK27_13030
NHHNPPIF_00851 3.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NHHNPPIF_00852 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NHHNPPIF_00853 2.5e-08 M Pilin isopeptide linkage domain protein
NHHNPPIF_00854 1.8e-49 U protein secretion
NHHNPPIF_00855 3e-29 U protein secretion
NHHNPPIF_00857 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHHNPPIF_00858 2.5e-21
NHHNPPIF_00859 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NHHNPPIF_00860 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHHNPPIF_00861 6.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHHNPPIF_00862 3.1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
NHHNPPIF_00863 1.1e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NHHNPPIF_00864 4.6e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NHHNPPIF_00865 8.8e-104 GBS0088 J protein conserved in bacteria
NHHNPPIF_00866 1.3e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHHNPPIF_00867 9.1e-48 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NHHNPPIF_00868 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
NHHNPPIF_00869 5.7e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHHNPPIF_00870 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHHNPPIF_00871 5.6e-113 S VIT family
NHHNPPIF_00872 5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
NHHNPPIF_00873 2.9e-17
NHHNPPIF_00874 1.2e-26 XK27_00085 K Transcriptional
NHHNPPIF_00875 3.4e-196 yceA S Belongs to the UPF0176 family
NHHNPPIF_00876 5.4e-122 sagI S ABC-2 type transporter
NHHNPPIF_00877 4.8e-168 V ABC transporter
NHHNPPIF_00878 1.1e-178 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHHNPPIF_00879 6.3e-27 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHHNPPIF_00880 2.1e-131 rr02 KT response regulator
NHHNPPIF_00881 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NHHNPPIF_00882 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHHNPPIF_00883 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHHNPPIF_00884 0.0 lmrA V abc transporter atp-binding protein
NHHNPPIF_00885 0.0 mdlB V abc transporter atp-binding protein
NHHNPPIF_00887 0.0 M the current gene model (or a revised gene model) may contain a
NHHNPPIF_00888 6.5e-50 M YSIRK type signal peptide
NHHNPPIF_00889 3e-92 S MucBP domain
NHHNPPIF_00891 2.8e-164 hrtB V MacB-like periplasmic core domain
NHHNPPIF_00892 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
NHHNPPIF_00893 1.6e-18 L Integrase core domain
NHHNPPIF_00894 9.1e-229 L Transposase
NHHNPPIF_00895 8.9e-239 L Belongs to the 'phage' integrase family
NHHNPPIF_00896 1.2e-28 S Domain of unknown function (DUF3173)
NHHNPPIF_00897 6.1e-32 K transcriptional
NHHNPPIF_00898 8.8e-72 S ABC-2 family transporter protein
NHHNPPIF_00899 9.7e-82 S ABC-2 family transporter protein
NHHNPPIF_00900 7.2e-116 bcrA V abc transporter atp-binding protein
NHHNPPIF_00901 6.4e-205 V Lantibiotic transport processing ATP-binding protein
NHHNPPIF_00903 6.8e-93 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_00904 6.5e-169 T PhoQ Sensor
NHHNPPIF_00905 2.3e-214 U relaxase
NHHNPPIF_00906 7.9e-73 U relaxase
NHHNPPIF_00907 2.6e-56 S Bacterial mobilisation protein (MobC)
NHHNPPIF_00908 1.1e-54
NHHNPPIF_00909 1.6e-34
NHHNPPIF_00910 3e-90 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NHHNPPIF_00911 8.1e-108 abiGI K Transcriptional regulator, AbiEi antitoxin
NHHNPPIF_00912 0.0 M CHAP domain protein
NHHNPPIF_00913 1.5e-43 M CHAP domain protein
NHHNPPIF_00914 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
NHHNPPIF_00915 4.4e-53 XK27_00550 S PrgI family protein
NHHNPPIF_00916 3.3e-139 XK27_00555
NHHNPPIF_00917 3.2e-34 XK27_00560
NHHNPPIF_00918 0.0 traG U COG3505 Type IV secretory pathway, VirD4 components
NHHNPPIF_00919 1.1e-78
NHHNPPIF_00920 3.9e-91 3.4.11.19 V CAAX protease self-immunity
NHHNPPIF_00921 3.8e-37
NHHNPPIF_00922 1.9e-49
NHHNPPIF_00923 1.6e-73 XK27_00590
NHHNPPIF_00924 7.9e-260 hpaIIM 2.1.1.37 H cytosine-specific methyltransferase
NHHNPPIF_00925 4.8e-10
NHHNPPIF_00926 4.5e-133 repA S Replication initiator protein A (RepA) N-terminus
NHHNPPIF_00927 2.1e-19
NHHNPPIF_00928 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHHNPPIF_00929 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHHNPPIF_00930 8.2e-28 ytrF V efflux transmembrane transporter activity
NHHNPPIF_00931 3.1e-31 V efflux transmembrane transporter activity
NHHNPPIF_00932 3.6e-35 V efflux transmembrane transporter activity
NHHNPPIF_00933 2.1e-129 2.1.1.223 S Putative SAM-dependent methyltransferase
NHHNPPIF_00934 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NHHNPPIF_00935 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NHHNPPIF_00936 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NHHNPPIF_00937 4.9e-227 pyrP F uracil Permease
NHHNPPIF_00938 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHHNPPIF_00939 5.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHHNPPIF_00940 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHHNPPIF_00941 1.5e-166 fhuR K transcriptional regulator (lysR family)
NHHNPPIF_00946 4.1e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHHNPPIF_00947 1.3e-181 pts33BCA G pts system
NHHNPPIF_00948 7.4e-25 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NHHNPPIF_00949 3.2e-09 uvrX 2.7.7.7 L impB/mucB/samB family
NHHNPPIF_00950 2e-250 cycA E permease
NHHNPPIF_00951 1.4e-151 glcU U Glucose uptake
NHHNPPIF_00952 2.3e-93 hsdM 2.1.1.72 V type I restriction-modification system
NHHNPPIF_00953 2.6e-55 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
NHHNPPIF_00954 8.9e-11
NHHNPPIF_00955 7.8e-59 S Protein of unknown function (DUF1722)
NHHNPPIF_00956 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
NHHNPPIF_00958 2.4e-33
NHHNPPIF_00959 1.7e-26 S CAAX protease self-immunity
NHHNPPIF_00960 1e-30 S CAAX protease self-immunity
NHHNPPIF_00961 1.9e-27 estA E GDSL-like Lipase/Acylhydrolase
NHHNPPIF_00962 6.2e-95
NHHNPPIF_00963 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NHHNPPIF_00964 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHHNPPIF_00965 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHHNPPIF_00966 6.7e-198 S CRISPR-associated protein Csn2 subfamily St
NHHNPPIF_00967 9.3e-147 ycgQ S TIGR03943 family
NHHNPPIF_00968 1.4e-156 XK27_03015 S permease
NHHNPPIF_00970 0.0 yhgF K Transcriptional accessory protein
NHHNPPIF_00971 1.9e-40 pspC KT PspC domain
NHHNPPIF_00972 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHHNPPIF_00973 1.5e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHHNPPIF_00975 1.2e-68 ytxH S General stress protein
NHHNPPIF_00977 1.7e-176 yegQ O Peptidase U32
NHHNPPIF_00978 3.4e-252 yegQ O Peptidase U32
NHHNPPIF_00979 2.7e-86 bioY S biotin synthase
NHHNPPIF_00981 1.1e-33 XK27_12190 S protein conserved in bacteria
NHHNPPIF_00982 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
NHHNPPIF_00984 1.5e-101 yiiE S protein homotetramerization
NHHNPPIF_00991 4.5e-39 ynzC S UPF0291 protein
NHHNPPIF_00992 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NHHNPPIF_00993 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NHHNPPIF_00994 6.1e-63 S membrane
NHHNPPIF_00995 3.9e-60
NHHNPPIF_00996 2.2e-25
NHHNPPIF_00997 4.9e-51
NHHNPPIF_00998 8e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHHNPPIF_00999 1.2e-92 nptA P COG1283 Na phosphate symporter
NHHNPPIF_01000 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NHHNPPIF_01001 1.3e-103 mur1 NU mannosyl-glycoprotein
NHHNPPIF_01002 1.2e-52 glnB K Belongs to the P(II) protein family
NHHNPPIF_01003 3.7e-232 amt P Ammonium Transporter
NHHNPPIF_01006 5.3e-11
NHHNPPIF_01019 1e-13 rpmH J Ribosomal protein L34
NHHNPPIF_01021 3.2e-184 jag S RNA-binding protein
NHHNPPIF_01022 8.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHHNPPIF_01023 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHHNPPIF_01024 1.2e-263 argH 4.3.2.1 E Argininosuccinate lyase
NHHNPPIF_01025 2.9e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHHNPPIF_01026 1.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHHNPPIF_01027 1.6e-62 amiA E transmembrane transport
NHHNPPIF_01028 1.5e-181 amiA E ABC transporter, substrate-binding protein, family 5
NHHNPPIF_01029 1.8e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHHNPPIF_01030 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHHNPPIF_01031 3.5e-50 S Protein of unknown function (DUF3397)
NHHNPPIF_01032 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NHHNPPIF_01033 9.1e-29 WQ51_05710 S Mitochondrial biogenesis AIM24
NHHNPPIF_01034 3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
NHHNPPIF_01035 1.4e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
NHHNPPIF_01036 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHHNPPIF_01037 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NHHNPPIF_01038 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
NHHNPPIF_01039 4.6e-35 XK27_09620 S FMN reductase (NADPH) activity
NHHNPPIF_01040 7.4e-220 XK27_09615 C reductase
NHHNPPIF_01041 2.1e-91 fnt P Formate nitrite transporter
NHHNPPIF_01042 3.5e-32 XK27_08585 S Psort location CytoplasmicMembrane, score
NHHNPPIF_01043 4.7e-29 XK27_08585 S Psort location CytoplasmicMembrane, score
NHHNPPIF_01044 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NHHNPPIF_01045 4.8e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHHNPPIF_01046 2.6e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NHHNPPIF_01047 1e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHHNPPIF_01048 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHHNPPIF_01049 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHHNPPIF_01050 7.8e-48 S glycolate biosynthetic process
NHHNPPIF_01051 1.7e-63 S phosphatase activity
NHHNPPIF_01052 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
NHHNPPIF_01055 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHHNPPIF_01056 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHHNPPIF_01057 6.4e-37 yeeD O sulfur carrier activity
NHHNPPIF_01058 2.8e-188 yeeE S Sulphur transport
NHHNPPIF_01059 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHHNPPIF_01060 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NHHNPPIF_01061 1.8e-09 S Domain of unknown function (DUF4651)
NHHNPPIF_01062 7.5e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NHHNPPIF_01063 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHHNPPIF_01064 2.1e-109 S CAAX amino terminal protease family protein
NHHNPPIF_01066 1.4e-66 V CAAX protease self-immunity
NHHNPPIF_01067 2.6e-26 lanR K sequence-specific DNA binding
NHHNPPIF_01068 3.2e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHHNPPIF_01069 4.2e-175 ytxK 2.1.1.72 L DNA methylase
NHHNPPIF_01070 2.2e-11 comGF U Putative Competence protein ComGF
NHHNPPIF_01071 1.3e-70 comGF U Competence protein ComGF
NHHNPPIF_01072 4.1e-15 NU Type II secretory pathway pseudopilin
NHHNPPIF_01073 2.6e-56 cglD NU Competence protein
NHHNPPIF_01074 2.5e-42 comGC U Required for transformation and DNA binding
NHHNPPIF_01075 4.5e-152 cglB NU type II secretion system
NHHNPPIF_01076 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHHNPPIF_01077 2.7e-66 S cog cog4699
NHHNPPIF_01078 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHHNPPIF_01079 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHHNPPIF_01080 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHHNPPIF_01081 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHHNPPIF_01082 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHHNPPIF_01083 1.1e-75 ilvN 2.2.1.6 E Acetolactate synthase
NHHNPPIF_01084 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NHHNPPIF_01085 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NHHNPPIF_01086 6.7e-301 yloV S kinase related to dihydroxyacetone kinase
NHHNPPIF_01087 1.8e-57 asp S cog cog1302
NHHNPPIF_01088 2.7e-225 norN V Mate efflux family protein
NHHNPPIF_01089 1.9e-278 thrC 4.2.3.1 E Threonine synthase
NHHNPPIF_01090 2.6e-39 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NHHNPPIF_01091 2.3e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NHHNPPIF_01092 1.9e-156 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NHHNPPIF_01093 1.8e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
NHHNPPIF_01094 0.0 pepO 3.4.24.71 O Peptidase family M13
NHHNPPIF_01095 1.4e-114 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NHHNPPIF_01096 5.5e-80 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NHHNPPIF_01097 1.4e-54 treB 2.7.1.201 G PTS System
NHHNPPIF_01098 8.6e-87 treR K trehalose operon
NHHNPPIF_01099 2.2e-94 ywlG S Belongs to the UPF0340 family
NHHNPPIF_01102 3.2e-33 L PFAM Integrase, catalytic core
NHHNPPIF_01103 9.3e-72 L PFAM Integrase, catalytic core
NHHNPPIF_01104 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
NHHNPPIF_01105 2.8e-13 L thioesterase
NHHNPPIF_01106 7.8e-143 S Macro domain protein
NHHNPPIF_01107 1.1e-50 trxA O Belongs to the thioredoxin family
NHHNPPIF_01108 1.9e-74 yccU S CoA-binding protein
NHHNPPIF_01109 4.1e-144 tatD L Hydrolase, tatd
NHHNPPIF_01110 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHHNPPIF_01111 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHHNPPIF_01113 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHHNPPIF_01114 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NHHNPPIF_01115 9.2e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
NHHNPPIF_01116 4.5e-172 rmuC S RmuC domain protein
NHHNPPIF_01117 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
NHHNPPIF_01118 7e-142 purR 2.4.2.7 F operon repressor
NHHNPPIF_01119 5.1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHHNPPIF_01120 4.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHHNPPIF_01121 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHHNPPIF_01122 9.3e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHHNPPIF_01123 4.1e-158 L COG2801 Transposase and inactivated derivatives
NHHNPPIF_01124 1.6e-44 L Transposase
NHHNPPIF_01125 1.7e-48 adk 2.7.4.3 F topology modulation protein
NHHNPPIF_01126 1.7e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHHNPPIF_01127 9.7e-30 S Domain of unknown function (DUF4649)
NHHNPPIF_01128 3.9e-127 Z012_04635 K sequence-specific DNA binding
NHHNPPIF_01130 3.6e-232 C Radical SAM
NHHNPPIF_01131 5.6e-286 V ABC transporter transmembrane region
NHHNPPIF_01132 2.5e-89 K sequence-specific DNA binding
NHHNPPIF_01133 2.9e-155 L Replication initiation factor
NHHNPPIF_01134 1.9e-18 S Domain of unknown function (DUF3173)
NHHNPPIF_01135 7.7e-216 int L Belongs to the 'phage' integrase family
NHHNPPIF_01137 1.1e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NHHNPPIF_01138 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NHHNPPIF_01139 1.4e-43 yrzL S Belongs to the UPF0297 family
NHHNPPIF_01140 6.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHHNPPIF_01141 4.2e-44 yrzB S Belongs to the UPF0473 family
NHHNPPIF_01142 2.6e-297 ccs S the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_01143 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NHHNPPIF_01144 7.5e-14
NHHNPPIF_01145 2.6e-91 XK27_10930 K acetyltransferase
NHHNPPIF_01146 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHHNPPIF_01147 2.4e-147 yaaA S Belongs to the UPF0246 family
NHHNPPIF_01148 9.9e-169 XK27_01785 S cog cog1284
NHHNPPIF_01149 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHHNPPIF_01151 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
NHHNPPIF_01152 5.7e-52 metE 2.1.1.14 E Methionine synthase
NHHNPPIF_01153 7.6e-64 metE 2.1.1.14 E Methionine synthase
NHHNPPIF_01154 9.2e-36 metE 2.1.1.14 E Methionine synthase
NHHNPPIF_01155 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NHHNPPIF_01156 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHHNPPIF_01159 3.9e-115 yegS 2.7.1.107 I Diacylglycerol kinase
NHHNPPIF_01160 2.9e-15 yegS 2.7.1.107 I Diacylglycerol kinase
NHHNPPIF_01161 3.6e-95 S Hydrophobic domain protein
NHHNPPIF_01163 1.5e-10 XK27_01265 S ECF-type riboflavin transporter, S component
NHHNPPIF_01164 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NHHNPPIF_01165 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NHHNPPIF_01166 2e-86 S ECF-type riboflavin transporter, S component
NHHNPPIF_01168 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHHNPPIF_01169 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NHHNPPIF_01171 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHHNPPIF_01172 3.8e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHHNPPIF_01173 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHHNPPIF_01174 0.0 smc D Required for chromosome condensation and partitioning
NHHNPPIF_01175 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHHNPPIF_01176 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHHNPPIF_01177 3.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHHNPPIF_01178 1.7e-78 alkD L Dna alkylation repair
NHHNPPIF_01179 2.8e-93 pat 2.3.1.183 M acetyltransferase
NHHNPPIF_01180 1.6e-11 L Transposase
NHHNPPIF_01183 5.6e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHHNPPIF_01184 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NHHNPPIF_01185 5.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHHNPPIF_01186 1.7e-204 yurR 1.4.5.1 E oxidoreductase
NHHNPPIF_01187 1.6e-101 zupT P Mediates zinc uptake. May also transport other divalent cations
NHHNPPIF_01188 7e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
NHHNPPIF_01189 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHHNPPIF_01190 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NHHNPPIF_01191 1.3e-70 gtrA S GtrA-like protein
NHHNPPIF_01192 8.2e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHHNPPIF_01193 4.3e-167 ybbR S Protein conserved in bacteria
NHHNPPIF_01194 2.8e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHHNPPIF_01195 1.8e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NHHNPPIF_01196 3.3e-149 cobQ S glutamine amidotransferase
NHHNPPIF_01197 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHHNPPIF_01198 3.1e-130 pip 1.11.1.10 S Alpha beta hydrolase
NHHNPPIF_01200 0.0 uup S abc transporter atp-binding protein
NHHNPPIF_01201 6.2e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NHHNPPIF_01202 1.5e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
NHHNPPIF_01203 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NHHNPPIF_01204 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NHHNPPIF_01205 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHHNPPIF_01206 7.9e-39 ptsH G phosphocarrier protein Hpr
NHHNPPIF_01207 8.2e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
NHHNPPIF_01208 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
NHHNPPIF_01209 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHHNPPIF_01210 8.5e-34 nrdH O Glutaredoxin
NHHNPPIF_01211 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHHNPPIF_01212 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHHNPPIF_01214 4.2e-71 L Transposase (IS116 IS110 IS902 family)
NHHNPPIF_01215 8.8e-60 L Transposase (IS116 IS110 IS902 family)
NHHNPPIF_01216 5.3e-165 ypuA S secreted protein
NHHNPPIF_01217 1.5e-52 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
NHHNPPIF_01218 1.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NHHNPPIF_01219 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHHNPPIF_01220 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHHNPPIF_01221 8.3e-257 noxE P NADH oxidase
NHHNPPIF_01222 3.6e-293 yfmM S abc transporter atp-binding protein
NHHNPPIF_01223 4.8e-59 XK27_01265 S ECF-type riboflavin transporter, S component
NHHNPPIF_01224 1.5e-37 L transposase activity
NHHNPPIF_01225 0.0 M family 8
NHHNPPIF_01226 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
NHHNPPIF_01227 1.1e-74 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
NHHNPPIF_01228 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NHHNPPIF_01230 9.4e-11
NHHNPPIF_01231 8.5e-117
NHHNPPIF_01232 4.2e-264 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01233 3.2e-59
NHHNPPIF_01235 2.7e-71 S Signal peptide protein, YSIRK family
NHHNPPIF_01236 4.8e-55 K response regulator
NHHNPPIF_01238 3e-284 XK27_07020 S Belongs to the UPF0371 family
NHHNPPIF_01239 2.6e-180 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHHNPPIF_01240 8.4e-159 yvgN C reductase
NHHNPPIF_01241 8.1e-27 yoaK S Protein of unknown function (DUF1275)
NHHNPPIF_01242 8.2e-68 yoaK S Protein of unknown function (DUF1275)
NHHNPPIF_01243 2.2e-111 drgA C Nitroreductase
NHHNPPIF_01244 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHHNPPIF_01245 1.6e-157 E Alpha/beta hydrolase of unknown function (DUF915)
NHHNPPIF_01246 4.7e-76 ywnA K Transcriptional regulator
NHHNPPIF_01247 1.6e-12
NHHNPPIF_01250 5.3e-16
NHHNPPIF_01251 2.2e-54 S TM2 domain
NHHNPPIF_01252 3.1e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHHNPPIF_01253 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHHNPPIF_01254 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHHNPPIF_01255 2.2e-24 secE U Belongs to the SecE SEC61-gamma family
NHHNPPIF_01256 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
NHHNPPIF_01257 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NHHNPPIF_01258 4e-47 cof Q phosphatase activity
NHHNPPIF_01259 2.1e-35 cof Q phosphatase activity
NHHNPPIF_01260 8.7e-99 glcR K transcriptional regulator (DeoR family)
NHHNPPIF_01261 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHHNPPIF_01263 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
NHHNPPIF_01264 8.3e-126 S COG1073 Hydrolases of the alpha beta superfamily
NHHNPPIF_01265 3.2e-275 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHHNPPIF_01266 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHHNPPIF_01267 3.2e-77 yhaI L Membrane
NHHNPPIF_01268 5.1e-259 pepC 3.4.22.40 E aminopeptidase
NHHNPPIF_01269 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHHNPPIF_01270 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHHNPPIF_01271 3.1e-95 ypsA S Belongs to the UPF0398 family
NHHNPPIF_01272 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHHNPPIF_01273 3.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NHHNPPIF_01274 4.7e-303 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NHHNPPIF_01275 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NHHNPPIF_01276 2.5e-23
NHHNPPIF_01277 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NHHNPPIF_01278 5.6e-52 XK27_09675 K -acetyltransferase
NHHNPPIF_01279 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHHNPPIF_01280 4.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHHNPPIF_01281 2.6e-88 L Integrase core domain protein
NHHNPPIF_01282 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHHNPPIF_01283 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NHHNPPIF_01284 1.9e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHHNPPIF_01285 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NHHNPPIF_01286 1.5e-97 ybhL S Belongs to the BI1 family
NHHNPPIF_01289 1.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHHNPPIF_01290 2.4e-90 K transcriptional regulator
NHHNPPIF_01291 7.6e-36 yneF S UPF0154 protein
NHHNPPIF_01292 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NHHNPPIF_01293 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHHNPPIF_01294 3.5e-99 XK27_09740 S Phosphoesterase
NHHNPPIF_01295 7.8e-85 ykuL S CBS domain
NHHNPPIF_01296 2.8e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NHHNPPIF_01297 1.5e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHHNPPIF_01298 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHHNPPIF_01299 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHHNPPIF_01300 4e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NHHNPPIF_01301 4.8e-255 trkH P Cation transport protein
NHHNPPIF_01302 1.4e-245 trkA P Potassium transporter peripheral membrane component
NHHNPPIF_01303 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHHNPPIF_01304 5.5e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHHNPPIF_01305 1.1e-110 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NHHNPPIF_01306 1.2e-160 K sequence-specific DNA binding
NHHNPPIF_01307 1.9e-33 V protein secretion by the type I secretion system
NHHNPPIF_01308 5.5e-105 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_01309 3.2e-75 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_01310 2.4e-85 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_01311 2.1e-30 yhaI L Membrane
NHHNPPIF_01312 1.5e-56 S Domain of unknown function (DUF4173)
NHHNPPIF_01313 3.4e-94 ureI S AmiS/UreI family transporter
NHHNPPIF_01314 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NHHNPPIF_01315 1.7e-53 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NHHNPPIF_01316 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NHHNPPIF_01317 6.6e-78 ureE O enzyme active site formation
NHHNPPIF_01318 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHHNPPIF_01319 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NHHNPPIF_01320 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHHNPPIF_01321 3.9e-176 cbiM P PDGLE domain
NHHNPPIF_01322 2.3e-134 P cobalt transport protein
NHHNPPIF_01323 3.1e-130 cbiO P ABC transporter
NHHNPPIF_01324 8.2e-274 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NHHNPPIF_01325 2.1e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHHNPPIF_01326 0.0 dnaE 2.7.7.7 L DNA polymerase
NHHNPPIF_01327 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
NHHNPPIF_01328 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHHNPPIF_01329 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHHNPPIF_01330 2.5e-43 ysdA L Membrane
NHHNPPIF_01331 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHHNPPIF_01332 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHHNPPIF_01333 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHHNPPIF_01334 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NHHNPPIF_01336 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHHNPPIF_01337 1.7e-94 ypmS S Protein conserved in bacteria
NHHNPPIF_01338 6.7e-87 ypmR E lipolytic protein G-D-S-L family
NHHNPPIF_01339 3.8e-45 ypmR E COG2755 Lysophospholipase L1 and related esterases
NHHNPPIF_01340 3.3e-147 DegV S DegV family
NHHNPPIF_01341 2.9e-304 recN L May be involved in recombinational repair of damaged DNA
NHHNPPIF_01342 3.7e-73 argR K Regulates arginine biosynthesis genes
NHHNPPIF_01343 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NHHNPPIF_01344 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHHNPPIF_01345 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
NHHNPPIF_01346 2.6e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHHNPPIF_01347 2.5e-07 KT response to antibiotic
NHHNPPIF_01349 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHHNPPIF_01350 1.5e-124 dnaD
NHHNPPIF_01351 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHHNPPIF_01352 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHHNPPIF_01353 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NHHNPPIF_01354 1.5e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHHNPPIF_01355 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHHNPPIF_01356 3.9e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NHHNPPIF_01357 2.7e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHHNPPIF_01358 7.3e-232 rodA D Belongs to the SEDS family
NHHNPPIF_01359 2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NHHNPPIF_01360 8e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHHNPPIF_01361 8.9e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHHNPPIF_01362 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHHNPPIF_01363 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHHNPPIF_01364 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NHHNPPIF_01365 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHHNPPIF_01366 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHHNPPIF_01367 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHHNPPIF_01368 8.2e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHHNPPIF_01370 1.3e-31 L Integrase core domain protein
NHHNPPIF_01371 1e-69 doc S Prophage maintenance system killer protein
NHHNPPIF_01372 3.3e-30 S Antidote-toxin recognition MazE, bacterial antitoxin
NHHNPPIF_01373 8.5e-09
NHHNPPIF_01374 3.1e-44 L COG2963 Transposase and inactivated derivatives
NHHNPPIF_01375 5.9e-62 L Transposase and inactivated derivatives
NHHNPPIF_01376 1.5e-39 L transposition
NHHNPPIF_01377 4.2e-92 dps P Belongs to the Dps family
NHHNPPIF_01378 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NHHNPPIF_01379 6.3e-191 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NHHNPPIF_01387 9.5e-140 blpT
NHHNPPIF_01388 3e-47 spiA K sequence-specific DNA binding
NHHNPPIF_01391 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHHNPPIF_01392 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NHHNPPIF_01393 1.3e-196 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
NHHNPPIF_01394 2.2e-186 yxaM EGP Major facilitator Superfamily
NHHNPPIF_01395 1.1e-89 adk 2.7.4.3 F topology modulation protein
NHHNPPIF_01396 7.8e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHHNPPIF_01397 2.9e-24 L Transposase
NHHNPPIF_01398 1.2e-24 oppF P Belongs to the ABC transporter superfamily
NHHNPPIF_01399 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NHHNPPIF_01400 1.1e-270 amiC P ABC transporter (Permease
NHHNPPIF_01401 3.1e-167 amiD P ABC transporter (Permease
NHHNPPIF_01402 1.4e-203 oppD P Belongs to the ABC transporter superfamily
NHHNPPIF_01403 5.2e-119 oppF P Belongs to the ABC transporter superfamily
NHHNPPIF_01404 1.7e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NHHNPPIF_01405 7.9e-41 L COG1943 Transposase and inactivated derivatives
NHHNPPIF_01406 5.3e-150 1.13.11.2 S glyoxalase
NHHNPPIF_01407 5.7e-109 XK27_02070 S nitroreductase
NHHNPPIF_01409 2.1e-71 ydhF S Aldo keto reductase
NHHNPPIF_01410 9.4e-68 ydhF S Aldo keto reductase
NHHNPPIF_01411 3.9e-82 K WHG domain
NHHNPPIF_01412 3.2e-91 V abc transporter atp-binding protein
NHHNPPIF_01413 5.9e-23 P FtsX-like permease family
NHHNPPIF_01414 2.4e-40 S Sugar efflux transporter for intercellular exchange
NHHNPPIF_01415 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NHHNPPIF_01416 4e-160 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
NHHNPPIF_01417 2.4e-161 ET ABC transporter substrate-binding protein
NHHNPPIF_01418 6.1e-107 ytmL P ABC transporter (Permease
NHHNPPIF_01419 6.7e-114 yxeN P ABC transporter, permease protein
NHHNPPIF_01420 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
NHHNPPIF_01423 1.6e-21 L Integrase core domain protein
NHHNPPIF_01424 1.1e-139 S dextransucrase activity
NHHNPPIF_01425 8.8e-39 S dextransucrase activity
NHHNPPIF_01426 6.3e-14 S dextransucrase activity
NHHNPPIF_01427 4e-69 S dextransucrase activity
NHHNPPIF_01428 1.1e-227 yfnA E amino acid
NHHNPPIF_01430 4.8e-25 csbD K CsbD-like
NHHNPPIF_01431 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHHNPPIF_01432 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHHNPPIF_01433 1.5e-234 brnQ E Component of the transport system for branched-chain amino acids
NHHNPPIF_01434 2.3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHHNPPIF_01435 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
NHHNPPIF_01436 5.7e-102 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
NHHNPPIF_01437 6e-147 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NHHNPPIF_01438 2.3e-115 yxeQ S MmgE/PrpD family
NHHNPPIF_01439 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
NHHNPPIF_01440 1.4e-63 yxeN U ABC transporter, permease protein
NHHNPPIF_01441 2.8e-92 yxeO 3.6.3.21 E abc transporter atp-binding protein
NHHNPPIF_01442 1.1e-197 pcaB 4.3.2.2 F Adenylosuccinate lyase
NHHNPPIF_01443 2.6e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_01444 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHHNPPIF_01445 4.5e-247 norM V Multidrug efflux pump
NHHNPPIF_01446 4.4e-59 pbuX F xanthine permease
NHHNPPIF_01447 8.4e-141 pbuX F xanthine permease
NHHNPPIF_01448 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHHNPPIF_01449 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_01450 3.1e-165 T Histidine kinase
NHHNPPIF_01451 2.4e-133 macB2 V ABC transporter, ATP-binding protein
NHHNPPIF_01452 0.0 V ABC transporter (permease)
NHHNPPIF_01453 2.6e-35 XK27_05000 S metal cluster binding
NHHNPPIF_01454 1.4e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
NHHNPPIF_01455 2.5e-164 yocS S Transporter
NHHNPPIF_01458 2.2e-157 XK27_09825 V abc transporter atp-binding protein
NHHNPPIF_01459 1.1e-130 yvfS V ABC-2 type transporter
NHHNPPIF_01460 4.5e-189 desK 2.7.13.3 T Histidine kinase
NHHNPPIF_01461 1.3e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHHNPPIF_01462 4.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
NHHNPPIF_01463 2.5e-308 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NHHNPPIF_01464 1.6e-205 S Protein of unknown function (DUF917)
NHHNPPIF_01465 2.5e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
NHHNPPIF_01466 4.3e-102 proWZ P ABC transporter (Permease
NHHNPPIF_01467 3.8e-165 proX M ABC transporter, substrate-binding protein, QAT family
NHHNPPIF_01468 1.6e-137 proV E abc transporter atp-binding protein
NHHNPPIF_01469 4.4e-88 proW P Binding-protein-dependent transport system inner membrane component
NHHNPPIF_01470 1.5e-21 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NHHNPPIF_01471 3.9e-37 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NHHNPPIF_01472 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHHNPPIF_01473 6.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHHNPPIF_01474 1e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
NHHNPPIF_01475 1.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NHHNPPIF_01476 2.8e-230 ytoI K transcriptional regulator containing CBS domains
NHHNPPIF_01477 7.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NHHNPPIF_01478 2.4e-159 rbn E Belongs to the UPF0761 family
NHHNPPIF_01479 1.3e-85 ccl S cog cog4708
NHHNPPIF_01480 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHHNPPIF_01481 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHHNPPIF_01482 1.7e-119 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
NHHNPPIF_01483 2.1e-74 S QueT transporter
NHHNPPIF_01484 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
NHHNPPIF_01485 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NHHNPPIF_01486 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NHHNPPIF_01487 4.1e-37 ylqC L Belongs to the UPF0109 family
NHHNPPIF_01488 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHHNPPIF_01489 0.0 ydaO E amino acid
NHHNPPIF_01490 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
NHHNPPIF_01491 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHHNPPIF_01492 3e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NHHNPPIF_01493 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHHNPPIF_01494 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHHNPPIF_01495 7.8e-171 murB 1.3.1.98 M cell wall formation
NHHNPPIF_01496 2.8e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHHNPPIF_01497 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
NHHNPPIF_01498 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
NHHNPPIF_01499 2.3e-206 potD P spermidine putrescine ABC transporter
NHHNPPIF_01500 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
NHHNPPIF_01501 1.7e-36 XK27_08050 O HflC and HflK could regulate a protease
NHHNPPIF_01502 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
NHHNPPIF_01503 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
NHHNPPIF_01504 4.1e-54 GK ROK family
NHHNPPIF_01505 4e-50 GK ROK family
NHHNPPIF_01506 1.9e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHHNPPIF_01507 1.3e-104 wecD M Acetyltransferase (GNAT) domain
NHHNPPIF_01508 1.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHHNPPIF_01509 5.3e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NHHNPPIF_01510 3.2e-59 arsC 1.20.4.1 P Belongs to the ArsC family
NHHNPPIF_01512 7.7e-56 lrgA S Effector of murein hydrolase LrgA
NHHNPPIF_01513 2.2e-117 lrgB M effector of murein hydrolase
NHHNPPIF_01514 1.6e-97 3.1.3.18 S IA, variant 1
NHHNPPIF_01515 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHHNPPIF_01516 6.2e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHHNPPIF_01517 4.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
NHHNPPIF_01518 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NHHNPPIF_01519 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHHNPPIF_01520 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHHNPPIF_01521 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
NHHNPPIF_01523 3.8e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
NHHNPPIF_01525 3.9e-50 ycaO O OsmC-like protein
NHHNPPIF_01526 1.6e-64 paaI Q protein possibly involved in aromatic compounds catabolism
NHHNPPIF_01529 6.4e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHHNPPIF_01530 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHHNPPIF_01531 1.1e-16 XK27_00735
NHHNPPIF_01532 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
NHHNPPIF_01533 1.3e-149 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NHHNPPIF_01534 1.8e-237 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NHHNPPIF_01535 2.4e-33 S CAAX amino terminal protease family protein
NHHNPPIF_01536 4.3e-82 S CAAX amino terminal protease family protein
NHHNPPIF_01538 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHHNPPIF_01539 2.9e-84 mutT 3.6.1.55 F Nudix family
NHHNPPIF_01540 1.7e-140 ET Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_01541 8.8e-134 ET ABC transporter
NHHNPPIF_01542 1.7e-199 arcT 2.6.1.1 E Aminotransferase
NHHNPPIF_01543 4.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
NHHNPPIF_01544 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NHHNPPIF_01545 1.5e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHHNPPIF_01546 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHHNPPIF_01547 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHHNPPIF_01548 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NHHNPPIF_01549 9.8e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NHHNPPIF_01550 1.9e-245
NHHNPPIF_01551 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHHNPPIF_01552 8.2e-219 amrA S membrane protein involved in the export of O-antigen and teichoic acid
NHHNPPIF_01553 6e-185 S Glycosyltransferase like family 2
NHHNPPIF_01554 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
NHHNPPIF_01555 6.9e-130 arnC M group 2 family protein
NHHNPPIF_01556 4.6e-42 S Uncharacterized conserved protein (DUF2304)
NHHNPPIF_01557 2.4e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
NHHNPPIF_01558 2.3e-228 rgpA GT4 M Domain of unknown function (DUF1972)
NHHNPPIF_01559 6.4e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
NHHNPPIF_01560 1.8e-142 rgpC GM Transport permease protein
NHHNPPIF_01561 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHHNPPIF_01562 4.5e-305 GT4 M transferase activity, transferring glycosyl groups
NHHNPPIF_01563 0.0 rgpF M Rhamnan synthesis protein F
NHHNPPIF_01564 1.7e-268 M Psort location CytoplasmicMembrane, score
NHHNPPIF_01565 1.2e-115 radC E Belongs to the UPF0758 family
NHHNPPIF_01566 2.7e-123 puuD T peptidase C26
NHHNPPIF_01567 4.7e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHHNPPIF_01568 1e-57 XK27_04120 S Putative amino acid metabolism
NHHNPPIF_01569 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
NHHNPPIF_01570 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHHNPPIF_01571 1.5e-103 yjbK S Adenylate cyclase
NHHNPPIF_01572 1.4e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NHHNPPIF_01573 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHHNPPIF_01574 1.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NHHNPPIF_01575 5.9e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NHHNPPIF_01576 6.1e-37 L Transposase
NHHNPPIF_01577 2.8e-137 cppA E CppA N-terminal
NHHNPPIF_01578 3.8e-184 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NHHNPPIF_01579 3.1e-31
NHHNPPIF_01580 3e-116 ybbL S abc transporter atp-binding protein
NHHNPPIF_01581 2.3e-123 ybbM S transport system, permease component
NHHNPPIF_01582 7.6e-118 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
NHHNPPIF_01583 4.8e-58 L Phage integrase family
NHHNPPIF_01584 1.2e-32 L DNA integration
NHHNPPIF_01585 1e-31 D nuclear chromosome segregation
NHHNPPIF_01586 3.9e-42 D nuclear chromosome segregation
NHHNPPIF_01587 1.6e-09 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
NHHNPPIF_01588 1e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHHNPPIF_01589 5.8e-39 cah 4.2.1.1 P carbonic anhydrase
NHHNPPIF_01590 7.2e-43 cah 4.2.1.1 P carbonic anhydrase
NHHNPPIF_01591 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NHHNPPIF_01592 8.8e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01594 4.8e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHHNPPIF_01595 2.3e-162 yxeN P ABC transporter (Permease
NHHNPPIF_01596 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
NHHNPPIF_01597 1.1e-09 S Protein of unknown function (DUF4059)
NHHNPPIF_01598 5.5e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHHNPPIF_01599 4.3e-92 rsmD 2.1.1.171 L Methyltransferase
NHHNPPIF_01600 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHHNPPIF_01601 7.8e-194 ylbL T Belongs to the peptidase S16 family
NHHNPPIF_01602 3.3e-180 yhcC S radical SAM protein
NHHNPPIF_01603 2e-97 ytqB 2.1.1.176 J (SAM)-dependent
NHHNPPIF_01605 0.0 yjcE P NhaP-type Na H and K H antiporters
NHHNPPIF_01606 3.9e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NHHNPPIF_01607 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NHHNPPIF_01608 2.7e-151 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHHNPPIF_01610 6.9e-75 XK27_03180 T universal stress protein
NHHNPPIF_01611 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NHHNPPIF_01612 2.8e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHHNPPIF_01613 9.8e-100 pncA Q isochorismatase
NHHNPPIF_01614 4.1e-122 hlpA M Belongs to the NlpA lipoprotein family
NHHNPPIF_01615 3.7e-60 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHHNPPIF_01616 1.5e-258 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHHNPPIF_01617 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHHNPPIF_01618 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHHNPPIF_01619 5.1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHHNPPIF_01620 2.1e-64
NHHNPPIF_01621 4.5e-80 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHHNPPIF_01622 4.7e-62 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHHNPPIF_01623 1.8e-98 yqeG S hydrolase of the HAD superfamily
NHHNPPIF_01624 7.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NHHNPPIF_01625 3.5e-49 yhbY J RNA-binding protein
NHHNPPIF_01626 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHHNPPIF_01627 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NHHNPPIF_01628 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHHNPPIF_01629 2e-140 yqeM Q Methyltransferase domain protein
NHHNPPIF_01630 1.9e-200 ylbM S Belongs to the UPF0348 family
NHHNPPIF_01631 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NHHNPPIF_01632 9.8e-19 S Membrane
NHHNPPIF_01633 1.7e-99
NHHNPPIF_01634 1.8e-23 S Small integral membrane protein
NHHNPPIF_01635 6.5e-83 M Protein conserved in bacteria
NHHNPPIF_01636 9.2e-11 K CsbD-like
NHHNPPIF_01637 6.7e-125 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHHNPPIF_01638 1.4e-135 HJ the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_01639 9.8e-19 S Membrane
NHHNPPIF_01640 1.7e-99
NHHNPPIF_01641 1.8e-23 S Small integral membrane protein
NHHNPPIF_01642 6.5e-83 M Protein conserved in bacteria
NHHNPPIF_01643 9.2e-11 K CsbD-like
NHHNPPIF_01644 1.1e-107 nudL L hydrolase
NHHNPPIF_01645 3.1e-44 L COG2963 Transposase and inactivated derivatives
NHHNPPIF_01646 5.9e-62 L Transposase and inactivated derivatives
NHHNPPIF_01647 1.5e-39 L transposition
NHHNPPIF_01648 2.2e-17
NHHNPPIF_01649 8.6e-41
NHHNPPIF_01650 1.8e-28 MU outer membrane autotransporter barrel domain protein
NHHNPPIF_01651 4.7e-62
NHHNPPIF_01652 2.6e-311 U Type IV secretory system Conjugative DNA transfer
NHHNPPIF_01653 8.6e-41
NHHNPPIF_01654 3e-29 MU outer membrane autotransporter barrel domain protein
NHHNPPIF_01655 4.7e-62
NHHNPPIF_01656 2.6e-311 U Type IV secretory system Conjugative DNA transfer
NHHNPPIF_01657 3.2e-66
NHHNPPIF_01659 1.1e-104
NHHNPPIF_01660 0.0 M CHAP domain protein
NHHNPPIF_01661 0.0 U Psort location Cytoplasmic, score
NHHNPPIF_01662 5e-12 S PrgI family protein
NHHNPPIF_01664 3e-104
NHHNPPIF_01666 4e-40 S Transcriptional Coactivator p15 (PC4)
NHHNPPIF_01667 1.7e-38
NHHNPPIF_01668 8.2e-96 repA S Replication initiator protein A (RepA) N-terminus
NHHNPPIF_01670 8.6e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NHHNPPIF_01671 7.1e-127 yrrM 2.1.1.104 S O-Methyltransferase
NHHNPPIF_01672 0.0 pepF E oligoendopeptidase F
NHHNPPIF_01673 1.4e-186 coiA 3.6.4.12 S Competence protein
NHHNPPIF_01674 3.5e-163 K transcriptional regulator (lysR family)
NHHNPPIF_01675 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHHNPPIF_01679 1e-190 phoH T phosphate starvation-inducible protein PhoH
NHHNPPIF_01680 1.7e-60 rlpA M LysM domain protein
NHHNPPIF_01681 4.1e-59 usp 3.5.1.28 CBM50 S CHAP domain
NHHNPPIF_01682 1.8e-153 ET amino acid transport
NHHNPPIF_01683 1.6e-27
NHHNPPIF_01684 0.0 ctpE P E1-E2 ATPase
NHHNPPIF_01685 2.7e-55
NHHNPPIF_01686 1.8e-41 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
NHHNPPIF_01687 2e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHHNPPIF_01688 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NHHNPPIF_01689 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHHNPPIF_01690 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NHHNPPIF_01691 5.5e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NHHNPPIF_01692 3.8e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHHNPPIF_01693 6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHHNPPIF_01694 2.7e-73 copY K Copper transport repressor, CopY TcrY family
NHHNPPIF_01695 0.0 copA 3.6.3.54 P P-type ATPase
NHHNPPIF_01696 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
NHHNPPIF_01697 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NHHNPPIF_01698 3.9e-114 papP P ABC transporter (Permease
NHHNPPIF_01699 3e-106 P ABC transporter (Permease
NHHNPPIF_01700 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
NHHNPPIF_01701 1.1e-155 cjaA ET ABC transporter substrate-binding protein
NHHNPPIF_01705 1.7e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHHNPPIF_01706 7.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
NHHNPPIF_01707 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHHNPPIF_01708 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHHNPPIF_01709 5.1e-47 L transposase activity
NHHNPPIF_01710 6e-121 K transcriptional regulator, MerR family
NHHNPPIF_01711 1.3e-102 dnaQ 2.7.7.7 L DNA polymerase III
NHHNPPIF_01712 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
NHHNPPIF_01713 4.8e-63 XK27_02560 S cog cog2151
NHHNPPIF_01714 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NHHNPPIF_01715 3.8e-226 ytfP S Flavoprotein
NHHNPPIF_01717 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHHNPPIF_01718 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
NHHNPPIF_01719 4.3e-181 ecsB U ABC transporter
NHHNPPIF_01720 1.1e-130 ecsA V abc transporter atp-binding protein
NHHNPPIF_01721 1.1e-69 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NHHNPPIF_01722 1.9e-09
NHHNPPIF_01724 1.1e-19
NHHNPPIF_01725 6.3e-07
NHHNPPIF_01726 4.5e-14
NHHNPPIF_01727 3.2e-33 L PFAM Integrase, catalytic core
NHHNPPIF_01728 9.3e-72 L PFAM Integrase, catalytic core
NHHNPPIF_01729 3.3e-62 rplQ J ribosomal protein l17
NHHNPPIF_01730 6.2e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHHNPPIF_01731 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHHNPPIF_01732 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHHNPPIF_01733 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NHHNPPIF_01734 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHHNPPIF_01735 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHHNPPIF_01736 3.6e-201 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHHNPPIF_01737 1.3e-57 rplO J binds to the 23S rRNA
NHHNPPIF_01738 2.5e-23 rpmD J ribosomal protein l30
NHHNPPIF_01739 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHHNPPIF_01740 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHHNPPIF_01741 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHHNPPIF_01742 1.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHHNPPIF_01743 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHHNPPIF_01744 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHHNPPIF_01745 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHHNPPIF_01746 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHHNPPIF_01747 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHHNPPIF_01748 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NHHNPPIF_01749 1e-69 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHHNPPIF_01750 7.5e-115 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHHNPPIF_01751 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHHNPPIF_01752 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHHNPPIF_01753 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHHNPPIF_01754 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHHNPPIF_01755 7.4e-104 rplD J Forms part of the polypeptide exit tunnel
NHHNPPIF_01756 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHHNPPIF_01757 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NHHNPPIF_01758 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHHNPPIF_01759 0.0 XK27_09800 I Acyltransferase
NHHNPPIF_01760 1.7e-35 XK27_09805 S MORN repeat protein
NHHNPPIF_01761 5.2e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHHNPPIF_01762 3.2e-33 L PFAM Integrase, catalytic core
NHHNPPIF_01763 9.3e-72 L PFAM Integrase, catalytic core
NHHNPPIF_01764 2.4e-199 L Belongs to the 'phage' integrase family
NHHNPPIF_01765 4.4e-29 S Psort location Cytoplasmic, score 8.87
NHHNPPIF_01766 4.1e-31 S Helix-turn-helix domain
NHHNPPIF_01767 2.6e-53 phyR K Sigma-70, region 4
NHHNPPIF_01768 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NHHNPPIF_01769 1.4e-63 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHHNPPIF_01770 1e-46 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
NHHNPPIF_01771 7.6e-154 L Integrase core domain protein
NHHNPPIF_01772 6.3e-38 L transposase activity
NHHNPPIF_01773 1.1e-199 EGP Major facilitator Superfamily
NHHNPPIF_01774 1.9e-32 spaC2 V Lanthionine synthetase C family protein
NHHNPPIF_01775 5.4e-197 L transposase, IS4 family
NHHNPPIF_01776 1.4e-15 tnp L DDE domain
NHHNPPIF_01777 2.1e-08 L Transposase
NHHNPPIF_01778 1.2e-43
NHHNPPIF_01779 1.6e-45
NHHNPPIF_01780 1.6e-206 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01781 9.3e-72 L PFAM Integrase, catalytic core
NHHNPPIF_01782 3.2e-33 L PFAM Integrase, catalytic core
NHHNPPIF_01783 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
NHHNPPIF_01784 7.3e-34 6.3.2.2 H gamma-glutamylcysteine synthetase
NHHNPPIF_01785 1.6e-103 6.3.2.2 H ergothioneine biosynthetic process
NHHNPPIF_01787 2.8e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
NHHNPPIF_01788 1.9e-13
NHHNPPIF_01789 2.7e-74 L PFAM Integrase catalytic region
NHHNPPIF_01790 9.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
NHHNPPIF_01791 1.4e-40 tatD L Hydrolase, tatd
NHHNPPIF_01792 1.1e-44 oppF P Belongs to the ABC transporter superfamily
NHHNPPIF_01793 1.5e-12
NHHNPPIF_01794 1.3e-87 S Fusaric acid resistance protein-like
NHHNPPIF_01795 8.5e-63 glnR K Transcriptional regulator
NHHNPPIF_01796 9.9e-263 glnA 6.3.1.2 E glutamine synthetase
NHHNPPIF_01798 3.2e-41 pscB M CHAP domain protein
NHHNPPIF_01799 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHHNPPIF_01800 2.5e-33 ykzG S Belongs to the UPF0356 family
NHHNPPIF_01801 2.1e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NHHNPPIF_01802 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHHNPPIF_01803 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHHNPPIF_01804 8.5e-117 azlC E AzlC protein
NHHNPPIF_01805 8.8e-48 azlD E branched-chain amino acid
NHHNPPIF_01806 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHHNPPIF_01807 1.9e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NHHNPPIF_01808 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHHNPPIF_01810 2.4e-103 repA S Replication initiator protein A (RepA) N-terminus
NHHNPPIF_01811 2.2e-46
NHHNPPIF_01812 1.4e-34 S Transcriptional Coactivator p15 (PC4)
NHHNPPIF_01814 9.6e-103
NHHNPPIF_01816 1.5e-13 S PrgI family protein
NHHNPPIF_01817 0.0 U Psort location Cytoplasmic, score
NHHNPPIF_01818 0.0 M CHAP domain protein
NHHNPPIF_01819 3.7e-64
NHHNPPIF_01821 1.4e-66
NHHNPPIF_01822 1.5e-12
NHHNPPIF_01823 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NHHNPPIF_01824 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHHNPPIF_01825 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NHHNPPIF_01826 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHHNPPIF_01827 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NHHNPPIF_01828 2.1e-114 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
NHHNPPIF_01829 7.4e-35 yozE S Belongs to the UPF0346 family
NHHNPPIF_01830 7e-161 cvfB S Protein conserved in bacteria
NHHNPPIF_01831 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHHNPPIF_01832 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NHHNPPIF_01833 4.5e-77 sptS 2.7.13.3 T Histidine kinase
NHHNPPIF_01834 1.4e-45 K Acetyltransferase (GNAT) family
NHHNPPIF_01835 0.0 lmrA2 V abc transporter atp-binding protein
NHHNPPIF_01836 0.0 lmrA1 V abc transporter atp-binding protein
NHHNPPIF_01837 7.2e-77 K DNA-binding transcription factor activity
NHHNPPIF_01838 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHHNPPIF_01839 6.9e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NHHNPPIF_01840 1.2e-163 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NHHNPPIF_01841 1e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NHHNPPIF_01842 3.3e-25 U response to pH
NHHNPPIF_01843 0.0 yfmR S abc transporter atp-binding protein
NHHNPPIF_01844 7.4e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHHNPPIF_01845 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHHNPPIF_01846 5.5e-75 XK27_08360 S EDD domain protein, DegV family
NHHNPPIF_01847 6.4e-61 XK27_08360 S EDD domain protein, DegV family
NHHNPPIF_01848 2.6e-64 WQ51_03320 S cog cog4835
NHHNPPIF_01849 6.7e-122 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHHNPPIF_01850 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NHHNPPIF_01851 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NHHNPPIF_01852 6.4e-29 2.3.1.128 K acetyltransferase
NHHNPPIF_01853 4.9e-39 2.3.1.128 K acetyltransferase
NHHNPPIF_01854 3e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NHHNPPIF_01855 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHHNPPIF_01856 1.2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHHNPPIF_01857 1.2e-208 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NHHNPPIF_01859 1.5e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHHNPPIF_01860 3e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHHNPPIF_01861 0.0 fruA 2.7.1.202 G phosphotransferase system
NHHNPPIF_01862 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NHHNPPIF_01863 1.2e-121 fruR K transcriptional
NHHNPPIF_01864 1.8e-84 L Transposase
NHHNPPIF_01865 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
NHHNPPIF_01866 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHHNPPIF_01867 1.5e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NHHNPPIF_01868 1.1e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHHNPPIF_01869 1.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NHHNPPIF_01870 4.3e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHHNPPIF_01871 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHHNPPIF_01872 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHHNPPIF_01873 1.6e-126 IQ reductase
NHHNPPIF_01874 1.9e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NHHNPPIF_01875 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NHHNPPIF_01876 2.6e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHHNPPIF_01877 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHHNPPIF_01878 2.3e-72 marR K Transcriptional regulator, MarR family
NHHNPPIF_01879 1e-137 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NHHNPPIF_01880 1.6e-114 S Haloacid dehalogenase-like hydrolase
NHHNPPIF_01881 5.9e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHHNPPIF_01882 6.7e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
NHHNPPIF_01883 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHHNPPIF_01884 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
NHHNPPIF_01885 7.8e-102 ygaC J Belongs to the UPF0374 family
NHHNPPIF_01886 4.1e-107 S Domain of unknown function (DUF1803)
NHHNPPIF_01887 2e-96 usp 3.5.1.28 CBM50 S CHAP domain
NHHNPPIF_01888 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NHHNPPIF_01889 3.6e-138 mreC M Involved in formation and maintenance of cell shape
NHHNPPIF_01893 4.2e-92 dps P Belongs to the Dps family
NHHNPPIF_01894 4.4e-79 perR P Belongs to the Fur family
NHHNPPIF_01895 1.9e-27 yqgQ S protein conserved in bacteria
NHHNPPIF_01896 7.8e-177 glk 2.7.1.2 G Glucokinase
NHHNPPIF_01897 0.0 typA T GTP-binding protein TypA
NHHNPPIF_01899 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHHNPPIF_01900 3.9e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHHNPPIF_01901 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHHNPPIF_01902 2.3e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHHNPPIF_01903 2.7e-236 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHHNPPIF_01904 5.1e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHHNPPIF_01905 1.4e-96 sepF D cell septum assembly
NHHNPPIF_01906 2e-34 yggT D integral membrane protein
NHHNPPIF_01907 8e-143 ylmH T S4 RNA-binding domain
NHHNPPIF_01908 3.3e-134 divIVA D Cell division protein DivIVA
NHHNPPIF_01909 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHHNPPIF_01910 7.9e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
NHHNPPIF_01911 2e-45 rpmE2 J 50S ribosomal protein L31
NHHNPPIF_01912 1e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHHNPPIF_01913 6.5e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NHHNPPIF_01914 2.6e-154 gst O Glutathione S-transferase
NHHNPPIF_01915 6.7e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHHNPPIF_01916 3.5e-111 tdk 2.7.1.21 F thymidine kinase
NHHNPPIF_01917 1.8e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHHNPPIF_01918 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHHNPPIF_01919 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHHNPPIF_01920 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHHNPPIF_01921 1e-176 ndpA S 37-kD nucleoid-associated bacterial protein
NHHNPPIF_01922 1.6e-106 pvaA M lytic transglycosylase activity
NHHNPPIF_01923 0.0 yfiB1 V abc transporter atp-binding protein
NHHNPPIF_01924 0.0 XK27_10035 V abc transporter atp-binding protein
NHHNPPIF_01925 1.2e-09 S D-Ala-teichoic acid biosynthesis protein
NHHNPPIF_01926 6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHHNPPIF_01927 1.6e-235 dltB M Membrane protein involved in D-alanine export
NHHNPPIF_01928 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHHNPPIF_01929 3.7e-227 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHHNPPIF_01930 1.4e-86 L Integrase core domain protein
NHHNPPIF_01931 7.1e-28 L transposase activity
NHHNPPIF_01933 6.4e-50
NHHNPPIF_01935 2.1e-120 S Protein of unknown function (DUF2786)
NHHNPPIF_01937 4.2e-278 repE K Primase C terminal 1 (PriCT-1)
NHHNPPIF_01939 6.1e-15
NHHNPPIF_01940 3.8e-40
NHHNPPIF_01941 4.6e-34 S Thioredoxin
NHHNPPIF_01942 1.2e-14
NHHNPPIF_01945 3.7e-89
NHHNPPIF_01948 3.6e-20 S the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_01949 1.7e-36 S the current gene model (or a revised gene model) may contain a frame shift
NHHNPPIF_01950 6.7e-142 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
NHHNPPIF_01951 1.6e-39
NHHNPPIF_01952 0.0 ruvB 3.6.4.12 L four-way junction helicase activity
NHHNPPIF_01953 7.5e-18
NHHNPPIF_01954 0.0 EL Toprim-like
NHHNPPIF_01956 0.0 topB 5.99.1.2 L Topoisomerase IA
NHHNPPIF_01957 0.0 clpB O Belongs to the ClpA ClpB family
NHHNPPIF_01958 2.9e-33
NHHNPPIF_01959 3.4e-197
NHHNPPIF_01960 1.8e-30 MU outer membrane autotransporter barrel domain protein
NHHNPPIF_01961 0.0 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NHHNPPIF_01962 1.2e-73 L single-stranded DNA binding
NHHNPPIF_01963 1.6e-189 nagZ 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NHHNPPIF_01965 1.9e-13
NHHNPPIF_01966 0.0 U COG3505 Type IV secretory pathway, VirD4 components
NHHNPPIF_01967 2.8e-26
NHHNPPIF_01968 1.4e-218
NHHNPPIF_01969 7.5e-27 S BRCA1 C Terminus (BRCT) domain
NHHNPPIF_01970 1.3e-13 S Uncharacterized protein pXO2-11
NHHNPPIF_01971 3e-84
NHHNPPIF_01972 0.0 trsE S COG0433 Predicted ATPase
NHHNPPIF_01973 1.7e-22
NHHNPPIF_01974 1.2e-231 NU amidase activity
NHHNPPIF_01975 2.9e-57
NHHNPPIF_01976 4e-150 D plasmid maintenance
NHHNPPIF_01977 4.6e-18
NHHNPPIF_01978 4e-28 S Replication initiator protein A (RepA) N-terminus
NHHNPPIF_01979 5e-09
NHHNPPIF_01980 3e-259 S Uncharacterised protein family (UPF0236)
NHHNPPIF_01981 2.4e-57 pepD E Dipeptidase
NHHNPPIF_01982 1.2e-86 XK27_10720 D peptidase activity
NHHNPPIF_01983 3.6e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
NHHNPPIF_01984 1.7e-08
NHHNPPIF_01985 1.5e-170 yeiH S Membrane
NHHNPPIF_01986 1.6e-118 mur1 NU muramidase
NHHNPPIF_01987 4.2e-20 L transposase activity
NHHNPPIF_01988 4.5e-166 cpsY K Transcriptional regulator
NHHNPPIF_01989 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHHNPPIF_01990 6.1e-57 phnA P Alkylphosphonate utilization operon protein PhnA
NHHNPPIF_01991 5.3e-105 artQ P ABC transporter (Permease
NHHNPPIF_01992 9.8e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
NHHNPPIF_01993 1.2e-157 aatB ET ABC transporter substrate-binding protein
NHHNPPIF_01994 2.1e-73 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01995 1.9e-110 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHHNPPIF_01996 2.1e-07
NHHNPPIF_01997 6.6e-62 adhP 1.1.1.1 C alcohol dehydrogenase
NHHNPPIF_01998 6.1e-112 adhP 1.1.1.1 C alcohol dehydrogenase
NHHNPPIF_02000 3e-21
NHHNPPIF_02001 0.0 res_1 3.1.21.5 S Type III restriction
NHHNPPIF_02002 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
NHHNPPIF_02003 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NHHNPPIF_02004 2e-126 gntR1 K transcriptional
NHHNPPIF_02005 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHHNPPIF_02006 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHHNPPIF_02007 3.1e-87 niaX
NHHNPPIF_02008 6e-91 niaR S small molecule binding protein (contains 3H domain)
NHHNPPIF_02009 8.1e-128 K DNA-binding helix-turn-helix protein
NHHNPPIF_02010 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHHNPPIF_02011 5.9e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHHNPPIF_02012 4e-85 GK ROK family
NHHNPPIF_02013 1.6e-70 GK ROK family
NHHNPPIF_02014 8.3e-159 dprA LU DNA protecting protein DprA
NHHNPPIF_02015 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHHNPPIF_02016 3.6e-154 S TraX protein
NHHNPPIF_02017 2.7e-120 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHHNPPIF_02018 1.9e-248 T PhoQ Sensor
NHHNPPIF_02019 9.6e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHHNPPIF_02020 6.5e-78 XK27_05470 E Methionine synthase
NHHNPPIF_02021 9.3e-36 XK27_05470 E Methionine synthase
NHHNPPIF_02022 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NHHNPPIF_02023 1.9e-46 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHHNPPIF_02024 6.8e-51 IQ Acetoin reductase
NHHNPPIF_02025 2.6e-45 IQ Acetoin reductase
NHHNPPIF_02027 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHHNPPIF_02031 1.1e-53 K peptidyl-tyrosine sulfation
NHHNPPIF_02032 1.6e-58 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NHHNPPIF_02033 2e-55 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NHHNPPIF_02036 1.1e-212 pqqE C radical SAM domain protein
NHHNPPIF_02037 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
NHHNPPIF_02038 6.6e-61 EGP Major facilitator Superfamily
NHHNPPIF_02039 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NHHNPPIF_02040 5.9e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NHHNPPIF_02041 6.2e-168 L Transposase
NHHNPPIF_02042 3e-48 K transcriptional regulator, PadR family
NHHNPPIF_02043 9.6e-08 XK27_06920 S Protein of unknown function (DUF1700)
NHHNPPIF_02044 9.1e-13 XK27_06920 S Protein of unknown function (DUF1700)
NHHNPPIF_02045 1.3e-106 S Putative adhesin
NHHNPPIF_02046 4e-158 XK27_06930 V domain protein
NHHNPPIF_02047 2.1e-94 XK27_06935 K transcriptional regulator
NHHNPPIF_02048 5.5e-11 ypaA M Membrane
NHHNPPIF_02049 2e-07
NHHNPPIF_02050 4.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHHNPPIF_02051 8.2e-48 veg S Biofilm formation stimulator VEG
NHHNPPIF_02052 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NHHNPPIF_02053 8.5e-73 rplI J binds to the 23S rRNA
NHHNPPIF_02054 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NHHNPPIF_02055 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHHNPPIF_02056 3.7e-76 F NUDIX domain
NHHNPPIF_02057 3.2e-214 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHHNPPIF_02058 1.2e-300 S Bacterial membrane protein, YfhO
NHHNPPIF_02059 1.7e-63 isaA GH23 M Immunodominant staphylococcal antigen A
NHHNPPIF_02060 3.9e-80 lytE M LysM domain protein
NHHNPPIF_02061 1.6e-135 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHHNPPIF_02062 2.6e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHHNPPIF_02063 6.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHHNPPIF_02064 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHHNPPIF_02065 7e-137 ymfM S sequence-specific DNA binding
NHHNPPIF_02066 4.7e-238 ymfH S Peptidase M16
NHHNPPIF_02067 4.5e-233 ymfF S Peptidase M16
NHHNPPIF_02068 3.6e-45 yaaA S S4 domain protein YaaA
NHHNPPIF_02069 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHHNPPIF_02070 4.7e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHHNPPIF_02071 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NHHNPPIF_02072 3.4e-124 yvjA S membrane
NHHNPPIF_02073 6.7e-306 ybiT S abc transporter atp-binding protein
NHHNPPIF_02074 0.0 XK27_10405 S Bacterial membrane protein YfhO
NHHNPPIF_02078 1.8e-119 yoaK S Psort location CytoplasmicMembrane, score
NHHNPPIF_02079 7.4e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHHNPPIF_02080 5.6e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NHHNPPIF_02081 1.4e-133 parB K Belongs to the ParB family
NHHNPPIF_02082 4.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHHNPPIF_02083 8.2e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHHNPPIF_02084 4.1e-29 yyzM S Protein conserved in bacteria
NHHNPPIF_02085 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHHNPPIF_02086 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHHNPPIF_02087 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHHNPPIF_02088 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NHHNPPIF_02089 2.7e-61 divIC D Septum formation initiator
NHHNPPIF_02091 1.5e-239 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NHHNPPIF_02092 1.2e-238 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHHNPPIF_02093 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NHHNPPIF_02094 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHHNPPIF_02095 1.7e-162 L Transposase
NHHNPPIF_02096 2.6e-10
NHHNPPIF_02099 1.9e-07
NHHNPPIF_02104 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHHNPPIF_02105 2.8e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NHHNPPIF_02106 1.6e-35 XK27_02060 S Transglycosylase associated protein
NHHNPPIF_02107 4.4e-55 badR K DNA-binding transcription factor activity
NHHNPPIF_02108 6e-97 S reductase
NHHNPPIF_02109 1.2e-32 L Integrase core domain protein
NHHNPPIF_02111 1.5e-172 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NHHNPPIF_02113 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NHHNPPIF_02114 3e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHHNPPIF_02115 9.3e-83 S Putative small multi-drug export protein
NHHNPPIF_02116 6.2e-76 ctsR K Belongs to the CtsR family
NHHNPPIF_02117 0.0 clpC O Belongs to the ClpA ClpB family
NHHNPPIF_02118 5.6e-129 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHHNPPIF_02119 3.9e-59 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHHNPPIF_02120 2.1e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHHNPPIF_02121 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHHNPPIF_02122 5e-142 S SseB protein N-terminal domain
NHHNPPIF_02123 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
NHHNPPIF_02124 6.6e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHHNPPIF_02125 6.1e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHHNPPIF_02128 1.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHHNPPIF_02129 1.6e-91 yacP S RNA-binding protein containing a PIN domain
NHHNPPIF_02130 9.8e-155 degV S DegV family
NHHNPPIF_02132 4.7e-32 K helix-turn-helix
NHHNPPIF_02133 4.8e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHHNPPIF_02134 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHHNPPIF_02135 2.8e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NHHNPPIF_02136 3.1e-223 int2 L Belongs to the 'phage' integrase family
NHHNPPIF_02137 4.9e-41 S Helix-turn-helix domain
NHHNPPIF_02138 4.1e-200 L Replication initiation factor
NHHNPPIF_02139 2.6e-36
NHHNPPIF_02140 1e-06
NHHNPPIF_02141 3.2e-101 K DNA-binding helix-turn-helix protein
NHHNPPIF_02142 8.4e-38 K Transcriptional activator, Rgg GadR MutR family
NHHNPPIF_02143 8.8e-88 K Transcriptional activator, Rgg GadR MutR family
NHHNPPIF_02147 9.7e-155 V AAA domain, putative AbiEii toxin, Type IV TA system
NHHNPPIF_02148 2.5e-70 S ABC-2 family transporter protein
NHHNPPIF_02149 2.8e-13
NHHNPPIF_02150 9.1e-223 capA M Bacterial capsule synthesis protein
NHHNPPIF_02151 1.4e-38 gcvR T UPF0237 protein
NHHNPPIF_02152 8.7e-243 XK27_08635 S UPF0210 protein
NHHNPPIF_02153 1.5e-129 ais G Phosphoglycerate mutase
NHHNPPIF_02154 1.3e-137 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NHHNPPIF_02155 1.4e-99 acmA 3.2.1.17 NU amidase activity
NHHNPPIF_02156 5.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHHNPPIF_02157 3.6e-67 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHHNPPIF_02158 4.6e-287 dnaK O Heat shock 70 kDa protein
NHHNPPIF_02159 4.5e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHHNPPIF_02160 3.6e-137 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHHNPPIF_02161 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NHHNPPIF_02162 9.6e-72 hmpT S cog cog4720
NHHNPPIF_02164 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
NHHNPPIF_02165 7.4e-135 agrA KT phosphorelay signal transduction system
NHHNPPIF_02166 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
NHHNPPIF_02168 7.3e-237 mesE M Transport protein ComB
NHHNPPIF_02169 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHHNPPIF_02170 0.0 mdlB V abc transporter atp-binding protein
NHHNPPIF_02171 0.0 mdlA V abc transporter atp-binding protein
NHHNPPIF_02173 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
NHHNPPIF_02174 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHHNPPIF_02175 2.4e-66 yutD J protein conserved in bacteria
NHHNPPIF_02176 5.3e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NHHNPPIF_02178 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHHNPPIF_02179 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHHNPPIF_02180 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NHHNPPIF_02181 4.3e-47 ftsL D cell division protein FtsL
NHHNPPIF_02182 1.6e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHHNPPIF_02183 1.6e-65
NHHNPPIF_02184 7.4e-27
NHHNPPIF_02185 7.5e-30
NHHNPPIF_02186 8.7e-33 yhaI J Protein of unknown function (DUF805)
NHHNPPIF_02187 4.5e-18 D nuclear chromosome segregation
NHHNPPIF_02188 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHHNPPIF_02189 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHHNPPIF_02190 5.8e-286 XK27_00765
NHHNPPIF_02191 8.1e-134 ecsA_2 V abc transporter atp-binding protein
NHHNPPIF_02192 5.2e-125 S Protein of unknown function (DUF554)
NHHNPPIF_02193 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NHHNPPIF_02194 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NHHNPPIF_02195 2.4e-55 liaI S membrane
NHHNPPIF_02196 2.7e-09 XK27_02470 K LytTr DNA-binding domain protein
NHHNPPIF_02197 3e-53 KT response to antibiotic
NHHNPPIF_02198 1.4e-08 KT response to antibiotic
NHHNPPIF_02199 9.1e-18 KT response to antibiotic
NHHNPPIF_02200 9.8e-80 yebC M Membrane
NHHNPPIF_02201 1.1e-16 yebC M Membrane
NHHNPPIF_02202 1.2e-258 XK27_03190 S hydrolases of the HAD superfamily
NHHNPPIF_02203 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NHHNPPIF_02204 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHHNPPIF_02205 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHHNPPIF_02206 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHHNPPIF_02207 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHHNPPIF_02208 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHHNPPIF_02209 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHHNPPIF_02211 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHHNPPIF_02212 9.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NHHNPPIF_02213 0.0 scrA 2.7.1.211 G pts system
NHHNPPIF_02214 2.3e-289 scrB 3.2.1.26 GH32 G invertase
NHHNPPIF_02215 9.2e-178 scrR K Transcriptional
NHHNPPIF_02216 3.6e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHHNPPIF_02217 3.4e-62 yqhY S protein conserved in bacteria
NHHNPPIF_02218 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHHNPPIF_02219 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
NHHNPPIF_02220 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NHHNPPIF_02223 7.7e-11 V 'abc transporter, ATP-binding protein
NHHNPPIF_02224 1.3e-58 V 'abc transporter, ATP-binding protein
NHHNPPIF_02230 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHHNPPIF_02231 5e-168 corA P COG0598 Mg2 and Co2 transporters
NHHNPPIF_02232 2e-123 XK27_01040 S Pfam PF06570
NHHNPPIF_02234 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHHNPPIF_02235 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHHNPPIF_02236 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NHHNPPIF_02237 2.1e-41 XK27_05745
NHHNPPIF_02239 3.6e-229 mutY L A G-specific adenine glycosylase
NHHNPPIF_02243 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHHNPPIF_02244 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHHNPPIF_02245 6.7e-93 cvpA S toxin biosynthetic process
NHHNPPIF_02246 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHHNPPIF_02247 4e-163 S Uncharacterised protein family (UPF0236)
NHHNPPIF_02248 2.9e-07
NHHNPPIF_02249 3.6e-111 D CobQ CobB MinD ParA nucleotide binding domain protein
NHHNPPIF_02250 3.5e-71 tnpR L Resolvase, N terminal domain
NHHNPPIF_02251 8.4e-184 U Relaxase/Mobilisation nuclease domain
NHHNPPIF_02252 8.5e-275 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHHNPPIF_02253 0.0 L Psort location Cytoplasmic, score
NHHNPPIF_02255 1.4e-44 S Bacterial mobilisation protein (MobC)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)