ORF_ID e_value Gene_name EC_number CAZy COGs Description
IIAPBPCI_00001 1.3e-94 L Transposase
IIAPBPCI_00002 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IIAPBPCI_00003 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IIAPBPCI_00006 3e-47 spiA K sequence-specific DNA binding
IIAPBPCI_00007 9.5e-140 blpT
IIAPBPCI_00016 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
IIAPBPCI_00023 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
IIAPBPCI_00024 7.4e-135 agrA KT phosphorelay signal transduction system
IIAPBPCI_00025 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
IIAPBPCI_00027 7.3e-237 mesE M Transport protein ComB
IIAPBPCI_00028 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAPBPCI_00030 0.0 mdlB V abc transporter atp-binding protein
IIAPBPCI_00031 0.0 mdlA V abc transporter atp-binding protein
IIAPBPCI_00033 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
IIAPBPCI_00034 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IIAPBPCI_00035 2.4e-66 yutD J protein conserved in bacteria
IIAPBPCI_00036 5.3e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IIAPBPCI_00038 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIAPBPCI_00039 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIAPBPCI_00040 0.0 ftsI 3.4.16.4 M penicillin-binding protein
IIAPBPCI_00041 4.3e-47 ftsL D cell division protein FtsL
IIAPBPCI_00042 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIAPBPCI_00043 1.6e-65
IIAPBPCI_00044 7.4e-27
IIAPBPCI_00045 7.5e-30
IIAPBPCI_00046 8.7e-33 yhaI J Protein of unknown function (DUF805)
IIAPBPCI_00047 4.5e-18 D nuclear chromosome segregation
IIAPBPCI_00048 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IIAPBPCI_00049 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIAPBPCI_00050 5.8e-286 XK27_00765
IIAPBPCI_00051 8.1e-134 ecsA_2 V abc transporter atp-binding protein
IIAPBPCI_00052 5.2e-125 S Protein of unknown function (DUF554)
IIAPBPCI_00053 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IIAPBPCI_00054 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IIAPBPCI_00055 2.4e-55 liaI S membrane
IIAPBPCI_00056 2.7e-09 XK27_02470 K LytTr DNA-binding domain protein
IIAPBPCI_00057 3e-53 KT response to antibiotic
IIAPBPCI_00058 1.4e-08 KT response to antibiotic
IIAPBPCI_00059 9.1e-18 KT response to antibiotic
IIAPBPCI_00060 9.8e-80 yebC M Membrane
IIAPBPCI_00061 1.1e-16 yebC M Membrane
IIAPBPCI_00062 1.2e-258 XK27_03190 S hydrolases of the HAD superfamily
IIAPBPCI_00063 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IIAPBPCI_00064 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIAPBPCI_00065 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIAPBPCI_00066 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIAPBPCI_00067 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IIAPBPCI_00068 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IIAPBPCI_00069 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIAPBPCI_00071 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIAPBPCI_00072 9.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
IIAPBPCI_00073 0.0 scrA 2.7.1.211 G pts system
IIAPBPCI_00074 2.3e-289 scrB 3.2.1.26 GH32 G invertase
IIAPBPCI_00075 9.2e-178 scrR K Transcriptional
IIAPBPCI_00076 3.6e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIAPBPCI_00077 3.4e-62 yqhY S protein conserved in bacteria
IIAPBPCI_00078 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIAPBPCI_00079 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
IIAPBPCI_00080 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
IIAPBPCI_00083 7.7e-11 V 'abc transporter, ATP-binding protein
IIAPBPCI_00084 1.3e-58 V 'abc transporter, ATP-binding protein
IIAPBPCI_00090 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IIAPBPCI_00091 5e-168 corA P COG0598 Mg2 and Co2 transporters
IIAPBPCI_00092 2e-123 XK27_01040 S Pfam PF06570
IIAPBPCI_00094 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIAPBPCI_00095 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIAPBPCI_00096 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
IIAPBPCI_00097 2.1e-41 XK27_05745
IIAPBPCI_00099 3.6e-229 mutY L A G-specific adenine glycosylase
IIAPBPCI_00103 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIAPBPCI_00104 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIAPBPCI_00105 6.7e-93 cvpA S toxin biosynthetic process
IIAPBPCI_00106 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IIAPBPCI_00107 4e-163 S Uncharacterised protein family (UPF0236)
IIAPBPCI_00108 2.9e-07
IIAPBPCI_00109 3.6e-111 D CobQ CobB MinD ParA nucleotide binding domain protein
IIAPBPCI_00110 3.5e-71 tnpR L Resolvase, N terminal domain
IIAPBPCI_00111 3.3e-260 U Relaxase/Mobilisation nuclease domain
IIAPBPCI_00112 1.4e-44 S Bacterial mobilisation protein (MobC)
IIAPBPCI_00114 0.0 L Psort location Cytoplasmic, score
IIAPBPCI_00115 8.5e-275 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIAPBPCI_00116 1.6e-07
IIAPBPCI_00117 2.6e-311 U Type IV secretory system Conjugative DNA transfer
IIAPBPCI_00118 4.7e-62
IIAPBPCI_00119 1.8e-28 MU outer membrane autotransporter barrel domain protein
IIAPBPCI_00120 7.9e-65
IIAPBPCI_00122 3.7e-64
IIAPBPCI_00123 0.0 M CHAP domain protein
IIAPBPCI_00124 0.0 U Psort location Cytoplasmic, score
IIAPBPCI_00125 1.5e-13 S PrgI family protein
IIAPBPCI_00127 9.6e-103
IIAPBPCI_00129 1.4e-34 S Transcriptional Coactivator p15 (PC4)
IIAPBPCI_00130 2.2e-46
IIAPBPCI_00131 2.4e-103 repA S Replication initiator protein A (RepA) N-terminus
IIAPBPCI_00133 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIAPBPCI_00134 1.9e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IIAPBPCI_00135 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIAPBPCI_00136 8.8e-48 azlD E branched-chain amino acid
IIAPBPCI_00137 8.5e-117 azlC E AzlC protein
IIAPBPCI_00138 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIAPBPCI_00139 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IIAPBPCI_00140 2.1e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
IIAPBPCI_00141 2.5e-33 ykzG S Belongs to the UPF0356 family
IIAPBPCI_00142 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIAPBPCI_00143 3.2e-41 pscB M CHAP domain protein
IIAPBPCI_00145 9.9e-263 glnA 6.3.1.2 E glutamine synthetase
IIAPBPCI_00146 8.5e-63 glnR K Transcriptional regulator
IIAPBPCI_00147 1.3e-87 S Fusaric acid resistance protein-like
IIAPBPCI_00148 1.5e-12
IIAPBPCI_00149 2.4e-30
IIAPBPCI_00150 1.7e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IIAPBPCI_00151 7.9e-41 L COG1943 Transposase and inactivated derivatives
IIAPBPCI_00152 9.7e-43 L transposase activity
IIAPBPCI_00153 8.4e-18 L Transposase
IIAPBPCI_00154 4.7e-102 L Transposase and inactivated derivatives
IIAPBPCI_00155 4.1e-158 L COG2801 Transposase and inactivated derivatives
IIAPBPCI_00156 9.3e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIAPBPCI_00157 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIAPBPCI_00158 4.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIAPBPCI_00159 5.1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIAPBPCI_00160 7e-142 purR 2.4.2.7 F operon repressor
IIAPBPCI_00161 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
IIAPBPCI_00162 4.5e-172 rmuC S RmuC domain protein
IIAPBPCI_00163 9.2e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
IIAPBPCI_00164 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IIAPBPCI_00165 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIAPBPCI_00167 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIAPBPCI_00168 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIAPBPCI_00169 4.1e-144 tatD L Hydrolase, tatd
IIAPBPCI_00170 1.9e-74 yccU S CoA-binding protein
IIAPBPCI_00171 1.1e-50 trxA O Belongs to the thioredoxin family
IIAPBPCI_00172 7.8e-143 S Macro domain protein
IIAPBPCI_00173 2.8e-13 L thioesterase
IIAPBPCI_00174 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
IIAPBPCI_00175 8.4e-232 L Transposase
IIAPBPCI_00179 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IIAPBPCI_00180 1.1e-83 L Transposase
IIAPBPCI_00181 1e-13 rpmH J Ribosomal protein L34
IIAPBPCI_00183 3.2e-184 jag S RNA-binding protein
IIAPBPCI_00184 8.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIAPBPCI_00185 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIAPBPCI_00186 1.2e-263 argH 4.3.2.1 E Argininosuccinate lyase
IIAPBPCI_00187 2.9e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IIAPBPCI_00188 1.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIAPBPCI_00189 1.6e-62 amiA E transmembrane transport
IIAPBPCI_00190 1.5e-181 amiA E ABC transporter, substrate-binding protein, family 5
IIAPBPCI_00191 1.8e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIAPBPCI_00192 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIAPBPCI_00193 3.5e-50 S Protein of unknown function (DUF3397)
IIAPBPCI_00194 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IIAPBPCI_00195 9.1e-29 WQ51_05710 S Mitochondrial biogenesis AIM24
IIAPBPCI_00196 3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
IIAPBPCI_00197 1.4e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
IIAPBPCI_00198 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIAPBPCI_00199 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IIAPBPCI_00200 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
IIAPBPCI_00201 4.6e-35 XK27_09620 S FMN reductase (NADPH) activity
IIAPBPCI_00202 7.4e-220 XK27_09615 C reductase
IIAPBPCI_00203 6.2e-91 fnt P Formate nitrite transporter
IIAPBPCI_00204 3.5e-32 XK27_08585 S Psort location CytoplasmicMembrane, score
IIAPBPCI_00205 4.7e-29 XK27_08585 S Psort location CytoplasmicMembrane, score
IIAPBPCI_00206 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IIAPBPCI_00207 4.8e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IIAPBPCI_00208 2.6e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IIAPBPCI_00209 1e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIAPBPCI_00210 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IIAPBPCI_00211 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IIAPBPCI_00212 7.8e-48 S glycolate biosynthetic process
IIAPBPCI_00213 1.7e-63 S phosphatase activity
IIAPBPCI_00214 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
IIAPBPCI_00217 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIAPBPCI_00218 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIAPBPCI_00219 6.4e-37 yeeD O sulfur carrier activity
IIAPBPCI_00220 2.8e-188 yeeE S Sulphur transport
IIAPBPCI_00221 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIAPBPCI_00222 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IIAPBPCI_00223 1.8e-09 S Domain of unknown function (DUF4651)
IIAPBPCI_00224 7.5e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IIAPBPCI_00225 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIAPBPCI_00226 2.1e-109 S CAAX amino terminal protease family protein
IIAPBPCI_00228 1.4e-66 V CAAX protease self-immunity
IIAPBPCI_00229 2.6e-26 lanR K sequence-specific DNA binding
IIAPBPCI_00230 3.2e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIAPBPCI_00231 4.2e-175 ytxK 2.1.1.72 L DNA methylase
IIAPBPCI_00232 2.2e-11 comGF U Putative Competence protein ComGF
IIAPBPCI_00233 1.3e-70 comGF U Competence protein ComGF
IIAPBPCI_00234 4.1e-15 NU Type II secretory pathway pseudopilin
IIAPBPCI_00235 2.6e-56 cglD NU Competence protein
IIAPBPCI_00236 2.5e-42 comGC U Required for transformation and DNA binding
IIAPBPCI_00237 4.5e-152 cglB NU type II secretion system
IIAPBPCI_00238 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IIAPBPCI_00239 2.7e-66 S cog cog4699
IIAPBPCI_00240 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAPBPCI_00241 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAPBPCI_00242 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIAPBPCI_00243 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIAPBPCI_00244 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IIAPBPCI_00245 1.1e-75 ilvN 2.2.1.6 E Acetolactate synthase
IIAPBPCI_00246 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
IIAPBPCI_00247 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IIAPBPCI_00248 6.7e-301 yloV S kinase related to dihydroxyacetone kinase
IIAPBPCI_00249 1.8e-57 asp S cog cog1302
IIAPBPCI_00250 2.7e-225 norN V Mate efflux family protein
IIAPBPCI_00251 1.9e-278 thrC 4.2.3.1 E Threonine synthase
IIAPBPCI_00252 2.6e-39 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IIAPBPCI_00253 2.3e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IIAPBPCI_00254 1.9e-156 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IIAPBPCI_00255 1.8e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
IIAPBPCI_00256 0.0 pepO 3.4.24.71 O Peptidase family M13
IIAPBPCI_00257 1.4e-114 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IIAPBPCI_00258 5.5e-80 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IIAPBPCI_00259 1.4e-54 treB 2.7.1.201 G PTS System
IIAPBPCI_00260 2.2e-20 treR K DNA-binding transcription factor activity
IIAPBPCI_00261 8.6e-87 treR K trehalose operon
IIAPBPCI_00262 2.2e-94 ywlG S Belongs to the UPF0340 family
IIAPBPCI_00265 3.2e-33 L PFAM Integrase, catalytic core
IIAPBPCI_00266 9.3e-72 L PFAM Integrase, catalytic core
IIAPBPCI_00267 2.4e-199 L Belongs to the 'phage' integrase family
IIAPBPCI_00268 4.4e-29 S Psort location Cytoplasmic, score 8.87
IIAPBPCI_00269 4.1e-31 S Helix-turn-helix domain
IIAPBPCI_00270 2.6e-53 phyR K Sigma-70, region 4
IIAPBPCI_00271 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
IIAPBPCI_00272 1.4e-63 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIAPBPCI_00273 1e-46 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
IIAPBPCI_00274 7.6e-154 L Integrase core domain protein
IIAPBPCI_00275 6.3e-38 L transposase activity
IIAPBPCI_00276 1.1e-199 EGP Major facilitator Superfamily
IIAPBPCI_00277 1.9e-32 spaC2 V Lanthionine synthetase C family protein
IIAPBPCI_00278 5.4e-197 L transposase, IS4 family
IIAPBPCI_00279 1.4e-15 tnp L DDE domain
IIAPBPCI_00280 2.1e-08 L Transposase
IIAPBPCI_00281 1.2e-43
IIAPBPCI_00282 1.6e-45
IIAPBPCI_00283 1.6e-206 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIAPBPCI_00284 3.3e-141 L Transposase
IIAPBPCI_00285 1.9e-13
IIAPBPCI_00286 2.8e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
IIAPBPCI_00288 1.6e-103 6.3.2.2 H ergothioneine biosynthetic process
IIAPBPCI_00289 7.3e-34 6.3.2.2 H gamma-glutamylcysteine synthetase
IIAPBPCI_00290 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
IIAPBPCI_00291 2.7e-13 L PFAM Integrase, catalytic core
IIAPBPCI_00292 1.6e-71 L PFAM Integrase, catalytic core
IIAPBPCI_00293 3.3e-62 rplQ J ribosomal protein l17
IIAPBPCI_00294 6.2e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAPBPCI_00295 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIAPBPCI_00296 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIAPBPCI_00297 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IIAPBPCI_00298 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIAPBPCI_00299 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIAPBPCI_00300 3.6e-201 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIAPBPCI_00301 1.3e-57 rplO J binds to the 23S rRNA
IIAPBPCI_00302 2.5e-23 rpmD J ribosomal protein l30
IIAPBPCI_00303 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIAPBPCI_00304 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIAPBPCI_00305 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIAPBPCI_00306 1.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIAPBPCI_00307 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIAPBPCI_00308 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIAPBPCI_00309 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIAPBPCI_00310 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIAPBPCI_00311 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIAPBPCI_00312 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
IIAPBPCI_00313 1e-69 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIAPBPCI_00314 7.5e-115 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIAPBPCI_00315 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIAPBPCI_00316 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIAPBPCI_00317 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIAPBPCI_00318 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIAPBPCI_00319 7.4e-104 rplD J Forms part of the polypeptide exit tunnel
IIAPBPCI_00320 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIAPBPCI_00321 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
IIAPBPCI_00322 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIAPBPCI_00323 0.0 XK27_09800 I Acyltransferase
IIAPBPCI_00324 1.7e-35 XK27_09805 S MORN repeat protein
IIAPBPCI_00325 5.2e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIAPBPCI_00326 3.6e-70 L Transposase
IIAPBPCI_00327 1.1e-144 L Transposase
IIAPBPCI_00328 7.8e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIAPBPCI_00329 1.1e-89 adk 2.7.4.3 F topology modulation protein
IIAPBPCI_00330 2.2e-186 yxaM EGP Major facilitator Superfamily
IIAPBPCI_00331 1.3e-196 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
IIAPBPCI_00332 5.3e-206 L Transposase
IIAPBPCI_00333 1.7e-48 adk 2.7.4.3 F topology modulation protein
IIAPBPCI_00334 1.7e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIAPBPCI_00335 9.7e-30 S Domain of unknown function (DUF4649)
IIAPBPCI_00336 3.9e-127 Z012_04635 K sequence-specific DNA binding
IIAPBPCI_00338 3.6e-232 C Radical SAM
IIAPBPCI_00339 5.6e-286 V ABC transporter transmembrane region
IIAPBPCI_00340 2.5e-89 K sequence-specific DNA binding
IIAPBPCI_00341 2.9e-155 L Replication initiation factor
IIAPBPCI_00342 1.9e-18 S Domain of unknown function (DUF3173)
IIAPBPCI_00343 7.7e-216 int L Belongs to the 'phage' integrase family
IIAPBPCI_00345 1.1e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
IIAPBPCI_00346 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IIAPBPCI_00347 1.4e-43 yrzL S Belongs to the UPF0297 family
IIAPBPCI_00348 6.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIAPBPCI_00349 4.2e-44 yrzB S Belongs to the UPF0473 family
IIAPBPCI_00350 2.6e-297 ccs S the current gene model (or a revised gene model) may contain a frame shift
IIAPBPCI_00351 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IIAPBPCI_00352 7.5e-14
IIAPBPCI_00353 2.6e-91 XK27_10930 K acetyltransferase
IIAPBPCI_00354 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIAPBPCI_00355 2.4e-147 yaaA S Belongs to the UPF0246 family
IIAPBPCI_00356 9.9e-169 XK27_01785 S cog cog1284
IIAPBPCI_00357 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IIAPBPCI_00359 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
IIAPBPCI_00360 5.7e-52 metE 2.1.1.14 E Methionine synthase
IIAPBPCI_00361 7.6e-64 metE 2.1.1.14 E Methionine synthase
IIAPBPCI_00362 9.2e-36 metE 2.1.1.14 E Methionine synthase
IIAPBPCI_00363 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IIAPBPCI_00364 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IIAPBPCI_00367 3.9e-115 yegS 2.7.1.107 I Diacylglycerol kinase
IIAPBPCI_00368 2.9e-15 yegS 2.7.1.107 I Diacylglycerol kinase
IIAPBPCI_00369 3.6e-95 S Hydrophobic domain protein
IIAPBPCI_00371 3.7e-27 S Membrane
IIAPBPCI_00372 1.7e-99
IIAPBPCI_00373 1.8e-23 S Small integral membrane protein
IIAPBPCI_00374 6.5e-83 M Protein conserved in bacteria
IIAPBPCI_00375 9.2e-11 K CsbD-like
IIAPBPCI_00376 1.1e-107 nudL L hydrolase
IIAPBPCI_00377 4.8e-221 L Transposase
IIAPBPCI_00378 3e-48 K transcriptional regulator, PadR family
IIAPBPCI_00379 9.6e-08 XK27_06920 S Protein of unknown function (DUF1700)
IIAPBPCI_00380 9.1e-13 XK27_06920 S Protein of unknown function (DUF1700)
IIAPBPCI_00381 1.3e-106 S Putative adhesin
IIAPBPCI_00382 4e-158 XK27_06930 V domain protein
IIAPBPCI_00383 2.1e-94 XK27_06935 K transcriptional regulator
IIAPBPCI_00384 5.5e-11 ypaA M Membrane
IIAPBPCI_00385 2e-07
IIAPBPCI_00386 4.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIAPBPCI_00387 8.2e-48 veg S Biofilm formation stimulator VEG
IIAPBPCI_00388 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IIAPBPCI_00389 8.5e-73 rplI J binds to the 23S rRNA
IIAPBPCI_00390 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IIAPBPCI_00391 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIAPBPCI_00392 3.7e-76 F NUDIX domain
IIAPBPCI_00393 3.2e-214 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIAPBPCI_00394 1.2e-300 S Bacterial membrane protein, YfhO
IIAPBPCI_00395 1.7e-63 isaA GH23 M Immunodominant staphylococcal antigen A
IIAPBPCI_00396 3.9e-80 lytE M LysM domain protein
IIAPBPCI_00397 1.6e-135 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAPBPCI_00398 7.6e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAPBPCI_00399 6.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAPBPCI_00400 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIAPBPCI_00401 7e-137 ymfM S sequence-specific DNA binding
IIAPBPCI_00402 4.7e-238 ymfH S Peptidase M16
IIAPBPCI_00403 4.5e-233 ymfF S Peptidase M16
IIAPBPCI_00404 3.6e-45 yaaA S S4 domain protein YaaA
IIAPBPCI_00405 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIAPBPCI_00406 4.7e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IIAPBPCI_00407 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IIAPBPCI_00408 3.4e-124 yvjA S membrane
IIAPBPCI_00409 6.7e-306 ybiT S abc transporter atp-binding protein
IIAPBPCI_00410 0.0 XK27_10405 S Bacterial membrane protein YfhO
IIAPBPCI_00414 1.8e-119 yoaK S Psort location CytoplasmicMembrane, score
IIAPBPCI_00415 7.4e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIAPBPCI_00416 5.6e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IIAPBPCI_00417 1.4e-133 parB K Belongs to the ParB family
IIAPBPCI_00418 4.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIAPBPCI_00419 8.2e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIAPBPCI_00420 4.1e-29 yyzM S Protein conserved in bacteria
IIAPBPCI_00421 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIAPBPCI_00422 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIAPBPCI_00423 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIAPBPCI_00424 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IIAPBPCI_00425 2.7e-61 divIC D Septum formation initiator
IIAPBPCI_00427 1.5e-239 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
IIAPBPCI_00428 1.2e-238 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIAPBPCI_00429 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IIAPBPCI_00430 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIAPBPCI_00431 1.7e-162 L Transposase
IIAPBPCI_00432 3.3e-43 L transposase activity
IIAPBPCI_00433 2.9e-18 L Transposase
IIAPBPCI_00434 4e-102 L Transposase and inactivated derivatives
IIAPBPCI_00447 5.3e-11
IIAPBPCI_00453 3.6e-138 mreC M Involved in formation and maintenance of cell shape
IIAPBPCI_00454 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IIAPBPCI_00455 2e-96 usp 3.5.1.28 CBM50 S CHAP domain
IIAPBPCI_00456 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIAPBPCI_00457 7.3e-26
IIAPBPCI_00458 5.5e-217 araT 2.6.1.1 E Aminotransferase
IIAPBPCI_00459 1e-142 recO L Involved in DNA repair and RecF pathway recombination
IIAPBPCI_00460 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIAPBPCI_00461 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIAPBPCI_00462 4.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IIAPBPCI_00463 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIAPBPCI_00464 8.6e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IIAPBPCI_00465 3.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IIAPBPCI_00466 5.2e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IIAPBPCI_00467 1.4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IIAPBPCI_00468 5.1e-78 L transposase activity
IIAPBPCI_00469 7.2e-31 L transposition
IIAPBPCI_00470 3.8e-31 L Integrase core domain protein
IIAPBPCI_00471 7.5e-160 S CHAP domain
IIAPBPCI_00472 2e-241 purD 6.3.4.13 F Belongs to the GARS family
IIAPBPCI_00473 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IIAPBPCI_00474 8.5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIAPBPCI_00475 2e-140 1.1.1.169 H Ketopantoate reductase
IIAPBPCI_00476 1.2e-32
IIAPBPCI_00477 3.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIAPBPCI_00478 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IIAPBPCI_00479 6.7e-215 sip L Belongs to the 'phage' integrase family
IIAPBPCI_00480 6e-39 K Helix-turn-helix
IIAPBPCI_00481 5.5e-17 K TRANSCRIPTIONal
IIAPBPCI_00486 9e-22
IIAPBPCI_00487 1.7e-154 KL Phage plasmid primase P4 family
IIAPBPCI_00488 3.8e-295 S DNA primase
IIAPBPCI_00491 2.8e-08
IIAPBPCI_00493 1.1e-52
IIAPBPCI_00494 8.2e-70 argR K Regulates arginine biosynthesis genes
IIAPBPCI_00495 1.5e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IIAPBPCI_00496 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIAPBPCI_00497 2.3e-78 S Protein of unknown function (DUF3021)
IIAPBPCI_00498 7.9e-68 K LytTr DNA-binding domain
IIAPBPCI_00500 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIAPBPCI_00502 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIAPBPCI_00503 7.8e-105 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
IIAPBPCI_00504 1e-229 cinA 3.5.1.42 S Belongs to the CinA family
IIAPBPCI_00505 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIAPBPCI_00506 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
IIAPBPCI_00512 2.6e-10
IIAPBPCI_00515 1.9e-07
IIAPBPCI_00520 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIAPBPCI_00521 2.8e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IIAPBPCI_00522 1.6e-35 XK27_02060 S Transglycosylase associated protein
IIAPBPCI_00523 4.4e-55 badR K DNA-binding transcription factor activity
IIAPBPCI_00524 6e-97 S reductase
IIAPBPCI_00525 1.2e-32 L Integrase core domain protein
IIAPBPCI_00527 1.5e-172 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IIAPBPCI_00529 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
IIAPBPCI_00530 3e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIAPBPCI_00531 9.3e-83 S Putative small multi-drug export protein
IIAPBPCI_00532 6.2e-76 ctsR K Belongs to the CtsR family
IIAPBPCI_00533 0.0 clpC O Belongs to the ClpA ClpB family
IIAPBPCI_00534 5.6e-129 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIAPBPCI_00535 3.9e-59 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIAPBPCI_00536 2.1e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIAPBPCI_00537 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IIAPBPCI_00538 5e-142 S SseB protein N-terminal domain
IIAPBPCI_00539 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
IIAPBPCI_00540 6.6e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIAPBPCI_00541 6.1e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIAPBPCI_00544 1.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIAPBPCI_00545 1.6e-91 yacP S RNA-binding protein containing a PIN domain
IIAPBPCI_00546 9.8e-155 degV S DegV family
IIAPBPCI_00548 4.7e-32 K helix-turn-helix
IIAPBPCI_00549 4.8e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIAPBPCI_00550 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIAPBPCI_00551 2.8e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IIAPBPCI_00552 3.1e-223 int2 L Belongs to the 'phage' integrase family
IIAPBPCI_00553 4.9e-41 S Helix-turn-helix domain
IIAPBPCI_00554 4.1e-200 L Replication initiation factor
IIAPBPCI_00555 2.6e-36
IIAPBPCI_00556 1e-06
IIAPBPCI_00557 3.2e-101 K DNA-binding helix-turn-helix protein
IIAPBPCI_00558 8.4e-38 K Transcriptional activator, Rgg GadR MutR family
IIAPBPCI_00559 8.8e-88 K Transcriptional activator, Rgg GadR MutR family
IIAPBPCI_00563 9.7e-155 V AAA domain, putative AbiEii toxin, Type IV TA system
IIAPBPCI_00564 2.5e-70 S ABC-2 family transporter protein
IIAPBPCI_00565 2.8e-13
IIAPBPCI_00566 9.1e-223 capA M Bacterial capsule synthesis protein
IIAPBPCI_00567 1.4e-38 gcvR T UPF0237 protein
IIAPBPCI_00568 8.7e-243 XK27_08635 S UPF0210 protein
IIAPBPCI_00569 1.5e-129 ais G Phosphoglycerate mutase
IIAPBPCI_00570 1.3e-137 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IIAPBPCI_00571 1.4e-99 acmA 3.2.1.17 NU amidase activity
IIAPBPCI_00572 5.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIAPBPCI_00573 3.6e-67 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIAPBPCI_00574 4.6e-287 dnaK O Heat shock 70 kDa protein
IIAPBPCI_00575 4.5e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIAPBPCI_00576 3.6e-137 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIAPBPCI_00577 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
IIAPBPCI_00578 9.6e-72 hmpT S cog cog4720
IIAPBPCI_00581 9e-215 L Transposase
IIAPBPCI_00582 1.6e-77 sigH K DNA-templated transcription, initiation
IIAPBPCI_00583 1.6e-146 ykuT M mechanosensitive ion channel
IIAPBPCI_00584 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIAPBPCI_00585 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIAPBPCI_00586 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIAPBPCI_00587 4.2e-83 XK27_03960 S Protein of unknown function (DUF3013)
IIAPBPCI_00588 3.4e-19 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IIAPBPCI_00589 5.2e-20
IIAPBPCI_00590 5.8e-141 repA S Replication initiator protein A (RepA) N-terminus
IIAPBPCI_00591 3.3e-258 hpaIIM 2.1.1.37 H cytosine-specific methyltransferase
IIAPBPCI_00592 1.4e-74 XK27_00590
IIAPBPCI_00593 1e-63 XK27_00585 P arsenate reductase (glutaredoxin) activity
IIAPBPCI_00594 1.5e-36 XK27_00580
IIAPBPCI_00595 1e-91 ypbD S CAAX protease self-immunity
IIAPBPCI_00596 1.3e-79 XK27_00570
IIAPBPCI_00597 0.0 traG U Type IV secretory system Conjugative DNA transfer
IIAPBPCI_00598 9.2e-34 XK27_00560
IIAPBPCI_00599 2.6e-139
IIAPBPCI_00600 1.5e-61 XK27_00550 S PrgI family protein
IIAPBPCI_00601 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
IIAPBPCI_00602 0.0 XK27_00530 S CHAP domain
IIAPBPCI_00603 6e-149 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
IIAPBPCI_00604 6.8e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
IIAPBPCI_00605 0.0 XK27_00515 D Glucan-binding protein C
IIAPBPCI_00606 5.1e-11 XK27_00510
IIAPBPCI_00607 7.8e-89 XK27_00505
IIAPBPCI_00608 0.0 XK27_00500 L SNF2 family N-terminal domain
IIAPBPCI_00609 0.0 L reverse transcriptase
IIAPBPCI_00610 8.1e-241 XK27_00500 L SNF2 family N-terminal domain
IIAPBPCI_00611 2.4e-44
IIAPBPCI_00612 2.3e-31
IIAPBPCI_00613 5.3e-45 L DNA synthesis involved in DNA repair
IIAPBPCI_00614 3.5e-18 V endonuclease activity
IIAPBPCI_00615 9.9e-104 XK27_10865
IIAPBPCI_00616 2.7e-11 L Protein of unknown function (DUF3991)
IIAPBPCI_00617 1.3e-149 L Toprim-like
IIAPBPCI_00618 1.1e-17 XK27_10875
IIAPBPCI_00619 2.9e-58 XK27_10880
IIAPBPCI_00620 2.3e-39
IIAPBPCI_00621 1.1e-281 L Transposase DDE domain
IIAPBPCI_00622 2.6e-130 2.7.1.176 O Zeta toxin
IIAPBPCI_00623 5.8e-40 vrlR S Domain of unknown function (DUF1837)
IIAPBPCI_00624 2.3e-190 vrlS L DEAD DEAH box helicase
IIAPBPCI_00625 8.9e-49 V Restriction endonuclease
IIAPBPCI_00626 1.7e-52
IIAPBPCI_00627 2.1e-50 S Bacterial mobilisation protein (MobC)
IIAPBPCI_00628 4.1e-299 U relaxase
IIAPBPCI_00629 1.2e-19
IIAPBPCI_00630 3.3e-21 blpS KT phosphorelay signal transduction system
IIAPBPCI_00631 2.6e-103 blpR KT LytTr DNA-binding domain
IIAPBPCI_00632 4.5e-122 blpH 2.7.13.3 T GHKL domain
IIAPBPCI_00634 1.3e-145 mesE M HlyD family secretion protein
IIAPBPCI_00635 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAPBPCI_00636 4.3e-18 comA V Papain-like cysteine protease AvrRpt2
IIAPBPCI_00637 1.6e-12 S Bacteriocin class II with double-glycine leader peptide
IIAPBPCI_00639 1.4e-75 L transposase activity
IIAPBPCI_00640 4.1e-33 L Integrase core domain
IIAPBPCI_00641 9.3e-75 L Transposase and inactivated derivatives
IIAPBPCI_00642 1.2e-47 blpT
IIAPBPCI_00643 5.1e-77 S CAAX protease self-immunity
IIAPBPCI_00645 6.1e-19 K Psort location Cytoplasmic, score
IIAPBPCI_00647 9.2e-236 L Psort location Cytoplasmic, score
IIAPBPCI_00648 1.8e-189 L Resolvase, N-terminal domain protein
IIAPBPCI_00649 1.7e-167 L Recombinase
IIAPBPCI_00650 7.3e-39 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IIAPBPCI_00651 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
IIAPBPCI_00652 3.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIAPBPCI_00653 1.5e-35 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IIAPBPCI_00654 1.5e-97 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IIAPBPCI_00655 1e-241 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IIAPBPCI_00656 5.3e-83 nrdI F Belongs to the NrdI family
IIAPBPCI_00657 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIAPBPCI_00658 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIAPBPCI_00659 2e-08 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IIAPBPCI_00660 3e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IIAPBPCI_00661 2.3e-18 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IIAPBPCI_00662 7.7e-40 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IIAPBPCI_00663 7.3e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IIAPBPCI_00664 1.2e-111 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIAPBPCI_00665 4.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IIAPBPCI_00666 7.9e-200 yhjX P Major Facilitator
IIAPBPCI_00667 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIAPBPCI_00668 5e-94 V VanZ like family
IIAPBPCI_00671 1e-123 glnQ E abc transporter atp-binding protein
IIAPBPCI_00672 1.8e-276 glnP P ABC transporter
IIAPBPCI_00673 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IIAPBPCI_00674 8.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IIAPBPCI_00675 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
IIAPBPCI_00676 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IIAPBPCI_00677 6.3e-235 sufD O assembly protein SufD
IIAPBPCI_00678 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IIAPBPCI_00679 2.1e-73 nifU C SUF system FeS assembly protein, NifU family
IIAPBPCI_00680 2.2e-273 sufB O assembly protein SufB
IIAPBPCI_00681 9.7e-19 oppA E ABC transporter substrate-binding protein
IIAPBPCI_00682 1.1e-125 oppA E ABC transporter substrate-binding protein
IIAPBPCI_00683 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIAPBPCI_00685 2.5e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIAPBPCI_00686 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIAPBPCI_00687 3e-27 oppD P Belongs to the ABC transporter superfamily
IIAPBPCI_00688 2.5e-32 oppD P Belongs to the ABC transporter superfamily
IIAPBPCI_00689 1.1e-68 oppD P Belongs to the ABC transporter superfamily
IIAPBPCI_00690 1.1e-43 oppD P Belongs to the ABC transporter superfamily
IIAPBPCI_00691 2.2e-61 oppF P Belongs to the ABC transporter superfamily
IIAPBPCI_00692 1.4e-87 oppF P Belongs to the ABC transporter superfamily
IIAPBPCI_00694 7.4e-10
IIAPBPCI_00695 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIAPBPCI_00696 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIAPBPCI_00697 3e-127 K sequence-specific DNA binding
IIAPBPCI_00698 0.0 KLT serine threonine protein kinase
IIAPBPCI_00699 1.9e-223 EGP Major facilitator Superfamily
IIAPBPCI_00700 3.1e-72 adcR K transcriptional
IIAPBPCI_00701 2.2e-136 adcC P ABC transporter, ATP-binding protein
IIAPBPCI_00702 1.9e-128 adcB P ABC transporter (Permease
IIAPBPCI_00703 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IIAPBPCI_00704 1.3e-64 ptsG 2.7.1.199, 2.7.1.208 G pts system
IIAPBPCI_00705 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
IIAPBPCI_00706 4.2e-257 ptsG 2.7.1.199, 2.7.1.208 G pts system
IIAPBPCI_00707 9.8e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
IIAPBPCI_00708 6.9e-256 pgi 5.3.1.9 G Belongs to the GPI family
IIAPBPCI_00709 1.9e-127 yeeN K transcriptional regulatory protein
IIAPBPCI_00710 2.4e-48 yajC U protein transport
IIAPBPCI_00711 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIAPBPCI_00712 5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
IIAPBPCI_00713 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IIAPBPCI_00714 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIAPBPCI_00715 0.0 WQ51_06230 S ABC transporter substrate binding protein
IIAPBPCI_00716 7.5e-141 cmpC S abc transporter atp-binding protein
IIAPBPCI_00717 3.2e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIAPBPCI_00718 1.1e-284 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIAPBPCI_00719 1.2e-61 L Transposase
IIAPBPCI_00720 1e-16 L Transposase
IIAPBPCI_00721 2.3e-48 L transposition
IIAPBPCI_00722 1.3e-31 L Integrase core domain protein
IIAPBPCI_00725 5.3e-16
IIAPBPCI_00726 2.2e-54 S TM2 domain
IIAPBPCI_00727 3.1e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIAPBPCI_00728 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIAPBPCI_00729 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IIAPBPCI_00730 2.2e-24 secE U Belongs to the SecE SEC61-gamma family
IIAPBPCI_00731 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
IIAPBPCI_00732 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
IIAPBPCI_00733 4e-47 cof Q phosphatase activity
IIAPBPCI_00734 2.1e-35 cof Q phosphatase activity
IIAPBPCI_00735 8.7e-99 glcR K transcriptional regulator (DeoR family)
IIAPBPCI_00736 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIAPBPCI_00738 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
IIAPBPCI_00739 8.3e-126 S COG1073 Hydrolases of the alpha beta superfamily
IIAPBPCI_00740 3.2e-275 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIAPBPCI_00741 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIAPBPCI_00742 3.2e-77 yhaI L Membrane
IIAPBPCI_00743 5.1e-259 pepC 3.4.22.40 E aminopeptidase
IIAPBPCI_00744 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIAPBPCI_00745 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIAPBPCI_00746 3.1e-95 ypsA S Belongs to the UPF0398 family
IIAPBPCI_00747 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIAPBPCI_00748 3.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IIAPBPCI_00749 4.7e-303 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IIAPBPCI_00750 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IIAPBPCI_00751 2.5e-23
IIAPBPCI_00752 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IIAPBPCI_00753 5.6e-52 XK27_09675 K -acetyltransferase
IIAPBPCI_00754 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IIAPBPCI_00755 4.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIAPBPCI_00756 2.6e-88 L Integrase core domain protein
IIAPBPCI_00757 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIAPBPCI_00758 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IIAPBPCI_00759 1.9e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIAPBPCI_00760 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
IIAPBPCI_00761 1.5e-97 ybhL S Belongs to the BI1 family
IIAPBPCI_00764 1.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IIAPBPCI_00765 2.4e-90 K transcriptional regulator
IIAPBPCI_00766 7.6e-36 yneF S UPF0154 protein
IIAPBPCI_00767 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IIAPBPCI_00768 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIAPBPCI_00769 3.5e-99 XK27_09740 S Phosphoesterase
IIAPBPCI_00770 7.8e-85 ykuL S CBS domain
IIAPBPCI_00771 2.8e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IIAPBPCI_00772 1.5e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIAPBPCI_00773 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIAPBPCI_00774 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIAPBPCI_00775 4e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IIAPBPCI_00776 4.8e-255 trkH P Cation transport protein
IIAPBPCI_00777 1.4e-245 trkA P Potassium transporter peripheral membrane component
IIAPBPCI_00778 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIAPBPCI_00779 5.5e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIAPBPCI_00780 1.1e-110 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
IIAPBPCI_00781 1.2e-160 K sequence-specific DNA binding
IIAPBPCI_00782 1.9e-33 V protein secretion by the type I secretion system
IIAPBPCI_00783 5.5e-105 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAPBPCI_00784 3.2e-75 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAPBPCI_00785 2.4e-85 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAPBPCI_00786 2.1e-30 yhaI L Membrane
IIAPBPCI_00787 1.5e-56 S Domain of unknown function (DUF4173)
IIAPBPCI_00788 3.4e-94 ureI S AmiS/UreI family transporter
IIAPBPCI_00789 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IIAPBPCI_00790 1.7e-53 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IIAPBPCI_00791 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IIAPBPCI_00792 6.6e-78 ureE O enzyme active site formation
IIAPBPCI_00793 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IIAPBPCI_00794 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IIAPBPCI_00795 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IIAPBPCI_00796 3.9e-176 cbiM P PDGLE domain
IIAPBPCI_00797 2.3e-134 P cobalt transport protein
IIAPBPCI_00798 3.1e-130 cbiO P ABC transporter
IIAPBPCI_00799 4.5e-152 ET amino acid transport
IIAPBPCI_00800 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAPBPCI_00801 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
IIAPBPCI_00802 3.8e-205 EGP Transmembrane secretion effector
IIAPBPCI_00803 1.8e-153 ET amino acid transport
IIAPBPCI_00804 5.4e-161 L Transposase
IIAPBPCI_00805 1e-50 L Transposase
IIAPBPCI_00806 2.3e-162 metQ M Belongs to the NlpA lipoprotein family
IIAPBPCI_00807 2.5e-77 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IIAPBPCI_00808 4.8e-76 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IIAPBPCI_00809 2.1e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IIAPBPCI_00810 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIAPBPCI_00811 8.8e-98 metI P ABC transporter (Permease
IIAPBPCI_00812 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IIAPBPCI_00813 4.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
IIAPBPCI_00814 8e-94 S UPF0397 protein
IIAPBPCI_00815 0.0 ykoD P abc transporter atp-binding protein
IIAPBPCI_00816 1.2e-149 cbiQ P cobalt transport
IIAPBPCI_00817 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIAPBPCI_00818 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
IIAPBPCI_00819 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
IIAPBPCI_00820 2.2e-241 P COG0168 Trk-type K transport systems, membrane components
IIAPBPCI_00821 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
IIAPBPCI_00822 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
IIAPBPCI_00823 3.9e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAPBPCI_00824 1.2e-275 T PhoQ Sensor
IIAPBPCI_00825 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIAPBPCI_00826 2.7e-216 dnaB L Replication initiation and membrane attachment
IIAPBPCI_00827 8.9e-167 dnaI L Primosomal protein DnaI
IIAPBPCI_00828 1.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IIAPBPCI_00829 8.3e-89 yrdC 3.5.1.19 Q isochorismatase
IIAPBPCI_00830 1.6e-105 L Transposase
IIAPBPCI_00831 3.9e-17 L Psort location Cytoplasmic, score
IIAPBPCI_00834 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIAPBPCI_00835 4.2e-62 manO S protein conserved in bacteria
IIAPBPCI_00836 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
IIAPBPCI_00837 3.9e-116 manM G pts system
IIAPBPCI_00838 2.4e-173 manL 2.7.1.191 G pts system
IIAPBPCI_00839 4.9e-139 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
IIAPBPCI_00840 5.6e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IIAPBPCI_00841 3e-241 pbuO S permease
IIAPBPCI_00842 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
IIAPBPCI_00843 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
IIAPBPCI_00844 1.5e-217 brpA K Transcriptional
IIAPBPCI_00845 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
IIAPBPCI_00846 3.1e-212 nusA K Participates in both transcription termination and antitermination
IIAPBPCI_00847 3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
IIAPBPCI_00848 1.4e-41 ylxQ J ribosomal protein
IIAPBPCI_00849 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIAPBPCI_00850 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIAPBPCI_00851 1.8e-45 yvdD 3.2.2.10 S Belongs to the LOG family
IIAPBPCI_00852 3.6e-219 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IIAPBPCI_00853 7.9e-274 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIAPBPCI_00854 1e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
IIAPBPCI_00855 2.3e-91 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
IIAPBPCI_00856 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
IIAPBPCI_00857 2.8e-221 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IIAPBPCI_00858 8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
IIAPBPCI_00859 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIAPBPCI_00860 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIAPBPCI_00861 1.3e-73 ylbF S Belongs to the UPF0342 family
IIAPBPCI_00862 7.1e-46 ylbG S UPF0298 protein
IIAPBPCI_00863 9.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IIAPBPCI_00864 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
IIAPBPCI_00865 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
IIAPBPCI_00866 6.2e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IIAPBPCI_00867 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IIAPBPCI_00868 1e-39 acuB S CBS domain
IIAPBPCI_00869 9.3e-42 acuB S IMP dehydrogenase activity
IIAPBPCI_00870 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IIAPBPCI_00871 6.3e-111 yvyE 3.4.13.9 S YigZ family
IIAPBPCI_00872 2e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IIAPBPCI_00873 4.9e-122 comFC S Competence protein
IIAPBPCI_00874 2.4e-90 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIAPBPCI_00881 3.2e-231 L Transposase
IIAPBPCI_00882 1e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
IIAPBPCI_00883 5.7e-222 L Transposase
IIAPBPCI_00884 4.1e-107 S Domain of unknown function (DUF1803)
IIAPBPCI_00885 7.8e-102 ygaC J Belongs to the UPF0374 family
IIAPBPCI_00886 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
IIAPBPCI_00887 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIAPBPCI_00888 6.7e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
IIAPBPCI_00889 5.9e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
IIAPBPCI_00890 1.6e-114 S Haloacid dehalogenase-like hydrolase
IIAPBPCI_00891 1e-137 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
IIAPBPCI_00892 2.3e-72 marR K Transcriptional regulator, MarR family
IIAPBPCI_00893 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIAPBPCI_00894 2.6e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIAPBPCI_00895 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
IIAPBPCI_00896 1.9e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IIAPBPCI_00897 1.6e-126 IQ reductase
IIAPBPCI_00898 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIAPBPCI_00899 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIAPBPCI_00900 4.3e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIAPBPCI_00901 1.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IIAPBPCI_00902 1.1e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIAPBPCI_00903 1.5e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IIAPBPCI_00904 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIAPBPCI_00905 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
IIAPBPCI_00906 1.8e-84 L Transposase
IIAPBPCI_00907 1.2e-121 fruR K transcriptional
IIAPBPCI_00908 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IIAPBPCI_00909 0.0 fruA 2.7.1.202 G phosphotransferase system
IIAPBPCI_00910 3e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IIAPBPCI_00911 1.5e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IIAPBPCI_00913 1.2e-208 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IIAPBPCI_00914 1.2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIAPBPCI_00915 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IIAPBPCI_00916 3e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IIAPBPCI_00917 4.9e-39 2.3.1.128 K acetyltransferase
IIAPBPCI_00918 6.4e-29 2.3.1.128 K acetyltransferase
IIAPBPCI_00919 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IIAPBPCI_00920 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IIAPBPCI_00921 6.7e-122 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIAPBPCI_00922 2.6e-64 WQ51_03320 S cog cog4835
IIAPBPCI_00923 6.4e-61 XK27_08360 S EDD domain protein, DegV family
IIAPBPCI_00924 5.5e-75 XK27_08360 S EDD domain protein, DegV family
IIAPBPCI_00925 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IIAPBPCI_00926 7.4e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIAPBPCI_00927 0.0 yfmR S abc transporter atp-binding protein
IIAPBPCI_00928 3.3e-25 U response to pH
IIAPBPCI_00929 1e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
IIAPBPCI_00930 1.2e-163 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IIAPBPCI_00931 6.9e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IIAPBPCI_00932 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IIAPBPCI_00933 7.2e-77 K DNA-binding transcription factor activity
IIAPBPCI_00934 0.0 lmrA1 V abc transporter atp-binding protein
IIAPBPCI_00935 0.0 lmrA2 V abc transporter atp-binding protein
IIAPBPCI_00936 1.4e-45 K Acetyltransferase (GNAT) family
IIAPBPCI_00937 4.5e-77 sptS 2.7.13.3 T Histidine kinase
IIAPBPCI_00938 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IIAPBPCI_00939 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIAPBPCI_00940 7e-161 cvfB S Protein conserved in bacteria
IIAPBPCI_00941 7.4e-35 yozE S Belongs to the UPF0346 family
IIAPBPCI_00942 1.4e-113 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
IIAPBPCI_00943 1.7e-60 rlpA M LysM domain protein
IIAPBPCI_00944 1e-190 phoH T phosphate starvation-inducible protein PhoH
IIAPBPCI_00948 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIAPBPCI_00949 3.5e-163 K transcriptional regulator (lysR family)
IIAPBPCI_00950 1.4e-186 coiA 3.6.4.12 S Competence protein
IIAPBPCI_00951 0.0 pepF E oligoendopeptidase F
IIAPBPCI_00952 7.1e-127 yrrM 2.1.1.104 S O-Methyltransferase
IIAPBPCI_00953 8.6e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
IIAPBPCI_00955 8.2e-96 repA S Replication initiator protein A (RepA) N-terminus
IIAPBPCI_00956 1.7e-38
IIAPBPCI_00957 4e-40 S Transcriptional Coactivator p15 (PC4)
IIAPBPCI_00959 3e-104
IIAPBPCI_00961 5e-12 S PrgI family protein
IIAPBPCI_00962 0.0 U Psort location Cytoplasmic, score
IIAPBPCI_00963 0.0 M CHAP domain protein
IIAPBPCI_00964 1.1e-104
IIAPBPCI_00966 8.5e-67
IIAPBPCI_00967 1e-29 MU outer membrane autotransporter barrel domain protein
IIAPBPCI_00968 5.5e-63
IIAPBPCI_00969 1.8e-310 U Type IV secretory system Conjugative DNA transfer
IIAPBPCI_00971 2.5e-274 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIAPBPCI_00972 0.0 L Toprim-like
IIAPBPCI_00974 3.3e-35 S Bacterial mobilisation protein (MobC)
IIAPBPCI_00975 9.6e-252 U Relaxase/Mobilisation nuclease domain
IIAPBPCI_00979 1.3e-73 tnpR L Resolvase, N terminal domain
IIAPBPCI_00981 4.5e-114 D CobQ CobB MinD ParA nucleotide binding domain protein
IIAPBPCI_00983 9.5e-126 S Fic/DOC family
IIAPBPCI_00984 8.9e-163 S Uncharacterised protein family (UPF0236)
IIAPBPCI_00985 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIAPBPCI_00986 2.5e-146 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IIAPBPCI_00987 3.4e-41 3.4.17.14, 3.5.1.28 NU amidase activity
IIAPBPCI_00988 1.3e-30 3.4.17.14, 3.5.1.28 NU amidase activity
IIAPBPCI_00989 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IIAPBPCI_00990 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IIAPBPCI_00991 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IIAPBPCI_00992 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IIAPBPCI_00993 1.2e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IIAPBPCI_00994 5.3e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IIAPBPCI_00995 2.5e-129 yxkH G deacetylase
IIAPBPCI_00996 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IIAPBPCI_00997 4.2e-150 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IIAPBPCI_00998 1e-151 rarD S Transporter
IIAPBPCI_00999 2.6e-16 T peptidase
IIAPBPCI_01000 8.9e-14 coiA 3.6.4.12 S Competence protein
IIAPBPCI_01001 8.3e-105 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IIAPBPCI_01002 8.1e-69 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIAPBPCI_01003 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIAPBPCI_01004 1.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIAPBPCI_01005 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
IIAPBPCI_01006 2.3e-76 atpF C ATP synthase F(0) sector subunit b
IIAPBPCI_01007 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIAPBPCI_01008 2.5e-278 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIAPBPCI_01009 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIAPBPCI_01010 6.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIAPBPCI_01011 2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IIAPBPCI_01012 7.5e-228 ftsW D Belongs to the SEDS family
IIAPBPCI_01013 3.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIAPBPCI_01014 3.4e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIAPBPCI_01015 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIAPBPCI_01016 1.1e-156 holB 2.7.7.7 L dna polymerase iii
IIAPBPCI_01017 8e-135 yaaT S stage 0 sporulation protein
IIAPBPCI_01018 9.5e-55 yabA L Involved in initiation control of chromosome replication
IIAPBPCI_01019 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIAPBPCI_01020 3.8e-232 L Transposase
IIAPBPCI_01021 3.7e-232 amt P Ammonium Transporter
IIAPBPCI_01022 1.2e-52 glnB K Belongs to the P(II) protein family
IIAPBPCI_01023 1.3e-103 mur1 NU mannosyl-glycoprotein
IIAPBPCI_01024 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
IIAPBPCI_01025 1.2e-92 nptA P COG1283 Na phosphate symporter
IIAPBPCI_01026 8e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IIAPBPCI_01027 4.9e-51
IIAPBPCI_01028 2.2e-25
IIAPBPCI_01029 3.9e-60
IIAPBPCI_01030 6.1e-63 S membrane
IIAPBPCI_01031 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IIAPBPCI_01032 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IIAPBPCI_01033 4.5e-39 ynzC S UPF0291 protein
IIAPBPCI_01034 9.7e-23 L Transposase
IIAPBPCI_01035 7.8e-21 L Transposase
IIAPBPCI_01036 1.1e-107 L Transposase
IIAPBPCI_01037 6.9e-251 cycA E permease
IIAPBPCI_01038 3.2e-09 uvrX 2.7.7.7 L impB/mucB/samB family
IIAPBPCI_01039 7.4e-25 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IIAPBPCI_01040 1.3e-181 pts33BCA G pts system
IIAPBPCI_01041 4.1e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIAPBPCI_01046 1.5e-166 fhuR K transcriptional regulator (lysR family)
IIAPBPCI_01047 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIAPBPCI_01048 5.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIAPBPCI_01049 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIAPBPCI_01050 4.9e-227 pyrP F uracil Permease
IIAPBPCI_01051 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IIAPBPCI_01052 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
IIAPBPCI_01053 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
IIAPBPCI_01054 2.1e-129 2.1.1.223 S Putative SAM-dependent methyltransferase
IIAPBPCI_01055 3.6e-35 V efflux transmembrane transporter activity
IIAPBPCI_01056 3.1e-31 V efflux transmembrane transporter activity
IIAPBPCI_01057 8.2e-28 ytrF V efflux transmembrane transporter activity
IIAPBPCI_01058 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIAPBPCI_01059 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIAPBPCI_01060 2.1e-19
IIAPBPCI_01061 4.5e-133 repA S Replication initiator protein A (RepA) N-terminus
IIAPBPCI_01062 4.8e-10
IIAPBPCI_01063 7.9e-260 hpaIIM 2.1.1.37 H cytosine-specific methyltransferase
IIAPBPCI_01064 1.6e-73 XK27_00590
IIAPBPCI_01065 1.9e-49
IIAPBPCI_01066 3.8e-37
IIAPBPCI_01067 3.9e-91 3.4.11.19 V CAAX protease self-immunity
IIAPBPCI_01068 1.1e-41
IIAPBPCI_01069 0.0 traG U COG3505 Type IV secretory pathway, VirD4 components
IIAPBPCI_01070 3.2e-34 XK27_00560
IIAPBPCI_01071 3.3e-139 XK27_00555
IIAPBPCI_01072 4.4e-53 XK27_00550 S PrgI family protein
IIAPBPCI_01073 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
IIAPBPCI_01074 1.5e-43 M CHAP domain protein
IIAPBPCI_01075 0.0 M CHAP domain protein
IIAPBPCI_01076 8.1e-108 abiGI K Transcriptional regulator, AbiEi antitoxin
IIAPBPCI_01077 3e-90 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
IIAPBPCI_01078 1.6e-34
IIAPBPCI_01079 1.1e-54
IIAPBPCI_01080 2.6e-56 S Bacterial mobilisation protein (MobC)
IIAPBPCI_01081 7.9e-73 U relaxase
IIAPBPCI_01082 2.3e-214 U relaxase
IIAPBPCI_01083 6.5e-169 T PhoQ Sensor
IIAPBPCI_01084 6.8e-93 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAPBPCI_01086 6.4e-205 V Lantibiotic transport processing ATP-binding protein
IIAPBPCI_01087 7.2e-116 bcrA V abc transporter atp-binding protein
IIAPBPCI_01088 9.7e-82 S ABC-2 family transporter protein
IIAPBPCI_01089 8.8e-72 S ABC-2 family transporter protein
IIAPBPCI_01090 6.1e-32 K transcriptional
IIAPBPCI_01091 1.2e-28 S Domain of unknown function (DUF3173)
IIAPBPCI_01092 8.9e-239 L Belongs to the 'phage' integrase family
IIAPBPCI_01093 9.1e-229 L Transposase
IIAPBPCI_01094 1.6e-18 L Integrase core domain
IIAPBPCI_01095 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
IIAPBPCI_01096 2.8e-164 hrtB V MacB-like periplasmic core domain
IIAPBPCI_01099 3e-92 S MucBP domain
IIAPBPCI_01100 6.5e-50 M YSIRK type signal peptide
IIAPBPCI_01101 0.0 M the current gene model (or a revised gene model) may contain a
IIAPBPCI_01103 0.0 mdlB V abc transporter atp-binding protein
IIAPBPCI_01104 0.0 lmrA V abc transporter atp-binding protein
IIAPBPCI_01105 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IIAPBPCI_01106 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIAPBPCI_01107 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
IIAPBPCI_01108 2.1e-131 rr02 KT response regulator
IIAPBPCI_01109 6.3e-27 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIAPBPCI_01110 1.1e-178 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIAPBPCI_01111 4.8e-168 V ABC transporter
IIAPBPCI_01112 5.4e-122 sagI S ABC-2 type transporter
IIAPBPCI_01113 3.4e-196 yceA S Belongs to the UPF0176 family
IIAPBPCI_01114 1.2e-26 XK27_00085 K Transcriptional
IIAPBPCI_01115 2.9e-17
IIAPBPCI_01116 5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
IIAPBPCI_01117 5.6e-113 S VIT family
IIAPBPCI_01118 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIAPBPCI_01119 5.7e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIAPBPCI_01120 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
IIAPBPCI_01121 9.1e-48 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IIAPBPCI_01122 1.3e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IIAPBPCI_01123 8.8e-104 GBS0088 J protein conserved in bacteria
IIAPBPCI_01124 4.6e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IIAPBPCI_01125 1.1e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IIAPBPCI_01126 3.1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
IIAPBPCI_01127 6.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIAPBPCI_01128 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIAPBPCI_01129 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
IIAPBPCI_01130 2.5e-21
IIAPBPCI_01131 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIAPBPCI_01133 3e-29 U protein secretion
IIAPBPCI_01134 1.8e-49 U protein secretion
IIAPBPCI_01135 2.5e-08 M Pilin isopeptide linkage domain protein
IIAPBPCI_01136 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
IIAPBPCI_01137 3.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IIAPBPCI_01138 3.5e-49 XK27_13030
IIAPBPCI_01139 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIAPBPCI_01140 7.1e-48 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIAPBPCI_01141 3.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIAPBPCI_01142 4e-164 S Protein of unknown function (DUF3114)
IIAPBPCI_01143 4.6e-22 S Protein of unknown function (DUF3114)
IIAPBPCI_01144 1.5e-118 yqfA K protein, Hemolysin III
IIAPBPCI_01145 1e-25 K hmm pf08876
IIAPBPCI_01146 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IIAPBPCI_01147 5e-218 mvaS 2.3.3.10 I synthase
IIAPBPCI_01148 1.9e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIAPBPCI_01149 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIAPBPCI_01150 9.7e-22
IIAPBPCI_01151 3.7e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIAPBPCI_01152 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IIAPBPCI_01153 9.2e-248 mmuP E amino acid
IIAPBPCI_01154 3.4e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
IIAPBPCI_01155 1.4e-29 S Domain of unknown function (DUF1912)
IIAPBPCI_01156 8.3e-15 L Helix-hairpin-helix DNA-binding motif class 1
IIAPBPCI_01157 1.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIAPBPCI_01158 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIAPBPCI_01159 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIAPBPCI_01160 3.4e-199 ilvE 2.6.1.42 E Aminotransferase
IIAPBPCI_01161 1.1e-15 S Protein of unknown function (DUF2969)
IIAPBPCI_01164 1.3e-202 rpsA 1.17.7.4 J ribosomal protein S1
IIAPBPCI_01167 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
IIAPBPCI_01168 6.1e-70 M Pfam SNARE associated Golgi protein
IIAPBPCI_01169 9.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
IIAPBPCI_01170 3e-51 S oxidoreductase
IIAPBPCI_01171 1.4e-41 S oxidoreductase
IIAPBPCI_01172 1.7e-07 yvaA 1.1.1.371 S inositol 2-dehydrogenase activity
IIAPBPCI_01173 2.4e-47 XK27_09445 S Domain of unknown function (DUF1827)
IIAPBPCI_01174 5.7e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IIAPBPCI_01175 0.0 clpE O Belongs to the ClpA ClpB family
IIAPBPCI_01176 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIAPBPCI_01177 1.3e-34 ykuJ S protein conserved in bacteria
IIAPBPCI_01178 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
IIAPBPCI_01179 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAPBPCI_01180 1.2e-77 feoA P FeoA domain protein
IIAPBPCI_01181 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IIAPBPCI_01182 1.5e-07
IIAPBPCI_01183 1.9e-33 yugF I carboxylic ester hydrolase activity
IIAPBPCI_01184 1.5e-23 I Alpha/beta hydrolase family
IIAPBPCI_01185 4.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIAPBPCI_01186 3.9e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIAPBPCI_01187 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
IIAPBPCI_01188 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIAPBPCI_01189 1.1e-43 licT K transcriptional antiterminator
IIAPBPCI_01190 1.8e-64 licT K antiterminator
IIAPBPCI_01191 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIAPBPCI_01192 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IIAPBPCI_01193 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIAPBPCI_01194 1.2e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIAPBPCI_01195 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIAPBPCI_01196 9.4e-220 mdtG EGP Major facilitator Superfamily
IIAPBPCI_01197 2.6e-33 secG U Preprotein translocase subunit SecG
IIAPBPCI_01198 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIAPBPCI_01199 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IIAPBPCI_01200 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIAPBPCI_01201 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
IIAPBPCI_01202 3.5e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
IIAPBPCI_01203 9.9e-183 ccpA K Catabolite control protein A
IIAPBPCI_01204 5.2e-27 yyaQ S YjbR
IIAPBPCI_01205 1.5e-45 yyaQ V Protein conserved in bacteria
IIAPBPCI_01206 2.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IIAPBPCI_01207 5.7e-77 yueI S Protein of unknown function (DUF1694)
IIAPBPCI_01208 8.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIAPBPCI_01209 2.5e-206 S Phage integrase family
IIAPBPCI_01210 1.7e-22 S Host cell surface-exposed lipoprotein
IIAPBPCI_01211 2.3e-20 E Zn peptidase
IIAPBPCI_01212 7.5e-53 S sequence-specific DNA binding
IIAPBPCI_01213 2.4e-28 S sequence-specific DNA binding
IIAPBPCI_01214 1.1e-137
IIAPBPCI_01215 1.8e-08 S ORF6C domain
IIAPBPCI_01216 2.3e-25
IIAPBPCI_01220 2.1e-85 L N-terminal phage replisome organiser (Phage_rep_org_N)
IIAPBPCI_01221 7.3e-133 S IstB-like ATP binding protein
IIAPBPCI_01223 1.1e-33 S ERF superfamily
IIAPBPCI_01224 8e-49 S Protein of unknown function (DUF1351)
IIAPBPCI_01225 6.6e-65 S Single-strand binding protein family
IIAPBPCI_01226 3.9e-78 S magnesium ion binding
IIAPBPCI_01228 3.9e-10
IIAPBPCI_01231 2.7e-31 S Protein of unknown function (DUF1642)
IIAPBPCI_01233 2e-30 S Protein of unknown function (DUF1642)
IIAPBPCI_01234 2.2e-30 S sequence-specific DNA binding
IIAPBPCI_01236 3.1e-24 S YopX protein
IIAPBPCI_01239 1.1e-31
IIAPBPCI_01240 5.5e-24 L DNA packaging
IIAPBPCI_01241 4.9e-240 S Terminase-like family
IIAPBPCI_01242 5.3e-249 S Phage portal protein, SPP1 Gp6-like
IIAPBPCI_01243 1.8e-111 S Phage Mu protein F like protein
IIAPBPCI_01244 3.5e-10 S Domain of unknown function (DUF4355)
IIAPBPCI_01245 2.4e-14
IIAPBPCI_01246 7.6e-178 S Phage major capsid protein E
IIAPBPCI_01248 2.1e-36 S Phage gp6-like head-tail connector protein
IIAPBPCI_01250 4e-43 S exonuclease activity
IIAPBPCI_01251 8.2e-61
IIAPBPCI_01252 3.4e-75 S Phage major tail protein 2
IIAPBPCI_01253 5e-57 S Pfam:Phage_TAC_12
IIAPBPCI_01255 2.6e-193 S peptidoglycan catabolic process
IIAPBPCI_01256 1.6e-171 S Phage tail protein
IIAPBPCI_01257 0.0 S peptidoglycan catabolic process
IIAPBPCI_01258 4e-308 S N-acetylmuramoyl-L-alanine amidase activity
IIAPBPCI_01262 2.8e-22 S COG5546 Small integral membrane protein
IIAPBPCI_01263 7.4e-115 M Bacteriophage peptidoglycan hydrolase
IIAPBPCI_01269 1.3e-24 WQ51_00785
IIAPBPCI_01270 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IIAPBPCI_01271 2.6e-219 ywbD 2.1.1.191 J Methyltransferase
IIAPBPCI_01272 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IIAPBPCI_01273 1.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIAPBPCI_01274 2.9e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IIAPBPCI_01275 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IIAPBPCI_01276 1.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IIAPBPCI_01277 3.2e-53 yheA S Belongs to the UPF0342 family
IIAPBPCI_01278 8.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IIAPBPCI_01279 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IIAPBPCI_01280 2.5e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IIAPBPCI_01281 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
IIAPBPCI_01282 9e-238 msrR K Transcriptional regulator
IIAPBPCI_01283 1.6e-155 ydiA P C4-dicarboxylate transporter malic acid transport protein
IIAPBPCI_01284 1.3e-201 I acyl-CoA dehydrogenase
IIAPBPCI_01285 1.1e-95 mip S hydroperoxide reductase activity
IIAPBPCI_01286 1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIAPBPCI_01287 1.7e-54 J Acetyltransferase (GNAT) domain
IIAPBPCI_01288 5.7e-95
IIAPBPCI_01289 8.4e-193 L Transposase
IIAPBPCI_01290 1.5e-37 L transposase activity
IIAPBPCI_01291 3.6e-154 L COG2801 Transposase and inactivated derivatives
IIAPBPCI_01292 8.9e-11
IIAPBPCI_01293 7.8e-59 S Protein of unknown function (DUF1722)
IIAPBPCI_01294 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
IIAPBPCI_01296 2.4e-33
IIAPBPCI_01297 1.7e-26 S CAAX protease self-immunity
IIAPBPCI_01298 1e-30 S CAAX protease self-immunity
IIAPBPCI_01299 1.9e-27 estA E GDSL-like Lipase/Acylhydrolase
IIAPBPCI_01300 2.1e-95
IIAPBPCI_01301 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IIAPBPCI_01302 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAPBPCI_01303 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAPBPCI_01304 6.7e-198 S CRISPR-associated protein Csn2 subfamily St
IIAPBPCI_01305 9.3e-147 ycgQ S TIGR03943 family
IIAPBPCI_01306 1.4e-156 XK27_03015 S permease
IIAPBPCI_01308 0.0 yhgF K Transcriptional accessory protein
IIAPBPCI_01309 1.9e-40 pspC KT PspC domain
IIAPBPCI_01310 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIAPBPCI_01311 1.5e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIAPBPCI_01313 1.2e-68 ytxH S General stress protein
IIAPBPCI_01315 1.7e-176 yegQ O Peptidase U32
IIAPBPCI_01316 3.4e-252 yegQ O Peptidase U32
IIAPBPCI_01317 2.7e-86 bioY S biotin synthase
IIAPBPCI_01319 1.1e-33 XK27_12190 S protein conserved in bacteria
IIAPBPCI_01320 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
IIAPBPCI_01322 5.1e-50 L Transposase
IIAPBPCI_01323 4.9e-165 L Transposase
IIAPBPCI_01324 3.5e-106 MA20_06410 E LysE type translocator
IIAPBPCI_01325 8.6e-70 IQ PFAM AMP-dependent synthetase and ligase
IIAPBPCI_01326 2e-219 L Transposase
IIAPBPCI_01327 2.6e-112 L Transposase
IIAPBPCI_01328 3.5e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IIAPBPCI_01329 1.9e-15 M LysM domain
IIAPBPCI_01330 2.4e-58 M LysM domain
IIAPBPCI_01331 3.1e-20
IIAPBPCI_01332 6.4e-173 S hydrolase
IIAPBPCI_01333 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
IIAPBPCI_01334 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIAPBPCI_01335 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
IIAPBPCI_01336 2.7e-27 P Hemerythrin HHE cation binding domain protein
IIAPBPCI_01337 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIAPBPCI_01338 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
IIAPBPCI_01339 7.9e-37 MA20_36090 S Protein of unknown function (DUF2974)
IIAPBPCI_01340 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
IIAPBPCI_01341 3.7e-48 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIAPBPCI_01342 1.7e-70 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIAPBPCI_01343 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IIAPBPCI_01344 8.7e-216 prrC S AAA domain
IIAPBPCI_01345 5e-125 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
IIAPBPCI_01346 4.8e-105
IIAPBPCI_01347 7.5e-135 S Protein conserved in bacteria
IIAPBPCI_01348 2.4e-303 hsdM 2.1.1.72 V type I restriction-modification system
IIAPBPCI_01349 1.2e-49 S PD-(D/E)XK nuclease family transposase
IIAPBPCI_01350 1.1e-90 S double-stranded DNA endodeoxyribonuclease activity
IIAPBPCI_01351 5.1e-163 spd F DNA RNA non-specific endonuclease
IIAPBPCI_01352 9e-93 lemA S LemA family
IIAPBPCI_01353 6.4e-133 htpX O Belongs to the peptidase M48B family
IIAPBPCI_01354 4.2e-75 S Psort location CytoplasmicMembrane, score
IIAPBPCI_01355 6.2e-56 S Domain of unknown function (DUF4430)
IIAPBPCI_01356 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IIAPBPCI_01357 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
IIAPBPCI_01358 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
IIAPBPCI_01359 2.6e-146 L Transposase
IIAPBPCI_01360 3.6e-70 L Transposase
IIAPBPCI_01361 6.3e-191 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
IIAPBPCI_01362 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IIAPBPCI_01363 3.2e-92 dps P Belongs to the Dps family
IIAPBPCI_01364 4.2e-92 dps P Belongs to the Dps family
IIAPBPCI_01365 4.4e-79 perR P Belongs to the Fur family
IIAPBPCI_01366 1.9e-27 yqgQ S protein conserved in bacteria
IIAPBPCI_01367 7.8e-177 glk 2.7.1.2 G Glucokinase
IIAPBPCI_01368 0.0 typA T GTP-binding protein TypA
IIAPBPCI_01370 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIAPBPCI_01371 3.9e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIAPBPCI_01372 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIAPBPCI_01373 2.3e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIAPBPCI_01374 2.7e-236 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIAPBPCI_01375 5.1e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IIAPBPCI_01376 1.4e-96 sepF D cell septum assembly
IIAPBPCI_01377 2e-34 yggT D integral membrane protein
IIAPBPCI_01378 8e-143 ylmH T S4 RNA-binding domain
IIAPBPCI_01379 3.3e-134 divIVA D Cell division protein DivIVA
IIAPBPCI_01380 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIAPBPCI_01381 7.9e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
IIAPBPCI_01382 2e-45 rpmE2 J 50S ribosomal protein L31
IIAPBPCI_01383 1e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIAPBPCI_01384 6.5e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
IIAPBPCI_01385 2.6e-154 gst O Glutathione S-transferase
IIAPBPCI_01386 6.7e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IIAPBPCI_01387 3.5e-111 tdk 2.7.1.21 F thymidine kinase
IIAPBPCI_01388 1.8e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIAPBPCI_01389 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIAPBPCI_01390 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIAPBPCI_01391 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIAPBPCI_01392 1e-176 ndpA S 37-kD nucleoid-associated bacterial protein
IIAPBPCI_01393 1.6e-106 pvaA M lytic transglycosylase activity
IIAPBPCI_01394 0.0 yfiB1 V abc transporter atp-binding protein
IIAPBPCI_01395 0.0 XK27_10035 V abc transporter atp-binding protein
IIAPBPCI_01396 1.2e-09 S D-Ala-teichoic acid biosynthesis protein
IIAPBPCI_01397 6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAPBPCI_01398 1.6e-235 dltB M Membrane protein involved in D-alanine export
IIAPBPCI_01399 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAPBPCI_01400 3.7e-227 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIAPBPCI_01401 4.9e-57 L Integrase core domain protein
IIAPBPCI_01402 4.2e-10 L transposase activity
IIAPBPCI_01403 3.6e-39 L Transposase
IIAPBPCI_01404 0.0 3.6.3.8 P cation transport ATPase
IIAPBPCI_01405 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
IIAPBPCI_01407 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IIAPBPCI_01408 1.1e-164 metF 1.5.1.20 C reductase
IIAPBPCI_01409 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IIAPBPCI_01410 1.1e-93 panT S ECF transporter, substrate-specific component
IIAPBPCI_01411 1.4e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIAPBPCI_01412 2.8e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
IIAPBPCI_01413 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IIAPBPCI_01414 1.2e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAPBPCI_01415 4.1e-43 T PhoQ Sensor
IIAPBPCI_01416 1.7e-120 T PhoQ Sensor
IIAPBPCI_01417 5.1e-122 L Transposase
IIAPBPCI_01418 1.2e-165 L integrase core domain
IIAPBPCI_01419 1.3e-29 rpsT J rRNA binding
IIAPBPCI_01420 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
IIAPBPCI_01421 3.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
IIAPBPCI_01422 2.3e-26 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IIAPBPCI_01423 3e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IIAPBPCI_01424 6.1e-94 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IIAPBPCI_01425 1.1e-10 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IIAPBPCI_01426 2.9e-30 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIAPBPCI_01427 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIAPBPCI_01428 4.7e-57 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IIAPBPCI_01429 1.6e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IIAPBPCI_01430 6.4e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IIAPBPCI_01431 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
IIAPBPCI_01432 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
IIAPBPCI_01433 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IIAPBPCI_01434 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IIAPBPCI_01435 3.1e-81 ypmB S Protein conserved in bacteria
IIAPBPCI_01436 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IIAPBPCI_01437 4.2e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IIAPBPCI_01438 2.5e-15
IIAPBPCI_01439 6.8e-54 L Transposase
IIAPBPCI_01440 2.7e-31 L Transposase
IIAPBPCI_01441 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
IIAPBPCI_01442 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IIAPBPCI_01443 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
IIAPBPCI_01444 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IIAPBPCI_01445 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IIAPBPCI_01446 6.5e-190 L Transposase
IIAPBPCI_01447 2.6e-55 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
IIAPBPCI_01448 2.3e-93 hsdM 2.1.1.72 V type I restriction-modification system
IIAPBPCI_01449 1.4e-151 glcU U Glucose uptake
IIAPBPCI_01450 1.1e-220 L Transposase
IIAPBPCI_01451 4.2e-18 D nuclear chromosome segregation
IIAPBPCI_01452 1.5e-135 yejC S cyclic nucleotide-binding protein
IIAPBPCI_01453 4.5e-163 rapZ S Displays ATPase and GTPase activities
IIAPBPCI_01454 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IIAPBPCI_01455 1.9e-161 whiA K May be required for sporulation
IIAPBPCI_01456 1.2e-103 pepD E Dipeptidase
IIAPBPCI_01457 2.6e-44 pepD E Dipeptidase
IIAPBPCI_01458 1.5e-75 tspO T TspO/MBR family
IIAPBPCI_01459 2e-59 S Uncharacterised lipoprotein family
IIAPBPCI_01460 1.2e-180 L Transposase
IIAPBPCI_01461 7.1e-28 L transposase activity
IIAPBPCI_01463 6.4e-50
IIAPBPCI_01465 2.1e-120 S Protein of unknown function (DUF2786)
IIAPBPCI_01467 4.2e-278 repE K Primase C terminal 1 (PriCT-1)
IIAPBPCI_01469 6.1e-15
IIAPBPCI_01470 3.8e-40
IIAPBPCI_01471 4.6e-34 S Thioredoxin
IIAPBPCI_01472 1.2e-14
IIAPBPCI_01475 3.7e-89
IIAPBPCI_01478 3.6e-20 S the current gene model (or a revised gene model) may contain a frame shift
IIAPBPCI_01479 1.7e-36 S the current gene model (or a revised gene model) may contain a frame shift
IIAPBPCI_01480 6.7e-142 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
IIAPBPCI_01481 1.6e-39
IIAPBPCI_01482 0.0 ruvB 3.6.4.12 L four-way junction helicase activity
IIAPBPCI_01483 7.5e-18
IIAPBPCI_01484 0.0 EL Toprim-like
IIAPBPCI_01486 0.0 topB 5.99.1.2 L Topoisomerase IA
IIAPBPCI_01487 0.0 clpB O Belongs to the ClpA ClpB family
IIAPBPCI_01488 2.9e-33
IIAPBPCI_01489 3.4e-197
IIAPBPCI_01490 1.8e-30 MU outer membrane autotransporter barrel domain protein
IIAPBPCI_01491 0.0 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IIAPBPCI_01492 1.2e-73 L single-stranded DNA binding
IIAPBPCI_01493 1.6e-189 nagZ 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
IIAPBPCI_01495 1.9e-13
IIAPBPCI_01496 0.0 U COG3505 Type IV secretory pathway, VirD4 components
IIAPBPCI_01497 2.8e-26
IIAPBPCI_01498 1.4e-218
IIAPBPCI_01499 7.5e-27 S BRCA1 C Terminus (BRCT) domain
IIAPBPCI_01500 1.3e-13 S Uncharacterized protein pXO2-11
IIAPBPCI_01501 3e-84
IIAPBPCI_01502 0.0 trsE S COG0433 Predicted ATPase
IIAPBPCI_01503 1.7e-22
IIAPBPCI_01504 1.2e-231 NU amidase activity
IIAPBPCI_01505 2.9e-57
IIAPBPCI_01506 4e-150 D plasmid maintenance
IIAPBPCI_01507 4.6e-18
IIAPBPCI_01508 4e-28 S Replication initiator protein A (RepA) N-terminus
IIAPBPCI_01509 5e-09
IIAPBPCI_01510 3e-259 S Uncharacterised protein family (UPF0236)
IIAPBPCI_01511 2.4e-57 pepD E Dipeptidase
IIAPBPCI_01512 1.2e-86 XK27_10720 D peptidase activity
IIAPBPCI_01513 3.6e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
IIAPBPCI_01514 1.7e-08
IIAPBPCI_01515 1.5e-170 yeiH S Membrane
IIAPBPCI_01516 1.6e-118 mur1 NU muramidase
IIAPBPCI_01517 4.2e-20 L transposase activity
IIAPBPCI_01518 4.5e-166 cpsY K Transcriptional regulator
IIAPBPCI_01519 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIAPBPCI_01520 6.1e-57 phnA P Alkylphosphonate utilization operon protein PhnA
IIAPBPCI_01521 5.3e-105 artQ P ABC transporter (Permease
IIAPBPCI_01522 9.8e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAPBPCI_01523 1.2e-157 aatB ET ABC transporter substrate-binding protein
IIAPBPCI_01524 2.1e-73 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIAPBPCI_01525 1.9e-110 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIAPBPCI_01526 2.1e-07
IIAPBPCI_01527 6.6e-62 adhP 1.1.1.1 C alcohol dehydrogenase
IIAPBPCI_01528 6.1e-112 adhP 1.1.1.1 C alcohol dehydrogenase
IIAPBPCI_01530 3e-21
IIAPBPCI_01531 0.0 res_1 3.1.21.5 S Type III restriction
IIAPBPCI_01532 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
IIAPBPCI_01533 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IIAPBPCI_01534 2e-126 gntR1 K transcriptional
IIAPBPCI_01535 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIAPBPCI_01536 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIAPBPCI_01537 3.1e-87 niaX
IIAPBPCI_01538 6e-91 niaR S small molecule binding protein (contains 3H domain)
IIAPBPCI_01539 8.1e-128 K DNA-binding helix-turn-helix protein
IIAPBPCI_01540 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIAPBPCI_01541 5.9e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIAPBPCI_01542 4e-85 GK ROK family
IIAPBPCI_01543 1.6e-70 GK ROK family
IIAPBPCI_01544 8.3e-159 dprA LU DNA protecting protein DprA
IIAPBPCI_01545 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIAPBPCI_01546 3.6e-154 S TraX protein
IIAPBPCI_01547 2.7e-120 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAPBPCI_01548 1.9e-248 T PhoQ Sensor
IIAPBPCI_01549 9.6e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IIAPBPCI_01550 6.5e-78 XK27_05470 E Methionine synthase
IIAPBPCI_01551 9.3e-36 XK27_05470 E Methionine synthase
IIAPBPCI_01552 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IIAPBPCI_01553 1.9e-46 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIAPBPCI_01554 6.8e-51 IQ Acetoin reductase
IIAPBPCI_01555 2.6e-45 IQ Acetoin reductase
IIAPBPCI_01557 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIAPBPCI_01561 1.1e-53 K peptidyl-tyrosine sulfation
IIAPBPCI_01562 1.6e-58 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IIAPBPCI_01563 2e-55 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IIAPBPCI_01566 1.1e-212 pqqE C radical SAM domain protein
IIAPBPCI_01567 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
IIAPBPCI_01568 6.6e-61 EGP Major facilitator Superfamily
IIAPBPCI_01569 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IIAPBPCI_01570 5.9e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IIAPBPCI_01571 1.8e-234 L Transposase
IIAPBPCI_01572 8.2e-118 V ABC transporter (Permease
IIAPBPCI_01573 3.4e-113 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IIAPBPCI_01574 1.6e-10
IIAPBPCI_01575 1.2e-97 K Transcriptional regulator, TetR family
IIAPBPCI_01576 1.3e-157 czcD P cation diffusion facilitator family transporter
IIAPBPCI_01577 2.3e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IIAPBPCI_01578 3.1e-195 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
IIAPBPCI_01579 2.3e-07 S Hydrolases of the alpha beta superfamily
IIAPBPCI_01580 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
IIAPBPCI_01581 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
IIAPBPCI_01584 2.6e-143 2.4.2.3 F Phosphorylase superfamily
IIAPBPCI_01585 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
IIAPBPCI_01586 6.1e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
IIAPBPCI_01587 2.3e-19 V drug transmembrane transporter activity
IIAPBPCI_01588 3.9e-15 dinF V Mate efflux family protein
IIAPBPCI_01590 3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IIAPBPCI_01592 6.1e-81 S TraX protein
IIAPBPCI_01593 6.5e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
IIAPBPCI_01594 4.8e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IIAPBPCI_01595 1.9e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IIAPBPCI_01596 9.1e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIAPBPCI_01597 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIAPBPCI_01598 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
IIAPBPCI_01599 9.7e-264 dtpT E transporter
IIAPBPCI_01600 5.6e-104 nylA 3.5.1.4 J Belongs to the amidase family
IIAPBPCI_01601 2.4e-61 yckB ET Belongs to the bacterial solute-binding protein 3 family
IIAPBPCI_01602 2.9e-58 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
IIAPBPCI_01603 5.5e-53 yecS P ABC transporter (Permease
IIAPBPCI_01605 2.6e-23 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IIAPBPCI_01606 2.5e-63 yfiF3 K sequence-specific DNA binding
IIAPBPCI_01607 5.5e-24 bglC K Transcriptional regulator
IIAPBPCI_01608 8.6e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIAPBPCI_01609 4e-240 agcS E (Alanine) symporter
IIAPBPCI_01610 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IIAPBPCI_01611 2.3e-240 metY 2.5.1.49 E o-acetylhomoserine
IIAPBPCI_01612 3.2e-133 S haloacid dehalogenase-like hydrolase
IIAPBPCI_01613 3.8e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IIAPBPCI_01614 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
IIAPBPCI_01615 5.7e-33 M1-755 P Hemerythrin HHE cation binding domain protein
IIAPBPCI_01616 2.4e-77 XK27_04775 S hemerythrin HHE cation binding domain
IIAPBPCI_01617 3.1e-69 XK27_04775 S hemerythrin HHE cation binding domain
IIAPBPCI_01618 4.4e-49 XK27_04775 S hemerythrin HHE cation binding domain
IIAPBPCI_01619 8.4e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIAPBPCI_01620 5.5e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IIAPBPCI_01621 5.7e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIAPBPCI_01622 6.7e-44 yktA S Belongs to the UPF0223 family
IIAPBPCI_01623 4.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IIAPBPCI_01624 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IIAPBPCI_01625 1.4e-156 pstS P phosphate
IIAPBPCI_01626 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
IIAPBPCI_01627 1.5e-155 pstA P phosphate transport system permease
IIAPBPCI_01628 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIAPBPCI_01629 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIAPBPCI_01630 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
IIAPBPCI_01631 0.0 pepN 3.4.11.2 E aminopeptidase
IIAPBPCI_01632 1e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IIAPBPCI_01633 4.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
IIAPBPCI_01636 3.7e-09
IIAPBPCI_01637 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IIAPBPCI_01638 1.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
IIAPBPCI_01639 1.2e-62 malR K Transcriptional regulator
IIAPBPCI_01640 3.7e-46 malR K Transcriptional regulator
IIAPBPCI_01641 4.2e-17 malX G ABC transporter
IIAPBPCI_01642 9.1e-168 malX G ABC transporter
IIAPBPCI_01643 1.1e-202 malF P ABC transporter (Permease
IIAPBPCI_01644 2.8e-48
IIAPBPCI_01645 1.2e-157 L Transposase
IIAPBPCI_01646 4.6e-25 tatA U protein secretion
IIAPBPCI_01647 4.4e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IIAPBPCI_01648 3e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
IIAPBPCI_01649 5.6e-233 ycdB P peroxidase
IIAPBPCI_01650 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
IIAPBPCI_01651 1.2e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAPBPCI_01652 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAPBPCI_01653 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAPBPCI_01654 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAPBPCI_01655 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAPBPCI_01656 1.6e-185 3.5.1.28 M GBS Bsp-like repeat
IIAPBPCI_01657 1.9e-65 3.2.1.17 M lysozyme activity
IIAPBPCI_01658 9.9e-12 3.5.1.28 NU amidase activity
IIAPBPCI_01659 0.0 lpdA 1.8.1.4 C Dehydrogenase
IIAPBPCI_01660 1.3e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIAPBPCI_01661 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIAPBPCI_01662 1.7e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IIAPBPCI_01663 0.0 S the current gene model (or a revised gene model) may contain a frame shift
IIAPBPCI_01664 1.8e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IIAPBPCI_01665 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIAPBPCI_01666 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIAPBPCI_01667 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IIAPBPCI_01668 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
IIAPBPCI_01669 4.1e-127 3.4.16.4 M Belongs to the peptidase S11 family
IIAPBPCI_01670 1.2e-157 rssA S Phospholipase, patatin family
IIAPBPCI_01671 1.8e-69 estA E GDSL-like protein
IIAPBPCI_01672 3.4e-29 estA E Lysophospholipase L1 and related esterases
IIAPBPCI_01673 7e-292 S unusual protein kinase
IIAPBPCI_01674 4.9e-39 S granule-associated protein
IIAPBPCI_01675 4.6e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIAPBPCI_01676 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIAPBPCI_01677 1.3e-199 S hmm pf01594
IIAPBPCI_01678 2.5e-101 G Belongs to the phosphoglycerate mutase family
IIAPBPCI_01679 3.7e-60 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
IIAPBPCI_01680 1.1e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IIAPBPCI_01681 2.2e-94 V VanZ like family
IIAPBPCI_01682 2.7e-39 L Helix-turn-helix domain of transposase family ISL3
IIAPBPCI_01683 3.6e-64 L Transposase
IIAPBPCI_01684 2.9e-24 L Transposase
IIAPBPCI_01685 4.2e-192 wbbI M transferase activity, transferring glycosyl groups
IIAPBPCI_01686 1e-212 glf 5.4.99.9 M UDP-galactopyranose mutase
IIAPBPCI_01687 5.4e-243 epsU S Polysaccharide biosynthesis protein
IIAPBPCI_01688 6.3e-173
IIAPBPCI_01689 7.1e-149 M Glycosyltransferase like family 2
IIAPBPCI_01690 8.6e-123 M Glycosyltransferase, group 2 family protein
IIAPBPCI_01692 4.6e-73 Z012_10770 M Domain of unknown function (DUF1919)
IIAPBPCI_01693 4.3e-206 wcoF M Glycosyltransferase, group 1 family protein
IIAPBPCI_01694 5e-218 rgpAc GT4 M group 1 family protein
IIAPBPCI_01695 1e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IIAPBPCI_01696 2.5e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
IIAPBPCI_01697 1.7e-109 cps4C M biosynthesis protein
IIAPBPCI_01698 1.9e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
IIAPBPCI_01699 2.1e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
IIAPBPCI_01700 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
IIAPBPCI_01701 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
IIAPBPCI_01702 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
IIAPBPCI_01703 9e-88 clcA_2 P chloride
IIAPBPCI_01704 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IIAPBPCI_01705 8.1e-41 S Protein of unknown function (DUF1697)
IIAPBPCI_01706 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IIAPBPCI_01707 5e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IIAPBPCI_01709 5.7e-08 V Glucan-binding protein C
IIAPBPCI_01710 2.7e-22 V Glucan-binding protein C
IIAPBPCI_01711 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
IIAPBPCI_01712 9e-275 pepV 3.5.1.18 E Dipeptidase
IIAPBPCI_01713 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IIAPBPCI_01714 2e-41 XK27_03610 K Gnat family
IIAPBPCI_01715 7.2e-83 L Transposase
IIAPBPCI_01716 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIAPBPCI_01717 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IIAPBPCI_01718 5.9e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIAPBPCI_01719 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IIAPBPCI_01720 2.8e-18 M LysM domain
IIAPBPCI_01721 1.2e-88 ebsA S Family of unknown function (DUF5322)
IIAPBPCI_01722 6.5e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IIAPBPCI_01723 6e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IIAPBPCI_01724 2.4e-223 G COG0457 FOG TPR repeat
IIAPBPCI_01725 8.1e-176 yubA S permease
IIAPBPCI_01726 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
IIAPBPCI_01727 5.2e-162 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IIAPBPCI_01728 5.5e-124 ftsE D cell division ATP-binding protein FtsE
IIAPBPCI_01729 1.8e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIAPBPCI_01730 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IIAPBPCI_01731 9.2e-183 yjjH S Calcineurin-like phosphoesterase
IIAPBPCI_01732 2e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IIAPBPCI_01733 0.0 pacL 3.6.3.8 P cation transport ATPase
IIAPBPCI_01734 3.4e-67 ywiB S Domain of unknown function (DUF1934)
IIAPBPCI_01735 2.4e-44 XK27_00115 2.3.1.128 K acetyltransferase
IIAPBPCI_01736 9.2e-147 yidA S hydrolases of the HAD superfamily
IIAPBPCI_01737 2.6e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
IIAPBPCI_01738 4.2e-34 F Protein of unknown function (DUF454)
IIAPBPCI_01739 3.9e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
IIAPBPCI_01740 5.8e-247 vicK 2.7.13.3 T Histidine kinase
IIAPBPCI_01741 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAPBPCI_01742 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAPBPCI_01743 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IIAPBPCI_01744 8e-115 gltJ P ABC transporter (Permease
IIAPBPCI_01745 3.8e-111 tcyB_2 P ABC transporter (permease)
IIAPBPCI_01746 7e-124 endA F DNA RNA non-specific endonuclease
IIAPBPCI_01747 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
IIAPBPCI_01748 1.1e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIAPBPCI_01750 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIAPBPCI_01751 1.3e-36 5.1.3.2 GM Psort location CytoplasmicMembrane, score
IIAPBPCI_01752 6e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIAPBPCI_01753 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIAPBPCI_01754 7.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIAPBPCI_01755 2.7e-88 ytsP 1.8.4.14 T GAF domain-containing protein
IIAPBPCI_01756 3e-162 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIAPBPCI_01757 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
IIAPBPCI_01759 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIAPBPCI_01760 2.1e-219 XK27_05110 P chloride
IIAPBPCI_01761 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
IIAPBPCI_01762 1.7e-282 clcA P Chloride transporter, ClC family
IIAPBPCI_01763 1e-75 fld C Flavodoxin
IIAPBPCI_01764 3.3e-14 XK27_08880
IIAPBPCI_01765 3e-125 XK27_08875 O Zinc-dependent metalloprotease
IIAPBPCI_01766 1.1e-149 estA CE1 S Putative esterase
IIAPBPCI_01767 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIAPBPCI_01768 4.4e-135 XK27_08845 S abc transporter atp-binding protein
IIAPBPCI_01769 2e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
IIAPBPCI_01770 5.4e-173 XK27_08835 S ABC transporter substrate binding protein
IIAPBPCI_01771 3.2e-17 S Domain of unknown function (DUF4649)
IIAPBPCI_01772 3.7e-31 Q the current gene model (or a revised gene model) may contain a frame shift
IIAPBPCI_01773 6.3e-28 Q the current gene model (or a revised gene model) may contain a frame shift
IIAPBPCI_01776 3.1e-107 L Transposase
IIAPBPCI_01777 9.8e-112 L Transposase
IIAPBPCI_01778 8.2e-274 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IIAPBPCI_01779 2.1e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IIAPBPCI_01780 0.0 dnaE 2.7.7.7 L DNA polymerase
IIAPBPCI_01781 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
IIAPBPCI_01782 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIAPBPCI_01783 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIAPBPCI_01784 2.5e-43 ysdA L Membrane
IIAPBPCI_01785 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IIAPBPCI_01786 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IIAPBPCI_01787 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIAPBPCI_01788 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IIAPBPCI_01790 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIAPBPCI_01791 1.7e-94 ypmS S Protein conserved in bacteria
IIAPBPCI_01792 6.7e-87 ypmR E lipolytic protein G-D-S-L family
IIAPBPCI_01793 3.8e-45 ypmR E COG2755 Lysophospholipase L1 and related esterases
IIAPBPCI_01794 3.3e-147 DegV S DegV family
IIAPBPCI_01795 2.9e-304 recN L May be involved in recombinational repair of damaged DNA
IIAPBPCI_01796 3.7e-73 argR K Regulates arginine biosynthesis genes
IIAPBPCI_01797 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IIAPBPCI_01798 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IIAPBPCI_01799 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
IIAPBPCI_01800 2.6e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIAPBPCI_01801 2.5e-07 KT response to antibiotic
IIAPBPCI_01803 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IIAPBPCI_01804 1.5e-124 dnaD
IIAPBPCI_01805 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IIAPBPCI_01806 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIAPBPCI_01807 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
IIAPBPCI_01808 1.5e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIAPBPCI_01809 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIAPBPCI_01810 3.9e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IIAPBPCI_01811 2.7e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIAPBPCI_01812 7.3e-232 rodA D Belongs to the SEDS family
IIAPBPCI_01813 2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IIAPBPCI_01814 8e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IIAPBPCI_01815 8.9e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IIAPBPCI_01816 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IIAPBPCI_01817 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IIAPBPCI_01818 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IIAPBPCI_01819 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IIAPBPCI_01820 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IIAPBPCI_01821 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IIAPBPCI_01822 8.2e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IIAPBPCI_01824 1.3e-31 L Integrase core domain protein
IIAPBPCI_01825 4.5e-09 L transposition
IIAPBPCI_01826 7.4e-83 L Transposase
IIAPBPCI_01827 2e-31 XK27_08085
IIAPBPCI_01828 8.4e-88 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IIAPBPCI_01829 7.9e-10 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IIAPBPCI_01830 5.8e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IIAPBPCI_01831 5.8e-120 ylfI S tigr01906
IIAPBPCI_01832 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIAPBPCI_01833 5.7e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
IIAPBPCI_01834 6.9e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
IIAPBPCI_01835 1.8e-220 L Transposase
IIAPBPCI_01838 5.6e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIAPBPCI_01839 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IIAPBPCI_01840 5.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IIAPBPCI_01841 1.7e-204 yurR 1.4.5.1 E oxidoreductase
IIAPBPCI_01842 1.6e-101 zupT P Mediates zinc uptake. May also transport other divalent cations
IIAPBPCI_01843 7e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
IIAPBPCI_01844 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIAPBPCI_01845 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
IIAPBPCI_01846 1.3e-70 gtrA S GtrA-like protein
IIAPBPCI_01847 8.2e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIAPBPCI_01848 4.3e-167 ybbR S Protein conserved in bacteria
IIAPBPCI_01849 2.8e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIAPBPCI_01850 1.8e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
IIAPBPCI_01851 3.3e-149 cobQ S glutamine amidotransferase
IIAPBPCI_01852 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIAPBPCI_01853 3.1e-130 pip 1.11.1.10 S Alpha beta hydrolase
IIAPBPCI_01855 0.0 uup S abc transporter atp-binding protein
IIAPBPCI_01856 6.2e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IIAPBPCI_01857 1.5e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
IIAPBPCI_01858 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IIAPBPCI_01859 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
IIAPBPCI_01860 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIAPBPCI_01861 7.9e-39 ptsH G phosphocarrier protein Hpr
IIAPBPCI_01862 8.2e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
IIAPBPCI_01863 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
IIAPBPCI_01864 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IIAPBPCI_01865 8.5e-34 nrdH O Glutaredoxin
IIAPBPCI_01866 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIAPBPCI_01867 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIAPBPCI_01869 4.2e-71 L Transposase (IS116 IS110 IS902 family)
IIAPBPCI_01870 8.8e-60 L Transposase (IS116 IS110 IS902 family)
IIAPBPCI_01871 5.3e-165 ypuA S secreted protein
IIAPBPCI_01872 1.5e-52 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
IIAPBPCI_01873 1.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
IIAPBPCI_01874 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIAPBPCI_01875 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IIAPBPCI_01876 8.3e-257 noxE P NADH oxidase
IIAPBPCI_01877 3.6e-293 yfmM S abc transporter atp-binding protein
IIAPBPCI_01878 4.8e-59 XK27_01265 S ECF-type riboflavin transporter, S component
IIAPBPCI_01879 8.1e-182 L Transposase
IIAPBPCI_01880 1.5e-10 XK27_01265 S ECF-type riboflavin transporter, S component
IIAPBPCI_01881 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IIAPBPCI_01882 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IIAPBPCI_01883 2e-86 S ECF-type riboflavin transporter, S component
IIAPBPCI_01885 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIAPBPCI_01886 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
IIAPBPCI_01888 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIAPBPCI_01889 3.8e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIAPBPCI_01890 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIAPBPCI_01891 0.0 smc D Required for chromosome condensation and partitioning
IIAPBPCI_01892 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIAPBPCI_01893 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIAPBPCI_01894 3.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IIAPBPCI_01895 1.7e-78 alkD L Dna alkylation repair
IIAPBPCI_01896 2.8e-93 pat 2.3.1.183 M acetyltransferase
IIAPBPCI_01897 1.6e-11 L Transposase
IIAPBPCI_01898 6.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIAPBPCI_01899 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIAPBPCI_01900 3.9e-37 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IIAPBPCI_01901 1.5e-21 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IIAPBPCI_01902 4.4e-88 proW P Binding-protein-dependent transport system inner membrane component
IIAPBPCI_01903 1.6e-137 proV E abc transporter atp-binding protein
IIAPBPCI_01904 3.8e-165 proX M ABC transporter, substrate-binding protein, QAT family
IIAPBPCI_01905 4.3e-102 proWZ P ABC transporter (Permease
IIAPBPCI_01906 2.5e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
IIAPBPCI_01907 1.6e-205 S Protein of unknown function (DUF917)
IIAPBPCI_01908 2.5e-308 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IIAPBPCI_01909 4.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
IIAPBPCI_01910 1.3e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIAPBPCI_01911 4.5e-189 desK 2.7.13.3 T Histidine kinase
IIAPBPCI_01912 1.1e-130 yvfS V ABC-2 type transporter
IIAPBPCI_01913 2.2e-157 XK27_09825 V abc transporter atp-binding protein
IIAPBPCI_01916 2.5e-164 yocS S Transporter
IIAPBPCI_01917 1.4e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
IIAPBPCI_01918 2.6e-35 XK27_05000 S metal cluster binding
IIAPBPCI_01919 0.0 V ABC transporter (permease)
IIAPBPCI_01920 2.4e-133 macB2 V ABC transporter, ATP-binding protein
IIAPBPCI_01921 3.1e-165 T Histidine kinase
IIAPBPCI_01922 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAPBPCI_01923 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIAPBPCI_01924 8.4e-141 pbuX F xanthine permease
IIAPBPCI_01925 4.4e-59 pbuX F xanthine permease
IIAPBPCI_01926 1.3e-246 norM V Multidrug efflux pump
IIAPBPCI_01927 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIAPBPCI_01928 2.6e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
IIAPBPCI_01929 1.1e-197 pcaB 4.3.2.2 F Adenylosuccinate lyase
IIAPBPCI_01930 2.8e-92 yxeO 3.6.3.21 E abc transporter atp-binding protein
IIAPBPCI_01931 9.8e-65 yxeN U ABC transporter, permease protein
IIAPBPCI_01932 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
IIAPBPCI_01933 2.3e-115 yxeQ S MmgE/PrpD family
IIAPBPCI_01934 6e-147 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IIAPBPCI_01935 1.9e-102 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
IIAPBPCI_01936 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
IIAPBPCI_01937 2.3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIAPBPCI_01938 1.5e-234 brnQ E Component of the transport system for branched-chain amino acids
IIAPBPCI_01939 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIAPBPCI_01940 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIAPBPCI_01941 4.8e-25 csbD K CsbD-like
IIAPBPCI_01942 1.1e-227 yfnA E amino acid
IIAPBPCI_01943 4e-69 S dextransucrase activity
IIAPBPCI_01944 6.3e-14 S dextransucrase activity
IIAPBPCI_01945 8.8e-39 S dextransucrase activity
IIAPBPCI_01946 1.1e-139 S dextransucrase activity
IIAPBPCI_01947 1.6e-21 L Integrase core domain protein
IIAPBPCI_01950 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
IIAPBPCI_01951 6.7e-114 yxeN P ABC transporter, permease protein
IIAPBPCI_01952 6.1e-107 ytmL P ABC transporter (Permease
IIAPBPCI_01953 2.4e-161 ET ABC transporter substrate-binding protein
IIAPBPCI_01954 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
IIAPBPCI_01955 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IIAPBPCI_01956 2.4e-40 S Sugar efflux transporter for intercellular exchange
IIAPBPCI_01957 5.9e-23 P FtsX-like permease family
IIAPBPCI_01958 3.2e-91 V abc transporter atp-binding protein
IIAPBPCI_01959 3.9e-82 K WHG domain
IIAPBPCI_01960 9.4e-68 ydhF S Aldo keto reductase
IIAPBPCI_01961 2.1e-71 ydhF S Aldo keto reductase
IIAPBPCI_01963 5.7e-109 XK27_02070 S nitroreductase
IIAPBPCI_01964 5.3e-150 1.13.11.2 S glyoxalase
IIAPBPCI_01965 3.8e-102 L Transposase
IIAPBPCI_01966 2.3e-119 L Transposase
IIAPBPCI_01967 4.7e-76 ywnA K Transcriptional regulator
IIAPBPCI_01968 1.6e-157 E Alpha/beta hydrolase of unknown function (DUF915)
IIAPBPCI_01969 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIAPBPCI_01970 2.2e-111 drgA C Nitroreductase
IIAPBPCI_01971 8.2e-68 yoaK S Protein of unknown function (DUF1275)
IIAPBPCI_01972 8.1e-27 yoaK S Protein of unknown function (DUF1275)
IIAPBPCI_01973 8.4e-159 yvgN C reductase
IIAPBPCI_01974 2.6e-180 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIAPBPCI_01975 3e-284 XK27_07020 S Belongs to the UPF0371 family
IIAPBPCI_01977 4.8e-55 K response regulator
IIAPBPCI_01978 2.7e-71 S Signal peptide protein, YSIRK family
IIAPBPCI_01980 3.2e-59
IIAPBPCI_01981 4.2e-264 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIAPBPCI_01982 8.5e-117
IIAPBPCI_01983 9.4e-11
IIAPBPCI_01985 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IIAPBPCI_01986 1.1e-74 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
IIAPBPCI_01987 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
IIAPBPCI_01988 0.0 M family 8
IIAPBPCI_01989 1.5e-37 L transposase activity
IIAPBPCI_01990 1.5e-39 L transposition
IIAPBPCI_01991 1.5e-21 L Transposase and inactivated derivatives
IIAPBPCI_01992 9e-44 L COG2963 Transposase and inactivated derivatives
IIAPBPCI_01993 8.5e-09
IIAPBPCI_01994 3.3e-30 S Antidote-toxin recognition MazE, bacterial antitoxin
IIAPBPCI_01995 1e-69 doc S Prophage maintenance system killer protein
IIAPBPCI_01996 1.3e-232 L Transposase
IIAPBPCI_01997 2.2e-17
IIAPBPCI_01998 1.5e-39 L transposition
IIAPBPCI_01999 5.9e-62 L Transposase and inactivated derivatives
IIAPBPCI_02000 3.1e-44 L COG2963 Transposase and inactivated derivatives
IIAPBPCI_02001 1e-31
IIAPBPCI_02002 0.0 sbcC L ATPase involved in DNA repair
IIAPBPCI_02003 7.6e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIAPBPCI_02004 0.0 lacL 3.2.1.23 G -beta-galactosidase
IIAPBPCI_02005 0.0 lacS G transporter
IIAPBPCI_02006 8.7e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IIAPBPCI_02007 4.3e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIAPBPCI_02008 2.8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IIAPBPCI_02009 2e-219 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIAPBPCI_02010 1.7e-21 galR K Transcriptional regulator
IIAPBPCI_02011 2.3e-150 galR K Transcriptional regulator
IIAPBPCI_02012 1.2e-08 L Integrase core domain protein
IIAPBPCI_02013 6.7e-24 L transposition
IIAPBPCI_02014 3.6e-258 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IIAPBPCI_02015 3.6e-100 V abc transporter atp-binding protein
IIAPBPCI_02016 2.1e-39 V (ABC) transporter
IIAPBPCI_02017 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IIAPBPCI_02019 1.4e-273 S Protein of unknown function (DUF3114)
IIAPBPCI_02020 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
IIAPBPCI_02021 1.1e-196 V (ABC) transporter
IIAPBPCI_02022 1.2e-157 C Arylsulfatase regulator (Fe-S oxidoreductase)
IIAPBPCI_02023 5.9e-219 L Transposase
IIAPBPCI_02024 2e-11 C Arylsulfatase regulator (Fe-S oxidoreductase)
IIAPBPCI_02025 1.6e-112 K sequence-specific DNA binding
IIAPBPCI_02026 4.6e-18 L COG2801 Transposase and inactivated derivatives
IIAPBPCI_02027 3e-25 L COG2801 Transposase and inactivated derivatives
IIAPBPCI_02028 3.3e-68 L transposition
IIAPBPCI_02029 1.5e-37 L transposase activity
IIAPBPCI_02030 5.9e-25 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IIAPBPCI_02031 2.1e-82 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAPBPCI_02032 6.6e-84 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAPBPCI_02033 3.6e-117 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAPBPCI_02034 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IIAPBPCI_02035 5e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IIAPBPCI_02036 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IIAPBPCI_02037 1.3e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIAPBPCI_02040 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIAPBPCI_02041 3.8e-174 vraS 2.7.13.3 T Histidine kinase
IIAPBPCI_02042 9.1e-119 yvqF KT membrane
IIAPBPCI_02043 5.3e-307 prkC 2.7.11.1 KLT serine threonine protein kinase
IIAPBPCI_02044 2.9e-131 stp 3.1.3.16 T phosphatase
IIAPBPCI_02045 2.2e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIAPBPCI_02046 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIAPBPCI_02047 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIAPBPCI_02048 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
IIAPBPCI_02049 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IIAPBPCI_02050 6.7e-214 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIAPBPCI_02051 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
IIAPBPCI_02052 2.1e-148 supH S overlaps another CDS with the same product name
IIAPBPCI_02053 8.6e-63 yvoA_1 K Transcriptional
IIAPBPCI_02054 9.8e-121 skfE V abc transporter atp-binding protein
IIAPBPCI_02055 5.6e-133 V ATPase activity
IIAPBPCI_02056 1.2e-171 oppF P Belongs to the ABC transporter superfamily
IIAPBPCI_02057 1.4e-203 oppD P Belongs to the ABC transporter superfamily
IIAPBPCI_02058 3.1e-167 amiD P ABC transporter (Permease
IIAPBPCI_02059 1.1e-270 amiC P ABC transporter (Permease
IIAPBPCI_02060 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IIAPBPCI_02061 1.2e-24 oppF P Belongs to the ABC transporter superfamily
IIAPBPCI_02062 1.1e-44 oppF P Belongs to the ABC transporter superfamily
IIAPBPCI_02063 1.4e-40 tatD L Hydrolase, tatd
IIAPBPCI_02064 9.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
IIAPBPCI_02065 3.6e-95 L PFAM Integrase catalytic region
IIAPBPCI_02066 4.9e-18 L Transposase
IIAPBPCI_02067 6.1e-37 L Transposase
IIAPBPCI_02068 5.9e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IIAPBPCI_02069 1.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IIAPBPCI_02070 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIAPBPCI_02071 1.4e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
IIAPBPCI_02072 1.5e-103 yjbK S Adenylate cyclase
IIAPBPCI_02073 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIAPBPCI_02074 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
IIAPBPCI_02075 2e-58 XK27_04120 S Putative amino acid metabolism
IIAPBPCI_02076 4.7e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIAPBPCI_02077 2.7e-123 puuD T peptidase C26
IIAPBPCI_02078 1.2e-115 radC E Belongs to the UPF0758 family
IIAPBPCI_02079 1.7e-268 M Psort location CytoplasmicMembrane, score
IIAPBPCI_02080 0.0 rgpF M Rhamnan synthesis protein F
IIAPBPCI_02081 4.5e-305 GT4 M transferase activity, transferring glycosyl groups
IIAPBPCI_02082 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IIAPBPCI_02083 1.8e-142 rgpC GM Transport permease protein
IIAPBPCI_02084 6.4e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
IIAPBPCI_02085 2.3e-228 rgpA GT4 M Domain of unknown function (DUF1972)
IIAPBPCI_02086 2.4e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
IIAPBPCI_02087 4.6e-42 S Uncharacterized conserved protein (DUF2304)
IIAPBPCI_02088 6.9e-130 arnC M group 2 family protein
IIAPBPCI_02089 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
IIAPBPCI_02090 6e-185 S Glycosyltransferase like family 2
IIAPBPCI_02091 8.2e-219 amrA S membrane protein involved in the export of O-antigen and teichoic acid
IIAPBPCI_02092 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIAPBPCI_02093 1.9e-245
IIAPBPCI_02094 9.8e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IIAPBPCI_02095 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
IIAPBPCI_02096 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIAPBPCI_02097 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIAPBPCI_02098 1.5e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IIAPBPCI_02099 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IIAPBPCI_02100 4.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
IIAPBPCI_02101 1.7e-199 arcT 2.6.1.1 E Aminotransferase
IIAPBPCI_02102 8.8e-134 ET ABC transporter
IIAPBPCI_02103 1.7e-140 ET Belongs to the bacterial solute-binding protein 3 family
IIAPBPCI_02104 2.9e-84 mutT 3.6.1.55 F Nudix family
IIAPBPCI_02105 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIAPBPCI_02107 4.3e-82 S CAAX amino terminal protease family protein
IIAPBPCI_02108 2.4e-33 S CAAX amino terminal protease family protein
IIAPBPCI_02109 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
IIAPBPCI_02110 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAPBPCI_02111 1.1e-16 XK27_00735
IIAPBPCI_02112 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIAPBPCI_02113 6.4e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIAPBPCI_02116 1.6e-64 paaI Q protein possibly involved in aromatic compounds catabolism
IIAPBPCI_02117 3.9e-50 ycaO O OsmC-like protein
IIAPBPCI_02119 3.8e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
IIAPBPCI_02121 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
IIAPBPCI_02122 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAPBPCI_02123 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAPBPCI_02124 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IIAPBPCI_02125 4.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
IIAPBPCI_02126 6.2e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIAPBPCI_02127 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIAPBPCI_02128 1.6e-97 3.1.3.18 S IA, variant 1
IIAPBPCI_02129 2.2e-117 lrgB M effector of murein hydrolase
IIAPBPCI_02130 7.7e-56 lrgA S Effector of murein hydrolase LrgA
IIAPBPCI_02132 3.2e-59 arsC 1.20.4.1 P Belongs to the ArsC family
IIAPBPCI_02133 5.3e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
IIAPBPCI_02134 1.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAPBPCI_02135 1.3e-104 wecD M Acetyltransferase (GNAT) domain
IIAPBPCI_02136 1.9e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IIAPBPCI_02137 4e-50 GK ROK family
IIAPBPCI_02138 4.1e-54 GK ROK family
IIAPBPCI_02139 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
IIAPBPCI_02140 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
IIAPBPCI_02141 1.7e-36 XK27_08050 O HflC and HflK could regulate a protease
IIAPBPCI_02142 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
IIAPBPCI_02143 2.3e-206 potD P spermidine putrescine ABC transporter
IIAPBPCI_02144 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
IIAPBPCI_02145 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
IIAPBPCI_02146 2.8e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IIAPBPCI_02147 7.8e-171 murB 1.3.1.98 M cell wall formation
IIAPBPCI_02148 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IIAPBPCI_02149 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IIAPBPCI_02150 3e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
IIAPBPCI_02151 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IIAPBPCI_02152 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
IIAPBPCI_02153 0.0 ydaO E amino acid
IIAPBPCI_02154 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IIAPBPCI_02155 4.1e-37 ylqC L Belongs to the UPF0109 family
IIAPBPCI_02156 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IIAPBPCI_02157 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
IIAPBPCI_02158 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
IIAPBPCI_02159 2.1e-74 S QueT transporter
IIAPBPCI_02160 1.7e-119 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
IIAPBPCI_02161 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IIAPBPCI_02162 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIAPBPCI_02163 1.3e-85 ccl S cog cog4708
IIAPBPCI_02164 2.4e-159 rbn E Belongs to the UPF0761 family
IIAPBPCI_02165 7.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IIAPBPCI_02166 2.8e-230 ytoI K transcriptional regulator containing CBS domains
IIAPBPCI_02167 1.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
IIAPBPCI_02168 2.5e-231 L Transposase
IIAPBPCI_02169 1.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIAPBPCI_02170 0.0 comEC S Competence protein ComEC
IIAPBPCI_02171 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IIAPBPCI_02172 1.7e-142 plsC 2.3.1.51 I Acyltransferase
IIAPBPCI_02173 1.8e-140 nodB3 G deacetylase
IIAPBPCI_02174 7.1e-141 yabB 2.1.1.223 L Methyltransferase
IIAPBPCI_02175 1e-41 yazA L endonuclease containing a URI domain
IIAPBPCI_02176 6.9e-223 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIAPBPCI_02177 1.5e-153 corA P CorA-like protein
IIAPBPCI_02178 2.5e-62 yjqA S Bacterial PH domain
IIAPBPCI_02179 2.3e-99 thiT S Thiamine transporter
IIAPBPCI_02180 2.1e-230 L Transposase
IIAPBPCI_02181 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IIAPBPCI_02182 7.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
IIAPBPCI_02183 1.7e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIAPBPCI_02187 1.1e-155 cjaA ET ABC transporter substrate-binding protein
IIAPBPCI_02188 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAPBPCI_02189 3e-106 P ABC transporter (Permease
IIAPBPCI_02190 3.9e-114 papP P ABC transporter (Permease
IIAPBPCI_02191 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IIAPBPCI_02192 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
IIAPBPCI_02193 0.0 copA 3.6.3.54 P P-type ATPase
IIAPBPCI_02194 2.7e-73 copY K Copper transport repressor, CopY TcrY family
IIAPBPCI_02195 6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IIAPBPCI_02196 3.8e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IIAPBPCI_02197 5.5e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
IIAPBPCI_02198 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IIAPBPCI_02199 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IIAPBPCI_02200 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
IIAPBPCI_02201 2e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IIAPBPCI_02202 1.8e-41 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
IIAPBPCI_02203 2.7e-55
IIAPBPCI_02204 0.0 ctpE P E1-E2 ATPase
IIAPBPCI_02205 1.6e-27
IIAPBPCI_02206 1.7e-67 L COG2801 Transposase and inactivated derivatives
IIAPBPCI_02207 1.5e-101 yiiE S protein homotetramerization
IIAPBPCI_02209 8.2e-27 S Membrane
IIAPBPCI_02210 3.3e-31
IIAPBPCI_02211 4.5e-39
IIAPBPCI_02212 9.7e-22 S Small integral membrane protein
IIAPBPCI_02213 9e-77 M Protein conserved in bacteria
IIAPBPCI_02214 1e-09 K CsbD-like
IIAPBPCI_02215 6.7e-125 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIAPBPCI_02216 1.4e-135 HJ the current gene model (or a revised gene model) may contain a frame shift
IIAPBPCI_02217 6.8e-195 L Transposase
IIAPBPCI_02218 9.9e-29 L Transposase
IIAPBPCI_02219 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIAPBPCI_02220 5.1e-47 L transposase activity
IIAPBPCI_02221 6e-121 K transcriptional regulator, MerR family
IIAPBPCI_02222 1.3e-102 dnaQ 2.7.7.7 L DNA polymerase III
IIAPBPCI_02223 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
IIAPBPCI_02224 4.8e-63 XK27_02560 S cog cog2151
IIAPBPCI_02225 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IIAPBPCI_02226 3.8e-226 ytfP S Flavoprotein
IIAPBPCI_02228 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIAPBPCI_02229 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
IIAPBPCI_02230 4.3e-181 ecsB U ABC transporter
IIAPBPCI_02231 1.1e-130 ecsA V abc transporter atp-binding protein
IIAPBPCI_02232 1.1e-69 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IIAPBPCI_02233 1.9e-09
IIAPBPCI_02235 1.1e-19
IIAPBPCI_02236 6.3e-07
IIAPBPCI_02237 1.5e-222 L Transposase
IIAPBPCI_02238 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
IIAPBPCI_02239 1.9e-200 ylbM S Belongs to the UPF0348 family
IIAPBPCI_02240 2e-140 yqeM Q Methyltransferase domain protein
IIAPBPCI_02241 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIAPBPCI_02242 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IIAPBPCI_02243 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIAPBPCI_02244 3.5e-49 yhbY J RNA-binding protein
IIAPBPCI_02245 7.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IIAPBPCI_02246 1.8e-98 yqeG S hydrolase of the HAD superfamily
IIAPBPCI_02247 4.7e-62 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIAPBPCI_02248 4.5e-80 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIAPBPCI_02249 2.1e-64
IIAPBPCI_02250 5.1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIAPBPCI_02251 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIAPBPCI_02252 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIAPBPCI_02253 1.5e-258 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIAPBPCI_02254 3.7e-60 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIAPBPCI_02255 4.1e-122 hlpA M Belongs to the NlpA lipoprotein family
IIAPBPCI_02256 9.8e-100 pncA Q isochorismatase
IIAPBPCI_02257 2.8e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IIAPBPCI_02258 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
IIAPBPCI_02259 6.9e-75 XK27_03180 T universal stress protein
IIAPBPCI_02261 2.7e-151 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIAPBPCI_02262 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
IIAPBPCI_02263 3.9e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
IIAPBPCI_02264 0.0 yjcE P NhaP-type Na H and K H antiporters
IIAPBPCI_02266 2e-97 ytqB 2.1.1.176 J (SAM)-dependent
IIAPBPCI_02267 3.3e-180 yhcC S radical SAM protein
IIAPBPCI_02268 7.8e-194 ylbL T Belongs to the peptidase S16 family
IIAPBPCI_02269 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIAPBPCI_02270 4.3e-92 rsmD 2.1.1.171 L Methyltransferase
IIAPBPCI_02271 5.5e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIAPBPCI_02272 1.1e-09 S Protein of unknown function (DUF4059)
IIAPBPCI_02273 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
IIAPBPCI_02274 2.3e-162 yxeN P ABC transporter (Permease
IIAPBPCI_02275 4.8e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IIAPBPCI_02277 8.8e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIAPBPCI_02278 0.0 pflB 2.3.1.54 C formate acetyltransferase'
IIAPBPCI_02279 7.2e-43 cah 4.2.1.1 P carbonic anhydrase
IIAPBPCI_02280 5.8e-39 cah 4.2.1.1 P carbonic anhydrase
IIAPBPCI_02281 1e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIAPBPCI_02282 1.6e-09 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
IIAPBPCI_02283 3.9e-42 D nuclear chromosome segregation
IIAPBPCI_02284 1e-31 D nuclear chromosome segregation
IIAPBPCI_02285 1.2e-32 L DNA integration
IIAPBPCI_02286 4.8e-58 L Phage integrase family
IIAPBPCI_02287 7.6e-118 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
IIAPBPCI_02288 9.9e-79 ybbM S transport system, permease component
IIAPBPCI_02289 3e-116 ybbL S abc transporter atp-binding protein
IIAPBPCI_02290 3.1e-31
IIAPBPCI_02291 3.8e-184 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
IIAPBPCI_02292 2.8e-137 cppA E CppA N-terminal
IIAPBPCI_02293 4.8e-108 L Transposase
IIAPBPCI_02294 9.8e-112 L Helix-turn-helix domain of transposase family ISL3
IIAPBPCI_02295 5.1e-21 L overlaps another CDS with the same product name
IIAPBPCI_02296 1.7e-44 K helix_turn_helix, Arsenical Resistance Operon Repressor
IIAPBPCI_02297 6.3e-160 yrdR EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIAPBPCI_02298 1.2e-71 2.7.7.12 C Domain of unknown function (DUF4931)
IIAPBPCI_02299 6.8e-153 S metal-dependent hydrolase with the TIM-barrel fold
IIAPBPCI_02300 7.7e-123 dlpA H Methyltransferase
IIAPBPCI_02301 4e-209 dlpA 1.1.1.85 CE Tartrate dehydrogenase
IIAPBPCI_02303 1.3e-160 4.1.3.39 E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)