ORF_ID e_value Gene_name EC_number CAZy COGs Description
HLLCKODE_00001 3.9e-67 ytxH S General stress protein
HLLCKODE_00002 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLLCKODE_00003 5.8e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLLCKODE_00004 1.6e-166 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLLCKODE_00005 2.2e-41 pspC KT PspC domain
HLLCKODE_00006 0.0 yhgF K Transcriptional accessory protein
HLLCKODE_00008 3.9e-154 XK27_03015 S permease
HLLCKODE_00009 8.4e-148 ycgQ S TIGR03943 family
HLLCKODE_00010 5.7e-276 sulP P Sulfate permease and related transporters (MFS superfamily)
HLLCKODE_00011 7.6e-101
HLLCKODE_00012 1.3e-114 estA E GDSL-like Lipase/Acylhydrolase
HLLCKODE_00013 4.1e-91 S CAAX protease self-immunity
HLLCKODE_00014 8.8e-49
HLLCKODE_00016 1.7e-63 yqeB S Pyrimidine dimer DNA glycosylase
HLLCKODE_00017 3.7e-61 S Protein of unknown function (DUF1722)
HLLCKODE_00018 2.6e-20 M Bacterial lipoprotein
HLLCKODE_00019 2.3e-11
HLLCKODE_00020 6.8e-128 V CAAX protease self-immunity
HLLCKODE_00021 7.9e-46
HLLCKODE_00022 3.4e-74 K TetR family transcriptional regulator
HLLCKODE_00023 1.2e-79 Q Methyltransferase domain
HLLCKODE_00024 4.2e-143 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLLCKODE_00025 1.3e-174 acoB C dehydrogenase E1 component
HLLCKODE_00026 3.6e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
HLLCKODE_00027 2.1e-172 pdhD 1.8.1.4 C Dehydrogenase
HLLCKODE_00028 7.8e-10 S CsbD-like
HLLCKODE_00029 5.5e-31 S Membrane
HLLCKODE_00030 1.4e-171 S Domain of unknown function (DUF389)
HLLCKODE_00031 2.8e-157 yegS 2.7.1.107 I Diacylglycerol kinase
HLLCKODE_00032 2.7e-123 ybbA S Putative esterase
HLLCKODE_00033 8.5e-174 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HLLCKODE_00034 4.6e-132 fecE 3.6.3.34 HP ABC transporter
HLLCKODE_00035 2.2e-156 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLCKODE_00036 7.7e-116 V CAAX protease self-immunity
HLLCKODE_00037 1.5e-147 S Domain of unknown function (DUF4300)
HLLCKODE_00038 6.3e-91 tetR K transcriptional regulator
HLLCKODE_00039 4.2e-253 norB P Major facilitator superfamily
HLLCKODE_00040 5.4e-21 S Domain of unknown function (DUF4767)
HLLCKODE_00042 8.6e-108 cutC P Participates in the control of copper homeostasis
HLLCKODE_00043 1e-99 ypgQ F HD superfamily hydrolase
HLLCKODE_00044 2.2e-94 XK27_08140 K Bacterial regulatory proteins, tetR family
HLLCKODE_00045 2.1e-149 yitS S EDD domain protein, DegV family
HLLCKODE_00046 1e-202 yeaN P transporter
HLLCKODE_00047 2.5e-130 S Domain of unknown function (DUF4336)
HLLCKODE_00048 1e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLLCKODE_00050 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HLLCKODE_00051 1.6e-61 smtB K Transcriptional regulator
HLLCKODE_00052 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
HLLCKODE_00053 1.9e-77 P Mediates zinc uptake. May also transport other divalent cations
HLLCKODE_00054 1.1e-139 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLLCKODE_00055 1.1e-56 S ParE toxin of type II toxin-antitoxin system, parDE
HLLCKODE_00056 5.3e-44
HLLCKODE_00057 5.2e-96
HLLCKODE_00058 3.4e-97 J Acetyltransferase (GNAT) domain
HLLCKODE_00059 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLLCKODE_00060 5.9e-55
HLLCKODE_00061 8.7e-60
HLLCKODE_00062 1.1e-49
HLLCKODE_00063 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
HLLCKODE_00064 2e-217 EGP Transmembrane secretion effector
HLLCKODE_00065 4.3e-22
HLLCKODE_00066 2.8e-65 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLCKODE_00068 1.5e-52 K TfoX N-terminal domain
HLLCKODE_00069 7.6e-101 L DNA alkylation repair enzyme
HLLCKODE_00070 2.7e-160 aph 2.7.11.1 KLT Aminoglycoside phosphotransferase
HLLCKODE_00071 1.9e-53 K Transcriptional regulator
HLLCKODE_00072 5.6e-30 S Protein of unknown function (DUF1648)
HLLCKODE_00073 1.4e-255 6.1.1.6 S Psort location CytoplasmicMembrane, score
HLLCKODE_00074 8.1e-131 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
HLLCKODE_00075 1.3e-105 K Transcriptional regulator
HLLCKODE_00076 1.1e-119 L Molecular Function DNA binding, Biological Process DNA recombination
HLLCKODE_00077 4.8e-45 L transposase activity
HLLCKODE_00078 2.5e-91 Q Nodulation protein S (NodS)
HLLCKODE_00079 1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLLCKODE_00080 5.9e-97 mip S hydroperoxide reductase activity
HLLCKODE_00081 1.2e-197 I acyl-CoA dehydrogenase
HLLCKODE_00082 2.9e-152 ydiA P C4-dicarboxylate transporter malic acid transport protein
HLLCKODE_00083 2e-245 msrR K Transcriptional regulator
HLLCKODE_00084 1.7e-151 pheA 4.2.1.51 E Prephenate dehydratase
HLLCKODE_00085 1e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLLCKODE_00086 3.5e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLLCKODE_00087 4.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HLLCKODE_00088 4.2e-53 yheA S Belongs to the UPF0342 family
HLLCKODE_00089 1.6e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HLLCKODE_00090 9.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLLCKODE_00091 5.5e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HLLCKODE_00092 7.7e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLLCKODE_00093 3.2e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HLLCKODE_00094 1.3e-213 ywbD 2.1.1.191 J Methyltransferase
HLLCKODE_00095 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HLLCKODE_00096 1.3e-24 WQ51_00785
HLLCKODE_00110 1e-123 U TraM recognition site of TraD and TraG
HLLCKODE_00112 4.2e-22 D Cellulose biosynthesis protein BcsQ
HLLCKODE_00115 7.2e-24 clpC O C-terminal, D2-small domain, of ClpB protein
HLLCKODE_00121 6.5e-33 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLLCKODE_00124 5.2e-12
HLLCKODE_00126 1.8e-13 dnaX 2.4.99.16, 2.7.7.7 GH13 D cell septum assembly
HLLCKODE_00127 9.9e-131 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLLCKODE_00132 4.1e-65 S CAAX amino terminal protease family protein
HLLCKODE_00133 1.4e-83 xerS L Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HLLCKODE_00134 8.1e-28 S protein disulfide oxidoreductase activity
HLLCKODE_00135 9.5e-16 xerS L Belongs to the 'phage' integrase family
HLLCKODE_00136 3.9e-24
HLLCKODE_00137 9.3e-33
HLLCKODE_00138 6.1e-132 traI 5.99.1.2 L DNA topoisomerase
HLLCKODE_00141 2.5e-30
HLLCKODE_00143 4.7e-09 S Phage derived protein Gp49-like (DUF891)
HLLCKODE_00144 2.1e-49 K peptidyl-tyrosine sulfation
HLLCKODE_00150 1.9e-41 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLLCKODE_00151 1.1e-39 S Zeta toxin
HLLCKODE_00154 7.1e-18 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLLCKODE_00158 1.5e-87 NU amidase activity
HLLCKODE_00165 2.6e-49 S Ribosomal protein S1-like RNA-binding domain
HLLCKODE_00168 4.7e-24 S Replication initiator protein A (RepA) N-terminus
HLLCKODE_00169 2.3e-40 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLLCKODE_00176 1.6e-16 L Protein of unknown function (DUF3991)
HLLCKODE_00180 4.6e-48 radC E Belongs to the UPF0758 family
HLLCKODE_00183 3.9e-08
HLLCKODE_00184 1.9e-27 dnaG L DNA primase activity
HLLCKODE_00186 2.2e-122 S Protein of unknown function DUF262
HLLCKODE_00187 3.2e-201 S Protein of unknown function DUF262
HLLCKODE_00188 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLCKODE_00189 1.1e-190 desK 2.7.13.3 T Histidine kinase
HLLCKODE_00190 3.8e-131 yvfS V ABC-2 type transporter
HLLCKODE_00191 3.7e-157 XK27_09825 V 'abc transporter, ATP-binding protein
HLLCKODE_00194 1.4e-170 fabH 2.3.1.180 I synthase III
HLLCKODE_00195 1.2e-238 6.2.1.30 H Coenzyme F390 synthetase
HLLCKODE_00196 7.3e-152 gumP S Metallo-beta-lactamase superfamily
HLLCKODE_00197 1.2e-180 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
HLLCKODE_00198 1.3e-232 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
HLLCKODE_00199 3.3e-109 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLCKODE_00200 5e-199 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
HLLCKODE_00201 2.4e-105
HLLCKODE_00202 1.3e-208 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
HLLCKODE_00204 6.3e-233 anK3 G response to abiotic stimulus
HLLCKODE_00205 0.0 hscC O Belongs to the heat shock protein 70 family
HLLCKODE_00206 5.1e-165 yocS S Transporter
HLLCKODE_00207 2.2e-81 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HLLCKODE_00208 1.6e-118 yvfS V Transporter
HLLCKODE_00209 1.6e-149 XK27_09825 V abc transporter atp-binding protein
HLLCKODE_00210 3.1e-15 liaI KT membrane
HLLCKODE_00211 1.2e-30 liaI KT membrane
HLLCKODE_00212 6.1e-93 XK27_05000 S metal cluster binding
HLLCKODE_00213 0.0 V ABC transporter (permease)
HLLCKODE_00214 3.2e-133 macB2 V ABC transporter, ATP-binding protein
HLLCKODE_00215 4.6e-161 T Histidine kinase
HLLCKODE_00216 3.5e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLCKODE_00217 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLLCKODE_00218 4.2e-223 pbuX F xanthine permease
HLLCKODE_00219 8.2e-241 norM V Multidrug efflux pump
HLLCKODE_00221 1.1e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLLCKODE_00222 2.8e-233 brnQ E Component of the transport system for branched-chain amino acids
HLLCKODE_00223 1.7e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
HLLCKODE_00224 1.8e-59 S Protein of unknown function (DUF3290)
HLLCKODE_00225 1.5e-107 S Protein of unknown function (DUF421)
HLLCKODE_00226 1.4e-16 csbD S CsbD-like
HLLCKODE_00227 1.9e-116 S Carbohydrate-binding domain-containing protein Cthe_2159
HLLCKODE_00228 5.2e-51 XK27_01300 P Protein conserved in bacteria
HLLCKODE_00229 7.1e-224 yfnA E amino acid
HLLCKODE_00230 0.0 S dextransucrase activity
HLLCKODE_00231 2.4e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
HLLCKODE_00232 6.2e-112 yxeN P ABC transporter, permease protein
HLLCKODE_00233 1e-109 ytmL P ABC transporter (Permease
HLLCKODE_00234 1.8e-164 ET ABC transporter substrate-binding protein
HLLCKODE_00235 4e-176 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
HLLCKODE_00236 2.7e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HLLCKODE_00237 1.5e-42 S Sugar efflux transporter for intercellular exchange
HLLCKODE_00238 4e-204 P FtsX-like permease family
HLLCKODE_00239 2.3e-122 V abc transporter atp-binding protein
HLLCKODE_00240 1.8e-96 K WHG domain
HLLCKODE_00241 1.8e-170 ydhF S Aldo keto reductase
HLLCKODE_00242 2.1e-211 natB CP ABC-type Na efflux pump, permease component
HLLCKODE_00243 8.3e-165 natA S abc transporter atp-binding protein
HLLCKODE_00244 5.2e-09 S Protein of unknown function (DUF3169)
HLLCKODE_00245 5.5e-27 XK27_07105 K transcriptional
HLLCKODE_00246 1.3e-35
HLLCKODE_00247 2.2e-108 XK27_02070 S nitroreductase
HLLCKODE_00248 6.5e-151 1.13.11.2 S glyoxalase
HLLCKODE_00249 8.9e-75 ywnA K Transcriptional regulator
HLLCKODE_00250 1.2e-152 E Alpha/beta hydrolase of unknown function (DUF915)
HLLCKODE_00251 8.4e-227 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLLCKODE_00252 3.7e-168 bcrA V abc transporter atp-binding protein
HLLCKODE_00253 1.8e-128 S ABC-2 family transporter protein
HLLCKODE_00254 1.3e-78 V HNH nucleases
HLLCKODE_00255 1.6e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
HLLCKODE_00256 1.5e-147 T PhoQ Sensor
HLLCKODE_00257 9.9e-126 T Xre family transcriptional regulator
HLLCKODE_00258 1.2e-109 drgA C nitroreductase
HLLCKODE_00259 1e-101 yoaK S Protein of unknown function (DUF1275)
HLLCKODE_00260 9e-40 DJ nuclease activity
HLLCKODE_00261 1.1e-30 XK27_10490
HLLCKODE_00262 1.2e-157 yvgN C reductase
HLLCKODE_00263 7.1e-209 S Tetratricopeptide repeat
HLLCKODE_00264 0.0 lacL 3.2.1.23 G -beta-galactosidase
HLLCKODE_00265 0.0 lacS G transporter
HLLCKODE_00266 1.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HLLCKODE_00267 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HLLCKODE_00268 9.8e-288 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HLLCKODE_00269 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLLCKODE_00270 3.2e-181 galR K Transcriptional regulator
HLLCKODE_00271 6e-307 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
HLLCKODE_00272 7.9e-225 vncS 2.7.13.3 T Histidine kinase
HLLCKODE_00273 2e-115 K Response regulator receiver domain protein
HLLCKODE_00274 4.6e-239 vex3 V Efflux ABC transporter, permease protein
HLLCKODE_00275 1e-108 vex2 V abc transporter atp-binding protein
HLLCKODE_00276 7.8e-177 vex1 V Efflux ABC transporter, permease protein
HLLCKODE_00277 1.5e-283 XK27_07020 S Belongs to the UPF0371 family
HLLCKODE_00279 1.9e-195 gldA 1.1.1.6 C glycerol dehydrogenase
HLLCKODE_00280 3e-176 XK27_10475 S oxidoreductase
HLLCKODE_00281 8.2e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
HLLCKODE_00282 9e-96 dhaL 2.7.1.121 S Dihydroxyacetone kinase
HLLCKODE_00283 4.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
HLLCKODE_00284 2.8e-227 thrE K Psort location CytoplasmicMembrane, score
HLLCKODE_00285 0.0 M Putative cell wall binding repeat
HLLCKODE_00286 2.4e-34 S Immunity protein 41
HLLCKODE_00287 0.0 pepO 3.4.24.71 O Peptidase family M13
HLLCKODE_00288 4.5e-07 S Enterocin A Immunity
HLLCKODE_00289 1.6e-15 S integral membrane protein
HLLCKODE_00290 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
HLLCKODE_00291 1.3e-110 yhfC S Putative membrane peptidase family (DUF2324)
HLLCKODE_00292 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HLLCKODE_00294 1.7e-258 S dextransucrase activity
HLLCKODE_00295 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HLLCKODE_00296 0.0 S dextransucrase activity
HLLCKODE_00297 4e-99 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HLLCKODE_00298 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HLLCKODE_00299 1.9e-299 S dextransucrase activity
HLLCKODE_00300 4.5e-186 S dextransucrase activity
HLLCKODE_00302 1.9e-07
HLLCKODE_00307 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLLCKODE_00308 4.9e-232 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HLLCKODE_00309 1.2e-35 XK27_02060 S Transglycosylase associated protein
HLLCKODE_00310 3.9e-72 badR K Transcriptional regulator, marr family
HLLCKODE_00311 1.1e-92 S reductase
HLLCKODE_00313 1.8e-284 ahpF O alkyl hydroperoxide reductase
HLLCKODE_00314 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
HLLCKODE_00315 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
HLLCKODE_00316 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLLCKODE_00317 1.6e-82 S Putative small multi-drug export protein
HLLCKODE_00318 2e-74 ctsR K Belongs to the CtsR family
HLLCKODE_00319 0.0 clpC O Belongs to the ClpA ClpB family
HLLCKODE_00320 5.1e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HLLCKODE_00321 5.8e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HLLCKODE_00322 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HLLCKODE_00323 3.6e-140 S SseB protein N-terminal domain
HLLCKODE_00324 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
HLLCKODE_00326 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLLCKODE_00327 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLLCKODE_00329 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLLCKODE_00330 2.7e-91 yacP S RNA-binding protein containing a PIN domain
HLLCKODE_00331 4.1e-153 degV S DegV family
HLLCKODE_00333 5.1e-22 K Transcriptional
HLLCKODE_00334 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLLCKODE_00335 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HLLCKODE_00336 2e-18
HLLCKODE_00337 1e-28 K Helix-turn-helix domain
HLLCKODE_00339 2e-149 srtB 3.4.22.70 S Sortase family
HLLCKODE_00340 1.5e-233 capA M Bacterial capsule synthesis protein
HLLCKODE_00341 1e-38 gcvR T UPF0237 protein
HLLCKODE_00342 2.3e-243 XK27_08635 S UPF0210 protein
HLLCKODE_00343 3.6e-131 ais G Phosphoglycerate mutase
HLLCKODE_00344 3.8e-137 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HLLCKODE_00345 4.4e-98 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
HLLCKODE_00346 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLLCKODE_00347 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLLCKODE_00348 2.3e-302 dnaK O Heat shock 70 kDa protein
HLLCKODE_00349 9.3e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLLCKODE_00350 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLLCKODE_00351 5.8e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HLLCKODE_00352 6.3e-79 hmpT S cog cog4720
HLLCKODE_00353 1.1e-11 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLLCKODE_00354 6.6e-166 T Diguanylate cyclase
HLLCKODE_00355 9.9e-149 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HLLCKODE_00356 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
HLLCKODE_00357 0.0
HLLCKODE_00358 3.1e-24 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLLCKODE_00359 2.7e-79
HLLCKODE_00360 5.4e-124 K Peptidase S24-like protein
HLLCKODE_00361 1.9e-94 E IrrE N-terminal-like domain
HLLCKODE_00362 6.2e-79
HLLCKODE_00363 4.5e-78
HLLCKODE_00364 2e-46
HLLCKODE_00365 8.8e-47
HLLCKODE_00366 3.3e-30 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLLCKODE_00368 1.9e-124 V abc transporter atp-binding protein
HLLCKODE_00369 0.0 V ABC transporter (Permease
HLLCKODE_00370 3.9e-128 K transcriptional regulator, MerR family
HLLCKODE_00371 4.9e-105 dnaQ 2.7.7.7 L DNA polymerase III
HLLCKODE_00372 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
HLLCKODE_00373 1.3e-63 XK27_02560 S cog cog2151
HLLCKODE_00374 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HLLCKODE_00375 1.1e-211 ytfP S Flavoprotein
HLLCKODE_00377 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLLCKODE_00378 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
HLLCKODE_00379 1e-174 ecsB U Bacterial ABC transporter protein EcsB
HLLCKODE_00380 2.6e-132 ecsA V abc transporter atp-binding protein
HLLCKODE_00381 8.6e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HLLCKODE_00385 1.6e-103
HLLCKODE_00387 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HLLCKODE_00388 1e-43 yoeB S Addiction module toxin, Txe YoeB family
HLLCKODE_00389 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HLLCKODE_00390 1.8e-198 ylbM S Belongs to the UPF0348 family
HLLCKODE_00391 1.3e-139 yqeM Q Methyltransferase domain protein
HLLCKODE_00392 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLLCKODE_00393 3e-87 entB 3.5.1.19 Q Isochorismatase family
HLLCKODE_00394 3.2e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HLLCKODE_00395 2.3e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLLCKODE_00396 7.7e-49 yhbY J RNA-binding protein
HLLCKODE_00397 1.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HLLCKODE_00398 5.1e-98 yqeG S hydrolase of the HAD superfamily
HLLCKODE_00399 2.4e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLLCKODE_00400 1.5e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HLLCKODE_00401 6.9e-60
HLLCKODE_00403 1.4e-206 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HLLCKODE_00404 1.6e-25
HLLCKODE_00405 1.4e-100 KT Transcriptional regulatory protein, C terminal
HLLCKODE_00406 2.4e-167 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HLLCKODE_00407 9.4e-116 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
HLLCKODE_00408 2.4e-96 spaE S ABC-2 family transporter protein
HLLCKODE_00409 8.1e-70 spaG S ABC-2 family transporter protein
HLLCKODE_00411 4.2e-30
HLLCKODE_00412 5e-114 U AAA-like domain
HLLCKODE_00414 8e-14
HLLCKODE_00416 9.1e-42 xisC L viral genome integration into host DNA
HLLCKODE_00418 8.8e-51
HLLCKODE_00419 0.0 V Type II restriction enzyme, methylase subunits
HLLCKODE_00422 2.8e-95 traI 5.99.1.2 L DNA topoisomerase
HLLCKODE_00427 3.6e-15 dnaX 2.4.99.16, 2.7.7.7 GH13 D cell septum assembly
HLLCKODE_00428 7.6e-131 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLLCKODE_00429 5.5e-33
HLLCKODE_00430 2.3e-19
HLLCKODE_00432 5.7e-113
HLLCKODE_00433 4.4e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLLCKODE_00434 6.1e-58
HLLCKODE_00437 1.7e-16 K Helix-turn-helix XRE-family like proteins
HLLCKODE_00438 3.7e-103 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HLLCKODE_00439 5.1e-65
HLLCKODE_00442 2.2e-42
HLLCKODE_00443 1.3e-39 L Transposase IS116 IS110 IS902
HLLCKODE_00444 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HLLCKODE_00445 2.9e-37 L COG1943 Transposase and inactivated derivatives
HLLCKODE_00446 1.7e-37 L COG1943 Transposase and inactivated derivatives
HLLCKODE_00447 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLLCKODE_00448 5.3e-226 cinA 3.5.1.42 S Belongs to the CinA family
HLLCKODE_00449 5.1e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HLLCKODE_00450 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLLCKODE_00452 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLLCKODE_00454 1.6e-68 K LytTr DNA-binding domain
HLLCKODE_00455 1.1e-77 S Protein of unknown function (DUF3021)
HLLCKODE_00456 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLLCKODE_00457 2e-53 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HLLCKODE_00458 3.4e-68 argR K Regulates arginine biosynthesis genes
HLLCKODE_00459 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HLLCKODE_00460 8.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLLCKODE_00461 2.1e-84
HLLCKODE_00463 1.9e-33
HLLCKODE_00464 2.2e-171 1.1.1.169 H Ketopantoate reductase
HLLCKODE_00465 1.3e-199 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLLCKODE_00466 5.3e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLLCKODE_00467 1.4e-237 purD 6.3.4.13 F Belongs to the GARS family
HLLCKODE_00468 4.1e-158 S CHAP domain
HLLCKODE_00469 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HLLCKODE_00470 7.6e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLLCKODE_00471 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HLLCKODE_00472 3e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLLCKODE_00473 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLLCKODE_00474 2.2e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HLLCKODE_00475 4.8e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLLCKODE_00476 2.3e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLLCKODE_00477 3.7e-137 recO L Involved in DNA repair and RecF pathway recombination
HLLCKODE_00478 6.7e-215 araT 2.6.1.1 E Aminotransferase
HLLCKODE_00479 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLLCKODE_00480 4.7e-83 usp 3.5.1.28 CBM50 S CHAP domain
HLLCKODE_00481 1.4e-82 mreD M rod shape-determining protein MreD
HLLCKODE_00482 4.9e-111 mreC M Involved in formation and maintenance of cell shape
HLLCKODE_00488 2.6e-10
HLLCKODE_00500 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HLLCKODE_00501 1.2e-267 S Psort location CytoplasmicMembrane, score
HLLCKODE_00502 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLLCKODE_00503 3.7e-73 K DNA-binding transcription factor activity
HLLCKODE_00504 4e-307 lmrA1 V abc transporter atp-binding protein
HLLCKODE_00505 0.0 lmrA2 V abc transporter atp-binding protein
HLLCKODE_00506 1.4e-110 K Acetyltransferase (GNAT) family
HLLCKODE_00507 4.8e-111 2.7.6.5 S Region found in RelA / SpoT proteins
HLLCKODE_00508 2.7e-115 T response regulator
HLLCKODE_00509 1.2e-209 sptS 2.7.13.3 T Histidine kinase
HLLCKODE_00510 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HLLCKODE_00511 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLLCKODE_00512 1.3e-159 cvfB S Protein conserved in bacteria
HLLCKODE_00513 3.7e-34 yozE S Belongs to the UPF0346 family
HLLCKODE_00514 1.5e-130 sip M LysM domain protein
HLLCKODE_00515 2e-186 phoH T phosphate starvation-inducible protein PhoH
HLLCKODE_00520 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLLCKODE_00521 9.3e-158 S reductase
HLLCKODE_00522 4.7e-168 K transcriptional regulator (lysR family)
HLLCKODE_00523 9.4e-106 S CAAX amino terminal protease family protein
HLLCKODE_00524 7.1e-262 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLLCKODE_00525 2.4e-162 coiA 3.6.4.12 S Competence protein
HLLCKODE_00526 0.0 pepF E oligoendopeptidase F
HLLCKODE_00527 5e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
HLLCKODE_00528 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
HLLCKODE_00529 2.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HLLCKODE_00530 4.6e-85 yxjI S LURP-one-related
HLLCKODE_00531 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLLCKODE_00532 2.7e-122 D CobQ CobB MinD ParA nucleotide binding domain protein
HLLCKODE_00535 2.1e-10
HLLCKODE_00536 3.3e-209 I mechanosensitive ion channel activity
HLLCKODE_00537 3.2e-22 S BRCA1 C Terminus (BRCT) domain
HLLCKODE_00540 4.9e-16 S Uncharacterized protein pXO2-11
HLLCKODE_00541 8.4e-41
HLLCKODE_00542 8e-298 trsE S COG0433 Predicted ATPase
HLLCKODE_00544 2e-162 3.4.17.14 NU amidase activity
HLLCKODE_00545 1.7e-25
HLLCKODE_00547 5.7e-32
HLLCKODE_00548 1.1e-201 repE K Primase C terminal 1 (PriCT-1)
HLLCKODE_00550 5.5e-12
HLLCKODE_00551 1.8e-16 S Thioredoxin
HLLCKODE_00553 2.1e-73
HLLCKODE_00555 1.6e-18 S the current gene model (or a revised gene model) may contain a frame shift
HLLCKODE_00556 3.5e-34 S the current gene model (or a revised gene model) may contain a frame shift
HLLCKODE_00557 4.6e-103 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
HLLCKODE_00558 2.5e-19
HLLCKODE_00559 2.6e-210 ruvB 3.6.4.12 L four-way junction helicase activity
HLLCKODE_00562 0.0 EL Toprim-like
HLLCKODE_00564 1e-190 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLLCKODE_00565 2.6e-245 clpB O Belongs to the ClpA ClpB family
HLLCKODE_00566 3.7e-17
HLLCKODE_00567 2.2e-95
HLLCKODE_00569 4.9e-15 M LPXTG cell wall anchor motif
HLLCKODE_00571 0.0 U COG3505 Type IV secretory pathway, VirD4 components
HLLCKODE_00572 2.7e-63 tnpR L Resolvase, N terminal domain
HLLCKODE_00574 8.6e-87 sigH K DNA-templated transcription, initiation
HLLCKODE_00575 5.5e-136 ykuT M mechanosensitive ion channel
HLLCKODE_00576 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLLCKODE_00577 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLLCKODE_00578 1e-306 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLLCKODE_00579 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
HLLCKODE_00580 2.7e-74 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HLLCKODE_00581 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
HLLCKODE_00582 3.2e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLLCKODE_00583 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HLLCKODE_00584 4.1e-83 nrdI F Belongs to the NrdI family
HLLCKODE_00585 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLLCKODE_00586 1.4e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLLCKODE_00587 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HLLCKODE_00588 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HLLCKODE_00589 1.9e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLLCKODE_00590 5.3e-105 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HLLCKODE_00591 1.3e-181 yhjX P Major Facilitator
HLLCKODE_00592 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLLCKODE_00593 1.7e-81 V VanZ like family
HLLCKODE_00594 2.4e-177 D nuclear chromosome segregation
HLLCKODE_00595 2.2e-123 glnQ E abc transporter atp-binding protein
HLLCKODE_00596 4.3e-270 glnP P ABC transporter
HLLCKODE_00597 3.4e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLLCKODE_00598 8.3e-18 S Protein of unknown function (DUF3021)
HLLCKODE_00599 2.9e-123 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLLCKODE_00600 5.7e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
HLLCKODE_00601 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HLLCKODE_00602 6.9e-234 sufD O assembly protein SufD
HLLCKODE_00603 3.4e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLLCKODE_00604 8e-73 nifU C SUF system FeS assembly protein, NifU family
HLLCKODE_00605 2.9e-273 sufB O assembly protein SufB
HLLCKODE_00606 4.7e-26
HLLCKODE_00607 1.8e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLLCKODE_00608 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLLCKODE_00609 1.9e-69 adcR K transcriptional
HLLCKODE_00610 2.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
HLLCKODE_00611 5.6e-128 adcB P ABC transporter (Permease
HLLCKODE_00612 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HLLCKODE_00613 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HLLCKODE_00614 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HLLCKODE_00615 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HLLCKODE_00616 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLCKODE_00617 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HLLCKODE_00618 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
HLLCKODE_00619 1.1e-95 srlA G PTS system glucitol sorbitol-specific
HLLCKODE_00620 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
HLLCKODE_00621 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
HLLCKODE_00622 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
HLLCKODE_00623 9.2e-59 L MULE transposase domain
HLLCKODE_00624 1.1e-108 L Transposase IS116 IS110 IS902
HLLCKODE_00625 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLLCKODE_00626 8.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
HLLCKODE_00627 1.4e-153 Z012_04635 K sequence-specific DNA binding
HLLCKODE_00628 1.1e-276 V ABC transporter
HLLCKODE_00629 6.1e-126 yeeN K transcriptional regulatory protein
HLLCKODE_00630 2e-47 yajC U protein transport
HLLCKODE_00631 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLLCKODE_00632 4.6e-143 cdsA 2.7.7.41 S Belongs to the CDS family
HLLCKODE_00633 1.4e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HLLCKODE_00634 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLLCKODE_00635 0.0 WQ51_06230 S ABC transporter
HLLCKODE_00636 1.4e-142 cmpC S abc transporter atp-binding protein
HLLCKODE_00637 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLLCKODE_00638 1.2e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLLCKODE_00640 1.6e-43
HLLCKODE_00641 4.2e-53 S TM2 domain
HLLCKODE_00642 5.1e-159 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLLCKODE_00643 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HLLCKODE_00644 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
HLLCKODE_00645 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HLLCKODE_00646 8.4e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HLLCKODE_00647 1.5e-144 cof S Sucrose-6F-phosphate phosphohydrolase
HLLCKODE_00648 1.7e-134 glcR K transcriptional regulator (DeoR family)
HLLCKODE_00649 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLLCKODE_00650 3.9e-70 K transcriptional
HLLCKODE_00651 6.4e-222 S COG1073 Hydrolases of the alpha beta superfamily
HLLCKODE_00652 3.2e-153 cylA V abc transporter atp-binding protein
HLLCKODE_00653 1.1e-131 cylB V ABC-2 type transporter
HLLCKODE_00654 2.6e-74 K COG3279 Response regulator of the LytR AlgR family
HLLCKODE_00655 2.3e-32 S Protein of unknown function (DUF3021)
HLLCKODE_00656 1.8e-122 mta K Transcriptional
HLLCKODE_00657 8.1e-120 yhcA V abc transporter atp-binding protein
HLLCKODE_00658 2.5e-218 macB_2 V FtsX-like permease family
HLLCKODE_00659 4.3e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLLCKODE_00660 3.8e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLLCKODE_00661 3.7e-73 yhaI S Protein of unknown function (DUF805)
HLLCKODE_00662 9.2e-253 pepC 3.4.22.40 E aminopeptidase
HLLCKODE_00663 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HLLCKODE_00664 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLLCKODE_00665 3.7e-93 ypsA S Belongs to the UPF0398 family
HLLCKODE_00666 2.1e-36 gpsB D regulation of cell shape
HLLCKODE_00667 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HLLCKODE_00668 8.1e-269 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HLLCKODE_00669 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HLLCKODE_00670 4.8e-22
HLLCKODE_00671 3.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HLLCKODE_00672 5.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
HLLCKODE_00673 1.6e-290 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLLCKODE_00674 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLLCKODE_00675 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLLCKODE_00676 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HLLCKODE_00677 8.7e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLLCKODE_00678 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HLLCKODE_00679 5e-101 ybhL S Belongs to the BI1 family
HLLCKODE_00680 3.2e-12 ycdA S Domain of unknown function (DUF4352)
HLLCKODE_00681 4.5e-241 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLLCKODE_00682 4.5e-89 K transcriptional regulator
HLLCKODE_00683 1.6e-36 yneF S UPF0154 protein
HLLCKODE_00684 1.7e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HLLCKODE_00685 9.6e-183 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLLCKODE_00686 5.6e-97 XK27_09740 S Phosphoesterase
HLLCKODE_00687 2.7e-85 ykuL S CBS domain
HLLCKODE_00688 4.1e-128 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HLLCKODE_00689 1.7e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLLCKODE_00690 3.4e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLLCKODE_00691 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLLCKODE_00692 4.4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HLLCKODE_00693 6e-258 trkH P Cation transport protein
HLLCKODE_00694 9.3e-245 trkA P Potassium transporter peripheral membrane component
HLLCKODE_00695 5.1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLLCKODE_00696 9.6e-87 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLLCKODE_00697 2.4e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HLLCKODE_00698 7.1e-156 K sequence-specific DNA binding
HLLCKODE_00699 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLLCKODE_00700 3.2e-53 yhaI L Membrane
HLLCKODE_00701 1.8e-243 S Domain of unknown function (DUF4173)
HLLCKODE_00702 6.8e-95 ureI S AmiS/UreI family transporter
HLLCKODE_00703 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HLLCKODE_00704 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HLLCKODE_00705 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HLLCKODE_00706 6.6e-78 ureE O enzyme active site formation
HLLCKODE_00707 1.7e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HLLCKODE_00708 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HLLCKODE_00709 4.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HLLCKODE_00710 2.1e-177 cbiM P PDGLE domain
HLLCKODE_00711 1.4e-136 P cobalt transport protein
HLLCKODE_00712 6.9e-130 cbiO P ABC transporter
HLLCKODE_00713 1.1e-137 ET ABC transporter substrate-binding protein
HLLCKODE_00714 4.1e-164 metQ M Belongs to the NlpA lipoprotein family
HLLCKODE_00715 1.7e-262 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HLLCKODE_00716 2e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLLCKODE_00717 1.2e-99 metI P ABC transporter (Permease
HLLCKODE_00718 5.7e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HLLCKODE_00719 7.1e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HLLCKODE_00720 6.7e-93 S UPF0397 protein
HLLCKODE_00721 2.9e-304 ykoD P abc transporter atp-binding protein
HLLCKODE_00722 7.2e-147 cbiQ P cobalt transport
HLLCKODE_00723 1.8e-116 ktrA P COG0569 K transport systems, NAD-binding component
HLLCKODE_00724 6.4e-233 P COG0168 Trk-type K transport systems, membrane components
HLLCKODE_00725 2.7e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HLLCKODE_00726 2e-89 yceD K metal-binding, possibly nucleic acid-binding protein
HLLCKODE_00727 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLCKODE_00728 2.5e-278 T PhoQ Sensor
HLLCKODE_00729 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLLCKODE_00730 2.4e-212 dnaB L Replication initiation and membrane attachment
HLLCKODE_00731 1.3e-165 dnaI L Primosomal protein DnaI
HLLCKODE_00732 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HLLCKODE_00733 2.8e-103
HLLCKODE_00734 1.5e-228 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLLCKODE_00735 2.5e-62 manO S protein conserved in bacteria
HLLCKODE_00736 4e-167 manN G PTS system mannose fructose sorbose family IID component
HLLCKODE_00737 1.2e-114 manM G pts system
HLLCKODE_00738 4.9e-174 manL 2.7.1.191 G pts system
HLLCKODE_00739 2.2e-66 manO S Protein conserved in bacteria
HLLCKODE_00740 1.4e-159 manN G PTS system mannose fructose sorbose family IID component
HLLCKODE_00741 4.8e-132 manY G pts system
HLLCKODE_00742 3.1e-168 manL 2.7.1.191 G pts system
HLLCKODE_00743 1.2e-137 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HLLCKODE_00744 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HLLCKODE_00745 1.6e-247 pbuO S permease
HLLCKODE_00746 2.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HLLCKODE_00747 5.3e-87 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
HLLCKODE_00748 5.5e-191 brpA K Transcriptional
HLLCKODE_00749 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
HLLCKODE_00750 2.4e-196 nusA K Participates in both transcription termination and antitermination
HLLCKODE_00751 4e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HLLCKODE_00752 8e-42 ylxQ J ribosomal protein
HLLCKODE_00753 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLLCKODE_00754 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLLCKODE_00755 5.5e-98 yvdD 3.2.2.10 S Belongs to the LOG family
HLLCKODE_00756 5.1e-189 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HLLCKODE_00757 4.2e-267 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLLCKODE_00758 8.3e-277 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HLLCKODE_00759 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HLLCKODE_00760 2.6e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
HLLCKODE_00761 5.6e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HLLCKODE_00762 2.6e-264 L Transposase
HLLCKODE_00763 3e-304 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HLLCKODE_00764 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HLLCKODE_00765 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLLCKODE_00766 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLLCKODE_00767 6.4e-73 ylbF S Belongs to the UPF0342 family
HLLCKODE_00768 7.1e-46 ylbG S UPF0298 protein
HLLCKODE_00769 2.6e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HLLCKODE_00770 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HLLCKODE_00771 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
HLLCKODE_00772 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HLLCKODE_00773 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HLLCKODE_00774 6.6e-111 acuB S CBS domain
HLLCKODE_00775 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HLLCKODE_00776 2.2e-108 yvyE 3.4.13.9 S YigZ family
HLLCKODE_00777 2.4e-237 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HLLCKODE_00778 7.6e-99 comFC K competence protein
HLLCKODE_00779 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLLCKODE_00780 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
HLLCKODE_00781 3.5e-117 S HAD hydrolase, family IA, variant 3
HLLCKODE_00782 6.2e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HLLCKODE_00783 5.2e-72 marR K Transcriptional regulator, MarR family
HLLCKODE_00784 3.2e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLLCKODE_00785 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLLCKODE_00786 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HLLCKODE_00787 7.2e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HLLCKODE_00788 6.2e-126 IQ reductase
HLLCKODE_00789 5.7e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLLCKODE_00790 2.5e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLLCKODE_00791 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLLCKODE_00792 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HLLCKODE_00793 3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLLCKODE_00794 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HLLCKODE_00795 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLLCKODE_00796 2.4e-207 rny D Endoribonuclease that initiates mRNA decay
HLLCKODE_00797 6.8e-112 fruR K transcriptional
HLLCKODE_00798 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HLLCKODE_00799 0.0 fruA 2.7.1.202 G phosphotransferase system
HLLCKODE_00800 9e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HLLCKODE_00801 1.2e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HLLCKODE_00803 2e-208 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HLLCKODE_00804 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLLCKODE_00805 6.9e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HLLCKODE_00806 4.1e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HLLCKODE_00807 9e-82 2.3.1.128 K acetyltransferase
HLLCKODE_00808 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HLLCKODE_00809 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HLLCKODE_00810 1.1e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLLCKODE_00811 5e-63 WQ51_03320 S cog cog4835
HLLCKODE_00812 1.6e-146 XK27_08360 S EDD domain protein, DegV family
HLLCKODE_00813 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLLCKODE_00814 9.3e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLLCKODE_00815 0.0 yfmR S abc transporter atp-binding protein
HLLCKODE_00816 1.7e-26 U response to pH
HLLCKODE_00817 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HLLCKODE_00818 1.8e-209 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HLLCKODE_00819 5.9e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HLLCKODE_00820 4.7e-85 ebsA S Family of unknown function (DUF5322)
HLLCKODE_00821 5.5e-17 M LysM domain
HLLCKODE_00822 4.3e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HLLCKODE_00823 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLLCKODE_00824 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HLLCKODE_00825 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLLCKODE_00826 9.7e-49 XK27_03610 K Gnat family
HLLCKODE_00827 2.8e-88 yybC
HLLCKODE_00828 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HLLCKODE_00829 3.4e-266 pepV 3.5.1.18 E Dipeptidase
HLLCKODE_00830 3.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
HLLCKODE_00831 1.1e-226 V Glucan-binding protein C
HLLCKODE_00832 7.4e-253 V Glucan-binding protein C
HLLCKODE_00833 8.1e-120 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLLCKODE_00834 2.7e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HLLCKODE_00835 6.8e-85 S Protein of unknown function (DUF1697)
HLLCKODE_00836 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HLLCKODE_00837 3.2e-50 S LemA family
HLLCKODE_00838 2.8e-163 clcA_2 P chloride
HLLCKODE_00839 1.5e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HLLCKODE_00840 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HLLCKODE_00841 8.8e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HLLCKODE_00842 5.8e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HLLCKODE_00843 1.2e-110 cps4C M biosynthesis protein
HLLCKODE_00844 5.9e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
HLLCKODE_00845 2.7e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HLLCKODE_00846 3.1e-220 rgpAc GT4 M group 1 family protein
HLLCKODE_00847 1.8e-212 wcoF M Glycosyltransferase, group 1 family protein
HLLCKODE_00848 6.4e-84 Z012_10770 M Domain of unknown function (DUF1919)
HLLCKODE_00849 1.1e-173 M Glycosyltransferase, group 2 family protein
HLLCKODE_00850 1.5e-154 M Glycosyltransferase like family 2
HLLCKODE_00851 1.1e-172
HLLCKODE_00852 5.9e-250 epsU S Polysaccharide biosynthesis protein
HLLCKODE_00853 4.7e-47 K Helix-turn-helix
HLLCKODE_00854 2e-118 mleR K malolactic fermentation system
HLLCKODE_00855 2.6e-127 XK27_00785 S CAAX protease self-immunity
HLLCKODE_00856 2.9e-233 EGP Major facilitator Superfamily
HLLCKODE_00857 5.5e-63 rmaI K Transcriptional regulator, MarR family
HLLCKODE_00858 4.5e-92 maa 2.3.1.79 GK Maltose O-acetyltransferase
HLLCKODE_00859 3.4e-64 2.7.13.3 T Histidine kinase
HLLCKODE_00860 2.3e-74 K Transcriptional regulatory protein, C terminal
HLLCKODE_00862 3.8e-15
HLLCKODE_00863 6.6e-88 V abc transporter atp-binding protein
HLLCKODE_00864 0.0 3.5.1.28 M domain protein
HLLCKODE_00865 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HLLCKODE_00866 2.7e-23
HLLCKODE_00869 1.1e-09 sraP UW domain, Protein
HLLCKODE_00872 8.1e-150 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
HLLCKODE_00873 0.0 3.5.1.28 NU amidase activity
HLLCKODE_00874 1.3e-288 lpdA 1.8.1.4 C Dehydrogenase
HLLCKODE_00875 1.2e-210 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLLCKODE_00876 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLLCKODE_00877 1.9e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HLLCKODE_00878 1.3e-200 hpk9 2.7.13.3 T protein histidine kinase activity
HLLCKODE_00879 1.6e-225 2.7.13.3 T protein histidine kinase activity
HLLCKODE_00880 2.1e-301 S the current gene model (or a revised gene model) may contain a frame shift
HLLCKODE_00881 5e-232 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLLCKODE_00882 1.6e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLLCKODE_00883 5.4e-212 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLLCKODE_00884 1.7e-246 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HLLCKODE_00885 2.4e-153 rssA S Phospholipase, patatin family
HLLCKODE_00886 8.4e-100 estA E Lysophospholipase L1 and related esterases
HLLCKODE_00887 9.8e-278 S unusual protein kinase
HLLCKODE_00888 4.1e-38 S granule-associated protein
HLLCKODE_00889 9.8e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HLLCKODE_00890 1.5e-195 S hmm pf01594
HLLCKODE_00891 2.1e-103 G Belongs to the phosphoglycerate mutase family
HLLCKODE_00892 1.7e-108 G Belongs to the phosphoglycerate mutase family
HLLCKODE_00893 1.6e-108 pgm G Belongs to the phosphoglycerate mutase family
HLLCKODE_00894 1e-137 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HLLCKODE_00896 8.7e-190 wbbI M transferase activity, transferring glycosyl groups
HLLCKODE_00897 2.5e-186 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HLLCKODE_00898 1.7e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
HLLCKODE_00899 1.6e-94 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HLLCKODE_00900 4.5e-222 G COG0457 FOG TPR repeat
HLLCKODE_00901 1.8e-175 yubA S permease
HLLCKODE_00902 7.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HLLCKODE_00903 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HLLCKODE_00904 3.2e-124 ftsE D cell division ATP-binding protein FtsE
HLLCKODE_00905 2.1e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLLCKODE_00906 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HLLCKODE_00907 4.4e-152 yjjH S Calcineurin-like phosphoesterase
HLLCKODE_00908 2.7e-129 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HLLCKODE_00909 0.0 pacL 3.6.3.8 P cation transport ATPase
HLLCKODE_00910 1.2e-67 ywiB S Domain of unknown function (DUF1934)
HLLCKODE_00911 5e-135 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
HLLCKODE_00912 7.8e-146 yidA S hydrolases of the HAD superfamily
HLLCKODE_00913 4.3e-225 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HLLCKODE_00914 9.7e-56 S Protein of unknown function (DUF454)
HLLCKODE_00915 2.7e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HLLCKODE_00916 9.6e-234 vicK 2.7.13.3 T Histidine kinase
HLLCKODE_00917 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLCKODE_00918 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HLLCKODE_00919 1.8e-142 peb1A ET Belongs to the bacterial solute-binding protein 3 family
HLLCKODE_00920 1.9e-116 gltJ P ABC transporter (Permease
HLLCKODE_00921 5e-111 tcyB_2 P ABC transporter (permease)
HLLCKODE_00922 1.3e-154 endA F DNA RNA non-specific endonuclease
HLLCKODE_00923 2.7e-25 epuA S DNA-directed RNA polymerase subunit beta
HLLCKODE_00924 1.6e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLLCKODE_00925 1e-193 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HLLCKODE_00926 7.4e-247 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
HLLCKODE_00928 1e-131
HLLCKODE_00929 2.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLLCKODE_00930 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HLLCKODE_00931 9e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLLCKODE_00932 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLLCKODE_00933 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLLCKODE_00934 2e-33 secG U Preprotein translocase subunit SecG
HLLCKODE_00935 1e-221 mdtG EGP Major facilitator Superfamily
HLLCKODE_00936 4e-91 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLLCKODE_00937 9.9e-109 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLLCKODE_00938 1.7e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLLCKODE_00939 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HLLCKODE_00940 3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLLCKODE_00941 1.3e-143 licT K antiterminator
HLLCKODE_00942 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLLCKODE_00943 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HLLCKODE_00944 2.4e-142 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLLCKODE_00945 2.4e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLLCKODE_00946 6.1e-148 I Alpha/beta hydrolase family
HLLCKODE_00947 6.6e-08
HLLCKODE_00948 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HLLCKODE_00949 1.6e-77 feoA P FeoA domain protein
HLLCKODE_00950 5.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
HLLCKODE_00951 1.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HLLCKODE_00952 1e-34 ykuJ S protein conserved in bacteria
HLLCKODE_00953 3.4e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLLCKODE_00954 0.0 clpE O Belongs to the ClpA ClpB family
HLLCKODE_00955 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HLLCKODE_00956 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
HLLCKODE_00957 1.3e-171 S oxidoreductase
HLLCKODE_00958 2.5e-228 murN 2.3.2.16 V FemAB family
HLLCKODE_00959 7.1e-116 M Pfam SNARE associated Golgi protein
HLLCKODE_00960 2.1e-106 S Domain of Unknown Function with PDB structure (DUF3862)
HLLCKODE_00963 1.2e-23 M Glycosyl transferase family 2
HLLCKODE_00964 1.2e-172 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLLCKODE_00965 2.2e-46 coiA 3.6.4.12 S Competence protein
HLLCKODE_00966 7.2e-186 L PFAM Integrase, catalytic core
HLLCKODE_00967 6e-20 M Pilin isopeptide linkage domain protein
HLLCKODE_00968 8.2e-233 M domain protein
HLLCKODE_00969 6.7e-89 H Methyltransferase
HLLCKODE_00970 2e-21 XK27_10050 K Peptidase S24-like
HLLCKODE_00973 5.2e-62 XK27_00590
HLLCKODE_00974 2.5e-62 P arsenate reductase (glutaredoxin) activity
HLLCKODE_00975 9.7e-36 XK27_00545 U This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HLLCKODE_00976 3.4e-34
HLLCKODE_00977 1.8e-81 nprA K Cro/C1-type HTH DNA-binding domain
HLLCKODE_00978 1.7e-126 2.7.1.176 O Zeta toxin
HLLCKODE_00979 3.5e-163 xerC L Phage integrase family
HLLCKODE_00981 5.6e-154 6.3.2.2, 6.3.2.4 M Belongs to the D-alanine--D-alanine ligase family
HLLCKODE_00982 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLLCKODE_00984 6.5e-99 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLLCKODE_00985 7.1e-101 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HLLCKODE_00988 3e-14 coiA 3.6.4.12 S Competence protein
HLLCKODE_00989 3.4e-16 T peptidase
HLLCKODE_00990 2.9e-146 rarD S Transporter
HLLCKODE_00991 3.5e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLLCKODE_00992 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HLLCKODE_00993 1.4e-132 yxkH G deacetylase
HLLCKODE_00994 5.7e-203 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HLLCKODE_00995 3.8e-123 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HLLCKODE_00996 8.6e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLLCKODE_00997 2.5e-181 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLLCKODE_00998 2.6e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HLLCKODE_00999 1.2e-140 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLLCKODE_01000 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
HLLCKODE_01002 6.4e-230 2.7.13.3 T GHKL domain
HLLCKODE_01003 2e-132 agrA KT phosphorelay signal transduction system
HLLCKODE_01004 3.5e-205 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HLLCKODE_01005 5.2e-94 bipA Q Transposase
HLLCKODE_01006 8.1e-86 L Transposase
HLLCKODE_01007 0.0 zmpB M signal peptide protein, YSIRK family
HLLCKODE_01008 0.0 GM domain, Protein
HLLCKODE_01009 4.9e-54
HLLCKODE_01010 1.8e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLLCKODE_01011 0.0 sbcC L ATPase involved in DNA repair
HLLCKODE_01012 8.5e-143
HLLCKODE_01013 1.9e-36 S PFAM Uncharacterised protein family (UPF0153)
HLLCKODE_01014 2.1e-288 adcA P Belongs to the bacterial solute-binding protein 9 family
HLLCKODE_01015 8.2e-143 XK27_10720 D peptidase activity
HLLCKODE_01016 1.5e-274 pepD E Dipeptidase
HLLCKODE_01017 5.7e-161 whiA K May be required for sporulation
HLLCKODE_01018 1.8e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HLLCKODE_01019 5.5e-161 rapZ S Displays ATPase and GTPase activities
HLLCKODE_01020 2.9e-134 yejC S cyclic nucleotide-binding protein
HLLCKODE_01021 5.2e-202 D nuclear chromosome segregation
HLLCKODE_01022 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HLLCKODE_01023 7.2e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HLLCKODE_01024 6.9e-80 queD 4.1.2.50, 4.2.3.12 H synthase
HLLCKODE_01025 2.6e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HLLCKODE_01026 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HLLCKODE_01027 8.1e-200 pmrB EGP Major facilitator Superfamily
HLLCKODE_01028 4.8e-19
HLLCKODE_01029 9.3e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HLLCKODE_01030 3.7e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HLLCKODE_01031 3e-76 ypmB S Protein conserved in bacteria
HLLCKODE_01032 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HLLCKODE_01033 9.8e-112 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HLLCKODE_01034 2.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLLCKODE_01035 3.4e-14 rpmH J Ribosomal protein L34
HLLCKODE_01036 1.2e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HLLCKODE_01037 4e-99 K Transcriptional regulator
HLLCKODE_01038 3.4e-170 jag S RNA-binding protein
HLLCKODE_01039 9.2e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLLCKODE_01040 3.5e-52 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLLCKODE_01041 4.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
HLLCKODE_01042 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLLCKODE_01043 7.2e-130 fasA KT Response regulator of the LytR AlgR family
HLLCKODE_01044 5.2e-224 fasC T protein histidine kinase activity
HLLCKODE_01045 2.3e-208 hpk9 2.7.13.3 T protein histidine kinase activity
HLLCKODE_01046 9.5e-153 hpk9 2.7.13.3 T protein histidine kinase activity
HLLCKODE_01047 9.1e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HLLCKODE_01048 8.7e-281 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLLCKODE_01049 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HLLCKODE_01050 5.3e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLLCKODE_01051 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLLCKODE_01052 1.2e-50 S Protein of unknown function (DUF3397)
HLLCKODE_01053 5e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HLLCKODE_01054 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HLLCKODE_01055 1.5e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLLCKODE_01056 1.7e-76 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HLLCKODE_01057 3.2e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HLLCKODE_01058 1.4e-107 XK27_09620 S FMN reductase (NADPH) activity
HLLCKODE_01059 7.9e-230 XK27_09615 C reductase
HLLCKODE_01060 9.6e-141 fnt P Formate nitrite transporter
HLLCKODE_01061 1.9e-95 XK27_08585 S Psort location CytoplasmicMembrane, score
HLLCKODE_01062 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HLLCKODE_01063 1.6e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HLLCKODE_01064 1.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HLLCKODE_01065 2.9e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLLCKODE_01066 7.4e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLLCKODE_01067 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLLCKODE_01068 1.3e-126 S HAD hydrolase, family IA, variant
HLLCKODE_01069 2.3e-156 rrmA 2.1.1.187 Q methyltransferase
HLLCKODE_01072 7.3e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLLCKODE_01073 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLLCKODE_01074 8.3e-37 yeeD O sulfur carrier activity
HLLCKODE_01075 3.3e-189 yeeE S Sulphur transport
HLLCKODE_01076 1.1e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLLCKODE_01078 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HLLCKODE_01079 1.6e-08 XK27_10305 S Domain of unknown function (DUF4651)
HLLCKODE_01080 1.8e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HLLCKODE_01081 2.8e-129 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLLCKODE_01082 1.3e-93 S CAAX amino terminal protease family protein
HLLCKODE_01084 5.4e-105 V CAAX protease self-immunity
HLLCKODE_01085 8.8e-27 lanR K sequence-specific DNA binding
HLLCKODE_01086 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLLCKODE_01087 1.5e-175 ytxK 2.1.1.72 L DNA methylase
HLLCKODE_01088 1.2e-12 comGF U Putative Competence protein ComGF
HLLCKODE_01089 4.9e-70 comGF U Competence protein ComGF
HLLCKODE_01090 1.7e-16 NU Type II secretory pathway pseudopilin
HLLCKODE_01091 2.3e-67 cglD NU Competence protein
HLLCKODE_01092 2.2e-43 comGC U Required for transformation and DNA binding
HLLCKODE_01093 4.8e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLLCKODE_01094 1.6e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLLCKODE_01095 2.9e-68 S cog cog4699
HLLCKODE_01096 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLLCKODE_01097 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLLCKODE_01098 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HLLCKODE_01099 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLLCKODE_01100 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLLCKODE_01101 5e-76 ilvN 2.2.1.6 E Acetolactate synthase
HLLCKODE_01102 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HLLCKODE_01103 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HLLCKODE_01104 7.1e-303 yloV S kinase related to dihydroxyacetone kinase
HLLCKODE_01105 1.4e-57 asp S cog cog1302
HLLCKODE_01106 5.1e-224 norN V Mate efflux family protein
HLLCKODE_01107 1.9e-275 thrC 4.2.3.1 E Threonine synthase
HLLCKODE_01110 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HLLCKODE_01111 0.0 pepO 3.4.24.71 O Peptidase family M13
HLLCKODE_01112 6.9e-63 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HLLCKODE_01113 6e-126 treR K trehalose operon
HLLCKODE_01114 5.1e-96 ywlG S Belongs to the UPF0340 family
HLLCKODE_01117 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
HLLCKODE_01119 1.6e-246 6.3.2.2 H gamma-glutamylcysteine synthetase
HLLCKODE_01120 6.5e-224 L Transposase
HLLCKODE_01121 4.4e-62 rplQ J ribosomal protein l17
HLLCKODE_01122 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLLCKODE_01123 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLLCKODE_01124 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLLCKODE_01125 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HLLCKODE_01126 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLLCKODE_01127 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLLCKODE_01128 6.2e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLLCKODE_01129 5.7e-58 rplO J binds to the 23S rRNA
HLLCKODE_01130 1.9e-23 rpmD J ribosomal protein l30
HLLCKODE_01131 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLLCKODE_01132 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLLCKODE_01133 1.1e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLLCKODE_01134 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLLCKODE_01135 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLLCKODE_01136 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLLCKODE_01137 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLLCKODE_01138 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLLCKODE_01139 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLLCKODE_01140 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HLLCKODE_01141 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLLCKODE_01142 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLLCKODE_01143 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLLCKODE_01144 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLLCKODE_01145 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLLCKODE_01146 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLLCKODE_01147 9.7e-104 rplD J Forms part of the polypeptide exit tunnel
HLLCKODE_01148 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLLCKODE_01149 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HLLCKODE_01150 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLLCKODE_01151 0.0 XK27_09800 I Acyltransferase
HLLCKODE_01152 1.6e-33 XK27_09805 S MORN repeat protein
HLLCKODE_01153 9.8e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLLCKODE_01154 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLLCKODE_01155 3.2e-89 adk 2.7.4.3 F topology modulation protein
HLLCKODE_01157 4.7e-197 ltrA S Low temperature requirement protein
HLLCKODE_01158 2.5e-173 yeiH S membrane
HLLCKODE_01159 8e-88 K sequence-specific DNA binding
HLLCKODE_01160 1.5e-156 L Replication initiation factor
HLLCKODE_01161 1.4e-18 S Domain of unknown function (DUF3173)
HLLCKODE_01162 1.6e-213 int L Belongs to the 'phage' integrase family
HLLCKODE_01164 8.2e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HLLCKODE_01165 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HLLCKODE_01166 6.3e-44 yrzL S Belongs to the UPF0297 family
HLLCKODE_01167 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLLCKODE_01168 3.2e-44 yrzB S Belongs to the UPF0473 family
HLLCKODE_01169 1.3e-285 ccs S the current gene model (or a revised gene model) may contain a frame shift
HLLCKODE_01170 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HLLCKODE_01171 7.5e-14
HLLCKODE_01172 3.3e-86 XK27_10930 K acetyltransferase
HLLCKODE_01173 1.9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLLCKODE_01174 3.3e-119 yaaA S Belongs to the UPF0246 family
HLLCKODE_01175 9.3e-167 XK27_01785 S cog cog1284
HLLCKODE_01176 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLLCKODE_01178 1.8e-237 hisS 6.1.1.21 J histidyl-tRNA synthetase
HLLCKODE_01179 5.5e-80 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HLLCKODE_01180 8.9e-51 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HLLCKODE_01181 1.4e-07 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HLLCKODE_01182 1.2e-218 metE 2.1.1.14 E Methionine synthase
HLLCKODE_01183 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HLLCKODE_01184 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HLLCKODE_01185 3.3e-28
HLLCKODE_01188 7.4e-80
HLLCKODE_01189 2.9e-46 K DNA-binding protein
HLLCKODE_01193 2.7e-121 D ftsk spoiiie
HLLCKODE_01194 2.1e-206 S Replication initiation factor
HLLCKODE_01195 2.8e-28 S MerR HTH family regulatory protein
HLLCKODE_01196 6.8e-221 sip L Belongs to the 'phage' integrase family
HLLCKODE_01197 9.8e-55 K HxlR-like helix-turn-helix
HLLCKODE_01198 2.2e-15 S Pseudomonas avirulence D protein (AvrD)
HLLCKODE_01199 2.5e-237 mmr P Major Facilitator Superfamily
HLLCKODE_01200 1e-110 nudL L hydrolase
HLLCKODE_01201 3.2e-50 K transcriptional regulator, PadR family
HLLCKODE_01202 8.3e-57 XK27_06920 S Protein of unknown function (DUF1700)
HLLCKODE_01203 3.2e-102 S Putative adhesin
HLLCKODE_01204 1.5e-157 XK27_06930 V domain protein
HLLCKODE_01205 4.6e-94 XK27_06935 K transcriptional regulator
HLLCKODE_01206 2.7e-53 ypaA M Membrane
HLLCKODE_01207 1.1e-10
HLLCKODE_01208 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLLCKODE_01209 1.8e-47 veg S Biofilm formation stimulator VEG
HLLCKODE_01210 3.2e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HLLCKODE_01211 2.2e-73 rplI J binds to the 23S rRNA
HLLCKODE_01212 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HLLCKODE_01213 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLLCKODE_01214 7.8e-98 yvbG U UPF0056 membrane protein
HLLCKODE_01215 2.1e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLLCKODE_01216 1.8e-145 S Bacterial membrane protein, YfhO
HLLCKODE_01217 5.6e-150 S Bacterial membrane protein, YfhO
HLLCKODE_01218 4.5e-65 isaA GH23 M Immunodominant staphylococcal antigen A
HLLCKODE_01219 2.5e-61 lytE M LysM domain protein
HLLCKODE_01220 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLLCKODE_01221 1.4e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLLCKODE_01222 2.7e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLLCKODE_01223 2.6e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLLCKODE_01224 1.7e-127 S sequence-specific DNA binding
HLLCKODE_01225 4.1e-234 ymfH S Peptidase M16
HLLCKODE_01226 1.8e-226 ymfF S Peptidase M16
HLLCKODE_01227 6.4e-58 yaaA S S4 domain protein YaaA
HLLCKODE_01228 1.2e-200 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLLCKODE_01229 2.3e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HLLCKODE_01230 7.2e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HLLCKODE_01231 9.3e-153 yvjA S membrane
HLLCKODE_01232 1.9e-305 ybiT S abc transporter atp-binding protein
HLLCKODE_01233 0.0 XK27_10405 S Bacterial membrane protein YfhO
HLLCKODE_01237 2.2e-117 yoaK S Protein of unknown function (DUF1275)
HLLCKODE_01238 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLLCKODE_01239 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HLLCKODE_01240 4.2e-133 parB K Belongs to the ParB family
HLLCKODE_01241 3.2e-253 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLLCKODE_01242 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLLCKODE_01243 3.2e-29 yyzM S Protein conserved in bacteria
HLLCKODE_01244 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLLCKODE_01245 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLLCKODE_01246 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLLCKODE_01247 6.3e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HLLCKODE_01248 3e-60 divIC D Septum formation initiator
HLLCKODE_01250 7.9e-233 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HLLCKODE_01251 4.7e-230 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLLCKODE_01252 4.2e-95 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HLLCKODE_01253 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLLCKODE_01254 1.2e-208 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLLCKODE_01255 2.2e-168 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLLCKODE_01256 1.1e-300 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLLCKODE_01257 1.4e-84 ytsP 1.8.4.14 T GAF domain-containing protein
HLLCKODE_01258 6.9e-159 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLLCKODE_01259 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
HLLCKODE_01262 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLLCKODE_01263 9.5e-212 XK27_05110 P Chloride transporter ClC family
HLLCKODE_01264 1.8e-38 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HLLCKODE_01265 2.1e-280 clcA P Chloride transporter, ClC family
HLLCKODE_01266 1e-75 fld C Flavodoxin
HLLCKODE_01267 2.8e-18 XK27_08880
HLLCKODE_01268 5.5e-127 XK27_08875 O Zinc-dependent metalloprotease
HLLCKODE_01269 9.5e-149 estA CE1 S Esterase
HLLCKODE_01270 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLLCKODE_01271 3.1e-136 XK27_08845 S abc transporter atp-binding protein
HLLCKODE_01272 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HLLCKODE_01273 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
HLLCKODE_01274 1.7e-18 S Domain of unknown function (DUF4649)
HLLCKODE_01275 2.8e-241 Q the current gene model (or a revised gene model) may contain a frame shift
HLLCKODE_01276 9.7e-155 cjaA ET ABC transporter substrate-binding protein
HLLCKODE_01277 2.2e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
HLLCKODE_01278 3e-106 P ABC transporter (Permease
HLLCKODE_01279 1.3e-114 papP P ABC transporter (Permease
HLLCKODE_01280 2.1e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HLLCKODE_01281 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
HLLCKODE_01282 0.0 copA 3.6.3.54 P P-type ATPase
HLLCKODE_01283 1.2e-73 copY K negative regulation of transcription, DNA-templated
HLLCKODE_01286 3.5e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLLCKODE_01287 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLLCKODE_01288 2.5e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HLLCKODE_01289 1.2e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HLLCKODE_01290 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLLCKODE_01291 2.6e-103 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HLLCKODE_01292 1.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLLCKODE_01293 8.4e-39 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
HLLCKODE_01294 0.0 L helicase activity
HLLCKODE_01295 6.4e-190 nss M transferase activity, transferring glycosyl groups
HLLCKODE_01296 3.6e-16 S Accessory secretory protein Sec, Asp5
HLLCKODE_01297 2.6e-17 S Accessory secretory protein Sec Asp4
HLLCKODE_01298 9.7e-242 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HLLCKODE_01299 1.4e-278 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HLLCKODE_01300 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLLCKODE_01301 5e-78 asp3 S Accessory Sec system protein Asp3
HLLCKODE_01302 1.9e-289 asp2 3.4.11.5 S Accessory Sec system protein Asp2
HLLCKODE_01303 3.6e-288 asp1 S Accessory Sec system protein Asp1
HLLCKODE_01304 1.6e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HLLCKODE_01305 0.0 M family 8
HLLCKODE_01306 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HLLCKODE_01307 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLLCKODE_01308 0.0 dnaE 2.7.7.7 L DNA polymerase
HLLCKODE_01309 9.5e-85 yfjR K regulation of single-species biofilm formation
HLLCKODE_01312 4.7e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
HLLCKODE_01313 9e-142 S ABC-2 family transporter protein
HLLCKODE_01314 5.6e-141 S ABC-2 family transporter protein
HLLCKODE_01315 8.8e-78 K Acetyltransferase (GNAT) domain
HLLCKODE_01316 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
HLLCKODE_01317 2.5e-56
HLLCKODE_01318 2.2e-83 V ABC transporter
HLLCKODE_01319 7.1e-129 3.4.21.83 E Prolyl oligopeptidase family
HLLCKODE_01320 2.9e-266 KLT Protein kinase domain
HLLCKODE_01321 4.8e-139 P ABC transporter transmembrane region
HLLCKODE_01323 2.4e-32 K Transcriptional regulator C-terminal region
HLLCKODE_01324 1.5e-271 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HLLCKODE_01325 3.2e-57
HLLCKODE_01326 0.0 ctpE P E1-E2 ATPase
HLLCKODE_01327 1.5e-26 3.2.1.26 GH32 G Psort location Cytoplasmic, score
HLLCKODE_01328 1.9e-187 L Transposase
HLLCKODE_01329 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HLLCKODE_01330 2.4e-181 ccpA K Catabolite control protein A
HLLCKODE_01331 1.6e-199 yyaQ S YjbR
HLLCKODE_01332 9e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HLLCKODE_01333 3.1e-75 yueI S Protein of unknown function (DUF1694)
HLLCKODE_01334 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLLCKODE_01335 2e-36 L Transposase
HLLCKODE_01336 4.5e-310 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
HLLCKODE_01337 4.8e-163 mleP S Sodium Bile acid symporter family
HLLCKODE_01338 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLLCKODE_01342 2e-161 ppaC 3.6.1.1 C inorganic pyrophosphatase
HLLCKODE_01343 1.5e-101 S Domain of unknown function (DUF1803)
HLLCKODE_01344 7.8e-102 ygaC J Belongs to the UPF0374 family
HLLCKODE_01345 2.3e-134 recX 2.4.1.337 GT4 S Regulatory protein RecX
HLLCKODE_01346 4.5e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLLCKODE_01347 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
HLLCKODE_01350 2.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLLCKODE_01351 3.3e-118 ywaF S Integral membrane protein (intg_mem_TP0381)
HLLCKODE_01353 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLLCKODE_01354 1.1e-196 yjbB G Permeases of the major facilitator superfamily
HLLCKODE_01355 5.2e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HLLCKODE_01356 3.1e-96 thiT S Thiamine transporter
HLLCKODE_01357 2.5e-62 yjqA S Bacterial PH domain
HLLCKODE_01358 3.1e-151 corA P CorA-like protein
HLLCKODE_01359 1.7e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLLCKODE_01360 3.9e-41 yazA L endonuclease containing a URI domain
HLLCKODE_01361 9.2e-125 yabB 2.1.1.223 L Methyltransferase
HLLCKODE_01362 4e-154 nodB3 G Polysaccharide deacetylase
HLLCKODE_01363 9.2e-141 plsC 2.3.1.51 I Acyltransferase
HLLCKODE_01364 4.9e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HLLCKODE_01365 0.0 comEC S Competence protein ComEC
HLLCKODE_01366 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLLCKODE_01367 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HLLCKODE_01368 1.5e-231 ytoI K transcriptional regulator containing CBS domains
HLLCKODE_01369 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HLLCKODE_01370 2.8e-163 rbn E Belongs to the UPF0761 family
HLLCKODE_01371 1.7e-85 ccl S cog cog4708
HLLCKODE_01372 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLLCKODE_01373 9e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLLCKODE_01375 5.7e-175 yfjR K regulation of single-species biofilm formation
HLLCKODE_01377 3.7e-71 S QueT transporter
HLLCKODE_01378 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
HLLCKODE_01380 3.7e-17 yjdB S Domain of unknown function (DUF4767)
HLLCKODE_01381 2.1e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HLLCKODE_01383 8.5e-161 O protein import
HLLCKODE_01384 4.2e-122 agrA KT phosphorelay signal transduction system
HLLCKODE_01385 1.7e-211 2.7.13.3 T protein histidine kinase activity
HLLCKODE_01387 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HLLCKODE_01388 1.5e-36 ylqC L Belongs to the UPF0109 family
HLLCKODE_01389 1e-232 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HLLCKODE_01390 0.0 ydaO E amino acid
HLLCKODE_01391 2.2e-99 folE 3.5.4.16 F gtp cyclohydrolase
HLLCKODE_01392 4.2e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HLLCKODE_01393 4e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HLLCKODE_01394 2.9e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLLCKODE_01395 5.5e-78 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLLCKODE_01396 5.8e-166 murB 1.3.1.98 M cell wall formation
HLLCKODE_01397 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLLCKODE_01398 1.8e-139 potB P ABC-type spermidine putrescine transport system, permease component I
HLLCKODE_01399 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
HLLCKODE_01400 1.7e-204 potD P spermidine putrescine ABC transporter
HLLCKODE_01401 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
HLLCKODE_01402 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
HLLCKODE_01403 2e-158 GK ROK family
HLLCKODE_01404 1.9e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLLCKODE_01405 3.1e-101 wecD M Acetyltransferase (GNAT) domain
HLLCKODE_01406 1.3e-218 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLLCKODE_01407 6.3e-74 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HLLCKODE_01408 1.6e-58 arsC 1.20.4.1 P Belongs to the ArsC family
HLLCKODE_01410 1e-55 lrgA S Effector of murein hydrolase LrgA
HLLCKODE_01411 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLLCKODE_01412 1.2e-97 3.1.3.18 S IA, variant 1
HLLCKODE_01413 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLLCKODE_01414 1.9e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLLCKODE_01415 2.5e-110 serB 3.1.3.3 E phosphoserine phosphatase
HLLCKODE_01416 6.5e-08 N PFAM Uncharacterised protein family UPF0150
HLLCKODE_01417 1.7e-149 EG Permeases of the drug metabolite transporter (DMT) superfamily
HLLCKODE_01419 1.3e-60 ycaO O OsmC-like protein
HLLCKODE_01420 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
HLLCKODE_01421 9.8e-10 O ADP-ribosylglycohydrolase
HLLCKODE_01422 8.1e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLLCKODE_01424 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLLCKODE_01425 1.7e-17 XK27_00735
HLLCKODE_01426 8.7e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HLLCKODE_01427 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HLLCKODE_01428 7.3e-164 S CAAX amino terminal protease family protein
HLLCKODE_01430 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLLCKODE_01431 1.8e-78 mutT 3.6.1.55 F Nudix family
HLLCKODE_01432 2.2e-140 ET ABC transporter
HLLCKODE_01433 6.1e-135 ET Belongs to the bacterial solute-binding protein 3 family
HLLCKODE_01434 3.8e-212 arcT 2.6.1.1 E Aminotransferase
HLLCKODE_01435 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
HLLCKODE_01436 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HLLCKODE_01437 9.9e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLLCKODE_01438 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLLCKODE_01439 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLLCKODE_01440 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HLLCKODE_01441 1.4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HLLCKODE_01442 1.3e-255 S Glucosyl transferase GtrII
HLLCKODE_01443 1.3e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLLCKODE_01444 5.7e-220 amrA S membrane protein involved in the export of O-antigen and teichoic acid
HLLCKODE_01445 3.2e-175 M Glycosyltransferase, group 2 family protein
HLLCKODE_01446 4.4e-180 cpsIaJ S Glycosyltransferase like family 2
HLLCKODE_01447 1.9e-127 arnC M group 2 family protein
HLLCKODE_01448 1.6e-42 S Uncharacterized conserved protein (DUF2304)
HLLCKODE_01449 2.6e-154 2.4.1.60 S Glycosyltransferase group 2 family protein
HLLCKODE_01450 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
HLLCKODE_01451 1.4e-218 M Psort location CytoplasmicMembrane, score
HLLCKODE_01452 8.4e-224 GT4 M transferase activity, transferring glycosyl groups
HLLCKODE_01453 1.4e-220 rgpA GT4 M Domain of unknown function (DUF1972)
HLLCKODE_01454 3.9e-173 rgpB GT2 M Glycosyltransferase, group 2 family protein
HLLCKODE_01455 9.8e-141 rgpC GM Transport permease protein
HLLCKODE_01456 1.8e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HLLCKODE_01457 5.4e-279 rgpF M Rhamnan synthesis protein F
HLLCKODE_01458 5.3e-111 radC E Belongs to the UPF0758 family
HLLCKODE_01459 3.2e-132 puuD T peptidase C26
HLLCKODE_01460 7.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLLCKODE_01461 8.2e-60 XK27_04120 S Putative amino acid metabolism
HLLCKODE_01462 8.3e-207 iscS 2.8.1.7 E Cysteine desulfurase
HLLCKODE_01463 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLLCKODE_01464 6e-100 yjbK S Adenylate cyclase
HLLCKODE_01465 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HLLCKODE_01466 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLLCKODE_01467 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HLLCKODE_01468 8.8e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HLLCKODE_01469 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HLLCKODE_01470 4.1e-310 amiA E ABC transporter, substrate-binding protein, family 5
HLLCKODE_01471 7.8e-277 amiC P ABC transporter (Permease
HLLCKODE_01472 3.8e-165 amiD P ABC transporter (Permease
HLLCKODE_01473 6e-202 oppD P Belongs to the ABC transporter superfamily
HLLCKODE_01474 8e-171 oppF P Belongs to the ABC transporter superfamily
HLLCKODE_01475 3.8e-129 V Psort location CytoplasmicMembrane, score
HLLCKODE_01476 3.1e-119 skfE V abc transporter atp-binding protein
HLLCKODE_01477 5.6e-62 yvoA_1 K Transcriptional
HLLCKODE_01478 1.4e-147 supH S overlaps another CDS with the same product name
HLLCKODE_01479 2.8e-143 XK27_02985 S overlaps another CDS with the same product name
HLLCKODE_01480 4.7e-199 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLLCKODE_01481 1.2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HLLCKODE_01482 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HLLCKODE_01483 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLLCKODE_01484 5.2e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLLCKODE_01485 8.9e-240 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLLCKODE_01486 1.5e-135 stp 3.1.3.16 T phosphatase
HLLCKODE_01487 4.4e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
HLLCKODE_01488 2.1e-100 kcsA P Ion transport protein
HLLCKODE_01489 1.9e-116 yvqF S Membrane
HLLCKODE_01490 9.7e-170 vraS 2.7.13.3 T Histidine kinase
HLLCKODE_01491 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLCKODE_01494 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLLCKODE_01495 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HLLCKODE_01496 3.1e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HLLCKODE_01497 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HLLCKODE_01498 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HLLCKODE_01499 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HLLCKODE_01500 5.8e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HLLCKODE_01501 8.9e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
HLLCKODE_01502 7e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HLLCKODE_01503 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLLCKODE_01504 1.8e-101 2.3.1.128 K Acetyltransferase GNAT Family
HLLCKODE_01505 5.4e-281 S Protein of unknown function (DUF3114)
HLLCKODE_01507 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HLLCKODE_01508 1e-296 V abc transporter atp-binding protein
HLLCKODE_01509 0.0 V abc transporter atp-binding protein
HLLCKODE_01510 1.2e-184 XK27_10075 S abc transporter atp-binding protein
HLLCKODE_01511 3.7e-10
HLLCKODE_01513 1.2e-81 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLLCKODE_01514 0.0 M domain protein
HLLCKODE_01515 1.2e-134 S dextransucrase activity
HLLCKODE_01516 0.0 M Putative cell wall binding repeat
HLLCKODE_01519 4.8e-226 M Putative cell wall binding repeat
HLLCKODE_01522 1.2e-222 L Transposase
HLLCKODE_01523 1e-148 L COG3547 Transposase and inactivated derivatives
HLLCKODE_01525 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
HLLCKODE_01526 7e-58 L thioesterase
HLLCKODE_01527 5.6e-141 S Macro domain protein
HLLCKODE_01528 2.4e-50 trxA O Belongs to the thioredoxin family
HLLCKODE_01529 5.4e-69 yccU S CoA-binding protein
HLLCKODE_01530 5.2e-142 tatD L Hydrolase, tatd
HLLCKODE_01531 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLLCKODE_01532 4.2e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLLCKODE_01534 7.8e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLLCKODE_01535 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HLLCKODE_01536 2e-112 thiN 2.7.6.2 H thiamine pyrophosphokinase
HLLCKODE_01537 1.8e-168 rmuC S RmuC domain protein
HLLCKODE_01538 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
HLLCKODE_01539 6.9e-142 purR 2.4.2.7 F operon repressor
HLLCKODE_01540 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLLCKODE_01541 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLLCKODE_01542 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLLCKODE_01543 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
HLLCKODE_01544 3.4e-113
HLLCKODE_01545 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HLLCKODE_01546 3.7e-85 S Fusaric acid resistance protein-like
HLLCKODE_01547 8.5e-63 glnR K Transcriptional regulator
HLLCKODE_01548 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
HLLCKODE_01549 5.6e-115 pscB M CHAP domain protein
HLLCKODE_01550 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLLCKODE_01551 1.5e-33 ykzG S Belongs to the UPF0356 family
HLLCKODE_01552 1.6e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HLLCKODE_01553 2e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HLLCKODE_01554 3.3e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLLCKODE_01555 3e-114 azlC E AzlC protein
HLLCKODE_01556 3.7e-46 azlD S branched-chain amino acid
HLLCKODE_01557 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLLCKODE_01558 1.1e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HLLCKODE_01559 5.8e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLLCKODE_01560 2.7e-14 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HLLCKODE_01561 1.4e-90 cvpA S toxin biosynthetic process
HLLCKODE_01562 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLLCKODE_01563 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLLCKODE_01565 1.7e-37
HLLCKODE_01566 4.5e-10
HLLCKODE_01568 2.9e-218 mutY L A G-specific adenine glycosylase
HLLCKODE_01569 1.1e-42 XK27_05745
HLLCKODE_01570 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HLLCKODE_01571 6.7e-84 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLLCKODE_01572 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLLCKODE_01574 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
HLLCKODE_01575 6.5e-168 corA P COG0598 Mg2 and Co2 transporters
HLLCKODE_01576 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HLLCKODE_01580 6.1e-32 blpT
HLLCKODE_01582 1.2e-186 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HLLCKODE_01583 1.3e-84 comEB 3.5.4.12 F ComE operon protein 2
HLLCKODE_01584 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLLCKODE_01585 1.7e-61 yqhY S protein conserved in bacteria
HLLCKODE_01586 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLLCKODE_01587 7.5e-180 scrR K Transcriptional regulator
HLLCKODE_01588 4.7e-287 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
HLLCKODE_01589 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HLLCKODE_01590 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HLLCKODE_01591 1.9e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HLLCKODE_01593 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLLCKODE_01594 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HLLCKODE_01595 9.4e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HLLCKODE_01596 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLLCKODE_01597 3.2e-203 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLLCKODE_01598 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLLCKODE_01602 2.9e-31 yozG K Transcriptional regulator
HLLCKODE_01604 3e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HLLCKODE_01605 4e-259 XK27_03190 S hydrolases of the HAD superfamily
HLLCKODE_01606 2.6e-97 yebC M Membrane
HLLCKODE_01607 0.0 KT response to antibiotic
HLLCKODE_01608 7.5e-74 XK27_02470 K LytTr DNA-binding domain protein
HLLCKODE_01609 1.2e-99 liaI S membrane
HLLCKODE_01610 7e-298 O MreB/Mbl protein
HLLCKODE_01612 5.8e-146 V Psort location CytoplasmicMembrane, score
HLLCKODE_01615 2.6e-13
HLLCKODE_01616 3.5e-228 dcuS 2.7.13.3 T protein histidine kinase activity
HLLCKODE_01617 4.9e-233 2.7.13.3 T protein histidine kinase activity
HLLCKODE_01618 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HLLCKODE_01619 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HLLCKODE_01620 6.3e-118 S Protein of unknown function (DUF554)
HLLCKODE_01621 8.1e-134 ecsA_2 V abc transporter atp-binding protein
HLLCKODE_01622 9.8e-286 XK27_00765
HLLCKODE_01623 1.1e-139 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLLCKODE_01624 6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLLCKODE_01625 9.2e-60 yhaI J Membrane
HLLCKODE_01626 3.8e-61 yhaI J Protein of unknown function (DUF805)
HLLCKODE_01627 2.7e-43 yhaI J Protein of unknown function (DUF805)
HLLCKODE_01629 8.1e-95
HLLCKODE_01630 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLLCKODE_01631 2.4e-45 ftsL D cell division protein FtsL
HLLCKODE_01632 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HLLCKODE_01633 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLLCKODE_01634 9.8e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLLCKODE_01637 3.1e-259 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HLLCKODE_01638 5.6e-63 yutD J protein conserved in bacteria
HLLCKODE_01639 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HLLCKODE_01640 6.3e-88 XK27_09885 V Glycopeptide antibiotics resistance protein
HLLCKODE_01642 0.0 mdlA V abc transporter atp-binding protein
HLLCKODE_01643 0.0 mdlB V abc transporter atp-binding protein
HLLCKODE_01650 1.8e-44 spiA K sequence-specific DNA binding
HLLCKODE_01651 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLLCKODE_01652 2.5e-158 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HLLCKODE_01653 5.5e-97 V CAAX protease self-immunity
HLLCKODE_01654 3.5e-140 cppA E CppA N-terminal
HLLCKODE_01655 6.7e-173 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HLLCKODE_01657 4.9e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLCKODE_01658 1.2e-140 cah 4.2.1.1 P carbonic anhydrase
HLLCKODE_01659 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HLLCKODE_01660 1.2e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLLCKODE_01661 1e-34
HLLCKODE_01662 9.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HLLCKODE_01663 5.2e-162 yxeN P ABC transporter (Permease
HLLCKODE_01664 3.6e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
HLLCKODE_01665 5e-10 S Protein of unknown function (DUF4059)
HLLCKODE_01666 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLLCKODE_01667 2.1e-91 rsmD 2.1.1.171 L Methyltransferase
HLLCKODE_01668 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLLCKODE_01669 1.1e-187 ylbL T Belongs to the peptidase S16 family
HLLCKODE_01670 2.7e-182 yhcC S radical SAM protein
HLLCKODE_01671 9.4e-95 ytqB 2.1.1.176 J (SAM)-dependent
HLLCKODE_01673 0.0 yjcE P NhaP-type Na H and K H antiporters
HLLCKODE_01674 1.5e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HLLCKODE_01675 1.9e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HLLCKODE_01676 6.2e-09 MU outer membrane autotransporter barrel domain protein
HLLCKODE_01677 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLLCKODE_01679 1.2e-74 XK27_03180 T universal stress protein
HLLCKODE_01680 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HLLCKODE_01681 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HLLCKODE_01682 4.4e-100 pncA Q isochorismatase
HLLCKODE_01683 6.4e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HLLCKODE_01684 6.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HLLCKODE_01685 6.3e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
HLLCKODE_01686 1.1e-189 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HLLCKODE_01687 5.8e-232 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HLLCKODE_01688 5.3e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLLCKODE_01689 2.5e-267 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLLCKODE_01690 6.6e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLLCKODE_01691 8.1e-88 tag 3.2.2.20 L glycosylase
HLLCKODE_01692 4.9e-41 S Sugar efflux transporter for intercellular exchange
HLLCKODE_01693 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HLLCKODE_01694 7.1e-227 rodA D Belongs to the SEDS family
HLLCKODE_01695 3.5e-244 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLLCKODE_01696 2.6e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HLLCKODE_01697 4.6e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLLCKODE_01698 4.3e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLCKODE_01699 3.2e-127 Q Methyltransferase domain
HLLCKODE_01700 1.2e-65 GnaT 2.5.1.16 K acetyltransferase
HLLCKODE_01701 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HLLCKODE_01702 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLLCKODE_01703 1.8e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HLLCKODE_01704 1.3e-125 dnaD
HLLCKODE_01705 1.3e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLLCKODE_01707 6.2e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLLCKODE_01708 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLLCKODE_01709 5.2e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLLCKODE_01710 1.5e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HLLCKODE_01711 2.8e-73 argR K Regulates arginine biosynthesis genes
HLLCKODE_01712 5.6e-300 recN L May be involved in recombinational repair of damaged DNA
HLLCKODE_01713 1.5e-144 DegV S DegV family
HLLCKODE_01714 3.1e-156 ypmR E COG2755 Lysophospholipase L1 and related esterases
HLLCKODE_01715 3.4e-95 ypmS S Protein conserved in bacteria
HLLCKODE_01716 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLLCKODE_01718 1.4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HLLCKODE_01719 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLLCKODE_01720 5.4e-53 hxlR K HxlR-like helix-turn-helix
HLLCKODE_01721 2e-70 S SnoaL-like polyketide cyclase
HLLCKODE_01722 2.1e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HLLCKODE_01723 2.3e-187 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HLLCKODE_01724 4.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLLCKODE_01725 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLLCKODE_01726 1.8e-221 L the current gene model (or a revised gene model) may contain a frame shift
HLLCKODE_01727 5.9e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HLLCKODE_01728 2.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
HLLCKODE_01729 4.6e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HLLCKODE_01730 2.3e-190 tcsA S membrane
HLLCKODE_01731 1.3e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HLLCKODE_01732 1.8e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLLCKODE_01733 1.3e-227 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HLLCKODE_01734 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
HLLCKODE_01735 2.8e-171 coaA 2.7.1.33 F Pantothenic acid kinase
HLLCKODE_01736 1e-29 rpsT J Binds directly to 16S ribosomal RNA
HLLCKODE_01737 1.3e-241 T PhoQ Sensor
HLLCKODE_01738 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLCKODE_01739 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HLLCKODE_01740 4.6e-115 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HLLCKODE_01741 9.7e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLLCKODE_01742 3.9e-91 panT S ECF transporter, substrate-specific component
HLLCKODE_01743 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HLLCKODE_01744 1.6e-165 metF 1.5.1.20 E reductase
HLLCKODE_01745 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLLCKODE_01747 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HLLCKODE_01748 0.0 3.6.3.8 P cation transport ATPase
HLLCKODE_01749 1.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLLCKODE_01750 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLCKODE_01751 1.2e-235 dltB M Membrane protein involved in D-alanine export
HLLCKODE_01752 4.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLCKODE_01753 0.0 XK27_10035 V abc transporter atp-binding protein
HLLCKODE_01754 1.4e-213 yfiB1 V abc transporter atp-binding protein
HLLCKODE_01755 1.6e-68 yfiB1 V abc transporter atp-binding protein
HLLCKODE_01756 5.4e-99 pvaA M lytic transglycosylase activity
HLLCKODE_01757 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
HLLCKODE_01758 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLLCKODE_01759 1.9e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLLCKODE_01760 2.3e-140 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLLCKODE_01761 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLLCKODE_01762 1.9e-109 tdk 2.7.1.21 F thymidine kinase
HLLCKODE_01763 1.3e-182 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HLLCKODE_01764 3.5e-151 gst O Glutathione S-transferase
HLLCKODE_01765 9.3e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HLLCKODE_01766 1.9e-172 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLLCKODE_01767 4.4e-45 rpmE2 J 50S ribosomal protein L31
HLLCKODE_01768 7.9e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
HLLCKODE_01769 7.9e-161 ypuA S secreted protein
HLLCKODE_01770 8.2e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
HLLCKODE_01771 3.9e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HLLCKODE_01772 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLLCKODE_01773 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HLLCKODE_01774 2.1e-252 noxE P NADH oxidase
HLLCKODE_01775 1.9e-294 yfmM S abc transporter atp-binding protein
HLLCKODE_01776 5.4e-79 XK27_01265 S ECF-type riboflavin transporter, S component
HLLCKODE_01777 8.8e-148 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HLLCKODE_01778 1.6e-83 S ECF-type riboflavin transporter, S component
HLLCKODE_01780 4.4e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLLCKODE_01781 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HLLCKODE_01783 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLLCKODE_01784 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLCKODE_01785 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLLCKODE_01786 7.3e-20 WQ51_00220 K Helix-turn-helix domain
HLLCKODE_01787 5.9e-89 S Protein of unknown function (DUF3278)
HLLCKODE_01788 0.0 smc D Required for chromosome condensation and partitioning
HLLCKODE_01789 9.3e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLLCKODE_01790 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLLCKODE_01791 2.8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLLCKODE_01792 8.8e-124 alkD L DNA alkylation repair enzyme
HLLCKODE_01793 9.1e-292 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLLCKODE_01794 6.3e-93 pat 2.3.1.183 M acetyltransferase
HLLCKODE_01795 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLLCKODE_01796 1.8e-279 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HLLCKODE_01797 3.4e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HLLCKODE_01798 4.6e-45 L RePlication protein
HLLCKODE_01799 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLLCKODE_01800 5.5e-124 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HLLCKODE_01801 3e-119 sdaAB 4.3.1.17 E L-serine dehydratase
HLLCKODE_01802 2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
HLLCKODE_01803 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
HLLCKODE_01804 1.9e-133 L Integrase
HLLCKODE_01805 2e-202 S Protein of unknown function DUF262
HLLCKODE_01806 2.7e-151 S Protein of unknown function DUF262
HLLCKODE_01807 3.8e-78 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HLLCKODE_01808 4e-79 3.4.21.89 S RDD family
HLLCKODE_01809 4.2e-164 K sequence-specific DNA binding
HLLCKODE_01810 8.9e-153 V ABC transporter, ATP-binding protein
HLLCKODE_01811 1.7e-96 S ABC-2 family transporter protein
HLLCKODE_01812 1.1e-151 K sequence-specific DNA binding
HLLCKODE_01813 1e-50 ywrO S general stress protein
HLLCKODE_01814 8.4e-142 L PFAM transposase IS116 IS110 IS902 family
HLLCKODE_01815 7.2e-65 L Transposase (IS116 IS110 IS902 family)
HLLCKODE_01816 2.6e-09
HLLCKODE_01818 8.4e-166 yeiH S Membrane
HLLCKODE_01819 1.3e-123 mur1 3.4.17.14, 3.5.1.28 NU muramidase
HLLCKODE_01820 7.6e-166 cpsY K Transcriptional regulator
HLLCKODE_01821 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLLCKODE_01822 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
HLLCKODE_01823 3.1e-105 artQ P ABC transporter (Permease
HLLCKODE_01824 2e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
HLLCKODE_01825 6.7e-156 aatB ET ABC transporter substrate-binding protein
HLLCKODE_01826 2.6e-266 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLLCKODE_01827 1.2e-48
HLLCKODE_01828 1.3e-44
HLLCKODE_01829 4.6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
HLLCKODE_01830 6.7e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLLCKODE_01831 1.9e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HLLCKODE_01832 3.5e-126 gntR1 K transcriptional
HLLCKODE_01833 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLLCKODE_01834 2.9e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLLCKODE_01835 2e-86
HLLCKODE_01836 7e-92 niaR S small molecule binding protein (contains 3H domain)
HLLCKODE_01837 1.6e-128 K DNA-binding helix-turn-helix protein
HLLCKODE_01838 6.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLLCKODE_01839 3.4e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLLCKODE_01840 9.4e-156 GK ROK family
HLLCKODE_01841 2.1e-154 dprA LU DNA protecting protein DprA
HLLCKODE_01842 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLLCKODE_01843 5.3e-150 S TraX protein
HLLCKODE_01844 2.3e-119 KT Transcriptional regulatory protein, C terminal
HLLCKODE_01845 3.1e-235 T PhoQ Sensor
HLLCKODE_01846 1.2e-255 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLLCKODE_01847 8.8e-220 XK27_05470 E Methionine synthase
HLLCKODE_01848 1e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HLLCKODE_01849 1.1e-44 pspE P Rhodanese-like protein
HLLCKODE_01850 2.4e-136 IQ Acetoin reductase
HLLCKODE_01852 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLLCKODE_01855 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HLLCKODE_01856 3.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HLLCKODE_01857 3.2e-64 mgrA K Transcriptional regulator, MarR family
HLLCKODE_01858 4.6e-124 S SnoaL-like domain
HLLCKODE_01859 1.6e-150 C alcohol dehydrogenase
HLLCKODE_01860 2.8e-126 proV E abc transporter atp-binding protein
HLLCKODE_01861 1.2e-261 proWX P ABC transporter
HLLCKODE_01862 5.3e-139 S Phenazine biosynthesis protein
HLLCKODE_01863 9.1e-91 2.7.7.65 T Psort location CytoplasmicMembrane, score
HLLCKODE_01864 3.7e-132 cbiQ P cobalt transport
HLLCKODE_01865 4.5e-157 P ATPase activity
HLLCKODE_01866 1.8e-150 cbiO2 P ABC transporter, ATP-binding protein
HLLCKODE_01867 2.9e-63 pnuC H nicotinamide mononucleotide transporter
HLLCKODE_01868 2.5e-66 K Transcriptional regulator
HLLCKODE_01869 1.5e-176 1.1.1.1 C nadph quinone reductase
HLLCKODE_01870 8.9e-153 I Alpha/beta hydrolase family
HLLCKODE_01871 2.1e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLCKODE_01872 8.1e-41
HLLCKODE_01873 3.7e-55 S Protein of unknown function with HXXEE motif
HLLCKODE_01874 5.1e-99 K Transcriptional regulator, TetR family
HLLCKODE_01875 5e-154 czcD P cation diffusion facilitator family transporter
HLLCKODE_01876 6.7e-193 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HLLCKODE_01877 2.3e-187 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HLLCKODE_01878 1.3e-135 G protein with an alpha beta hydrolase fold
HLLCKODE_01881 3.5e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HLLCKODE_01882 0.0 V Type III restriction enzyme, res subunit
HLLCKODE_01883 2.1e-49 S von Willebrand factor (vWF) type A domain
HLLCKODE_01884 2.1e-174 yclQ P ABC-type enterochelin transport system, periplasmic component
HLLCKODE_01885 3.7e-233 dinF V Mate efflux family protein
HLLCKODE_01886 6.2e-277 S Psort location CytoplasmicMembrane, score
HLLCKODE_01887 2.8e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HLLCKODE_01888 1.4e-134 S TraX protein
HLLCKODE_01889 2e-92 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HLLCKODE_01890 1.5e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HLLCKODE_01891 9.4e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLLCKODE_01892 2.7e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLLCKODE_01893 1.6e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLLCKODE_01894 4.1e-130 cas6 S Pfam:DUF2276
HLLCKODE_01895 0.0 csm1 S CRISPR-associated protein Csm1 family
HLLCKODE_01896 2e-38 csm2 L Csm2 Type III-A
HLLCKODE_01897 1.4e-113 csm3 L RAMP superfamily
HLLCKODE_01898 2.3e-162 csm4 L CRISPR-associated RAMP protein, Csm4 family
HLLCKODE_01899 1.3e-204 csm5 L CRISPR-associated RAMP protein, Csm5 family
HLLCKODE_01900 6.8e-111 csm6 S Psort location Cytoplasmic, score
HLLCKODE_01901 4.5e-148 csm6 S Psort location Cytoplasmic, score
HLLCKODE_01902 8.5e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLLCKODE_01903 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLLCKODE_01904 1.1e-243 nylA 3.5.1.4 J Belongs to the amidase family
HLLCKODE_01905 4.6e-149 yckB ET Belongs to the bacterial solute-binding protein 3 family
HLLCKODE_01906 9.3e-81 yecS P ABC transporter (Permease
HLLCKODE_01907 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HLLCKODE_01908 4.6e-169 bglC K Transcriptional regulator
HLLCKODE_01909 1.8e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLLCKODE_01910 2.2e-238 agcS E (Alanine) symporter
HLLCKODE_01911 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HLLCKODE_01912 4.3e-239 metY 2.5.1.49 E o-acetylhomoserine
HLLCKODE_01913 1.8e-136 S haloacid dehalogenase-like hydrolase
HLLCKODE_01914 6.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLLCKODE_01915 2.1e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HLLCKODE_01916 8e-35 M1-755 P Hemerythrin HHE cation binding domain protein
HLLCKODE_01917 1e-235 XK27_04775 S hemerythrin HHE cation binding domain
HLLCKODE_01918 1.2e-144 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLLCKODE_01919 1.1e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HLLCKODE_01920 7.9e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLLCKODE_01921 5.1e-44 yktA S Belongs to the UPF0223 family
HLLCKODE_01922 3.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HLLCKODE_01923 9.1e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HLLCKODE_01924 2.6e-155 pstS P phosphate
HLLCKODE_01925 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HLLCKODE_01926 9.1e-156 pstA P phosphate transport system permease
HLLCKODE_01927 1.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLLCKODE_01928 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLLCKODE_01929 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
HLLCKODE_01930 0.0 pepN 3.4.11.2 E aminopeptidase
HLLCKODE_01931 1.6e-191 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HLLCKODE_01932 3.6e-185 lplA 6.3.1.20 H Lipoate-protein ligase
HLLCKODE_01933 2.8e-37
HLLCKODE_01934 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLLCKODE_01935 2.8e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HLLCKODE_01936 4.5e-172 malR K Transcriptional regulator
HLLCKODE_01937 3.9e-229 malX G ABC transporter
HLLCKODE_01938 5.7e-250 malF P ABC transporter (Permease
HLLCKODE_01939 9.8e-152 malG P ABC transporter (Permease
HLLCKODE_01940 8.8e-212 msmX P Belongs to the ABC transporter superfamily
HLLCKODE_01941 1.9e-23 tatA U protein secretion
HLLCKODE_01942 1.3e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLLCKODE_01943 9.7e-292 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HLLCKODE_01944 2.2e-229 ycdB P peroxidase
HLLCKODE_01945 1.2e-144 ycdO P periplasmic lipoprotein involved in iron transport
HLLCKODE_01946 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HLLCKODE_01948 1.5e-177 yegQ O Peptidase U32
HLLCKODE_01949 1.7e-251 yegQ O Peptidase U32
HLLCKODE_01950 1.3e-85 bioY S biotin synthase
HLLCKODE_01952 1.1e-33 XK27_12190 S protein conserved in bacteria
HLLCKODE_01953 4.8e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HLLCKODE_01954 2.8e-11
HLLCKODE_01955 1.6e-14
HLLCKODE_01956 5.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HLLCKODE_01957 2.9e-134 M LysM domain
HLLCKODE_01958 8.4e-23
HLLCKODE_01959 1.5e-174 S hydrolase
HLLCKODE_01961 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HLLCKODE_01962 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLLCKODE_01963 3.6e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HLLCKODE_01964 1.5e-25 P Hemerythrin HHE cation binding domain protein
HLLCKODE_01965 8.3e-137 5.2.1.8 G hydrolase
HLLCKODE_01966 2.6e-112 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLLCKODE_01967 1.7e-194 MA20_36090 S Protein of unknown function (DUF2974)
HLLCKODE_01968 1.9e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLCKODE_01969 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
HLLCKODE_01970 1.1e-271 hsdM 2.1.1.72 V N-6 DNA Methylase
HLLCKODE_01971 2.4e-151 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HLLCKODE_01972 4.6e-93
HLLCKODE_01973 3.5e-164
HLLCKODE_01974 3.4e-189 higA K Pfam:DUF955
HLLCKODE_01975 1.7e-133 S PD-(D/E)XK nuclease family transposase
HLLCKODE_01977 0.0 2.4.1.21 GT5 M Right handed beta helix region
HLLCKODE_01978 3.5e-29 2.4.1.21 GT5 M Right handed beta helix region
HLLCKODE_01979 4.3e-170 spd F DNA RNA non-specific endonuclease
HLLCKODE_01980 1.1e-90 lemA S LemA family
HLLCKODE_01981 3.4e-134 htpX O Belongs to the peptidase M48B family
HLLCKODE_01982 9.1e-113 sirR K iron dependent repressor
HLLCKODE_01983 3.3e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
HLLCKODE_01984 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
HLLCKODE_01985 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
HLLCKODE_01986 2.1e-74 S Psort location CytoplasmicMembrane, score
HLLCKODE_01987 2.1e-64 S Domain of unknown function (DUF4430)
HLLCKODE_01988 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HLLCKODE_01989 1.6e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
HLLCKODE_01990 2.7e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HLLCKODE_01991 2.9e-164 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HLLCKODE_01992 1.6e-101 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HLLCKODE_01993 2.4e-79 dps P Belongs to the Dps family
HLLCKODE_01994 3.4e-79 perR P Belongs to the Fur family
HLLCKODE_01995 4.2e-27 yqgQ S protein conserved in bacteria
HLLCKODE_01996 1.1e-175 glk 2.7.1.2 G Glucokinase
HLLCKODE_01997 0.0 typA T GTP-binding protein TypA
HLLCKODE_01999 1.5e-247 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLLCKODE_02000 4.4e-197 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLLCKODE_02001 2.3e-135 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLLCKODE_02002 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLLCKODE_02003 3.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLLCKODE_02004 6.2e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLLCKODE_02005 3.4e-90 sepF D cell septum assembly
HLLCKODE_02006 3.5e-31 yggT D integral membrane protein
HLLCKODE_02007 2.3e-137 ylmH S conserved protein, contains S4-like domain
HLLCKODE_02008 5.5e-137 divIVA D Cell division initiation protein
HLLCKODE_02009 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLLCKODE_02010 8.5e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLLCKODE_02011 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLLCKODE_02012 6.5e-34 nrdH O Glutaredoxin
HLLCKODE_02013 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HLLCKODE_02014 2.6e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
HLLCKODE_02015 5.9e-219 icd 1.1.1.42 C Isocitrate dehydrogenase
HLLCKODE_02016 3e-38 ptsH G phosphocarrier protein Hpr
HLLCKODE_02017 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLLCKODE_02018 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HLLCKODE_02019 4.3e-160 XK27_05670 S Putative esterase
HLLCKODE_02020 2.7e-153 XK27_05675 S Esterase
HLLCKODE_02021 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
HLLCKODE_02022 6e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
HLLCKODE_02023 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HLLCKODE_02024 0.0 uup S abc transporter atp-binding protein
HLLCKODE_02025 2.7e-39 MA20_06245 S yiaA/B two helix domain
HLLCKODE_02026 9.7e-132 pip 1.11.1.10 S Alpha beta hydrolase
HLLCKODE_02027 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLLCKODE_02028 8.1e-148 cobQ S glutamine amidotransferase
HLLCKODE_02029 8.4e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HLLCKODE_02030 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLLCKODE_02031 3.2e-162 ybbR S Protein conserved in bacteria
HLLCKODE_02032 3.7e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLLCKODE_02033 1.8e-66 gtrA S GtrA-like protein
HLLCKODE_02034 3.7e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
HLLCKODE_02035 1.3e-142 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLLCKODE_02036 1.1e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
HLLCKODE_02037 5.1e-193 yurR 1.4.5.1 E oxidoreductase
HLLCKODE_02038 9e-256 S phospholipase Carboxylesterase
HLLCKODE_02039 3.2e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLLCKODE_02040 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLLCKODE_02041 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLLCKODE_02044 5.7e-31 KT response to antibiotic
HLLCKODE_02045 2.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
HLLCKODE_02046 4.8e-110 fat 3.1.2.21 I Acyl-ACP thioesterase
HLLCKODE_02047 2.5e-32 S TIR domain
HLLCKODE_02048 1.6e-135 nagD 2.7.1.25, 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HLLCKODE_02049 1.1e-113 ylfI S tigr01906
HLLCKODE_02050 3.3e-135 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HLLCKODE_02051 5.2e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HLLCKODE_02052 8.6e-58 XK27_08085
HLLCKODE_02053 3.6e-191 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLLCKODE_02054 7.2e-178 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLLCKODE_02055 5.2e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HLLCKODE_02056 7.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLLCKODE_02057 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HLLCKODE_02058 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLLCKODE_02059 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HLLCKODE_02060 2.8e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLLCKODE_02061 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HLLCKODE_02062 6.9e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HLLCKODE_02064 6.5e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
HLLCKODE_02065 1.4e-144 P molecular chaperone
HLLCKODE_02066 1.4e-104 S Carbohydrate-binding domain-containing protein Cthe_2159
HLLCKODE_02067 7.5e-178 XK27_08075 M glycosyl transferase family 2
HLLCKODE_02068 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HLLCKODE_02069 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HLLCKODE_02071 8.3e-17 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLLCKODE_02072 1.8e-122 atpB C it plays a direct role in the translocation of protons across the membrane
HLLCKODE_02073 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLLCKODE_02074 2.3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLLCKODE_02075 5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLLCKODE_02076 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLLCKODE_02077 6.7e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLLCKODE_02078 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HLLCKODE_02079 6e-217 ftsW D Belongs to the SEDS family
HLLCKODE_02080 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLLCKODE_02081 5.8e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLLCKODE_02082 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLLCKODE_02084 2.9e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLLCKODE_02085 1.7e-159 holB 2.7.7.7 L dna polymerase iii
HLLCKODE_02086 5.8e-133 yaaT S stage 0 sporulation protein
HLLCKODE_02087 1.2e-54 yabA L Involved in initiation control of chromosome replication
HLLCKODE_02088 3.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLLCKODE_02089 8.7e-26 amt P Ammonium Transporter
HLLCKODE_02090 4.6e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
HLLCKODE_02091 5.9e-141 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HLLCKODE_02092 5.4e-76 S Bacterial inner membrane protein
HLLCKODE_02093 1.4e-113 3.4.17.14, 3.5.1.28 NU amidase activity
HLLCKODE_02094 3.5e-294 nptA P COG1283 Na phosphate symporter
HLLCKODE_02095 2e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLLCKODE_02096 1e-221 S membrane
HLLCKODE_02097 6.3e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HLLCKODE_02098 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HLLCKODE_02099 1.7e-38 ynzC S UPF0291 protein
HLLCKODE_02100 4.8e-252 cycA E permease
HLLCKODE_02101 6.4e-10 uvrX 2.7.7.7 L impB/mucB/samB family
HLLCKODE_02102 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HLLCKODE_02103 3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLLCKODE_02107 3.9e-154 V AAA domain, putative AbiEii toxin, Type IV TA system
HLLCKODE_02108 2.4e-56 S ABC-2 type transporter
HLLCKODE_02109 8.2e-97
HLLCKODE_02111 1.2e-166 fhuR K transcriptional regulator (lysR family)
HLLCKODE_02112 2.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLLCKODE_02113 1.6e-160 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLLCKODE_02114 1.8e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLLCKODE_02115 4.9e-219 pyrP F uracil Permease
HLLCKODE_02116 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HLLCKODE_02117 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HLLCKODE_02118 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HLLCKODE_02119 6.6e-123 rsmJ 2.1.1.242 J Putative SAM-dependent methyltransferase
HLLCKODE_02120 6.8e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLLCKODE_02121 2e-121 macB V ABC transporter, ATP-binding protein
HLLCKODE_02122 3.8e-213 V permease protein
HLLCKODE_02123 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLLCKODE_02124 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLLCKODE_02125 3e-21 XK27_00530 M CHAP domain protein
HLLCKODE_02126 1.7e-102 abiGI K Transcriptional regulator, AbiEi antitoxin
HLLCKODE_02127 2.7e-272 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HLLCKODE_02128 2.4e-18 K DNA-binding transcription factor activity
HLLCKODE_02129 0.0 mdlB V abc transporter atp-binding protein
HLLCKODE_02130 0.0 lmrA V abc transporter atp-binding protein
HLLCKODE_02131 6.6e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLLCKODE_02132 8.9e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLLCKODE_02133 6.9e-213 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HLLCKODE_02134 1.3e-128 rr02 KT response regulator
HLLCKODE_02135 1.7e-114 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLLCKODE_02136 5.7e-51 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLLCKODE_02137 4.8e-168 V ABC transporter
HLLCKODE_02138 5.4e-122 sagI S ABC-2 type transporter
HLLCKODE_02139 6.9e-197 yceA S Belongs to the UPF0176 family
HLLCKODE_02140 1.6e-28 XK27_00085 K Transcriptional
HLLCKODE_02141 2.3e-23
HLLCKODE_02142 9.1e-136 deoD_1 2.4.2.3 F Phosphorylase superfamily
HLLCKODE_02143 1.5e-113 S VIT family
HLLCKODE_02144 6.5e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLLCKODE_02145 5e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HLLCKODE_02146 2.1e-197 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HLLCKODE_02148 1e-126 E Alpha beta hydrolase
HLLCKODE_02149 6.3e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HLLCKODE_02150 1.8e-101 GBS0088 J protein conserved in bacteria
HLLCKODE_02151 8.5e-146 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HLLCKODE_02152 1.2e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HLLCKODE_02153 5.1e-163 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HLLCKODE_02154 2.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLLCKODE_02155 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HLLCKODE_02156 1.1e-227 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLLCKODE_02157 6.5e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HLLCKODE_02158 7.3e-21
HLLCKODE_02159 2.2e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLLCKODE_02160 0.0 U protein secretion
HLLCKODE_02161 9.8e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HLLCKODE_02162 4.5e-244 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HLLCKODE_02163 4e-53 XK27_13030
HLLCKODE_02164 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLLCKODE_02165 1.3e-144 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLLCKODE_02166 2.6e-194 S Protein of unknown function (DUF3114)
HLLCKODE_02167 4.1e-29 pspC KT PspC domain protein
HLLCKODE_02168 4.4e-118 yqfA K protein, Hemolysin III
HLLCKODE_02169 5e-78 K hmm pf08876
HLLCKODE_02170 2.5e-223 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HLLCKODE_02171 1e-210 mvaS 2.3.3.10 I synthase
HLLCKODE_02172 2.1e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLLCKODE_02173 1.9e-89 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLLCKODE_02174 9.7e-22
HLLCKODE_02175 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLLCKODE_02176 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HLLCKODE_02177 1.8e-15 mmuP E amino acid
HLLCKODE_02178 4.3e-217 mmuP E amino acid
HLLCKODE_02179 5.5e-167 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HLLCKODE_02180 2.2e-30 S Domain of unknown function (DUF1912)
HLLCKODE_02181 4e-12 L Helix-hairpin-helix DNA-binding motif class 1
HLLCKODE_02182 1.9e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLLCKODE_02183 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLLCKODE_02185 1e-08
HLLCKODE_02186 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLLCKODE_02187 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HLLCKODE_02188 3.7e-16 S Protein of unknown function (DUF2969)
HLLCKODE_02191 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
HLLCKODE_02192 9.5e-21 L Transposase
HLLCKODE_02194 3.4e-43 L Transposase
HLLCKODE_02195 8.2e-22 L IS861 transposase
HLLCKODE_02196 1.9e-126 L Transposase and inactivated derivatives
HLLCKODE_02197 3.9e-202 L Transposase IS116 IS110 IS902
HLLCKODE_02198 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
HLLCKODE_02199 5e-16 S HipA-like C-terminal domain
HLLCKODE_02201 1.4e-58 S PcfJ-like protein
HLLCKODE_02202 1.8e-12 S PcfK-like protein
HLLCKODE_02203 2.3e-38 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLLCKODE_02204 3.3e-17
HLLCKODE_02205 1.1e-72 S Region found in RelA / SpoT proteins
HLLCKODE_02206 4.9e-28 dnaG L DNA primase activity
HLLCKODE_02207 5.4e-25 soj D ATPases involved in chromosome partitioning
HLLCKODE_02209 8e-08 L Psort location Cytoplasmic, score 8.96
HLLCKODE_02210 5.6e-21 xerS L Belongs to the 'phage' integrase family
HLLCKODE_02211 5.6e-52 spd F DNA RNA non-specific endonuclease
HLLCKODE_02213 1.7e-230 2.7.13.3 T GHKL domain
HLLCKODE_02214 5.3e-133 agrA KT Response regulator of the LytR AlgR family
HLLCKODE_02217 2.5e-96 L Transposase and inactivated derivatives
HLLCKODE_02218 1e-37 L Transposase and inactivated derivatives
HLLCKODE_02219 6.9e-104 ubiE Q Methyltransferase
HLLCKODE_02220 3.7e-20 S Ribosomal protein S1-like RNA-binding domain
HLLCKODE_02222 2.7e-127 U TraM recognition site of TraD and TraG
HLLCKODE_02223 4.8e-97 S HD domain
HLLCKODE_02230 4.8e-172 S there are four paralogs in L.lactis
HLLCKODE_02231 3.4e-46
HLLCKODE_02233 2.7e-99
HLLCKODE_02234 2.7e-15 L Transposase, IS605 OrfB family
HLLCKODE_02238 1.4e-32 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLLCKODE_02239 1.1e-65 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HLLCKODE_02240 1.3e-09 S ERF superfamily
HLLCKODE_02245 1.3e-29 radC E Belongs to the UPF0758 family
HLLCKODE_02253 3.5e-103 abiGI K Transcriptional regulator, AbiEi antitoxin
HLLCKODE_02255 1.9e-81 FNV0100 F Belongs to the Nudix hydrolase family
HLLCKODE_02256 4.5e-71 XK27_01300 P Protein conserved in bacteria
HLLCKODE_02259 1.3e-196 T PhoQ Sensor
HLLCKODE_02260 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLCKODE_02261 6.9e-167 bcrA V abc transporter atp-binding protein
HLLCKODE_02262 1.1e-130 S ABC-2 family transporter protein
HLLCKODE_02263 1.5e-124 S ABC-2 family transporter protein
HLLCKODE_02264 1.1e-62 S pathogenesis
HLLCKODE_02266 1.4e-75 mutT 3.6.1.13, 3.6.1.55, 3.6.1.56, 3.6.1.62, 3.6.1.64 F Nudix family
HLLCKODE_02267 2.6e-117 K Psort location Cytoplasmic, score
HLLCKODE_02268 1.3e-218 S AAA domain
HLLCKODE_02269 8.9e-10 S Protein of unknown function (DUF2975)
HLLCKODE_02270 3.3e-22 yozG K Transcriptional regulator
HLLCKODE_02271 7.2e-08
HLLCKODE_02273 3.2e-145 L Integrase core domain protein
HLLCKODE_02274 1.6e-123 L Helix-turn-helix domain
HLLCKODE_02277 6.2e-85 MA20_25245 K Acetyltransferase (GNAT) domain
HLLCKODE_02278 1.8e-44
HLLCKODE_02281 2.2e-130 clpB O C-terminal, D2-small domain, of ClpB protein
HLLCKODE_02283 5.2e-45
HLLCKODE_02284 9.6e-53 I mechanosensitive ion channel activity
HLLCKODE_02285 9.8e-161 K sequence-specific DNA binding
HLLCKODE_02286 7.7e-09

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)