ORF_ID e_value Gene_name EC_number CAZy COGs Description
LEHHPAIP_00001 4.3e-13
LEHHPAIP_00002 1.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
LEHHPAIP_00003 5.7e-85 ltrA S Bacterial low temperature requirement A protein (LtrA)
LEHHPAIP_00005 4.9e-80 KT Purine catabolism regulatory protein-like family
LEHHPAIP_00006 5.5e-154 F Permease for cytosine/purines, uracil, thiamine, allantoin
LEHHPAIP_00007 5.2e-153 S Protein of unknown function (DUF917)
LEHHPAIP_00008 1.8e-183 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
LEHHPAIP_00009 2.7e-236 G MFS/sugar transport protein
LEHHPAIP_00010 5.9e-11
LEHHPAIP_00013 1.6e-85 S MobA/MobL family
LEHHPAIP_00017 1.1e-113 S (CBS) domain
LEHHPAIP_00018 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEHHPAIP_00019 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEHHPAIP_00020 2.1e-39 yabO J S4 domain protein
LEHHPAIP_00021 5.6e-56 divIC D Septum formation initiator
LEHHPAIP_00022 9.8e-67 yabR J RNA binding
LEHHPAIP_00023 1.2e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEHHPAIP_00024 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LEHHPAIP_00025 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEHHPAIP_00026 2.6e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEHHPAIP_00027 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEHHPAIP_00028 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LEHHPAIP_00029 9.4e-118 L Integrase
LEHHPAIP_00030 3e-156 rssA S Phospholipase, patatin family
LEHHPAIP_00031 1.6e-53 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
LEHHPAIP_00032 6.7e-164 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
LEHHPAIP_00033 5.8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
LEHHPAIP_00034 1.3e-201 xerS L Belongs to the 'phage' integrase family
LEHHPAIP_00036 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEHHPAIP_00037 1.2e-76 marR K Transcriptional regulator, MarR family
LEHHPAIP_00038 7.9e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEHHPAIP_00039 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEHHPAIP_00040 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LEHHPAIP_00041 1.2e-124 IQ reductase
LEHHPAIP_00042 4.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEHHPAIP_00043 2.9e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEHHPAIP_00044 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEHHPAIP_00045 7e-256 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
LEHHPAIP_00046 4.2e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEHHPAIP_00047 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
LEHHPAIP_00048 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LEHHPAIP_00075 2.1e-24
LEHHPAIP_00076 9.5e-59
LEHHPAIP_00077 1.3e-70
LEHHPAIP_00078 9.3e-32
LEHHPAIP_00079 9.8e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LEHHPAIP_00080 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEHHPAIP_00081 2e-100 fic D Fic/DOC family
LEHHPAIP_00082 2.8e-70
LEHHPAIP_00083 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
LEHHPAIP_00084 2.1e-88 L nuclease
LEHHPAIP_00085 2.7e-39
LEHHPAIP_00086 0.0 ydaO E amino acid
LEHHPAIP_00087 4.5e-302 ybeC E amino acid
LEHHPAIP_00088 2e-80 S Aminoacyl-tRNA editing domain
LEHHPAIP_00089 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEHHPAIP_00090 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEHHPAIP_00092 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEHHPAIP_00093 0.0 uup S ABC transporter, ATP-binding protein
LEHHPAIP_00094 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEHHPAIP_00095 5.9e-227 mtnE 2.6.1.83 E Aminotransferase
LEHHPAIP_00096 1.6e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
LEHHPAIP_00097 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEHHPAIP_00098 7.6e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEHHPAIP_00099 2e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEHHPAIP_00100 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEHHPAIP_00101 2e-100 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
LEHHPAIP_00102 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
LEHHPAIP_00104 9.4e-27 L PFAM Integrase catalytic region
LEHHPAIP_00105 1.7e-67 L Belongs to the 'phage' integrase family
LEHHPAIP_00106 8.1e-149 3.2.1.18 GH33 M Rib/alpha-like repeat
LEHHPAIP_00107 5.3e-54 U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEHHPAIP_00108 3.5e-174 S Domain of unknown function (DUF389)
LEHHPAIP_00109 1e-88 L Recombinase
LEHHPAIP_00110 1.2e-68 K DNA binding
LEHHPAIP_00111 1e-120 L helicase activity
LEHHPAIP_00112 4.9e-207 L helicase activity
LEHHPAIP_00114 1.8e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEHHPAIP_00115 2e-163 L PFAM Integrase catalytic region
LEHHPAIP_00116 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LEHHPAIP_00117 7.9e-35 copZ C Heavy-metal-associated domain
LEHHPAIP_00118 1.2e-94 dps P Belongs to the Dps family
LEHHPAIP_00119 5.2e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
LEHHPAIP_00120 6.3e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
LEHHPAIP_00121 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
LEHHPAIP_00122 2e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
LEHHPAIP_00123 1.5e-69 L Recombinase
LEHHPAIP_00124 2.6e-67 L Recombinase
LEHHPAIP_00125 1.7e-21 L recombinase activity
LEHHPAIP_00126 4.7e-19 L Recombinase zinc beta ribbon domain
LEHHPAIP_00127 1.3e-68 L Recombinase zinc beta ribbon domain
LEHHPAIP_00128 8.2e-19
LEHHPAIP_00129 2.4e-29 S Bacteriophage holin family
LEHHPAIP_00130 7.2e-54 S Phage head-tail joining protein
LEHHPAIP_00131 1.3e-39 S Phage gp6-like head-tail connector protein
LEHHPAIP_00132 8.8e-172 S Phage capsid family
LEHHPAIP_00133 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEHHPAIP_00134 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
LEHHPAIP_00135 6.6e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEHHPAIP_00136 1.2e-102 pncA Q Isochorismatase family
LEHHPAIP_00137 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
LEHHPAIP_00138 1e-270 ywfO S HD domain protein
LEHHPAIP_00139 2.1e-146 yxeH S hydrolase
LEHHPAIP_00140 1.2e-47
LEHHPAIP_00141 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEHHPAIP_00142 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEHHPAIP_00143 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LEHHPAIP_00144 1.2e-117 znuB U ABC 3 transport family
LEHHPAIP_00145 2.2e-122 fhuC P ABC transporter
LEHHPAIP_00146 1.8e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
LEHHPAIP_00147 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEHHPAIP_00148 6.8e-37 veg S Biofilm formation stimulator VEG
LEHHPAIP_00149 3.6e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEHHPAIP_00150 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEHHPAIP_00151 3.5e-154 tatD L hydrolase, TatD family
LEHHPAIP_00152 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEHHPAIP_00153 1.2e-160 yunF F Protein of unknown function DUF72
LEHHPAIP_00155 3.4e-129 cobB K SIR2 family
LEHHPAIP_00156 1.6e-177
LEHHPAIP_00157 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LEHHPAIP_00158 2.1e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
LEHHPAIP_00159 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEHHPAIP_00160 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
LEHHPAIP_00161 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
LEHHPAIP_00162 0.0 helD 3.6.4.12 L DNA helicase
LEHHPAIP_00163 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEHHPAIP_00165 4.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEHHPAIP_00166 5.2e-265 yfnA E amino acid
LEHHPAIP_00167 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEHHPAIP_00168 8.9e-41 1.3.5.4 S FMN binding
LEHHPAIP_00169 7.1e-220 norA EGP Major facilitator Superfamily
LEHHPAIP_00170 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LEHHPAIP_00171 6.3e-154 metQ1 P Belongs to the nlpA lipoprotein family
LEHHPAIP_00172 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEHHPAIP_00173 3.1e-103 metI P ABC transporter permease
LEHHPAIP_00174 1.2e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LEHHPAIP_00175 6e-189 clcA P chloride
LEHHPAIP_00176 8.8e-215 L transposase, IS605 OrfB family
LEHHPAIP_00177 3.4e-58 L PFAM transposase IS200-family protein
LEHHPAIP_00178 7.4e-25 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LEHHPAIP_00179 7.1e-84 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEHHPAIP_00180 2.4e-211 yfnA E Amino Acid
LEHHPAIP_00181 2.6e-176 S FRG
LEHHPAIP_00182 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEHHPAIP_00183 6e-115 comFC S Competence protein
LEHHPAIP_00184 3.6e-249 comFA L Helicase C-terminal domain protein
LEHHPAIP_00185 2.1e-106 yvyE 3.4.13.9 S YigZ family
LEHHPAIP_00186 2.2e-44
LEHHPAIP_00187 3.1e-57 yhaI S Protein of unknown function (DUF805)
LEHHPAIP_00188 6.2e-140 IQ reductase
LEHHPAIP_00189 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
LEHHPAIP_00190 1e-280 hsdM 2.1.1.72 V type I restriction-modification system
LEHHPAIP_00191 1.6e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
LEHHPAIP_00192 8.9e-178 L Belongs to the 'phage' integrase family
LEHHPAIP_00193 9.1e-55 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
LEHHPAIP_00194 3.3e-161 L restriction endonuclease
LEHHPAIP_00195 2e-89 mrr L restriction endonuclease
LEHHPAIP_00196 0.0 L PLD-like domain
LEHHPAIP_00198 2e-09 IQ KR domain
LEHHPAIP_00199 6.2e-114 IQ KR domain
LEHHPAIP_00200 3.3e-133 S membrane transporter protein
LEHHPAIP_00201 7.9e-97 S ABC-type cobalt transport system, permease component
LEHHPAIP_00202 4.4e-250 cbiO1 S ABC transporter, ATP-binding protein
LEHHPAIP_00203 6.6e-111 P Cobalt transport protein
LEHHPAIP_00204 1.6e-52 yvlA
LEHHPAIP_00205 0.0 yjcE P Sodium proton antiporter
LEHHPAIP_00206 6.4e-52 ypaA S Protein of unknown function (DUF1304)
LEHHPAIP_00207 1.7e-187 D Alpha beta
LEHHPAIP_00208 1e-72 K Transcriptional regulator
LEHHPAIP_00209 3.2e-158
LEHHPAIP_00210 4.1e-87 1.6.5.5 C Zinc-binding dehydrogenase
LEHHPAIP_00211 4.4e-23 1.6.5.5 C Zinc-binding dehydrogenase
LEHHPAIP_00212 4.2e-256 G PTS system Galactitol-specific IIC component
LEHHPAIP_00213 1.7e-210 EGP Major facilitator Superfamily
LEHHPAIP_00214 3.9e-135 V ABC transporter
LEHHPAIP_00215 8.2e-115
LEHHPAIP_00216 8.8e-15
LEHHPAIP_00218 1.5e-169 whiA K May be required for sporulation
LEHHPAIP_00219 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LEHHPAIP_00220 1.2e-160 rapZ S Displays ATPase and GTPase activities
LEHHPAIP_00221 2.7e-244 steT E amino acid
LEHHPAIP_00222 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEHHPAIP_00223 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEHHPAIP_00224 2e-13
LEHHPAIP_00225 5.1e-116 yfbR S HD containing hydrolase-like enzyme
LEHHPAIP_00226 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LEHHPAIP_00227 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
LEHHPAIP_00228 1.9e-161 aatB ET PFAM extracellular solute-binding protein, family 3
LEHHPAIP_00229 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LEHHPAIP_00230 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEHHPAIP_00231 2.7e-168 lutA C Cysteine-rich domain
LEHHPAIP_00232 3.5e-293 lutB C 4Fe-4S dicluster domain
LEHHPAIP_00233 4.6e-137 yrjD S LUD domain
LEHHPAIP_00234 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEHHPAIP_00235 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LEHHPAIP_00236 2.1e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEHHPAIP_00237 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEHHPAIP_00238 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
LEHHPAIP_00239 7.7e-31 KT PspC domain protein
LEHHPAIP_00240 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEHHPAIP_00241 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEHHPAIP_00242 1.4e-153 EG EamA-like transporter family
LEHHPAIP_00243 2.1e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
LEHHPAIP_00244 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEHHPAIP_00245 3.6e-154 KT YcbB domain
LEHHPAIP_00246 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
LEHHPAIP_00248 1e-25
LEHHPAIP_00249 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
LEHHPAIP_00250 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
LEHHPAIP_00251 4.1e-153 glcU U sugar transport
LEHHPAIP_00252 5.8e-272 yclK 2.7.13.3 T Histidine kinase
LEHHPAIP_00253 1.6e-134 K response regulator
LEHHPAIP_00255 1.3e-76 lytE M Lysin motif
LEHHPAIP_00256 1.1e-147 XK27_02985 S Cof-like hydrolase
LEHHPAIP_00257 1.8e-78 K Transcriptional regulator
LEHHPAIP_00258 0.0 oatA I Acyltransferase
LEHHPAIP_00259 5.6e-52
LEHHPAIP_00260 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEHHPAIP_00261 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEHHPAIP_00262 1.7e-125 ybbR S YbbR-like protein
LEHHPAIP_00263 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEHHPAIP_00264 3.4e-247 fucP G Major Facilitator Superfamily
LEHHPAIP_00265 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LEHHPAIP_00266 1.1e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEHHPAIP_00267 3e-167 murB 1.3.1.98 M Cell wall formation
LEHHPAIP_00268 3.9e-101 dnaQ 2.7.7.7 L DNA polymerase III
LEHHPAIP_00269 2.2e-75 S PAS domain
LEHHPAIP_00270 4.4e-86 K Acetyltransferase (GNAT) domain
LEHHPAIP_00271 2.2e-79 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
LEHHPAIP_00272 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LEHHPAIP_00273 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEHHPAIP_00274 9.1e-104 yxjI
LEHHPAIP_00275 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LEHHPAIP_00276 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEHHPAIP_00277 3.2e-141 est 3.1.1.1 S Serine aminopeptidase, S33
LEHHPAIP_00278 1.8e-34 secG U Preprotein translocase
LEHHPAIP_00279 9e-292 clcA P chloride
LEHHPAIP_00280 1.2e-244 yifK E Amino acid permease
LEHHPAIP_00281 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEHHPAIP_00282 4.5e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEHHPAIP_00283 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LEHHPAIP_00284 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEHHPAIP_00286 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEHHPAIP_00287 9.4e-17
LEHHPAIP_00288 5.1e-159 K Transcriptional regulator
LEHHPAIP_00289 3.8e-85 lacA S transferase hexapeptide repeat
LEHHPAIP_00290 3.1e-133 S Hydrolases of the alpha beta superfamily
LEHHPAIP_00291 2.6e-12 S Alpha beta hydrolase
LEHHPAIP_00292 1.7e-89 S Alpha beta hydrolase
LEHHPAIP_00293 1.7e-153 tesE Q hydratase
LEHHPAIP_00294 6.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LEHHPAIP_00295 2.4e-228 aadAT EK Aminotransferase, class I
LEHHPAIP_00296 2.3e-155 ypuA S Protein of unknown function (DUF1002)
LEHHPAIP_00297 7.5e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
LEHHPAIP_00298 9.3e-145 K Transcriptional regulator
LEHHPAIP_00299 2.3e-159 akr5f 1.1.1.346 S reductase
LEHHPAIP_00300 7.5e-99 qorB 1.6.5.2 GM NmrA-like family
LEHHPAIP_00301 4.2e-59 yneR
LEHHPAIP_00302 7.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
LEHHPAIP_00303 1.6e-138 T EAL domain
LEHHPAIP_00304 2.2e-246 pgaC GT2 M Glycosyl transferase
LEHHPAIP_00305 3.7e-82
LEHHPAIP_00306 5e-171 2.7.7.65 T GGDEF domain
LEHHPAIP_00307 2.2e-120 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
LEHHPAIP_00308 1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
LEHHPAIP_00309 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
LEHHPAIP_00310 1e-17 folT S ECF transporter, substrate-specific component
LEHHPAIP_00311 6.1e-39 folT S ECF transporter, substrate-specific component
LEHHPAIP_00312 5.5e-48 K Transcriptional regulator
LEHHPAIP_00313 0.0 pepN 3.4.11.2 E aminopeptidase
LEHHPAIP_00314 1.8e-84 ylbE GM NAD dependent epimerase dehydratase family protein
LEHHPAIP_00315 1.3e-12 ylbE GM NAD dependent epimerase dehydratase family protein
LEHHPAIP_00316 8.8e-256 pepC 3.4.22.40 E aminopeptidase
LEHHPAIP_00317 2.2e-210 EGP Major facilitator Superfamily
LEHHPAIP_00318 6.8e-232
LEHHPAIP_00319 4e-83 K Transcriptional regulator, HxlR family
LEHHPAIP_00320 4.1e-107 XK27_02070 S Nitroreductase family
LEHHPAIP_00321 1.8e-50 hxlR K Transcriptional regulator, HxlR family
LEHHPAIP_00322 1.2e-120 GM NmrA-like family
LEHHPAIP_00323 1.6e-73 elaA S Gnat family
LEHHPAIP_00324 5.7e-36 S Cytochrome B5
LEHHPAIP_00325 1.3e-218 yxjG_1 E methionine synthase, vitamin-B12 independent
LEHHPAIP_00327 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEHHPAIP_00328 8.6e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEHHPAIP_00329 1.5e-237 E amino acid
LEHHPAIP_00330 2.8e-31 npp S type I phosphodiesterase nucleotide pyrophosphatase
LEHHPAIP_00331 1.7e-47 npp S type I phosphodiesterase nucleotide pyrophosphatase
LEHHPAIP_00332 1.1e-101 npp S type I phosphodiesterase nucleotide pyrophosphatase
LEHHPAIP_00333 4.2e-84 yxiO S Vacuole effluxer Atg22 like
LEHHPAIP_00334 1.2e-74 yxiO S Vacuole effluxer Atg22 like
LEHHPAIP_00337 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEHHPAIP_00338 1.5e-28
LEHHPAIP_00339 1.5e-147 S Hydrolases of the alpha beta superfamily
LEHHPAIP_00340 8e-196 adhP 1.1.1.1 C alcohol dehydrogenase
LEHHPAIP_00341 4.4e-77 ctsR K Belongs to the CtsR family
LEHHPAIP_00342 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEHHPAIP_00343 3e-110 K Bacterial regulatory proteins, tetR family
LEHHPAIP_00344 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEHHPAIP_00345 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEHHPAIP_00346 2.3e-199 ykiI
LEHHPAIP_00347 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
LEHHPAIP_00348 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEHHPAIP_00349 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEHHPAIP_00350 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEHHPAIP_00351 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LEHHPAIP_00352 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEHHPAIP_00353 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
LEHHPAIP_00354 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEHHPAIP_00355 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEHHPAIP_00356 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEHHPAIP_00357 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEHHPAIP_00358 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEHHPAIP_00359 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEHHPAIP_00360 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
LEHHPAIP_00361 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEHHPAIP_00362 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEHHPAIP_00363 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEHHPAIP_00364 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEHHPAIP_00365 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEHHPAIP_00366 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEHHPAIP_00367 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEHHPAIP_00368 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEHHPAIP_00369 2.9e-24 rpmD J Ribosomal protein L30
LEHHPAIP_00370 1.5e-63 rplO J Binds to the 23S rRNA
LEHHPAIP_00371 1.7e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEHHPAIP_00372 4.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEHHPAIP_00373 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEHHPAIP_00374 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LEHHPAIP_00375 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEHHPAIP_00376 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEHHPAIP_00377 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEHHPAIP_00378 1.1e-62 rplQ J Ribosomal protein L17
LEHHPAIP_00379 4.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEHHPAIP_00380 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEHHPAIP_00381 1.7e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEHHPAIP_00382 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEHHPAIP_00383 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEHHPAIP_00384 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LEHHPAIP_00385 8e-140 IQ reductase
LEHHPAIP_00386 1.5e-112 acmC 3.2.1.96 NU mannosyl-glycoprotein
LEHHPAIP_00387 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEHHPAIP_00388 2.1e-210 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEHHPAIP_00389 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LEHHPAIP_00390 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEHHPAIP_00391 1.2e-202 camS S sex pheromone
LEHHPAIP_00392 7e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEHHPAIP_00393 9.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEHHPAIP_00394 9.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEHHPAIP_00395 9.6e-186 yegS 2.7.1.107 G Lipid kinase
LEHHPAIP_00396 9.8e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEHHPAIP_00397 7.9e-14 L PFAM Integrase catalytic region
LEHHPAIP_00398 3.7e-56 ltrA S Bacterial low temperature requirement A protein (LtrA)
LEHHPAIP_00399 2.6e-43 ltrA S Bacterial low temperature requirement A protein (LtrA)
LEHHPAIP_00400 1.6e-79 uspA T universal stress protein
LEHHPAIP_00401 4e-78 K AsnC family
LEHHPAIP_00402 4.5e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEHHPAIP_00403 9.2e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
LEHHPAIP_00404 6.2e-10 K helix_turn_helix, mercury resistance
LEHHPAIP_00405 1.1e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEHHPAIP_00406 3.8e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
LEHHPAIP_00407 0.0 ysaB V FtsX-like permease family
LEHHPAIP_00408 2.9e-134 macB2 V ABC transporter, ATP-binding protein
LEHHPAIP_00409 5.3e-181 T PhoQ Sensor
LEHHPAIP_00410 5.4e-124 K response regulator
LEHHPAIP_00411 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
LEHHPAIP_00412 2.4e-133 pnuC H nicotinamide mononucleotide transporter
LEHHPAIP_00413 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEHHPAIP_00414 6.2e-202
LEHHPAIP_00415 3.5e-52
LEHHPAIP_00416 9.1e-36
LEHHPAIP_00417 3.1e-92 yxkA S Phosphatidylethanolamine-binding protein
LEHHPAIP_00418 1.2e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
LEHHPAIP_00419 2.5e-175 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
LEHHPAIP_00420 1.6e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEHHPAIP_00421 1.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LEHHPAIP_00422 5.4e-181 galR K Transcriptional regulator
LEHHPAIP_00424 3.7e-82 usp6 T universal stress protein
LEHHPAIP_00425 4.4e-46
LEHHPAIP_00426 1.8e-240 rarA L recombination factor protein RarA
LEHHPAIP_00427 1.8e-84 yueI S Protein of unknown function (DUF1694)
LEHHPAIP_00428 4.7e-21
LEHHPAIP_00429 4.3e-08 S Acyltransferase family
LEHHPAIP_00430 2.5e-64 XK27_01125 L PFAM IS66 Orf2 family protein
LEHHPAIP_00432 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LEHHPAIP_00433 5.5e-45 yitW S Pfam:DUF59
LEHHPAIP_00434 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LEHHPAIP_00438 3.5e-97 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LEHHPAIP_00439 8.6e-47 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
LEHHPAIP_00440 5.6e-48 XK27_01125 L PFAM IS66 Orf2 family protein
LEHHPAIP_00441 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEHHPAIP_00442 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LEHHPAIP_00443 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEHHPAIP_00444 1.9e-172 dnaI L Primosomal protein DnaI
LEHHPAIP_00445 1.9e-221 dnaB L replication initiation and membrane attachment
LEHHPAIP_00446 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEHHPAIP_00447 5e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEHHPAIP_00448 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEHHPAIP_00449 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEHHPAIP_00450 1e-15 yoaK S Protein of unknown function (DUF1275)
LEHHPAIP_00451 2.4e-72 yoaK S Protein of unknown function (DUF1275)
LEHHPAIP_00452 1.4e-119 ybhL S Belongs to the BI1 family
LEHHPAIP_00453 1.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LEHHPAIP_00454 9.4e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEHHPAIP_00455 1.8e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LEHHPAIP_00456 1.1e-56 ytzB S Small secreted protein
LEHHPAIP_00457 2.6e-11 glsA 3.5.1.2 E Belongs to the glutaminase family
LEHHPAIP_00458 1.3e-64 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
LEHHPAIP_00459 1.3e-12 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
LEHHPAIP_00460 9.5e-16 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
LEHHPAIP_00461 2.5e-16 S YSIRK type signal peptide
LEHHPAIP_00462 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEHHPAIP_00463 3.9e-218 ecsB U ABC transporter
LEHHPAIP_00464 6.7e-136 ecsA V ABC transporter, ATP-binding protein
LEHHPAIP_00465 1.2e-76 hit FG histidine triad
LEHHPAIP_00467 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEHHPAIP_00468 0.0 L AAA domain
LEHHPAIP_00469 2.8e-221 yhaO L Ser Thr phosphatase family protein
LEHHPAIP_00470 9.4e-38 yheA S Belongs to the UPF0342 family
LEHHPAIP_00471 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEHHPAIP_00472 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LEHHPAIP_00473 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEHHPAIP_00474 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEHHPAIP_00476 1.3e-36
LEHHPAIP_00477 5.1e-43
LEHHPAIP_00478 2.1e-208 folP 2.5.1.15 H dihydropteroate synthase
LEHHPAIP_00479 1.3e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
LEHHPAIP_00480 4.7e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LEHHPAIP_00481 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
LEHHPAIP_00482 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
LEHHPAIP_00483 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LEHHPAIP_00484 8.4e-69
LEHHPAIP_00486 2.5e-43
LEHHPAIP_00487 2.7e-109 S CAAX protease self-immunity
LEHHPAIP_00488 3.1e-31
LEHHPAIP_00489 6.8e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEHHPAIP_00490 7.4e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
LEHHPAIP_00491 2.2e-113
LEHHPAIP_00492 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
LEHHPAIP_00493 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEHHPAIP_00494 7.3e-86 uspA T Belongs to the universal stress protein A family
LEHHPAIP_00495 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
LEHHPAIP_00496 5.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEHHPAIP_00497 1.1e-300 ytgP S Polysaccharide biosynthesis protein
LEHHPAIP_00498 7.6e-42
LEHHPAIP_00499 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEHHPAIP_00500 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEHHPAIP_00501 5.1e-93 tag 3.2.2.20 L glycosylase
LEHHPAIP_00502 4.6e-258 EGP Major facilitator Superfamily
LEHHPAIP_00503 2.8e-84 perR P Belongs to the Fur family
LEHHPAIP_00504 8.2e-233 cycA E Amino acid permease
LEHHPAIP_00505 4.5e-100 V VanZ like family
LEHHPAIP_00506 1e-23
LEHHPAIP_00507 5.5e-33 S Uncharacterised protein family (UPF0236)
LEHHPAIP_00508 3.9e-237 L Transposase
LEHHPAIP_00509 3.7e-85 C Flavodoxin
LEHHPAIP_00510 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
LEHHPAIP_00511 3.8e-182 1.1.1.1 C nadph quinone reductase
LEHHPAIP_00512 1.3e-98 M Protein of unknown function (DUF3737)
LEHHPAIP_00513 1.1e-225 4.4.1.8 E Aminotransferase, class I
LEHHPAIP_00514 3.1e-92 S Peptidase propeptide and YPEB domain
LEHHPAIP_00515 4e-224 T GHKL domain
LEHHPAIP_00516 9.9e-118 T Transcriptional regulatory protein, C terminal
LEHHPAIP_00517 3.5e-158 mleP3 S Membrane transport protein
LEHHPAIP_00518 3.9e-237 L Transposase
LEHHPAIP_00519 2.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEHHPAIP_00520 7.6e-195 EGP Major facilitator Superfamily
LEHHPAIP_00521 4.3e-86 ymdB S Macro domain protein
LEHHPAIP_00522 4.4e-98 K Helix-turn-helix XRE-family like proteins
LEHHPAIP_00523 0.0 pepO 3.4.24.71 O Peptidase family M13
LEHHPAIP_00524 1.4e-47
LEHHPAIP_00525 4.5e-236 S Putative metallopeptidase domain
LEHHPAIP_00526 3.4e-203 3.1.3.1 S associated with various cellular activities
LEHHPAIP_00527 3.4e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LEHHPAIP_00528 5.9e-64 yeaO S Protein of unknown function, DUF488
LEHHPAIP_00530 3.4e-118 yrkL S Flavodoxin-like fold
LEHHPAIP_00531 5.2e-53
LEHHPAIP_00532 1.8e-16 S Domain of unknown function (DUF4767)
LEHHPAIP_00533 1.2e-135 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEHHPAIP_00534 1.7e-47
LEHHPAIP_00535 8.9e-206 nrnB S DHHA1 domain
LEHHPAIP_00536 1.8e-226 S Uncharacterized protein conserved in bacteria (DUF2325)
LEHHPAIP_00537 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
LEHHPAIP_00538 1.7e-105 NU mannosyl-glycoprotein
LEHHPAIP_00539 7.8e-143 S Putative ABC-transporter type IV
LEHHPAIP_00540 1.9e-273 S ABC transporter, ATP-binding protein
LEHHPAIP_00541 2.6e-17 relB L RelB antitoxin
LEHHPAIP_00542 6.4e-18 K Helix-turn-helix domain
LEHHPAIP_00543 4.5e-44 arsB 1.20.4.1 P Sodium Bile acid symporter family
LEHHPAIP_00544 2.7e-62 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEHHPAIP_00545 1.8e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
LEHHPAIP_00546 1.6e-180 arsB 1.20.4.1 P Sodium Bile acid symporter family
LEHHPAIP_00547 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEHHPAIP_00548 9.4e-56 cadX K Bacterial regulatory protein, arsR family
LEHHPAIP_00549 2.8e-95 cadD P Cadmium resistance transporter
LEHHPAIP_00550 1.1e-13 K Transcriptional
LEHHPAIP_00551 3.9e-24 L Integrase
LEHHPAIP_00552 1e-28 WQ51_00220 K Helix-turn-helix domain
LEHHPAIP_00553 7.4e-104 S Protein of unknown function (DUF3278)
LEHHPAIP_00555 1.7e-73 M PFAM NLP P60 protein
LEHHPAIP_00556 4.1e-181 ABC-SBP S ABC transporter
LEHHPAIP_00557 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
LEHHPAIP_00558 1.8e-136 XK27_08845 S ABC transporter, ATP-binding protein
LEHHPAIP_00559 5.1e-96 P Cadmium resistance transporter
LEHHPAIP_00560 9.9e-55 K Transcriptional regulator, ArsR family
LEHHPAIP_00561 9.5e-234 mepA V MATE efflux family protein
LEHHPAIP_00562 3.2e-55 trxA O Belongs to the thioredoxin family
LEHHPAIP_00563 6.6e-131 terC P membrane
LEHHPAIP_00564 1.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEHHPAIP_00565 2.8e-168 corA P CorA-like Mg2+ transporter protein
LEHHPAIP_00566 1.2e-279 pipD E Dipeptidase
LEHHPAIP_00567 4.7e-241 pbuX F xanthine permease
LEHHPAIP_00568 2.1e-247 nhaC C Na H antiporter NhaC
LEHHPAIP_00569 3.6e-269 S C4-dicarboxylate anaerobic carrier
LEHHPAIP_00570 2.9e-70 IQ Enoyl-(Acyl carrier protein) reductase
LEHHPAIP_00571 4.6e-36 K Bacterial transcriptional regulator
LEHHPAIP_00572 2.7e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
LEHHPAIP_00573 1.2e-39
LEHHPAIP_00574 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEHHPAIP_00575 1.1e-206 gldA 1.1.1.6 C dehydrogenase
LEHHPAIP_00576 1.8e-113 L transposase IS116 IS110 IS902 family protein
LEHHPAIP_00577 4.5e-82 L transposase IS116 IS110 IS902 family protein
LEHHPAIP_00578 2.2e-38 S Alpha beta hydrolase
LEHHPAIP_00579 1.5e-63 S Alpha beta hydrolase
LEHHPAIP_00580 5.3e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEHHPAIP_00581 4.8e-97
LEHHPAIP_00583 1.3e-122 yciB M ErfK YbiS YcfS YnhG
LEHHPAIP_00584 1.4e-259 S Putative peptidoglycan binding domain
LEHHPAIP_00585 1.5e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
LEHHPAIP_00586 3.6e-85
LEHHPAIP_00587 1.5e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
LEHHPAIP_00588 4.9e-213 yttB EGP Major facilitator Superfamily
LEHHPAIP_00589 1e-100
LEHHPAIP_00590 1e-24
LEHHPAIP_00591 6.7e-173 scrR K Transcriptional regulator, LacI family
LEHHPAIP_00592 1.1e-192 V Beta-lactamase
LEHHPAIP_00593 6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LEHHPAIP_00594 1.8e-98 yhiD S MgtC family
LEHHPAIP_00595 7e-54 S GyrI-like small molecule binding domain
LEHHPAIP_00596 3e-125 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
LEHHPAIP_00597 3.8e-183 ybhR V ABC transporter
LEHHPAIP_00598 1.2e-90 K Bacterial regulatory proteins, tetR family
LEHHPAIP_00599 7.3e-110 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
LEHHPAIP_00600 3.2e-50 azlD E Branched-chain amino acid transport
LEHHPAIP_00601 5.3e-119 azlC E azaleucine resistance protein AzlC
LEHHPAIP_00602 6.9e-259 K Aminotransferase class I and II
LEHHPAIP_00603 3.2e-92 S amidohydrolase
LEHHPAIP_00604 2.8e-79 S amidohydrolase
LEHHPAIP_00605 5.5e-105 L hmm pf00665
LEHHPAIP_00606 2.1e-37 L PFAM Integrase catalytic region
LEHHPAIP_00607 3.3e-121 L PFAM Integrase catalytic region
LEHHPAIP_00608 9.2e-49 2.3.1.183 M Acetyltransferase GNAT family
LEHHPAIP_00609 2.5e-14 2.3.1.183 M Acetyltransferase GNAT family
LEHHPAIP_00610 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LEHHPAIP_00611 1.4e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
LEHHPAIP_00612 1.7e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEHHPAIP_00613 0.0 asnB 6.3.5.4 E Asparagine synthase
LEHHPAIP_00614 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEHHPAIP_00615 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEHHPAIP_00616 1.1e-130 jag S R3H domain protein
LEHHPAIP_00617 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEHHPAIP_00618 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEHHPAIP_00619 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LEHHPAIP_00620 1.1e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEHHPAIP_00621 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEHHPAIP_00622 4.9e-34 yaaA S S4 domain protein YaaA
LEHHPAIP_00623 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEHHPAIP_00624 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEHHPAIP_00625 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEHHPAIP_00626 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
LEHHPAIP_00627 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEHHPAIP_00628 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEHHPAIP_00629 1.3e-75 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEHHPAIP_00630 6.5e-18 deoR K sugar-binding domain protein
LEHHPAIP_00631 1.1e-52 deoR K sugar-binding domain protein
LEHHPAIP_00632 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LEHHPAIP_00633 2e-74 rplI J Binds to the 23S rRNA
LEHHPAIP_00634 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LEHHPAIP_00635 2.6e-206 yttB EGP Major facilitator Superfamily
LEHHPAIP_00636 9.1e-61
LEHHPAIP_00637 1.4e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
LEHHPAIP_00638 3.8e-38 Z012_01130 S Fic/DOC family
LEHHPAIP_00639 3e-71 Z012_01130 S Fic/DOC family
LEHHPAIP_00641 1.8e-72 K helix_turn_helix multiple antibiotic resistance protein
LEHHPAIP_00642 2.9e-307 lmrA 3.6.3.44 V ABC transporter
LEHHPAIP_00644 3.1e-130 K response regulator
LEHHPAIP_00645 0.0 vicK 2.7.13.3 T Histidine kinase
LEHHPAIP_00646 2e-244 yycH S YycH protein
LEHHPAIP_00647 7.8e-149 yycI S YycH protein
LEHHPAIP_00648 5.9e-154 vicX 3.1.26.11 S domain protein
LEHHPAIP_00649 6.6e-216 htrA 3.4.21.107 O serine protease
LEHHPAIP_00650 1e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
LEHHPAIP_00651 1.5e-175 ABC-SBP S ABC transporter
LEHHPAIP_00652 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEHHPAIP_00654 2.9e-96 S reductase
LEHHPAIP_00655 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
LEHHPAIP_00656 1.3e-154 glcU U sugar transport
LEHHPAIP_00657 1.9e-149 E Glyoxalase-like domain
LEHHPAIP_00658 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEHHPAIP_00659 4.4e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
LEHHPAIP_00660 2.8e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEHHPAIP_00661 2.8e-128 V ABC transporter
LEHHPAIP_00662 7.8e-214 bacI V MacB-like periplasmic core domain
LEHHPAIP_00663 3.8e-22
LEHHPAIP_00664 4.8e-260 S Putative peptidoglycan binding domain
LEHHPAIP_00666 1.6e-08 2.7.13.3 T GHKL domain
LEHHPAIP_00667 8.7e-54 L An automated process has identified a potential problem with this gene model
LEHHPAIP_00668 3.6e-85 K FR47-like protein
LEHHPAIP_00669 4e-119 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
LEHHPAIP_00672 5e-75 osmC O OsmC-like protein
LEHHPAIP_00673 8.3e-174 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEHHPAIP_00674 1.8e-215 patA 2.6.1.1 E Aminotransferase
LEHHPAIP_00675 7.8e-32
LEHHPAIP_00676 0.0 clpL O associated with various cellular activities
LEHHPAIP_00678 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
LEHHPAIP_00679 5.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEHHPAIP_00680 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LEHHPAIP_00681 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LEHHPAIP_00682 4.3e-172 malR K Transcriptional regulator, LacI family
LEHHPAIP_00683 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
LEHHPAIP_00684 1.1e-256 malT G Major Facilitator
LEHHPAIP_00685 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
LEHHPAIP_00686 1.6e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
LEHHPAIP_00687 1e-71
LEHHPAIP_00688 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
LEHHPAIP_00689 3.3e-118 K response regulator
LEHHPAIP_00690 3.1e-226 sptS 2.7.13.3 T Histidine kinase
LEHHPAIP_00691 4.7e-216 yfeO P Voltage gated chloride channel
LEHHPAIP_00692 5.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
LEHHPAIP_00693 8.6e-136 puuD S peptidase C26
LEHHPAIP_00694 5.9e-168 yvgN C Aldo keto reductase
LEHHPAIP_00695 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
LEHHPAIP_00696 1.5e-86 hmpT S ECF-type riboflavin transporter, S component
LEHHPAIP_00697 2e-263 nox C NADH oxidase
LEHHPAIP_00698 3.8e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEHHPAIP_00699 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEHHPAIP_00700 3.9e-78
LEHHPAIP_00701 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEHHPAIP_00703 9.3e-13 steT_1 E amino acid
LEHHPAIP_00704 4.3e-13 K Transcriptional regulator, TetR family
LEHHPAIP_00705 1e-73 K Transcriptional regulator, TetR family
LEHHPAIP_00706 8.3e-72
LEHHPAIP_00707 3.1e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
LEHHPAIP_00708 1.4e-270 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
LEHHPAIP_00709 3e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
LEHHPAIP_00710 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
LEHHPAIP_00711 7.5e-266 G Major Facilitator
LEHHPAIP_00712 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LEHHPAIP_00713 1.1e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEHHPAIP_00714 6.1e-260 G Major Facilitator
LEHHPAIP_00715 8.9e-176 K Transcriptional regulator, LacI family
LEHHPAIP_00716 7.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEHHPAIP_00717 5.4e-101 nqr 1.5.1.36 S reductase
LEHHPAIP_00718 1.2e-198 XK27_09615 S reductase
LEHHPAIP_00719 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEHHPAIP_00720 1.6e-54 S Short repeat of unknown function (DUF308)
LEHHPAIP_00721 2.5e-77 S Psort location Cytoplasmic, score
LEHHPAIP_00722 4.6e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
LEHHPAIP_00723 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
LEHHPAIP_00724 4.5e-152 yeaE S Aldo keto
LEHHPAIP_00725 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
LEHHPAIP_00726 4.7e-235 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
LEHHPAIP_00727 1.5e-146 xth 3.1.11.2 L exodeoxyribonuclease III
LEHHPAIP_00728 1.3e-88 lytE M LysM domain protein
LEHHPAIP_00729 0.0 oppD EP Psort location Cytoplasmic, score
LEHHPAIP_00730 2e-42 lytE M LysM domain protein
LEHHPAIP_00731 9.8e-158 sufD O Uncharacterized protein family (UPF0051)
LEHHPAIP_00732 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEHHPAIP_00733 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LEHHPAIP_00734 1.1e-57 lmrB EGP Major facilitator Superfamily
LEHHPAIP_00735 2.2e-152 lmrB EGP Major facilitator Superfamily
LEHHPAIP_00736 4.1e-98 2.3.1.128 K Acetyltransferase (GNAT) domain
LEHHPAIP_00737 6.8e-154 M Glycosyl hydrolases family 25
LEHHPAIP_00738 5.2e-57 S Bacteriophage holin of superfamily 6 (Holin_LLH)
LEHHPAIP_00739 8.4e-34
LEHHPAIP_00740 4.3e-131 E GDSL-like Lipase/Acylhydrolase
LEHHPAIP_00742 0.0 M Prophage endopeptidase tail
LEHHPAIP_00743 8.9e-147 S phage tail
LEHHPAIP_00744 2.6e-259 sca1 D Phage tail tape measure protein
LEHHPAIP_00745 1e-60
LEHHPAIP_00746 2.6e-55 S Phage tail assembly chaperone protein, TAC
LEHHPAIP_00747 7.7e-103 S Phage tail tube protein
LEHHPAIP_00748 8.4e-21 S Protein of unknown function (DUF3168)
LEHHPAIP_00749 4.2e-68 S Bacteriophage HK97-gp10, putative tail-component
LEHHPAIP_00750 7.9e-46
LEHHPAIP_00751 2.1e-64 S Phage gp6-like head-tail connector protein
LEHHPAIP_00752 1.1e-153
LEHHPAIP_00753 2.6e-101 S Domain of unknown function (DUF4355)
LEHHPAIP_00755 2e-173 S Phage Mu protein F like protein
LEHHPAIP_00756 3.3e-272 S Phage portal protein
LEHHPAIP_00757 1.1e-244 S Phage terminase, large subunit
LEHHPAIP_00759 1.6e-60 L Terminase small subunit
LEHHPAIP_00761 4.7e-79 arpU S Phage transcriptional regulator, ArpU family
LEHHPAIP_00768 8e-60 S VRR_NUC
LEHHPAIP_00770 2.6e-233 S Virulence-associated protein E
LEHHPAIP_00771 1.9e-136 S Bifunctional DNA primase/polymerase, N-terminal
LEHHPAIP_00772 1.7e-93
LEHHPAIP_00773 7.1e-141 L AAA domain
LEHHPAIP_00774 4e-259 res L Helicase C-terminal domain protein
LEHHPAIP_00775 2.7e-77 S Siphovirus Gp157
LEHHPAIP_00776 1.2e-29
LEHHPAIP_00778 8.8e-40
LEHHPAIP_00780 6e-15 XK27_10050 K Peptidase S24-like
LEHHPAIP_00781 2.4e-19 E Zn peptidase
LEHHPAIP_00782 9.7e-69
LEHHPAIP_00783 2.7e-26 S Domain of unknown function (DUF4352)
LEHHPAIP_00784 8.6e-143 L Belongs to the 'phage' integrase family
LEHHPAIP_00794 6.3e-238 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEHHPAIP_00795 3.5e-49 czrA K Transcriptional regulator, ArsR family
LEHHPAIP_00796 2.5e-36
LEHHPAIP_00797 0.0 yhcA V ABC transporter, ATP-binding protein
LEHHPAIP_00798 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
LEHHPAIP_00799 2.1e-167 hrtB V ABC transporter permease
LEHHPAIP_00800 1.8e-84 ygfC K transcriptional regulator (TetR family)
LEHHPAIP_00801 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
LEHHPAIP_00802 1.2e-286 mntH P H( )-stimulated, divalent metal cation uptake system
LEHHPAIP_00803 3.9e-237 L Transposase
LEHHPAIP_00804 6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LEHHPAIP_00805 8.3e-21
LEHHPAIP_00806 6e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
LEHHPAIP_00807 1.4e-167 L transposase, IS605 OrfB family
LEHHPAIP_00808 1e-295 L PFAM plasmid pRiA4b ORF-3 family protein
LEHHPAIP_00809 3.3e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
LEHHPAIP_00810 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEHHPAIP_00811 4.3e-158 mleR K LysR family
LEHHPAIP_00812 1.2e-302 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
LEHHPAIP_00813 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEHHPAIP_00814 5.8e-266 frdC 1.3.5.4 C FAD binding domain
LEHHPAIP_00815 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
LEHHPAIP_00816 3.9e-237 L Transposase
LEHHPAIP_00817 0.0 lacS G Transporter
LEHHPAIP_00818 2.3e-28
LEHHPAIP_00819 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEHHPAIP_00820 3.2e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEHHPAIP_00821 4.4e-190 yeaN P Transporter, major facilitator family protein
LEHHPAIP_00822 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
LEHHPAIP_00823 2.7e-82 nrdI F Belongs to the NrdI family
LEHHPAIP_00824 3.5e-236 yhdP S Transporter associated domain
LEHHPAIP_00825 1.4e-153 ypdB V (ABC) transporter
LEHHPAIP_00826 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
LEHHPAIP_00827 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
LEHHPAIP_00828 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
LEHHPAIP_00829 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
LEHHPAIP_00830 2.6e-160 S AI-2E family transporter
LEHHPAIP_00831 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
LEHHPAIP_00832 2.2e-160
LEHHPAIP_00833 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LEHHPAIP_00834 3.6e-138 eutJ E Hsp70 protein
LEHHPAIP_00835 8.3e-159 K helix_turn_helix, arabinose operon control protein
LEHHPAIP_00836 1.6e-37 pduA_4 CQ BMC
LEHHPAIP_00837 2.7e-134 pduB E BMC
LEHHPAIP_00838 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
LEHHPAIP_00839 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
LEHHPAIP_00840 6.2e-72 pduE 4.2.1.28 Q Dehydratase small subunit
LEHHPAIP_00841 5.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
LEHHPAIP_00842 4.5e-45 pduH S Dehydratase medium subunit
LEHHPAIP_00843 3.6e-57 pduK CQ BMC
LEHHPAIP_00844 7.8e-40 pduA_4 CQ BMC
LEHHPAIP_00845 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
LEHHPAIP_00846 1.3e-79 S Putative propanediol utilisation
LEHHPAIP_00847 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
LEHHPAIP_00848 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
LEHHPAIP_00849 4.5e-77 pduO S Haem-degrading
LEHHPAIP_00850 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
LEHHPAIP_00851 4.3e-203 pduQ C Iron-containing alcohol dehydrogenase
LEHHPAIP_00852 3.8e-218 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEHHPAIP_00853 3e-54 pduU E BMC
LEHHPAIP_00854 4.4e-117 3.1.3.48 T Pfam:Y_phosphatase3C
LEHHPAIP_00855 3.3e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
LEHHPAIP_00856 5.9e-68 P Cadmium resistance transporter
LEHHPAIP_00857 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
LEHHPAIP_00858 2.9e-73 fld C Flavodoxin
LEHHPAIP_00859 7.9e-117 XK27_04590 S NADPH-dependent FMN reductase
LEHHPAIP_00860 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
LEHHPAIP_00861 1.8e-169 cobD 4.1.1.81 E Aminotransferase class I and II
LEHHPAIP_00862 8.1e-204 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
LEHHPAIP_00863 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LEHHPAIP_00864 2.5e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
LEHHPAIP_00865 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
LEHHPAIP_00866 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
LEHHPAIP_00867 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
LEHHPAIP_00868 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
LEHHPAIP_00869 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
LEHHPAIP_00870 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
LEHHPAIP_00871 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
LEHHPAIP_00872 2.7e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
LEHHPAIP_00873 1.1e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
LEHHPAIP_00874 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
LEHHPAIP_00875 8.5e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
LEHHPAIP_00876 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
LEHHPAIP_00877 6.8e-103 cbiQ P Cobalt transport protein
LEHHPAIP_00878 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
LEHHPAIP_00879 6.6e-239 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
LEHHPAIP_00880 2.7e-58 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
LEHHPAIP_00881 5.4e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LEHHPAIP_00882 9.8e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LEHHPAIP_00883 6.2e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
LEHHPAIP_00884 4.3e-239 hemL 5.4.3.8 H Aminotransferase class-III
LEHHPAIP_00885 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
LEHHPAIP_00886 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LEHHPAIP_00887 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
LEHHPAIP_00888 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LEHHPAIP_00889 1.6e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
LEHHPAIP_00890 1.8e-55 cnrT EG PFAM EamA-like transporter family
LEHHPAIP_00891 1.7e-50 S Domain of unknown function (DUF4430)
LEHHPAIP_00892 1.1e-71 S ECF transporter, substrate-specific component
LEHHPAIP_00893 2.9e-19 S PFAM Archaeal ATPase
LEHHPAIP_00894 5.5e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEHHPAIP_00895 1.3e-17 K Winged helix DNA-binding domain
LEHHPAIP_00896 1.8e-288 lmrA V ABC transporter, ATP-binding protein
LEHHPAIP_00897 0.0 yfiC V ABC transporter
LEHHPAIP_00898 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
LEHHPAIP_00899 2.6e-269 pipD E Dipeptidase
LEHHPAIP_00900 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEHHPAIP_00901 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
LEHHPAIP_00902 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
LEHHPAIP_00903 2.4e-17 yagE E amino acid
LEHHPAIP_00904 2.1e-116 yagE E amino acid
LEHHPAIP_00905 4.6e-80 yagE E amino acid
LEHHPAIP_00906 4.2e-138 aroD S Serine hydrolase (FSH1)
LEHHPAIP_00907 9.1e-240 brnQ U Component of the transport system for branched-chain amino acids
LEHHPAIP_00908 8.4e-165 GK ROK family
LEHHPAIP_00909 0.0 tetP J elongation factor G
LEHHPAIP_00910 2.5e-80 uspA T universal stress protein
LEHHPAIP_00911 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
LEHHPAIP_00912 7.1e-63
LEHHPAIP_00913 8.9e-14
LEHHPAIP_00914 3.9e-237 L Transposase
LEHHPAIP_00915 2.8e-188 L Transposase IS66 family
LEHHPAIP_00916 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
LEHHPAIP_00917 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LEHHPAIP_00918 1.4e-47 gcvH E glycine cleavage
LEHHPAIP_00919 1.1e-220 rodA D Belongs to the SEDS family
LEHHPAIP_00920 1e-31 S Protein of unknown function (DUF2969)
LEHHPAIP_00921 1.9e-178 mbl D Cell shape determining protein MreB Mrl
LEHHPAIP_00922 3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEHHPAIP_00923 1.3e-33 ywzB S Protein of unknown function (DUF1146)
LEHHPAIP_00924 3.8e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LEHHPAIP_00925 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEHHPAIP_00926 4.8e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEHHPAIP_00927 4.4e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEHHPAIP_00928 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEHHPAIP_00929 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEHHPAIP_00930 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEHHPAIP_00931 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
LEHHPAIP_00932 7.7e-233 pyrP F Permease
LEHHPAIP_00933 4.4e-130 yibF S overlaps another CDS with the same product name
LEHHPAIP_00934 2.9e-191 yibE S overlaps another CDS with the same product name
LEHHPAIP_00935 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEHHPAIP_00936 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEHHPAIP_00937 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEHHPAIP_00938 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEHHPAIP_00939 1.5e-166 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEHHPAIP_00940 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEHHPAIP_00941 1.7e-107 tdk 2.7.1.21 F thymidine kinase
LEHHPAIP_00942 2.2e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
LEHHPAIP_00943 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
LEHHPAIP_00944 3e-10
LEHHPAIP_00945 6.1e-223 arcD U Amino acid permease
LEHHPAIP_00946 1.1e-259 E Arginine ornithine antiporter
LEHHPAIP_00947 2.7e-79 argR K Regulates arginine biosynthesis genes
LEHHPAIP_00948 2e-217 arcA 3.5.3.6 E Arginine
LEHHPAIP_00949 1.5e-183 ampC V Beta-lactamase
LEHHPAIP_00950 7e-19
LEHHPAIP_00951 0.0 M domain protein
LEHHPAIP_00952 9.7e-139 M domain protein
LEHHPAIP_00953 3.8e-90
LEHHPAIP_00954 7e-134 L Belongs to the 'phage' integrase family
LEHHPAIP_00955 2e-08 xre K sequence-specific DNA binding
LEHHPAIP_00956 2.6e-12
LEHHPAIP_00957 1.5e-29
LEHHPAIP_00958 1.8e-39 K COG3617 Prophage antirepressor
LEHHPAIP_00960 5e-08
LEHHPAIP_00964 8.9e-09 L DnaD domain protein
LEHHPAIP_00966 5.5e-68
LEHHPAIP_00969 4.6e-53
LEHHPAIP_00972 1.4e-47 yjcE P Sodium proton antiporter
LEHHPAIP_00973 5.9e-117 yjcE P Sodium proton antiporter
LEHHPAIP_00974 3.9e-40 yjcE P Sodium proton antiporter
LEHHPAIP_00975 2.3e-56
LEHHPAIP_00977 1.2e-85
LEHHPAIP_00978 0.0 copA 3.6.3.54 P P-type ATPase
LEHHPAIP_00979 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LEHHPAIP_00980 1.4e-101 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
LEHHPAIP_00982 1e-11 S by MetaGeneAnnotator
LEHHPAIP_00986 5.2e-41 S Domain of unknown function (DUF2479)
LEHHPAIP_00989 6e-218 M CHAP domain
LEHHPAIP_00990 1.9e-81 S Phage tail protein
LEHHPAIP_00991 5.2e-131 Z012_10445 D Phage tail tape measure protein
LEHHPAIP_00992 8.2e-14
LEHHPAIP_00994 1e-11 S by MetaGeneAnnotator
LEHHPAIP_00998 5.2e-41 S Domain of unknown function (DUF2479)
LEHHPAIP_01001 1.5e-224 M CHAP domain
LEHHPAIP_01002 1.4e-90 S Phage tail protein
LEHHPAIP_01003 1.8e-134 Z012_10445 D Phage tail tape measure protein
LEHHPAIP_01004 1.1e-13
LEHHPAIP_01005 9.9e-21 M CHAP domain
LEHHPAIP_01008 5.2e-41 S Domain of unknown function (DUF2479)
LEHHPAIP_01012 1e-11 S by MetaGeneAnnotator
LEHHPAIP_01014 1.3e-31
LEHHPAIP_01015 2.2e-24 S Bacteriophage holin of superfamily 6 (Holin_LLH)
LEHHPAIP_01016 1.7e-183 ps461 3.5.1.104 M hydrolase, family 25
LEHHPAIP_01017 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEHHPAIP_01018 1.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
LEHHPAIP_01019 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEHHPAIP_01020 3.4e-172
LEHHPAIP_01021 1.8e-43
LEHHPAIP_01022 2.9e-20
LEHHPAIP_01023 0.0 S SEC-C Motif Domain Protein
LEHHPAIP_01024 2e-49
LEHHPAIP_01025 8.6e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LEHHPAIP_01026 1.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEHHPAIP_01027 1.5e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LEHHPAIP_01028 1.3e-227 clcA_2 P Chloride transporter, ClC family
LEHHPAIP_01029 4.4e-129 L PFAM transposase IS116 IS110 IS902
LEHHPAIP_01030 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
LEHHPAIP_01031 9.3e-110 lssY 3.6.1.27 I Acid phosphatase homologues
LEHHPAIP_01032 2.3e-41 L Transposase IS66 family
LEHHPAIP_01033 6.4e-90 L Transposase IS66 family
LEHHPAIP_01034 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LEHHPAIP_01035 1.9e-102 proW P ABC transporter, permease protein
LEHHPAIP_01036 6.5e-142 proV E ABC transporter, ATP-binding protein
LEHHPAIP_01037 3.1e-105 proWZ P ABC transporter permease
LEHHPAIP_01038 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
LEHHPAIP_01039 3.8e-73 K Transcriptional regulator
LEHHPAIP_01040 1.6e-35 1.6.5.2 GM NAD(P)H-binding
LEHHPAIP_01042 3.7e-221 5.4.2.7 G Metalloenzyme superfamily
LEHHPAIP_01043 7.5e-311 cadA P P-type ATPase
LEHHPAIP_01044 1.3e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
LEHHPAIP_01045 2.3e-125
LEHHPAIP_01046 2.6e-52 S Sugar efflux transporter for intercellular exchange
LEHHPAIP_01047 6.1e-244 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
LEHHPAIP_01049 0.0 L Helicase C-terminal domain protein
LEHHPAIP_01050 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
LEHHPAIP_01051 4.1e-178 S Aldo keto reductase
LEHHPAIP_01053 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEHHPAIP_01054 1.9e-26 psiE S Phosphate-starvation-inducible E
LEHHPAIP_01055 5.9e-97 ydeN S Serine hydrolase
LEHHPAIP_01057 2.2e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEHHPAIP_01058 1.2e-253 nhaC C Na H antiporter NhaC
LEHHPAIP_01059 2.5e-36 S Cytochrome b5-like Heme/Steroid binding domain
LEHHPAIP_01060 1.8e-113 ywnB S NAD(P)H-binding
LEHHPAIP_01061 7e-36
LEHHPAIP_01062 3.3e-127 IQ Dehydrogenase reductase
LEHHPAIP_01063 4.9e-238 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
LEHHPAIP_01064 1.9e-18 3.2.1.18 GH33 M Rib/alpha-like repeat
LEHHPAIP_01065 3.4e-121 L Helix-turn-helix domain
LEHHPAIP_01066 7.9e-123 O Zinc-dependent metalloprotease
LEHHPAIP_01067 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEHHPAIP_01068 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
LEHHPAIP_01071 5e-237 L Integrase core domain
LEHHPAIP_01072 3.2e-130 O Bacterial dnaA protein
LEHHPAIP_01073 8e-153 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
LEHHPAIP_01074 3.8e-85 yxjG_1 E methionine synthase, vitamin-B12 independent
LEHHPAIP_01075 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
LEHHPAIP_01076 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEHHPAIP_01077 8e-134 D nuclear chromosome segregation
LEHHPAIP_01078 0.0 lacZ 3.2.1.23 G -beta-galactosidase
LEHHPAIP_01079 0.0 lacS G Transporter
LEHHPAIP_01080 3e-187 lacR K Transcriptional regulator
LEHHPAIP_01081 3.8e-10
LEHHPAIP_01082 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
LEHHPAIP_01083 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
LEHHPAIP_01084 8.5e-34
LEHHPAIP_01085 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEHHPAIP_01086 9.9e-261 yfnA E amino acid
LEHHPAIP_01087 2.2e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LEHHPAIP_01088 7.6e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEHHPAIP_01089 4.1e-40 ylqC S Belongs to the UPF0109 family
LEHHPAIP_01090 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LEHHPAIP_01091 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEHHPAIP_01092 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEHHPAIP_01093 1.1e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEHHPAIP_01094 0.0 smc D Required for chromosome condensation and partitioning
LEHHPAIP_01095 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEHHPAIP_01096 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEHHPAIP_01097 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEHHPAIP_01098 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEHHPAIP_01099 0.0 yloV S DAK2 domain fusion protein YloV
LEHHPAIP_01100 4.7e-58 asp S Asp23 family, cell envelope-related function
LEHHPAIP_01101 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LEHHPAIP_01102 2.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
LEHHPAIP_01103 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LEHHPAIP_01104 1.5e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEHHPAIP_01105 0.0 KLT serine threonine protein kinase
LEHHPAIP_01106 6.1e-129 stp 3.1.3.16 T phosphatase
LEHHPAIP_01107 2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEHHPAIP_01108 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEHHPAIP_01109 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEHHPAIP_01110 1.3e-208 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEHHPAIP_01111 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEHHPAIP_01112 7.9e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LEHHPAIP_01113 4.2e-53
LEHHPAIP_01114 6.1e-262 recN L May be involved in recombinational repair of damaged DNA
LEHHPAIP_01115 7.3e-77 argR K Regulates arginine biosynthesis genes
LEHHPAIP_01116 1.2e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LEHHPAIP_01117 4.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEHHPAIP_01118 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEHHPAIP_01119 2.6e-215 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEHHPAIP_01120 1.3e-146 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEHHPAIP_01121 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEHHPAIP_01122 2.2e-70 yqhY S Asp23 family, cell envelope-related function
LEHHPAIP_01123 1.7e-114 J 2'-5' RNA ligase superfamily
LEHHPAIP_01124 7.3e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LEHHPAIP_01125 2.6e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LEHHPAIP_01126 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LEHHPAIP_01127 2.4e-53 ysxB J Cysteine protease Prp
LEHHPAIP_01128 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
LEHHPAIP_01129 7e-110 K Transcriptional regulator
LEHHPAIP_01132 5.7e-86 dut S Protein conserved in bacteria
LEHHPAIP_01133 3e-179
LEHHPAIP_01134 9.7e-150
LEHHPAIP_01135 4.8e-51 S Iron-sulfur cluster assembly protein
LEHHPAIP_01136 4.7e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEHHPAIP_01137 3.9e-12
LEHHPAIP_01138 2.3e-41 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
LEHHPAIP_01139 6.1e-32 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
LEHHPAIP_01140 3.9e-96 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
LEHHPAIP_01141 2.2e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEHHPAIP_01142 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
LEHHPAIP_01143 2e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEHHPAIP_01144 5.9e-22 S Protein of unknown function (DUF3042)
LEHHPAIP_01145 3.4e-67 yqhL P Rhodanese-like protein
LEHHPAIP_01146 5.6e-183 glk 2.7.1.2 G Glucokinase
LEHHPAIP_01147 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
LEHHPAIP_01148 1.6e-19 gluP 3.4.21.105 S Peptidase, S54 family
LEHHPAIP_01149 1.6e-74 gluP 3.4.21.105 S Peptidase, S54 family
LEHHPAIP_01150 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEHHPAIP_01151 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEHHPAIP_01152 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
LEHHPAIP_01153 0.0 S membrane
LEHHPAIP_01154 3.1e-68 yneR S Belongs to the HesB IscA family
LEHHPAIP_01155 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEHHPAIP_01156 2.3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
LEHHPAIP_01157 3.6e-114 rlpA M PFAM NLP P60 protein
LEHHPAIP_01158 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEHHPAIP_01159 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEHHPAIP_01160 4.4e-58 yodB K Transcriptional regulator, HxlR family
LEHHPAIP_01161 1.2e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEHHPAIP_01162 4.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEHHPAIP_01163 1.6e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LEHHPAIP_01164 1.3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEHHPAIP_01165 8.2e-67 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LEHHPAIP_01166 4.3e-234 V MatE
LEHHPAIP_01167 4.8e-266 yjeM E Amino Acid
LEHHPAIP_01168 3.7e-279 arlS 2.7.13.3 T Histidine kinase
LEHHPAIP_01169 1.5e-121 K response regulator
LEHHPAIP_01170 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LEHHPAIP_01171 2.9e-99 yceD S Uncharacterized ACR, COG1399
LEHHPAIP_01172 1.5e-208 ylbM S Belongs to the UPF0348 family
LEHHPAIP_01173 1.1e-135 yqeM Q Methyltransferase
LEHHPAIP_01174 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEHHPAIP_01175 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
LEHHPAIP_01176 6.9e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEHHPAIP_01177 1.9e-47 yhbY J RNA-binding protein
LEHHPAIP_01178 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
LEHHPAIP_01179 1.4e-95 yqeG S HAD phosphatase, family IIIA
LEHHPAIP_01180 5.6e-84
LEHHPAIP_01182 1.3e-197 L Belongs to the 'phage' integrase family
LEHHPAIP_01183 2.3e-22 S DNA binding domain, excisionase family
LEHHPAIP_01184 4.3e-09
LEHHPAIP_01186 6.1e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LEHHPAIP_01187 9.2e-59 L Resolvase, N terminal domain
LEHHPAIP_01188 4e-12 L Resolvase, N terminal domain
LEHHPAIP_01189 2.7e-08 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LEHHPAIP_01191 4.3e-155 L Helix-turn-helix domain
LEHHPAIP_01192 1.7e-32 3.2.1.18 GH33 M Rib/alpha-like repeat
LEHHPAIP_01193 6.3e-38 ykuJ S Protein of unknown function (DUF1797)
LEHHPAIP_01194 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEHHPAIP_01195 1.5e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
LEHHPAIP_01196 4.6e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LEHHPAIP_01197 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEHHPAIP_01198 2.7e-39 ptsH G phosphocarrier protein HPR
LEHHPAIP_01199 6.4e-27
LEHHPAIP_01200 0.0 clpE O Belongs to the ClpA ClpB family
LEHHPAIP_01201 1.7e-100 S Pfam:DUF3816
LEHHPAIP_01202 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
LEHHPAIP_01203 5.5e-116
LEHHPAIP_01204 4.4e-155 V ABC transporter, ATP-binding protein
LEHHPAIP_01205 6e-64 gntR1 K Transcriptional regulator, GntR family
LEHHPAIP_01206 0.0 bamA GM domain, Protein
LEHHPAIP_01207 0.0 S Peptidase, M23
LEHHPAIP_01208 0.0 M NlpC/P60 family
LEHHPAIP_01209 1.2e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LEHHPAIP_01210 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LEHHPAIP_01211 7.4e-163 yueF S AI-2E family transporter
LEHHPAIP_01212 0.0 csd1 3.5.1.28 G domain, Protein
LEHHPAIP_01213 1.6e-109 dedA S SNARE-like domain protein
LEHHPAIP_01214 2.8e-101 S Protein of unknown function (DUF1461)
LEHHPAIP_01215 5.5e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEHHPAIP_01216 6.6e-93 yutD S Protein of unknown function (DUF1027)
LEHHPAIP_01217 4.7e-111 S Calcineurin-like phosphoesterase
LEHHPAIP_01218 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEHHPAIP_01219 7.9e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
LEHHPAIP_01221 1.2e-68
LEHHPAIP_01222 3.2e-41
LEHHPAIP_01223 3.4e-79 NU general secretion pathway protein
LEHHPAIP_01224 7.1e-47 comGC U competence protein ComGC
LEHHPAIP_01225 5.1e-182 comGB NU type II secretion system
LEHHPAIP_01226 4.9e-179 comGA NU Type II IV secretion system protein
LEHHPAIP_01227 5.9e-132 yebC K Transcriptional regulatory protein
LEHHPAIP_01228 3.3e-131
LEHHPAIP_01229 7.1e-181 ccpA K catabolite control protein A
LEHHPAIP_01230 3.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LEHHPAIP_01231 3e-25
LEHHPAIP_01232 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEHHPAIP_01233 3.4e-147 ykuT M mechanosensitive ion channel
LEHHPAIP_01234 1.8e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
LEHHPAIP_01235 1.1e-74 ykuL S (CBS) domain
LEHHPAIP_01236 1.7e-93 S Phosphoesterase
LEHHPAIP_01237 3.7e-105 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEHHPAIP_01238 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LEHHPAIP_01239 3e-96 yslB S Protein of unknown function (DUF2507)
LEHHPAIP_01240 6.1e-54 trxA O Belongs to the thioredoxin family
LEHHPAIP_01241 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEHHPAIP_01242 2.7e-86 cvpA S Colicin V production protein
LEHHPAIP_01243 6.1e-48 yrzB S Belongs to the UPF0473 family
LEHHPAIP_01244 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEHHPAIP_01245 4.1e-43 yrzL S Belongs to the UPF0297 family
LEHHPAIP_01246 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEHHPAIP_01247 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEHHPAIP_01248 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
LEHHPAIP_01249 6.2e-31 yajC U Preprotein translocase
LEHHPAIP_01250 1.7e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEHHPAIP_01251 1.3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEHHPAIP_01252 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEHHPAIP_01253 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEHHPAIP_01254 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEHHPAIP_01255 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
LEHHPAIP_01256 1.7e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEHHPAIP_01257 8.1e-227 cinA 3.5.1.42 S Belongs to the CinA family
LEHHPAIP_01258 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEHHPAIP_01259 1.2e-135 ymfM S Helix-turn-helix domain
LEHHPAIP_01260 2.3e-248 ymfH S Peptidase M16
LEHHPAIP_01261 5.3e-226 ymfF S Peptidase M16 inactive domain protein
LEHHPAIP_01262 2.5e-158 aatB ET ABC transporter substrate-binding protein
LEHHPAIP_01263 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEHHPAIP_01264 3.2e-102 glnP P ABC transporter permease
LEHHPAIP_01265 8.7e-93 mreD M rod shape-determining protein MreD
LEHHPAIP_01266 3.5e-152 mreC M Involved in formation and maintenance of cell shape
LEHHPAIP_01267 1.7e-179 mreB D cell shape determining protein MreB
LEHHPAIP_01268 1.8e-121 radC L DNA repair protein
LEHHPAIP_01269 7.2e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LEHHPAIP_01270 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
LEHHPAIP_01271 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LEHHPAIP_01272 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LEHHPAIP_01273 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
LEHHPAIP_01274 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
LEHHPAIP_01275 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEHHPAIP_01276 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEHHPAIP_01277 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
LEHHPAIP_01278 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEHHPAIP_01279 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEHHPAIP_01280 1.3e-72 L PFAM Integrase catalytic region
LEHHPAIP_01281 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
LEHHPAIP_01282 1.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEHHPAIP_01283 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
LEHHPAIP_01284 3.1e-113 yjbH Q Thioredoxin
LEHHPAIP_01285 1.4e-267 pipD E Dipeptidase
LEHHPAIP_01286 2.6e-194 coiA 3.6.4.12 S Competence protein
LEHHPAIP_01287 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LEHHPAIP_01288 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEHHPAIP_01289 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LEHHPAIP_01290 6.1e-181 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
LEHHPAIP_01291 5.3e-124 repE K Primase C terminal 1 (PriCT-1)
LEHHPAIP_01293 1.8e-11 S Thioredoxin
LEHHPAIP_01295 9.7e-07
LEHHPAIP_01296 2.3e-27
LEHHPAIP_01301 9.5e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LEHHPAIP_01303 9.3e-29 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
LEHHPAIP_01305 6.7e-11
LEHHPAIP_01306 3.4e-125 ruvB 3.6.4.12 L four-way junction helicase activity
LEHHPAIP_01310 1.9e-76
LEHHPAIP_01314 1.8e-194 traI 5.99.1.2 L C-terminal repeat of topoisomerase
LEHHPAIP_01318 3.9e-188 clpB O Belongs to the ClpA ClpB family
LEHHPAIP_01321 2.5e-16
LEHHPAIP_01322 4e-264 U COG3505 Type IV secretory pathway, VirD4 components
LEHHPAIP_01323 2.7e-89
LEHHPAIP_01325 3e-23 D nuclear chromosome segregation
LEHHPAIP_01329 5e-29 3.4.22.70 M Sortase family
LEHHPAIP_01330 5.6e-85 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
LEHHPAIP_01331 4.7e-43 3.4.22.70 M Sortase family
LEHHPAIP_01335 1.9e-30 higB-2 S RelE toxin of RelE / RelB toxin-antitoxin system
LEHHPAIP_01336 3.8e-21 K Helix-turn-helix XRE-family like proteins
LEHHPAIP_01339 3.3e-21 ssb L Single-stranded DNA-binding protein
LEHHPAIP_01346 3e-08
LEHHPAIP_01348 6.9e-67 L transposase, IS605 OrfB family
LEHHPAIP_01350 1.1e-86 endA F DNA RNA non-specific endonuclease
LEHHPAIP_01353 3e-126 NU StbA protein
LEHHPAIP_01355 5.2e-07 S Uncharacterized protein pXO2-11
LEHHPAIP_01356 9.7e-38
LEHHPAIP_01357 4.2e-230 trsE S COG0433 Predicted ATPase
LEHHPAIP_01359 1.2e-28 M CHAP domain
LEHHPAIP_01361 1.8e-07
LEHHPAIP_01362 1.7e-100 S Uncharacterised protein family (UPF0236)
LEHHPAIP_01363 3.9e-14 S enterobacterial common antigen metabolic process
LEHHPAIP_01364 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
LEHHPAIP_01365 8e-153 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
LEHHPAIP_01366 2.4e-22
LEHHPAIP_01367 2.9e-96 K Acetyltransferase (GNAT) domain
LEHHPAIP_01368 1.7e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
LEHHPAIP_01369 7.8e-16 gntT EG Gluconate
LEHHPAIP_01370 2.7e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
LEHHPAIP_01371 1.9e-11 T PFAM SpoVT AbrB
LEHHPAIP_01372 2.2e-176 M Glycosyl hydrolases family 25
LEHHPAIP_01373 2.6e-45 S Bacteriophage holin of superfamily 6 (Holin_LLH)
LEHHPAIP_01374 1.3e-31
LEHHPAIP_01376 1e-11 S by MetaGeneAnnotator
LEHHPAIP_01380 5.2e-41 S Domain of unknown function (DUF2479)
LEHHPAIP_01383 9.9e-21 M CHAP domain
LEHHPAIP_01384 0.0 tetP J elongation factor G
LEHHPAIP_01385 3e-69 S Conjugative transposon protein TcpC
LEHHPAIP_01388 5.2e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
LEHHPAIP_01389 8.3e-34
LEHHPAIP_01390 3.6e-07 L Resolvase, N terminal domain
LEHHPAIP_01391 1.9e-185 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
LEHHPAIP_01392 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
LEHHPAIP_01393 1.6e-42 hxlR K Transcriptional regulator, HxlR family
LEHHPAIP_01394 7.5e-162 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LEHHPAIP_01395 2.4e-71 K Helix-turn-helix domain
LEHHPAIP_01397 6e-93 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
LEHHPAIP_01398 3.7e-31 S Protein of unknown function (DUF2089)
LEHHPAIP_01399 9.3e-28
LEHHPAIP_01402 5.7e-90 L Integrase
LEHHPAIP_01404 2.8e-162 lsa S ABC transporter
LEHHPAIP_01405 3e-133 I alpha/beta hydrolase fold
LEHHPAIP_01406 4e-179 MA20_14895 S Conserved hypothetical protein 698
LEHHPAIP_01407 1.2e-94 S NADPH-dependent FMN reductase
LEHHPAIP_01408 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEHHPAIP_01409 1.4e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LEHHPAIP_01410 1.4e-229 mntH P H( )-stimulated, divalent metal cation uptake system
LEHHPAIP_01411 1e-77 Q Methyltransferase
LEHHPAIP_01412 7.7e-115 ktrA P domain protein
LEHHPAIP_01413 4.5e-239 ktrB P Potassium uptake protein
LEHHPAIP_01414 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
LEHHPAIP_01415 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LEHHPAIP_01416 1e-223 G Glycosyl hydrolases family 8
LEHHPAIP_01417 8.5e-243 ydaM M Glycosyl transferase
LEHHPAIP_01418 3.3e-142
LEHHPAIP_01419 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
LEHHPAIP_01420 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEHHPAIP_01421 2.6e-155 pstA P Phosphate transport system permease protein PstA
LEHHPAIP_01422 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
LEHHPAIP_01423 1.1e-158 pstS P Phosphate
LEHHPAIP_01424 3.6e-131 K Transcriptional regulatory protein, C-terminal domain protein
LEHHPAIP_01425 9.7e-20 L Transposase
LEHHPAIP_01426 1.3e-145 L Transposase
LEHHPAIP_01427 3.2e-39 L Transposase
LEHHPAIP_01428 2.2e-16 K Transcriptional regulator, HxlR family
LEHHPAIP_01429 3.9e-187
LEHHPAIP_01430 1.2e-97 2.3.1.128 K acetyltransferase
LEHHPAIP_01431 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
LEHHPAIP_01432 8.2e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
LEHHPAIP_01433 1.3e-53 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEHHPAIP_01434 3.9e-182
LEHHPAIP_01435 4.2e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEHHPAIP_01436 1.7e-183 S Phosphotransferase system, EIIC
LEHHPAIP_01437 3e-27 L PFAM transposase IS200-family protein
LEHHPAIP_01439 6.3e-37 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LEHHPAIP_01440 6.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEHHPAIP_01441 2e-264 glnP P ABC transporter
LEHHPAIP_01442 5.5e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEHHPAIP_01443 1.4e-219 cycA E Amino acid permease
LEHHPAIP_01444 1.3e-218 nupG F Nucleoside transporter
LEHHPAIP_01445 3.3e-169 rihC 3.2.2.1 F Nucleoside
LEHHPAIP_01446 2.7e-160 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
LEHHPAIP_01447 9.2e-122 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
LEHHPAIP_01448 1.8e-144 noc K Belongs to the ParB family
LEHHPAIP_01449 3.6e-140 soj D Sporulation initiation inhibitor
LEHHPAIP_01450 1.9e-153 spo0J K Belongs to the ParB family
LEHHPAIP_01451 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
LEHHPAIP_01452 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEHHPAIP_01453 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
LEHHPAIP_01454 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEHHPAIP_01455 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LEHHPAIP_01456 2.1e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
LEHHPAIP_01457 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LEHHPAIP_01458 1.2e-169 deoR K sugar-binding domain protein
LEHHPAIP_01459 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEHHPAIP_01460 3.8e-125 K response regulator
LEHHPAIP_01461 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
LEHHPAIP_01462 2.3e-138 azlC E AzlC protein
LEHHPAIP_01463 1.6e-52 azlD S branched-chain amino acid
LEHHPAIP_01464 6.6e-124 K LysR substrate binding domain
LEHHPAIP_01465 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LEHHPAIP_01466 2.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEHHPAIP_01467 3.3e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEHHPAIP_01468 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEHHPAIP_01469 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEHHPAIP_01470 1.1e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
LEHHPAIP_01471 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LEHHPAIP_01472 1.8e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LEHHPAIP_01473 6.6e-174 K AI-2E family transporter
LEHHPAIP_01474 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LEHHPAIP_01475 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LEHHPAIP_01476 4.5e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
LEHHPAIP_01477 2.7e-24 K helix_turn_helix, arabinose operon control protein
LEHHPAIP_01478 3.4e-187 thrC 4.2.3.1 E Threonine synthase
LEHHPAIP_01479 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LEHHPAIP_01480 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEHHPAIP_01481 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEHHPAIP_01482 1.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEHHPAIP_01483 8.9e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEHHPAIP_01484 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LEHHPAIP_01485 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEHHPAIP_01486 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEHHPAIP_01487 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEHHPAIP_01488 2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEHHPAIP_01489 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LEHHPAIP_01490 8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEHHPAIP_01491 1.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LEHHPAIP_01492 2.8e-243 purD 6.3.4.13 F Belongs to the GARS family
LEHHPAIP_01493 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEHHPAIP_01494 1.8e-166
LEHHPAIP_01495 5.4e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEHHPAIP_01496 6.4e-90 L Transposase IS66 family
LEHHPAIP_01497 5.3e-40 L Transposase IS66 family
LEHHPAIP_01500 1.3e-263 dtpT U amino acid peptide transporter
LEHHPAIP_01501 2.7e-149 yjjH S Calcineurin-like phosphoesterase
LEHHPAIP_01504 1e-111
LEHHPAIP_01505 3.2e-248 EGP Major facilitator Superfamily
LEHHPAIP_01506 1.6e-299 aspT P Predicted Permease Membrane Region
LEHHPAIP_01507 2.4e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LEHHPAIP_01508 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
LEHHPAIP_01509 6.9e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEHHPAIP_01510 4.4e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEHHPAIP_01511 0.0 yhgF K Tex-like protein N-terminal domain protein
LEHHPAIP_01512 1.5e-82 ydcK S Belongs to the SprT family
LEHHPAIP_01514 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
LEHHPAIP_01515 2.2e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
LEHHPAIP_01516 0.0 S Bacterial membrane protein, YfhO
LEHHPAIP_01517 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEHHPAIP_01518 3.8e-167 I alpha/beta hydrolase fold
LEHHPAIP_01519 2.9e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LEHHPAIP_01520 1.1e-119 tcyB E ABC transporter
LEHHPAIP_01521 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEHHPAIP_01522 4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LEHHPAIP_01523 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
LEHHPAIP_01524 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEHHPAIP_01525 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
LEHHPAIP_01526 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
LEHHPAIP_01527 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEHHPAIP_01528 1.1e-204 yacL S domain protein
LEHHPAIP_01529 1.3e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEHHPAIP_01530 4.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEHHPAIP_01531 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEHHPAIP_01532 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEHHPAIP_01533 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEHHPAIP_01534 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
LEHHPAIP_01535 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEHHPAIP_01536 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEHHPAIP_01537 2.8e-224 aadAT EK Aminotransferase, class I
LEHHPAIP_01539 1.8e-32 M Glycosyl transferase family group 2
LEHHPAIP_01540 6.3e-154 M Glycosyl transferase family group 2
LEHHPAIP_01541 4e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEHHPAIP_01542 3.8e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEHHPAIP_01543 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEHHPAIP_01544 4.8e-34
LEHHPAIP_01545 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEHHPAIP_01546 2.4e-56 K transcriptional regulator PadR family
LEHHPAIP_01547 8.7e-81 XK27_06920 S Protein of unknown function (DUF1700)
LEHHPAIP_01548 3.2e-133 S Putative adhesin
LEHHPAIP_01549 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LEHHPAIP_01550 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEHHPAIP_01551 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEHHPAIP_01552 3.4e-35 nrdH O Glutaredoxin
LEHHPAIP_01553 5.2e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEHHPAIP_01554 7.6e-290 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEHHPAIP_01555 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEHHPAIP_01556 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEHHPAIP_01557 1.1e-37 S Protein of unknown function (DUF2508)
LEHHPAIP_01558 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEHHPAIP_01559 2.9e-51 yaaQ S Cyclic-di-AMP receptor
LEHHPAIP_01560 1.7e-182 holB 2.7.7.7 L DNA polymerase III
LEHHPAIP_01561 3.1e-43 yabA L Involved in initiation control of chromosome replication
LEHHPAIP_01562 7.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEHHPAIP_01563 8.4e-134 fat 3.1.2.21 I Acyl-ACP thioesterase
LEHHPAIP_01564 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
LEHHPAIP_01565 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LEHHPAIP_01566 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
LEHHPAIP_01567 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LEHHPAIP_01569 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
LEHHPAIP_01570 9.9e-69 L Transposase IS66 family
LEHHPAIP_01571 4.2e-109 L Bacterial dnaA protein
LEHHPAIP_01572 2.6e-137 L Integrase core domain
LEHHPAIP_01573 2.8e-188 L Transposase IS66 family
LEHHPAIP_01574 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
LEHHPAIP_01576 5e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LEHHPAIP_01577 1.4e-158 rrmA 2.1.1.187 H Methyltransferase
LEHHPAIP_01578 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEHHPAIP_01579 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LEHHPAIP_01580 1.2e-10 S Protein of unknown function (DUF4044)
LEHHPAIP_01581 1.7e-57
LEHHPAIP_01582 3.1e-77 mraZ K Belongs to the MraZ family
LEHHPAIP_01583 8.8e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEHHPAIP_01584 2.9e-55 ftsL D Cell division protein FtsL
LEHHPAIP_01585 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LEHHPAIP_01586 4.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEHHPAIP_01587 4.2e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEHHPAIP_01588 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEHHPAIP_01589 2.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEHHPAIP_01590 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEHHPAIP_01591 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEHHPAIP_01592 2.1e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEHHPAIP_01593 3.2e-40 yggT S YGGT family
LEHHPAIP_01594 2.4e-144 ylmH S S4 domain protein
LEHHPAIP_01595 1.3e-35 divIVA D DivIVA domain protein
LEHHPAIP_01596 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEHHPAIP_01597 4.2e-32 cspA K Cold shock protein
LEHHPAIP_01598 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
LEHHPAIP_01600 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEHHPAIP_01601 1.6e-216 iscS 2.8.1.7 E Aminotransferase class V
LEHHPAIP_01602 7.5e-58 XK27_04120 S Putative amino acid metabolism
LEHHPAIP_01603 6.9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEHHPAIP_01604 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
LEHHPAIP_01605 4.9e-117 S Repeat protein
LEHHPAIP_01606 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEHHPAIP_01607 6.9e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEHHPAIP_01608 7.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEHHPAIP_01609 6.7e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
LEHHPAIP_01610 1.5e-244 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEHHPAIP_01611 7e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEHHPAIP_01612 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEHHPAIP_01613 2.9e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEHHPAIP_01614 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEHHPAIP_01615 7.7e-219 patA 2.6.1.1 E Aminotransferase
LEHHPAIP_01616 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEHHPAIP_01617 8.5e-84 KT Putative sugar diacid recognition
LEHHPAIP_01618 4.2e-218 EG GntP family permease
LEHHPAIP_01619 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LEHHPAIP_01620 2.2e-57
LEHHPAIP_01622 1.7e-122 mltD CBM50 M NlpC P60 family protein
LEHHPAIP_01623 5.7e-29
LEHHPAIP_01624 1.9e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
LEHHPAIP_01625 9.8e-32 ykzG S Belongs to the UPF0356 family
LEHHPAIP_01626 4.8e-79
LEHHPAIP_01627 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEHHPAIP_01628 5.3e-124 repE K Primase C terminal 1 (PriCT-1)
LEHHPAIP_01630 1.8e-11 S Thioredoxin
LEHHPAIP_01632 9.7e-07
LEHHPAIP_01633 2.3e-27
LEHHPAIP_01638 9.5e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LEHHPAIP_01640 9.3e-29 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
LEHHPAIP_01642 6.7e-11
LEHHPAIP_01643 3.4e-125 ruvB 3.6.4.12 L four-way junction helicase activity
LEHHPAIP_01647 1.9e-76
LEHHPAIP_01651 1.8e-194 traI 5.99.1.2 L C-terminal repeat of topoisomerase
LEHHPAIP_01655 3.9e-188 clpB O Belongs to the ClpA ClpB family
LEHHPAIP_01658 2.5e-16
LEHHPAIP_01659 4e-264 U COG3505 Type IV secretory pathway, VirD4 components
LEHHPAIP_01660 2.7e-89
LEHHPAIP_01662 3e-23 D nuclear chromosome segregation
LEHHPAIP_01666 5e-29 3.4.22.70 M Sortase family
LEHHPAIP_01667 5.6e-85 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
LEHHPAIP_01668 4.7e-43 3.4.22.70 M Sortase family
LEHHPAIP_01672 1.9e-30 higB-2 S RelE toxin of RelE / RelB toxin-antitoxin system
LEHHPAIP_01673 3.8e-21 K Helix-turn-helix XRE-family like proteins
LEHHPAIP_01676 3.3e-21 ssb L Single-stranded DNA-binding protein
LEHHPAIP_01683 3e-08
LEHHPAIP_01685 6.9e-67 L transposase, IS605 OrfB family
LEHHPAIP_01687 1.1e-86 endA F DNA RNA non-specific endonuclease
LEHHPAIP_01690 3e-126 NU StbA protein
LEHHPAIP_01692 5.2e-07 S Uncharacterized protein pXO2-11
LEHHPAIP_01693 9.7e-38
LEHHPAIP_01694 4.2e-230 trsE S COG0433 Predicted ATPase
LEHHPAIP_01696 1.2e-28 M CHAP domain
LEHHPAIP_01698 1.8e-07
LEHHPAIP_01699 1.7e-100 S Uncharacterised protein family (UPF0236)
LEHHPAIP_01700 1.6e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEHHPAIP_01701 4.2e-49 ebh D nuclear chromosome segregation
LEHHPAIP_01702 4.4e-48 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEHHPAIP_01703 1.9e-134 L hmm pf00665
LEHHPAIP_01704 3.3e-71 L Helix-turn-helix domain
LEHHPAIP_01705 6.3e-257 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LEHHPAIP_01706 3.8e-182 pbuG S permease
LEHHPAIP_01707 1.4e-163 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LEHHPAIP_01708 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LEHHPAIP_01709 2.5e-258 G Major Facilitator Superfamily
LEHHPAIP_01710 1.8e-34 2.1.1.72 V Type II restriction enzyme, methylase subunits
LEHHPAIP_01711 2e-109 2.1.1.72 V Type II restriction enzyme, methylase subunits
LEHHPAIP_01712 1.3e-224 oxlT P Major Facilitator Superfamily
LEHHPAIP_01713 8.6e-159 spoU 2.1.1.185 J Methyltransferase
LEHHPAIP_01714 1.3e-18 ywlG S Belongs to the UPF0340 family
LEHHPAIP_01715 1.3e-48 S ParE toxin of type II toxin-antitoxin system, parDE
LEHHPAIP_01716 1e-37 D Antitoxin component of a toxin-antitoxin (TA) module
LEHHPAIP_01717 1.2e-179 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
LEHHPAIP_01718 1e-108 mmuP E amino acid
LEHHPAIP_01720 7.4e-67 T Toxin-antitoxin system, toxin component, MazF family
LEHHPAIP_01721 5.2e-37
LEHHPAIP_01722 6.7e-07 D nuclear chromosome segregation
LEHHPAIP_01723 0.0 snf 2.7.11.1 KL domain protein
LEHHPAIP_01724 1e-142 ywqE 3.1.3.48 GM PHP domain protein
LEHHPAIP_01725 6.8e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LEHHPAIP_01726 0.0 sbcC L Putative exonuclease SbcCD, C subunit
LEHHPAIP_01727 0.0 2.7.7.6 M Peptidase family M23
LEHHPAIP_01728 2.1e-117 rfbP 2.7.8.6 M Bacterial sugar transferase
LEHHPAIP_01729 1e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
LEHHPAIP_01730 1.9e-146 cps1D M Domain of unknown function (DUF4422)
LEHHPAIP_01731 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
LEHHPAIP_01732 4.9e-31
LEHHPAIP_01733 6.6e-34 S Protein of unknown function (DUF2922)
LEHHPAIP_01734 1.8e-143 yihY S Belongs to the UPF0761 family
LEHHPAIP_01735 3.4e-280 yjeM E Amino Acid
LEHHPAIP_01736 9.5e-256 E Arginine ornithine antiporter
LEHHPAIP_01737 1.6e-221 arcT 2.6.1.1 E Aminotransferase
LEHHPAIP_01738 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
LEHHPAIP_01739 1.4e-78 fld C Flavodoxin
LEHHPAIP_01740 1.3e-67 gtcA S Teichoic acid glycosylation protein
LEHHPAIP_01741 7.1e-56
LEHHPAIP_01742 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEHHPAIP_01744 1.9e-231 yfmL L DEAD DEAH box helicase
LEHHPAIP_01745 5.9e-191 mocA S Oxidoreductase
LEHHPAIP_01746 9.1e-62 S Domain of unknown function (DUF4828)
LEHHPAIP_01747 1.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
LEHHPAIP_01748 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LEHHPAIP_01749 2.2e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
LEHHPAIP_01750 3e-195 S Protein of unknown function (DUF3114)
LEHHPAIP_01751 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
LEHHPAIP_01752 7.3e-116 ybhL S Belongs to the BI1 family
LEHHPAIP_01753 1.9e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEHHPAIP_01754 7.8e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEHHPAIP_01755 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LEHHPAIP_01756 9.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEHHPAIP_01757 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEHHPAIP_01758 1.8e-134
LEHHPAIP_01759 1.2e-145 rfbJ M Glycosyl transferase family 2
LEHHPAIP_01760 5.8e-83
LEHHPAIP_01761 2e-72 S Acyltransferase family
LEHHPAIP_01762 1.3e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
LEHHPAIP_01763 1.8e-67 S Glycosyltransferase like family
LEHHPAIP_01764 3.4e-76 rgpB GT2 M Glycosyl transferase family 2
LEHHPAIP_01765 3.9e-28 M biosynthesis protein
LEHHPAIP_01766 3.1e-90 cps3F
LEHHPAIP_01767 4.7e-76 M transferase activity, transferring glycosyl groups
LEHHPAIP_01768 3.2e-211 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
LEHHPAIP_01769 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
LEHHPAIP_01770 6.1e-25
LEHHPAIP_01771 0.0 G Peptidase_C39 like family
LEHHPAIP_01772 1.8e-99 glsA 3.5.1.2 E Belongs to the glutaminase family
LEHHPAIP_01773 4.5e-55 glsA 3.5.1.2 E Belongs to the glutaminase family
LEHHPAIP_01774 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEHHPAIP_01775 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHHPAIP_01776 1.1e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
LEHHPAIP_01777 2.2e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHHPAIP_01779 1.1e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEHHPAIP_01780 2e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEHHPAIP_01781 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
LEHHPAIP_01782 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
LEHHPAIP_01783 2.3e-242 codA 3.5.4.1 F cytosine deaminase
LEHHPAIP_01784 6.4e-145 tesE Q hydratase
LEHHPAIP_01785 0.0 FbpA K Fibronectin-binding protein
LEHHPAIP_01786 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LEHHPAIP_01787 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
LEHHPAIP_01788 2.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEHHPAIP_01789 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEHHPAIP_01790 5.6e-65 esbA S Family of unknown function (DUF5322)
LEHHPAIP_01791 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
LEHHPAIP_01792 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LEHHPAIP_01793 4e-81 F Belongs to the NrdI family
LEHHPAIP_01794 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEHHPAIP_01795 3.2e-101 ypsA S Belongs to the UPF0398 family
LEHHPAIP_01796 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEHHPAIP_01797 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
LEHHPAIP_01798 1.3e-160 EG EamA-like transporter family
LEHHPAIP_01799 8.1e-123 dnaD L DnaD domain protein
LEHHPAIP_01800 9.9e-86 ypmB S Protein conserved in bacteria
LEHHPAIP_01801 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LEHHPAIP_01802 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LEHHPAIP_01803 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LEHHPAIP_01804 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LEHHPAIP_01805 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEHHPAIP_01806 9.3e-86 S Protein of unknown function (DUF1440)
LEHHPAIP_01807 4.9e-160 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LEHHPAIP_01808 8.7e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEHHPAIP_01809 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEHHPAIP_01810 2e-158 htpX O Belongs to the peptidase M48B family
LEHHPAIP_01811 7e-93 lemA S LemA family
LEHHPAIP_01812 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEHHPAIP_01813 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LEHHPAIP_01814 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
LEHHPAIP_01815 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEHHPAIP_01816 2.3e-158 3.2.1.55 GH51 G Right handed beta helix region
LEHHPAIP_01817 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
LEHHPAIP_01818 7.3e-116 srtA 3.4.22.70 M sortase family
LEHHPAIP_01819 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
LEHHPAIP_01820 4.5e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEHHPAIP_01821 4.6e-41 rpmE2 J Ribosomal protein L31
LEHHPAIP_01822 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEHHPAIP_01823 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEHHPAIP_01824 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEHHPAIP_01825 8.2e-67 ywiB S Domain of unknown function (DUF1934)
LEHHPAIP_01826 4.1e-159 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LEHHPAIP_01827 2.1e-160 degV S EDD domain protein, DegV family
LEHHPAIP_01828 1.1e-89
LEHHPAIP_01829 1.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEHHPAIP_01830 8.7e-156 gspA M family 8
LEHHPAIP_01831 1.1e-153 S Alpha beta hydrolase
LEHHPAIP_01832 1.5e-94 K Acetyltransferase (GNAT) domain
LEHHPAIP_01833 8.7e-243 XK27_08635 S UPF0210 protein
LEHHPAIP_01834 1.4e-38 gcvR T Belongs to the UPF0237 family
LEHHPAIP_01835 1.7e-170 1.1.1.346 C Aldo keto reductase
LEHHPAIP_01836 1.5e-158 K LysR substrate binding domain protein
LEHHPAIP_01837 2.6e-77 C Flavodoxin
LEHHPAIP_01838 1.5e-77 yphH S Cupin domain
LEHHPAIP_01839 1.7e-73 yeaL S UPF0756 membrane protein
LEHHPAIP_01840 6.2e-244 EGP Major facilitator Superfamily
LEHHPAIP_01841 5e-75 copY K Copper transport repressor CopY TcrY
LEHHPAIP_01842 8.5e-246 yhdP S Transporter associated domain
LEHHPAIP_01843 0.0 ubiB S ABC1 family
LEHHPAIP_01844 1.5e-144 S DUF218 domain
LEHHPAIP_01845 2.1e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEHHPAIP_01846 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEHHPAIP_01847 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEHHPAIP_01848 0.0 uvrA3 L excinuclease ABC, A subunit
LEHHPAIP_01849 3.7e-120 S SNARE associated Golgi protein
LEHHPAIP_01850 2.3e-229 N Uncharacterized conserved protein (DUF2075)
LEHHPAIP_01851 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEHHPAIP_01853 6.6e-254 yifK E Amino acid permease
LEHHPAIP_01854 7.2e-158 endA V DNA/RNA non-specific endonuclease
LEHHPAIP_01855 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEHHPAIP_01856 2.3e-41 ybaN S Protein of unknown function (DUF454)
LEHHPAIP_01857 1.6e-71 S Protein of unknown function (DUF3290)
LEHHPAIP_01858 4.7e-114 yviA S Protein of unknown function (DUF421)
LEHHPAIP_01859 2.2e-162 S Alpha/beta hydrolase of unknown function (DUF915)
LEHHPAIP_01860 2e-18
LEHHPAIP_01861 2.1e-90 ntd 2.4.2.6 F Nucleoside
LEHHPAIP_01862 3.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
LEHHPAIP_01863 8.9e-41 yrvD S Pfam:DUF1049
LEHHPAIP_01865 3.3e-35 S Phage derived protein Gp49-like (DUF891)
LEHHPAIP_01866 8.5e-20 K Helix-turn-helix XRE-family like proteins
LEHHPAIP_01867 8.8e-164 I alpha/beta hydrolase fold
LEHHPAIP_01868 1e-111 frnE Q DSBA-like thioredoxin domain
LEHHPAIP_01869 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEHHPAIP_01870 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEHHPAIP_01871 8.1e-79 F NUDIX domain
LEHHPAIP_01872 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
LEHHPAIP_01873 2.7e-67 yqkB S Belongs to the HesB IscA family
LEHHPAIP_01874 1.1e-25
LEHHPAIP_01876 1.6e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
LEHHPAIP_01877 3.7e-61 asp S Asp23 family, cell envelope-related function
LEHHPAIP_01878 3.6e-25
LEHHPAIP_01879 6.7e-93
LEHHPAIP_01880 4.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
LEHHPAIP_01881 4.9e-182 K Transcriptional regulator, LacI family
LEHHPAIP_01882 2.7e-197 gntT EG Gluconate
LEHHPAIP_01883 3.7e-235 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
LEHHPAIP_01887 4.9e-72
LEHHPAIP_01888 3.5e-20 E Zn peptidase
LEHHPAIP_01889 7.5e-41 ps115 K Helix-turn-helix XRE-family like proteins
LEHHPAIP_01890 2.6e-13
LEHHPAIP_01892 7.8e-12
LEHHPAIP_01893 1.1e-112 K BRO family, N-terminal domain
LEHHPAIP_01898 6.5e-33
LEHHPAIP_01902 8.7e-64 recT L RecT family
LEHHPAIP_01903 3.5e-67 S PDDEXK-like domain of unknown function (DUF3799)
LEHHPAIP_01904 1.1e-22 L Replication initiation and membrane attachment
LEHHPAIP_01905 7.3e-26
LEHHPAIP_01908 3.5e-38 S ORF6C domain
LEHHPAIP_01910 1e-28
LEHHPAIP_01918 2.4e-33
LEHHPAIP_01919 3.7e-75 S LemA family
LEHHPAIP_01920 1.9e-58
LEHHPAIP_01923 1e-58 S HicB_like antitoxin of bacterial toxin-antitoxin system
LEHHPAIP_01924 1.9e-55 ps333 L Terminase small subunit
LEHHPAIP_01925 3.6e-187 ps334 S Terminase-like family
LEHHPAIP_01926 3.1e-140 S Phage portal protein
LEHHPAIP_01927 4.4e-61 S Phage Mu protein F like protein
LEHHPAIP_01929 4.9e-42 S Domain of unknown function (DUF4355)
LEHHPAIP_01930 6.7e-32
LEHHPAIP_01931 6.8e-31 S Phage gp6-like head-tail connector protein
LEHHPAIP_01932 7.3e-36
LEHHPAIP_01933 2.4e-30 S Bacteriophage HK97-gp10, putative tail-component
LEHHPAIP_01934 2.5e-28 S Protein of unknown function (DUF3168)
LEHHPAIP_01935 7.2e-43 S Phage tail tube protein
LEHHPAIP_01936 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LEHHPAIP_01937 4.5e-146 potB P ABC transporter permease
LEHHPAIP_01938 6.5e-140 potC P ABC transporter permease
LEHHPAIP_01939 5.2e-206 potD P ABC transporter
LEHHPAIP_01940 2e-33
LEHHPAIP_01941 5.8e-53
LEHHPAIP_01942 2.2e-230 EGP Sugar (and other) transporter
LEHHPAIP_01943 3e-254 yfnA E Amino Acid
LEHHPAIP_01944 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
LEHHPAIP_01945 1.5e-98 gmk2 2.7.4.8 F Guanylate kinase
LEHHPAIP_01946 2.1e-81 zur P Belongs to the Fur family
LEHHPAIP_01947 3.1e-17 3.2.1.14 GH18
LEHHPAIP_01948 1e-148
LEHHPAIP_01949 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
LEHHPAIP_01950 7.8e-94 K Transcriptional regulator (TetR family)
LEHHPAIP_01951 5.3e-221 V domain protein
LEHHPAIP_01952 2.1e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEHHPAIP_01954 6.6e-35 S Transglycosylase associated protein
LEHHPAIP_01955 8.6e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEHHPAIP_01956 5e-127 3.1.3.73 G phosphoglycerate mutase
LEHHPAIP_01957 2e-115 dedA S SNARE associated Golgi protein
LEHHPAIP_01958 0.0 helD 3.6.4.12 L DNA helicase
LEHHPAIP_01959 1.3e-36 Q pyridine nucleotide-disulphide oxidoreductase
LEHHPAIP_01960 4.7e-157 EG EamA-like transporter family
LEHHPAIP_01961 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEHHPAIP_01962 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
LEHHPAIP_01963 1.7e-218 S cog cog1373
LEHHPAIP_01965 3.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LEHHPAIP_01966 8.2e-85 tra L Transposase and inactivated derivatives, IS30 family
LEHHPAIP_01968 2.4e-260 mco Q Multicopper oxidase
LEHHPAIP_01970 8.4e-189 EGP Major facilitator Superfamily
LEHHPAIP_01971 8.2e-70 K Transcriptional regulator, HxlR family
LEHHPAIP_01972 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LEHHPAIP_01973 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
LEHHPAIP_01974 1.7e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEHHPAIP_01975 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
LEHHPAIP_01976 3.7e-45 yktA S Belongs to the UPF0223 family
LEHHPAIP_01977 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LEHHPAIP_01978 0.0 typA T GTP-binding protein TypA
LEHHPAIP_01979 2.7e-222 ftsW D Belongs to the SEDS family
LEHHPAIP_01980 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
LEHHPAIP_01981 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
LEHHPAIP_01982 8.7e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEHHPAIP_01983 1.8e-195 ylbL T Belongs to the peptidase S16 family
LEHHPAIP_01984 5.8e-80 comEA L Competence protein ComEA
LEHHPAIP_01985 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
LEHHPAIP_01986 0.0 comEC S Competence protein ComEC
LEHHPAIP_01987 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
LEHHPAIP_01988 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
LEHHPAIP_01989 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEHHPAIP_01990 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEHHPAIP_01991 1.6e-163 S Tetratricopeptide repeat
LEHHPAIP_01992 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEHHPAIP_01993 1.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEHHPAIP_01994 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEHHPAIP_01995 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
LEHHPAIP_01996 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
LEHHPAIP_01997 4.9e-08
LEHHPAIP_01998 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEHHPAIP_01999 9.7e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEHHPAIP_02000 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEHHPAIP_02001 2.1e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHHPAIP_02002 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LEHHPAIP_02003 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEHHPAIP_02004 4.8e-87
LEHHPAIP_02006 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEHHPAIP_02007 2.4e-209 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
LEHHPAIP_02008 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEHHPAIP_02009 1.3e-35 ynzC S UPF0291 protein
LEHHPAIP_02010 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
LEHHPAIP_02011 4.6e-117 plsC 2.3.1.51 I Acyltransferase
LEHHPAIP_02012 2.7e-140 yabB 2.1.1.223 L Methyltransferase small domain
LEHHPAIP_02013 7.1e-49 yazA L GIY-YIG catalytic domain protein
LEHHPAIP_02014 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEHHPAIP_02015 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
LEHHPAIP_02016 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEHHPAIP_02017 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LEHHPAIP_02018 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEHHPAIP_02019 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEHHPAIP_02020 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
LEHHPAIP_02021 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LEHHPAIP_02022 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEHHPAIP_02023 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEHHPAIP_02024 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
LEHHPAIP_02025 2.3e-215 nusA K Participates in both transcription termination and antitermination
LEHHPAIP_02026 1e-44 ylxR K Protein of unknown function (DUF448)
LEHHPAIP_02027 1.3e-48 ylxQ J ribosomal protein
LEHHPAIP_02028 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEHHPAIP_02029 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEHHPAIP_02030 7.1e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEHHPAIP_02031 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LEHHPAIP_02032 2.9e-63
LEHHPAIP_02033 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEHHPAIP_02034 3.9e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEHHPAIP_02035 0.0 dnaK O Heat shock 70 kDa protein
LEHHPAIP_02036 2.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEHHPAIP_02037 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEHHPAIP_02038 2e-274 pipD E Dipeptidase
LEHHPAIP_02039 1.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
LEHHPAIP_02041 5.7e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEHHPAIP_02042 7.5e-58
LEHHPAIP_02043 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
LEHHPAIP_02044 6.7e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEHHPAIP_02045 9.4e-50
LEHHPAIP_02046 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEHHPAIP_02047 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEHHPAIP_02048 9.3e-166 yniA G Phosphotransferase enzyme family
LEHHPAIP_02049 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LEHHPAIP_02050 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEHHPAIP_02051 1.1e-262 glnPH2 P ABC transporter permease
LEHHPAIP_02052 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LEHHPAIP_02053 8.6e-70 yqeY S YqeY-like protein
LEHHPAIP_02054 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LEHHPAIP_02055 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEHHPAIP_02056 3.5e-263 argH 4.3.2.1 E argininosuccinate lyase
LEHHPAIP_02057 3.8e-83 bioY S BioY family
LEHHPAIP_02058 1.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEHHPAIP_02059 4.5e-183 phoH T phosphate starvation-inducible protein PhoH
LEHHPAIP_02060 1.2e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEHHPAIP_02061 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LEHHPAIP_02062 3.6e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEHHPAIP_02063 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
LEHHPAIP_02064 2.9e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LEHHPAIP_02065 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LEHHPAIP_02066 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEHHPAIP_02067 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEHHPAIP_02068 2.4e-220 patA 2.6.1.1 E Aminotransferase
LEHHPAIP_02069 4.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
LEHHPAIP_02070 8.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEHHPAIP_02071 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LEHHPAIP_02072 2e-29 S Protein of unknown function (DUF2929)
LEHHPAIP_02073 0.0 dnaE 2.7.7.7 L DNA polymerase
LEHHPAIP_02074 1.4e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LEHHPAIP_02075 3.5e-168 cvfB S S1 domain
LEHHPAIP_02076 9.1e-164 xerD D recombinase XerD
LEHHPAIP_02077 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEHHPAIP_02078 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEHHPAIP_02079 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEHHPAIP_02080 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEHHPAIP_02081 6e-100 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEHHPAIP_02082 3.3e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
LEHHPAIP_02083 1.4e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
LEHHPAIP_02084 2.5e-13 M Lysin motif
LEHHPAIP_02085 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LEHHPAIP_02086 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
LEHHPAIP_02087 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LEHHPAIP_02088 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEHHPAIP_02089 1.4e-234 S Tetratricopeptide repeat protein
LEHHPAIP_02090 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEHHPAIP_02091 0.0 yfmR S ABC transporter, ATP-binding protein
LEHHPAIP_02092 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEHHPAIP_02093 1.6e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEHHPAIP_02094 1.3e-111 hlyIII S protein, hemolysin III
LEHHPAIP_02095 6.4e-151 DegV S EDD domain protein, DegV family
LEHHPAIP_02096 1.8e-167 ypmR E lipolytic protein G-D-S-L family
LEHHPAIP_02097 8.2e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
LEHHPAIP_02098 8.4e-34 yozE S Belongs to the UPF0346 family
LEHHPAIP_02099 5.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEHHPAIP_02100 2.1e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEHHPAIP_02101 3.3e-118 dprA LU DNA protecting protein DprA
LEHHPAIP_02102 1e-95 L Belongs to the 'phage' integrase family
LEHHPAIP_02104 1.9e-19
LEHHPAIP_02105 6.8e-39 S Pfam:DUF955
LEHHPAIP_02106 9.3e-21 xre K Helix-turn-helix domain
LEHHPAIP_02116 5.6e-34 S Protein of unknown function (DUF1071)
LEHHPAIP_02117 7.4e-73 S Putative HNHc nuclease
LEHHPAIP_02118 1.9e-21 L Single-stranded DNA-binding protein
LEHHPAIP_02120 5.2e-28 K Conserved phage C-terminus (Phg_2220_C)
LEHHPAIP_02121 5.7e-40 dnaC 3.4.21.53 L IstB-like ATP binding protein
LEHHPAIP_02125 1.9e-52 S Protein of unknown function (DUF1064)
LEHHPAIP_02126 2.3e-184 L Belongs to the 'phage' integrase family
LEHHPAIP_02127 2.2e-122 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
LEHHPAIP_02128 1.2e-14
LEHHPAIP_02133 2.1e-18
LEHHPAIP_02135 1.1e-14 arpU S Phage transcriptional regulator, ArpU family
LEHHPAIP_02137 1.7e-55 S N-methyltransferase activity
LEHHPAIP_02138 4.3e-38
LEHHPAIP_02139 6.3e-42 L transposase activity
LEHHPAIP_02140 4.9e-192 ps334 S Terminase-like family
LEHHPAIP_02141 1.2e-139 S Phage portal protein
LEHHPAIP_02142 2e-85 S Phage Mu protein F like protein
LEHHPAIP_02143 1e-25 S sequence-specific DNA binding transcription factor activity
LEHHPAIP_02144 2.5e-41 S Domain of unknown function (DUF4355)
LEHHPAIP_02145 6.7e-32
LEHHPAIP_02146 6.8e-31 S Phage gp6-like head-tail connector protein
LEHHPAIP_02147 7.3e-36
LEHHPAIP_02148 2.4e-30 S Bacteriophage HK97-gp10, putative tail-component
LEHHPAIP_02149 2.5e-28 S Protein of unknown function (DUF3168)
LEHHPAIP_02150 7.2e-43 S Phage tail tube protein
LEHHPAIP_02151 4.6e-227 L Integrase core domain
LEHHPAIP_02152 1.5e-135 L Bacterial dnaA protein
LEHHPAIP_02153 2.5e-105 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LEHHPAIP_02154 6.3e-272 E ABC transporter, substratebinding protein
LEHHPAIP_02155 2.9e-144 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHHPAIP_02156 3.7e-131 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHHPAIP_02157 1.2e-165 oppD P Belongs to the ABC transporter superfamily
LEHHPAIP_02158 1.9e-137 P Belongs to the ABC transporter superfamily
LEHHPAIP_02159 6.2e-160 Q Imidazolonepropionase and related amidohydrolases
LEHHPAIP_02160 8.3e-223 dap2 3.4.19.1 E Prolyl oligopeptidase family
LEHHPAIP_02161 6.9e-191 Q Imidazolonepropionase and related amidohydrolases
LEHHPAIP_02162 4.7e-220 dapE 3.5.1.18 E Peptidase dimerisation domain
LEHHPAIP_02163 2.2e-81 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
LEHHPAIP_02164 3e-45 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
LEHHPAIP_02165 9.5e-39 S Cytochrome B5
LEHHPAIP_02166 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
LEHHPAIP_02167 1.7e-259 ytjP 3.5.1.18 E Dipeptidase
LEHHPAIP_02168 8.2e-216 uhpT EGP Major facilitator Superfamily
LEHHPAIP_02169 4.9e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
LEHHPAIP_02170 7e-131 ponA V Beta-lactamase enzyme family
LEHHPAIP_02171 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEHHPAIP_02172 1.4e-72
LEHHPAIP_02173 0.0 rafA 3.2.1.22 G alpha-galactosidase
LEHHPAIP_02174 1.5e-186 galR K Periplasmic binding protein-like domain
LEHHPAIP_02175 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
LEHHPAIP_02176 1.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEHHPAIP_02177 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
LEHHPAIP_02178 4.4e-147 f42a O Band 7 protein
LEHHPAIP_02179 3.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LEHHPAIP_02180 1e-153 yitU 3.1.3.104 S hydrolase
LEHHPAIP_02181 9.2e-39 S Cytochrome B5
LEHHPAIP_02182 1.3e-114 nreC K PFAM regulatory protein LuxR
LEHHPAIP_02183 5.2e-159 hipB K Helix-turn-helix
LEHHPAIP_02184 8.1e-57 yitW S Iron-sulfur cluster assembly protein
LEHHPAIP_02185 1.2e-271 sufB O assembly protein SufB
LEHHPAIP_02186 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
LEHHPAIP_02187 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEHHPAIP_02188 1.7e-240 sufD O FeS assembly protein SufD
LEHHPAIP_02189 1.9e-144 sufC O FeS assembly ATPase SufC
LEHHPAIP_02190 2.8e-31 feoA P FeoA domain
LEHHPAIP_02191 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LEHHPAIP_02192 6.3e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LEHHPAIP_02193 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEHHPAIP_02194 6.7e-60 ydiI Q Thioesterase superfamily
LEHHPAIP_02195 7.1e-109 yvrI K sigma factor activity
LEHHPAIP_02196 1.3e-205 G Transporter, major facilitator family protein
LEHHPAIP_02197 0.0 S Bacterial membrane protein YfhO
LEHHPAIP_02198 3.3e-103 T Ion transport 2 domain protein
LEHHPAIP_02199 9.9e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
LEHHPAIP_02201 5.9e-23 S Phage tail assembly chaperone protein, TAC
LEHHPAIP_02202 7.7e-23 S Phage tail assembly chaperone protein, TAC
LEHHPAIP_02203 5.2e-181 yfeX P Peroxidase
LEHHPAIP_02204 3.7e-205 amtB P ammonium transporter
LEHHPAIP_02205 6.8e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
LEHHPAIP_02206 8.6e-84 yvbK 3.1.3.25 K GNAT family
LEHHPAIP_02207 1.7e-91
LEHHPAIP_02208 4.1e-121 pnb C nitroreductase
LEHHPAIP_02209 2.4e-75 ogt 2.1.1.63 L Methyltransferase
LEHHPAIP_02210 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
LEHHPAIP_02211 6.8e-67 S Protein of unknown function (DUF3021)
LEHHPAIP_02212 6e-76 K LytTr DNA-binding domain
LEHHPAIP_02213 1.1e-92 K Acetyltransferase (GNAT) family
LEHHPAIP_02216 2.4e-178 ycsG P Natural resistance-associated macrophage protein
LEHHPAIP_02217 5.8e-103 ycsF S LamB/YcsF family
LEHHPAIP_02218 3.5e-207 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
LEHHPAIP_02219 3.8e-38 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEHHPAIP_02220 3.1e-107 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LEHHPAIP_02221 7.7e-84 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
LEHHPAIP_02222 2.2e-41 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LEHHPAIP_02224 6.2e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LEHHPAIP_02225 3.3e-110 tesE Q hydratase
LEHHPAIP_02226 5.3e-64 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEHHPAIP_02227 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEHHPAIP_02228 1.6e-296 mco Q Multicopper oxidase
LEHHPAIP_02229 1.7e-127 L PFAM Integrase catalytic region
LEHHPAIP_02230 8.7e-113 fic S Fic/DOC family
LEHHPAIP_02231 2e-129 L Belongs to the 'phage' integrase family
LEHHPAIP_02232 4e-19
LEHHPAIP_02235 2.2e-153
LEHHPAIP_02237 1.6e-76 L Resolvase, N terminal domain
LEHHPAIP_02238 3.8e-10 L Resolvase, N terminal domain
LEHHPAIP_02239 2.8e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LEHHPAIP_02242 1.4e-18 L Transposase IS66 family
LEHHPAIP_02245 4.9e-60 XK27_01125 L PFAM IS66 Orf2 family protein
LEHHPAIP_02246 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
LEHHPAIP_02247 4.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
LEHHPAIP_02248 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEHHPAIP_02249 1.2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEHHPAIP_02250 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
LEHHPAIP_02251 9.7e-178 yagE E amino acid
LEHHPAIP_02252 4.6e-52 yagE E amino acid
LEHHPAIP_02253 3.8e-84 dps P Belongs to the Dps family
LEHHPAIP_02254 0.0 pacL 3.6.3.8 P P-type ATPase
LEHHPAIP_02255 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
LEHHPAIP_02256 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LEHHPAIP_02257 8.9e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LEHHPAIP_02258 8.2e-224 mdtG EGP Major facilitator Superfamily
LEHHPAIP_02259 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
LEHHPAIP_02260 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEHHPAIP_02261 4.2e-49 L Transposase IS200 like
LEHHPAIP_02262 2.5e-185 L transposase, IS605 OrfB family
LEHHPAIP_02265 1.1e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
LEHHPAIP_02266 3.7e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LEHHPAIP_02267 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
LEHHPAIP_02268 0.0 trxB2 1.8.1.9 C Thioredoxin domain
LEHHPAIP_02269 4.9e-273 pipD E Dipeptidase
LEHHPAIP_02270 2.5e-311 yjbQ P TrkA C-terminal domain protein
LEHHPAIP_02271 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LEHHPAIP_02272 6.6e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEHHPAIP_02273 4.3e-86
LEHHPAIP_02274 1.1e-264 L PFAM Integrase catalytic region
LEHHPAIP_02275 4.7e-35
LEHHPAIP_02276 3.5e-61 K DNA-templated transcription, initiation
LEHHPAIP_02277 2.6e-40 K Transcriptional regulator, HxlR family
LEHHPAIP_02278 4.9e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LEHHPAIP_02279 9e-140 epsB M biosynthesis protein
LEHHPAIP_02280 2.8e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
LEHHPAIP_02281 2.2e-50 pglC M Bacterial sugar transferase
LEHHPAIP_02282 1.5e-83 lsgF M Glycosyl transferase family 2
LEHHPAIP_02283 2.1e-33 2.4.1.166 GT2 M Glycosyltransferase like family 2
LEHHPAIP_02285 6.1e-67 cps2I S Psort location CytoplasmicMembrane, score
LEHHPAIP_02286 4.8e-38 M Glycosyltransferase sugar-binding region containing DXD motif
LEHHPAIP_02287 5.3e-45 cpsJ M Glycosyltransferase like family 2
LEHHPAIP_02288 6.2e-38 M Glycosyltransferase sugar-binding region containing DXD motif
LEHHPAIP_02289 2.4e-60 S Glycosyltransferase, group 2 family protein
LEHHPAIP_02290 2.3e-07 M Glycosyl transferases group 1
LEHHPAIP_02291 1.3e-47 Z012_10770 M Domain of unknown function (DUF1919)
LEHHPAIP_02292 5.6e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEHHPAIP_02293 2e-36 S Uncharacterised protein family (UPF0236)
LEHHPAIP_02294 1.1e-33 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
LEHHPAIP_02295 2e-32 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
LEHHPAIP_02296 9.1e-126 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
LEHHPAIP_02297 3.7e-67 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
LEHHPAIP_02298 5.5e-138 S Belongs to the UPF0246 family
LEHHPAIP_02299 2.1e-137 S Membrane
LEHHPAIP_02300 6.8e-74 4.4.1.5 E Glyoxalase
LEHHPAIP_02301 3.9e-159 mleR K LysR family
LEHHPAIP_02302 9.4e-253 yjjP S Putative threonine/serine exporter
LEHHPAIP_02303 4.7e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
LEHHPAIP_02304 6.5e-271 emrY EGP Major facilitator Superfamily
LEHHPAIP_02305 9.4e-186 I Alpha beta
LEHHPAIP_02306 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
LEHHPAIP_02307 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEHHPAIP_02309 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LEHHPAIP_02310 2.7e-121 S Domain of unknown function (DUF4811)
LEHHPAIP_02311 7.2e-270 lmrB EGP Major facilitator Superfamily
LEHHPAIP_02312 3.4e-74 merR K MerR HTH family regulatory protein
LEHHPAIP_02313 2.9e-57
LEHHPAIP_02314 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEHHPAIP_02315 8.3e-221 S CAAX protease self-immunity
LEHHPAIP_02316 1e-108 glnP P ABC transporter permease
LEHHPAIP_02317 2.4e-110 gluC P ABC transporter permease
LEHHPAIP_02318 7.5e-152 glnH ET ABC transporter
LEHHPAIP_02319 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEHHPAIP_02320 5.5e-83 usp1 T Belongs to the universal stress protein A family
LEHHPAIP_02321 8.4e-109 S VIT family
LEHHPAIP_02322 2.5e-116 S membrane
LEHHPAIP_02323 5.5e-164 czcD P cation diffusion facilitator family transporter
LEHHPAIP_02324 1.6e-123 sirR K iron dependent repressor
LEHHPAIP_02325 1e-30 cspC K Cold shock protein
LEHHPAIP_02326 2e-127 thrE S Putative threonine/serine exporter
LEHHPAIP_02327 1e-81 S Threonine/Serine exporter, ThrE
LEHHPAIP_02328 4.4e-118 lssY 3.6.1.27 I phosphatase
LEHHPAIP_02329 6.6e-09 2.3.1.128 J Acetyltransferase (GNAT) domain
LEHHPAIP_02330 1.5e-275 lysP E amino acid
LEHHPAIP_02331 1.1e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LEHHPAIP_02337 9.8e-186 2.7.13.3 T GHKL domain
LEHHPAIP_02338 1.8e-59 S Double zinc ribbon
LEHHPAIP_02339 2.8e-49 agrA K LytTr DNA-binding domain
LEHHPAIP_02340 3.6e-47
LEHHPAIP_02341 2.2e-09 S zinc-ribbon domain
LEHHPAIP_02345 1.3e-28 ebh D nuclear chromosome segregation

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)