GCA_001075325.1 - 12 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

JUNV01000360.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	lanthipeptide-class-ii	1	6,474	salivaricin A	RiPP:Lanthipeptide	50%

JUNV01000038.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 54.1	NRPS-like	1	5,970	qinichelins	NRP	22%

JUNV01000477.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 114.1	RiPP-like	1,416	13,512

JUNV01000651.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 245.1	T3PKS	1	6,299

JUNV01000748.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 313.1	siderophore	1	13,664	aerobactin	Other	83%

JUNV01000771.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 332.1	RiPP-like	1	5,863

JUNV01000914.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 442.1	RiPP-like	11,363	21,590

JUNV01000098.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 531.1	RiPP-like	1	8,210

JUNV01000105.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 594.1	RiPP-like	11,367	22,398

JUNV01000181.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 646.1	T1PKS,NRPS	1	38,097	yersiniabactin	NRP + Polyketide	17%

JUNV01000242.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 687.1	redox-cofactor	1	10,477	lankacidin C	NRP + Polyketide	13%

JUNV01000304.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 737.1	thiopeptide	1	18,723

Compact view

JUNV01000360.1 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 6,474 nt. (total: 6,474 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Lanthipeptides

KnownClusterBlast

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Similar known gene clusters

Lanthipeptides

Core peptide predictions

No core peptides found.

JUNV01000038.1 - Region 1 - NRPS-like

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Location: 1 - 5,970 nt. (total: 5,970 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 5970:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg54_1

Search NORINE for peptide: strict or relaxed

AMP-binding (1..363): ser

NRPSPredictor2: ser

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

JUNV01000477.1 - Region 1 - RiPP-like

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Location: 1,416 - 13,512 nt. (total: 12,097 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JUNV01000651.1 - Region 1 - T3PKS

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Location: 1 - 6,299 nt. (total: 6,299 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JUNV01000748.1 - Region 1 - siderophore

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Location: 1 - 13,664 nt. (total: 13,664 nt) Show pHMM detection rules used

Region on contig edge.

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

JUNV01000771.1 - Region 1 - RiPP-like

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Location: 1 - 5,863 nt. (total: 5,863 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JUNV01000914.1 - Region 1 - RiPP-like

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Location: 11,363 - 21,590 nt. (total: 10,228 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JUNV01000098.1 - Region 1 - RiPP-like

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Location: 1 - 8,210 nt. (total: 8,210 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JUNV01000105.1 - Region 1 - RiPP-like

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Location: 11,367 - 22,398 nt. (total: 11,032 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

No matches found.

JUNV01000181.1 - Region 1 - NRPS,T1PKS

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Location: 1 - 38,097 nt. (total: 38,097 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

KnownClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 38097:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (ohmal) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 33969:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (ohmal) + (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg646_7

Search NORINE for peptide: strict or relaxed

AMP-binding (573..966): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg646_8

PKS_AT (552..842): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 62.5%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 133.0
Methoxymalonyl-CoA: 49.3
inactive: 45.5
Methylmalonyl-CoA: 42.8
Benzoyl-CoA: 42.7
Propionyl-CoA: 33.6
Isobutyryl-CoA: 30.8
fatty_acid: 25.6
Acetyl-CoA: 25.3
2-Methylbutyryl-CoA: 24.6
3-Methylbutyryl-CoA: 19.5
CHC-CoA: 16.3
trans-1,2-CPDA: 11.2
Ethylmalonyl-CoA: 6.5

ctg646_12

Search NORINE for peptide: strict or relaxed

AMP-binding (20..422): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVLCK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

JUNV01000242.1 - Region 1 - redox-cofactor

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Location: 1 - 10,477 nt. (total: 10,477 nt) Show pHMM detection rules used

Region on contig edge.

redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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KnownClusterBlast

Similar known gene clusters

JUNV01000304.1 - Region 1 - thiopeptide

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Location: 1 - 18,723 nt. (total: 18,723 nt) Show pHMM detection rules used

Region on contig edge.

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Thiopeptides

KnownClusterBlast

Thiopeptide predictions

No core peptides found.

Similar known gene clusters

No matches found.

Thiopeptides

Core peptide predictions

No core peptides found.